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| 1 | Role of complex organic arsenicals in food in aggregate exposure to arsenic显示文摘For much of the world's population, food is the major source of exposure to arsenic.Exposure to this non-essential metalloid at relatively low levels may be linked to a wide range of adverse health effects. Thus, evaluating foods as sources of exposure to arsenic is important in assessing risk and developing strategies that protect public health. Although most emphasis has been placed on inorganic arsenic as human carcinogen and toxicant, an array of arsenic-containing species are found in plants and animals used as foods. Here,we 2evaluate the contribution of complex organic arsenicals(arsenosugars, arsenolipids,and trimethylarsonium compounds) that are found in foods and consider their origins,metabolism, and potential toxicity. Commonalities in the metabolism of arsenosugars and arsenolipids lead to the production of di-methylated arsenicals which are known to exert many toxic effects. Evaluating foods as sources of exposure to these complex organic arsenicals and understanding the formation of reactive metabolites may be critical in assessing their contribution to aggregate exposure to arsenic. | David J.Thomas Karen Bradham | 2016 | Journal of Environmental Sciences2016，28，11： | 18 |
| 2 | Curcumin blocks cytokinemediated NF-κB activation and proinflammatory gene expression by inhibiting inhibitory factor I-κB kinase activity显示文摘 | Jobin C Bradham CA Russo MP | 1999 | J Immunol1999，163，6： | 1 |
| 3 | Robotic upper-limb neurorehabilitation in chronic stroke patients显示文摘 | Macclellan LR Bradham DD whitan J | 2005 | J Rehabil Res Dev2005，42，6： | 1 |
| 4 | TNF-alpha and myocardial matrix metalloproteinase in heart failure, relationgship to LV remodeling显示文摘 | Bradham WS Moe G Wendt KA | 2002 | Am J Physiol Heart Circ Physiol2002，282，4： | 1 |
| 5 | TNF-alpha and myocardial matrix metalloproteinases in heart failure:relationship to LV remodeling显示文摘 | Bradham WS Moe G Wendt KA | | 0，，： | 1 |
| 6 | TNFa-and myocardial matrix metalloproteinases in heart failure relationship to LV remodeling 显示文摘 | Bradham WS Moe G Wendt KA | 2002 | Am J Physiol Heart Circ Physiol2002，282，： | 1 |
| 7 | Connective tissue growth factor:a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10显示文摘 | Bradham DM Igarashi A Potter RL Grotendorst GR | 1991 | J Cell Biol1991，114，6： | 1 |
| 8 | Tumor necrosis factorand myocardial remodeling in progression of heart failure;a current perspective 显示文摘 | Bradham WS Bozkurt B Gunasinghe H | 2002 | Cardiovasc Res2002，53，： | 1 |
| 9 | Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair显示文摘 | IGARASHI A OKOCHI H BRADHAM D M | 1993 | Mol Biol Cell 41993，4，6： | 1 |
| 10 | Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair显示文摘 | Igarashi A Okochi H Bradham DM | 1993 | Mol Biol Cell1993，4，6： | 1 |
| 11 | Connective tissue growth factor: a cysteine - rich mitogen secreted by human vascular endothelial cells is related to the SRC - induced immediate early gene product CEF - 10 显示文摘 | BRADHAM D M IGAMSHI A POTFER R L | 1991 | J Cell Biol1991，114，： | 1 |
| 12 | connetive tissue growth uture:a cysteine-rich mitagen secreted by human endothethlial cells is related to the SRC-induced immediate early gene productCEF- 10 显示文摘 | Bradham DM Igarashi A Poller RL | | J Cell Biol0，114，6： | 1 |
| 13 | Connective tissue growth factor:a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10显示文摘 | Bradham DM Igarashi A Potter RL | 1991 | J Cell Biol1991，114，6： | 1 |
| 14 | Robotic up- per-limb neurorehabilitation in chronic stroke patients 显示文摘 | Macclellan LR Bradham DD Whitan J | 2005 | J Re- habil Res Dev2005，42，6： | 1 |
| 15 | Connective tissue growth factor:, a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10显示文摘 | Bradham DM Igarashi A Potter RL | 1991 | J Cell Biol1991，114，6： | 1 |
| 16 | Tumor necrosis factor-alpha and myocardial remodeling in progression of heart failure: a current perspective 显示文摘 | Bradham W S Bozkurt B Gunasinghe H | 2002 | Cardiovasc Res2002，53，4： | 1 |
| 17 | In vivo cartilage formation from growth factor modulated articular chondrocytes显示文摘 | Bradham DM Horton WE | 1998 | Clin orthorp1998，352，： | 1 |
| 18 | Connective tissue growth factor : A eydteine - rich mitogen secreted by human vascular endothelial cells is related to the SRC- induced immediate early gene product CEF - 10 显示文摘 | Bradham DM Igarashl A Potter RL | 1991 | J Cell Biol1991，114，： | 1 |
| 19 | Connective tissue growth factor:a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10显示文摘 | Bradham DM Igarashi A Potter RL | 1991 | J Cell Biol1991，114，6： | 1 |
| 20 | Segmental Bioelectrical Impedance Analysis:Theory and Application of a New Technique 显示文摘 | Organ L W Bradham G B Gore D W | 1994 | J Appl physiol1994，77，： | 1 |
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