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| 1 | Counter-regulatory phosphatases TNAP and NPP1 temporally regulate tooth root cementogenesis显示文摘Cementum is critical for anchoring the insertion of periodontal ligament fibers to the tooth root. Several aspects of cementogenesis remain unclear, including differences between acellular cementum and cellular cementum, and between cementum and bone.Biomineralization is regulated by the ratio of inorganic phosphate(Pi) to mineral inhibitor pyrophosphate(PPi), where local Piand PPi concentrations are controlled by phosphatases including tissue-nonspecific alkaline phosphatase(TNAP) and ectonucleotide pyrophosphatase/phosphodiesterase 1(NPP1). The focus of this study was to define the roles of these phosphatases in cementogenesis. TNAP was associated with earliest cementoblasts near forming acellular and cellular cementum. With loss of TNAP in the Alpl null mouse, acellular cementum was inhibited, while cellular cementum production increased, albeit as hypomineralized cementoid. In contrast, NPP1 was detected in cementoblasts after acellular cementum formation, and at low levels around cellular cementum. Loss of NPP1 in the Enpp1 null mouse increased acellular cementum, with little effect on cellular cementum.Developmental patterns were recapitulated in a mouse model for acellular cementum regeneration, with early TNAP expression and later NPP1 expression. In vitro, cementoblasts expressed Alpl gene/protein early, whereas Enpp1 gene/protein expression was significantly induced only under mineralization conditions. These patterns were confirmed in human teeth, including widespread TNAP, and NPP1 restricted to cementoblasts lining acellular cementum. These studies suggest that early TNAP expression creates a low PPienvironment promoting acellular cementum initiation, while later NPP1 expression increases PPi, restricting acellular cementum apposition. Alterations in PPihave little effect on cellular cementum formation, though matrix mineralization is affected. | Laura E Zweifler Mudita K Patel Francisco H Nociti Jr Helen F Wimer Jose L Milln Martha J Somerman Brian L Foster | 2015 | International Journal of Oral Science2015，7，1： | 5 |
| 2 | The Role of the Operating Room Nurse Manager in the Successful Implementation of Preoperative Briefings and Postoperative Debriefings in the VHA Medical Team Training Program显示文摘 | Lori D. Robinson Douglas E. Paull Lisa M. Mazzia Lisa Falzetta James Hay Julia Neily Peter D. Mills Brian Carney James P. Bagian | 2010 | Journal of PeriAnesthesia Nursing2010，，： | 2 |
| 3 | A Tale of Two (Anal Fistula) Plugs: Is there a Difference in Short-Term Outcomes?显示文摘 | Buchberg Brian Masoomi Hossein Choi John Bergman Herlinda Mills Steven Stamos Michael J | 2010 | The American Surgeon2010，，10： | 2 |
| 4 | Markedly Elevated Levels of Vascular Endothelial Growth Factor in Malignant Ascites显示文摘 | Brian K. Zebrowski MD Wenbiao Liu MD Karen Ramirez BS Yoshito Akagi MD Gordon B. Mills MD Lee M. Ellis MD | 1999 | Annals of Surgical Oncology1999，，4： | 2 |
| 5 | Review of Methods of Odour Control显示文摘 | Brian Mills | 1995 | Filtration Seperation1995，，2： | 1 |
| 6 | Prognostic Impact of the 2009 UICC/AJCC TNM Staging System for Renal Cell Carcinoma with Venous Extension显示文摘 | Juan I. Martínez-Salamanca William C. Huang Isabel Millán Roberto Bertini Fernando J. Bianco Joaquin A. Carballido Gaetano Ciancio Carlos Hernández Felipe Herranz Axel Haferkamp Markus Hohenfellner Brian Hu Theresa Koppie Claudio Martínez-Ballesteros Fran | 2010 | European Urology2010，，1： | 1 |
| 7 | Review of methods of odour control显示文摘 | Brian Mills | 1995 | Filtration and Separation1995，，2： | 1 |
| 8 | Application of intelligent CNC in grinding显示文摘 | Brian Rowe W Li Y Mills B | 1996 | Computers in Industry1996，31，1： | 1 |
| 9 | Review of Methods of Odour Control 显示文摘 | Brian Mills | 1995 | Filtration&Seperation1995，，2： | 1 |
| 10 | Nucleotide sequence of the 7K gene of carnation latent virus显示文摘 | Gary D. Foster Brian M. Meehan Peter R. Mills | 1990 | Plant Molecular Biology1990，，6： | 1 |
| 11 | The impact and outcomes of establishing an integrated interdisciplinary surgical team to care for the diabetic foot显示文摘 | David G. Armstrong Manish Bharara Matthew White Brian Lepow Sugam Bhatnagar Timothy Fisher Heather R. Kimbriel Jodi Walters Kaoru R. Goshima John Hughes Joseph L. Mills | 2012 | Diabetes Metab Res Rev2012，，6： | 1 |
| 12 | A new method for measurement of blood pressure, heart rate, and activity in the mouse by radiotelemetry 显示文摘 | Perry A Mills Daniel A Huetteman Brian P Brockway | 2000 | J Appl Physiol2000，88，： | 1 |
| 13 | Effects of cross-training on markers of insulin resistance/hyperinsulinemia显示文摘 | M. BRIAN WALLACE BRETT D. MILLS CAROL L. BROWNING | 1997 | Medicine & Science in Sports & Exercise1997，，9： | 1 |
| 14 | Increasing the value of weather-related warnings显示文摘Despite advances in forecasting and emergency preparedness, weather related disasters continue to cost many lives, to displace populations and to cause wide-spread damage. Therefore, High Impact Weather Project (HIWeather), a 10-year research project (http://gffzz72c37a797ca44d97skvnx9kx9pk566cwx.ffgz.tsg.suse.edu.cn/en/resources/buHetin/hiweather-10-yearresearch- project), was established in 2016 by WM0 (World Meteorology Organization) WWRP (World Weather Research Program: http://gffzz74e393fd09b145d8skvnx9kx9pk566cwx.ffgz.tsg.suse.edu.cn/pages/prog/arep/wwrp/new/wwrp_new_en. html). HIWeather aimed at achieving dramatic improvements in the effectiveness of weather-related hazard warnings, following recent advancement in numerical weather prediction at km-scale and in disaster risk reduction. The implementation plan was developed under the concept of warning chain, which comprises all components and the connections between to a successful weather-hazards warning: observations, weather forecast, hazard forecast, impact forecast, the generation of warnings and decision making (Fig. 1). A successful warning relies on information produced by the meteorological and related physical sciences, thus its effectiveness of delivery depends on applications of social, behavioral and economic sciences. The workshop of WM0 High Impact Weather Project was held in Beijing during 20-22 November of 2018, attracted a diverse and interdisciplinary group of over 70 scientists from 25 countries in the broad field of physical and social science, during which all elements of the warning chain were discussed critically. | Qinghong Zhang Liye Li Beth Ebert Brian Golding David Johnston Brian Mills Shannon Panchuk Sally Potter Michael Riemer Juanzhen Sun Andrea Taylor Sarah Jones Paolo Ruti Julia Keller | 2019 | Science Bulletin2019，64，10： | 1 |
| 15 | Heavy Metal Concentrations in European Mosses: 2000/2001 Survey显示文摘 | Harry Harmens Alan Buse Patrick Büker David Norris Gina Mills Bronwen Williams Brian Reynolds Trevor W. Ashenden ?ke Rühling Eiliv Steinnes | 2004 | Journal of Atmospheric Chemistry (-)2004，，1： | 1 |
| 16 | Review of methods of odour control 显示文摘 | Brian Mills | 1995 | Filtration & Separation1995，32，2： | 1 |
| 17 | Markedly Elevated Levels of Vascular Endothelial Growth Factor in Malignant Ascites显示文摘 | Brian K. Zebrowski MD Wenbiao Liu MD Karen Ramirez BS Yoshito Akagi MD Gordon B. Mills MD Lee M. Ellis MD | 1999 | Annals of Surgical Oncology1999，，4： | 1 |
| 18 | Quantitative Reverse Transcription–Polymerase Chain Reaction to Study mRNA Decay: Comparison of Endpoint and Real-Time Methods显示文摘 | Thomas D. Schmittgen Brian A. Zakrajsek Alan G. Mills Vladimir Gorn Michael J. Singer Michael W. Reed | 2000 | Analytical Biochemistry2000，，2： | 1 |
| 19 | The role of commodity prices in formulating monetary policy显示文摘 | Brian J Cody Leonard O Mills | 1991 | The Review of Economics and Statistics1991，73，2： | 1 |
| 20 | Assessment of lightning-related fatality and injury risk in Canada 显示文摘 | Brian Mills Dan Unrau Carla Parkinson | 2008 | Nat Hazards2008，，47： | 1 |
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