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| 1 | Kaempferia parviflora ethanol extract improves self-assessed sexual health in men:a pilot study显示文摘Background: Sexual health positively correlates with overall wellbeing. Existing therapeutics to enhance male sexual health are limited by factors that include responsiveness, adherence and adverse effects. As the population ages, safe and effective interventions that preserve male sexual function are needed.Published research suggests that various preparations of Kaempferia parviflora, a plant in the Zingiberaceae(ginger) family, support cardiovascular health and may ameliorate erectile function.Objective: The aim of this study was to examine the effects of KaempMax^(TM), an ethanol extract of the K. parviflora rhizome, on erectile function in healthy middle-aged and older men.Design, setting, participants and interventions: We conducted an open-label, one-arm study on 14 generally healthy males aged 50–68 years with self-reported mild erectile dysfunction, who were not using prescription treatments. Participants took 100 mg KaempMax^(TM)daily for 30 days.Main outcome measures: Evaluations were conducted at baseline and on the final study assessment.Primary efficacy analyses included the International Index of Erectile Function(IIEF); secondary efficacy analyses included the Global Assessment Question about erectile function.Results: Thirteen participants completed the 30-day study. Supplementation with KaempMax^(TM)resulted in statistically significant improvements in erectile function, intercourse satisfaction and total scores on the IIEF questionnaire. KaempMax^(TM)was well tolerated and exhibited an excellent safety profile.Conclusion: Our results suggest that KaempMax^(TM)may improve erectile function in healthy middle-aged and older men. While the effects were not as pronounced as what might be seen with prescription medication, most participants found them satisfactory. Additional, longer and placebo-controlled clinical trials will be needed.Trial registration: Clinicaltrials.gov identifier NCT03389867. | Richard A.Stein Kira Schmid Jowell Bolivar Andrew G.Swick Steven V.Joyal Steven P.Hirsh | 2018 | Journal of Integrative Medicine2018，16，4： | 4 |
| 2 | Phylogenetic position of foraminifera inferred from LSU rRNA gene sequence显示文摘 | Pawlowski J Bolivar I Guiard-Maffia J | 1994 | Molecular Biology and Evolution1994，11，6： | 1 |
| 3 | Design and construction of expression plasmid vectors in Escherichia coli 显示文摘 | Balbas P Bolivar F | 1990 | Meth Enzymol1990，185，： | 1 |
| 4 | Early origin of foraminifera suggested by SSU rRNA gene sequences显示文摘 | Pawlowski J Bolivar I Fahni J F | 1996 | Molecular Biology and Evolution1996，13，3： | 1 |
| 5 | Inactivation of the 25-hydroxyvitamin D I alpha-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal andmioeral horaeostasis显示文摘 | Panda DK Miao D Bolivar I | 2004 | J Biol Chem2004，279，16： | 1 |
| 6 | The influence of CCL3L1 gene containing segmental duplications on HIV-1/AIDS susceptibility 显示文摘 | Gonzalez E Kulkarni H Bolivar H | 2005 | Science2005，307，5714： | 1 |
| 7 | Purification and stabilization of ricin B from tobacco hairy root culture medium by aqueous two-phase extraction 显示文摘 | Chenming Zhang Fabricio Medina Bolivar Scott Buswell | 2005 | Journal of Biotechnology2005，117，： | 1 |
| 8 | Angle-dependent THz tomography-characterization of thin ceramic oxide films for fuel cell applications显示文摘 | Brucherseifer M Bolivar P H Klingenberg H | 2001 | Applied Physics B2001，72，3： | 1 |
| 9 | Design and construction of expression plasmid vectors in Escherichia coli显示文摘 | Balbas P Bolivar F | | 0，，： | 1 |
| 10 | Stability of anthoeyanin-based aqueous extracts of Andean Purple corn and red-freshed sweet potato compared to synthetic and natural colorants显示文摘 | Bolivar A Cevallos-Casals Luis Cisneros-Zevallos | 2004 | Food Chem2004，86，： | 1 |
| 11 | Extreme difference in rates of molecular evolution of foraminifera revealed by comparison of ribosomal DNA sequences and the fossil record显示文摘 | Pawlowski J Bolivar I Fahni J F | 1997 | Molecular Biology and Evolution1997，14，5： | 1 |
| 12 | The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility显示文摘 | Gonzalez E Kulkarni H Bolivar H | 2005 | Science2005，307，5714： | 1 |
| 13 | Moxalactam plus ticarcillin or tobramycin for treatment of febrile episodes in neutropenic cancer patients显示文摘 | Fainstein V Bodey GP Bolivar R | 1984 | Arch Intern Med1984，144，9： | 1 |
| 14 | Integrated planar terahertz resonators for femtomolar sensitivity label-free detection of DNA hybr-idization显示文摘 | NAGEL M BOLIVAR P H BRUCHERSEIFER M | 2002 | Appl Optics2002，41，10： | 1 |
| 15 | Development and Characterization of Novel Starch and Alkyl Ketene Dimer Microeellular Foam Particles 显示文摘 | BOLIVAR A I VENDITTI R A V PAWLAK J J | 2007 | Carbohydrate Polymers2007，69，： | 1 |
| 16 | Integrated THz technology for label - free genetic diagnostics 显示文摘 | Nagel M Bolivar P H Brucherseifer M | 2002 | Appl Phys Lett2002，80，： | 1 |
| 17 | The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility显示文摘 | Gonzalez E Kulkarni H Bolivar H | 2005 | Science2005，307，5714： | 1 |
| 18 | Dynamic Adaptive Sliding Mode Output Tracking Control of a Class of Nonlinear Systems显示文摘 | Bolivar M R Zinober A S I Sira-Ramirez H | 1997 | International Journal of Robust and Nonlinear Control1997，7，4： | 1 |
| 19 | Label-free probing of genes by time domain terahertz sensing显示文摘 | Bolivar P H Brucherseifer M Nagel M | | 0，，21： | 1 |
| 20 | Stability of anthocyanin- based aqueous extracts of Andean purple corn and red-fleshed sweet potato compared to synthetic and natural colorants显示文摘 | Bolivar A Cevallos C Luis C Z | 2004 | Food Chem2004，6，： | 1 |
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