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| 1 | Progress in transdermal drug delivery systems for cancer therapy显示文摘Transdermal drug delivery is an appealing option except for oral and hypodermic administration.With the advancement of skin penetration strategies,various anticancer therapeutics ranging from liphilic small-molecule drugs to hydrophilic biomacromolecules,can be administered transdermally,offering an optional regimen to treat skin cancers.In addition,the activation of the skin immune systems can also assist the treatment of distal sites.Current approaches on enhancing the transdermal delivery efficacy of anticancer drugs are summarized in this review.We also survey recent advances in micro-and nanotechnology-based transdermal formulations for cancer treatment,such as chemotherapy,gene therapy,immunotherapy,phototherapy and combination therapy.New penetration enhancers,materials,formulations and their hypothesized mechanisms for transdermal delivery are highlighted.Advantages and limitations regarding the state-of-the-art transdermal delivery technologies,as well as future perspective are also discussed. | Tianyue Jiang Guo Xu Guojun Chen Yu Zheng Bingfang He Zhen Gu | 2020 | Nano Research2020，13，7： | 5 |
| 2 | 通过使用转基因小鼠来了解沃尔夫/附睾管发育的正常与异常显示文摘沃尔夫/附睾管的发育对雄性生殖系统的正常功能以及相应的男性生育力至关重要。附睾的发育过程复杂,它起始于一个短暂的胚肾,而后中肾形成,中肾进一步在雄激素与生长激素的影响下经历形态发生最终形成附睾。因此,要了解它完整的发育过程需要一个广泛的、多学科的视角。这篇综述着力探讨表现出沃尔夫管与中肾发育异常的小鼠模型、这些小鼠模型对了解生殖道发育的重要性、以及这些模型如何帮助我们了解诸如先天性肾脏和尿路畸形(CAKUT)这样的人类临床异常表现。 | Aki Murashima Bingfang Xu Barry T Hinton | 2015 | Asian Journal of Andrology2015，17，5： | 4 |
| 3 | Cryopreservation of Pollen by Vitrification in Brassica显示文摘CryopreservationofPolenbyVitrificationinBrasicaXuBingfang,HanHongmei,ZhengCongyi,SunMengxiangColegeofLifeSciences,WuhanUnive... | Xu Bingfang Han Hongmei Zheng Congyi Sun Mengxiang | 1997 | Wuhan University Journal of Natural Sciences1997，2，1： | 2 |
| 4 | Combining Spot4-vegetation and meteorological data derived land cover map in China显示文摘 | Wu Bingfang Xu Wenting Huang Huiping | 2004 | IEEE International Geoscience and Remote Sensing Symposium Proceedings2004，4，： | 1 |
| 5 | Differential diagnosis of cervical nerve compression syndrome of the external intervertebral foramen显示文摘The aim of the present research is to study the mechanism of cervical nerve compression syndrome of the external intervertebral foramen and its differential diagnosis with cervical spondylosis.Diagnostic treatment with muscle relaxant,vasodilator,neurotrophic medicine and celecoxib(COX)-2 inhibitor were performed in 20 patients with cervical nerve compression syndrome of the external intervertebral foramen and 20 patients with cervical spondylosis confirmed by operation.Diagnostic local block therapy was performed additionally in cases showing little effect after diagnostic treatment.All the patients were followed up postoperatively for more than one year.Fifteen cases with cervical nerve compression syndrome of the external intervertebral foramen were healed by the diagnostic treatment.The other five cases had a short-term remission and there was no recurrence after diagnostic local block therapy.Diagnostic treatment led to short-term alleviation of the symptom in 20 cases with cervical spondylosis confirmed by operation,the results of which was far from satisfactory and operation was undertaken finally in all the 20 cases.The etiology of cervical nerve compression syndrome of the external intervertebral foramen lies in the compression of the cervical plexus,brachial plexus and cervical dorsal rami by the tendinous decussating fibers of the scalenus anticus,medius,minimus and the posterior muscles of the neck.Diagnostic treatment was propitious to differentiate cervical nerve compression syndrome of the external intervertebral foramen from cervical spondylosis. | WANG Jinwu NI Weifeng LI Qi XU Jianguang ZHU Haibo ZHAO Binghui GUO Shangchun ZENG Bingfang | 2007 | Frontiers of Medicine2007，1，2： | 1 |
| 6 | Methyl jasmonate induced expression of the tobacco putrescine N-methyltransferase genes requires both G-box and GCC-motif elements显示文摘 | Bingfang Xu Michael Timko | 2004 | Plant Molecular Biology2004，，5： | 1 |
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