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89篇 您的检索式:作者名="Brindle M"
    题名 作者 年代 出处 被引量
1Gastrointestinal and liver disease in patients with schizophrenia:A narrative review显示文摘Schizophrenia is a severe mental illness which can have a devastating impact onan individual’s quality of life. Comorbidities are high amongst patients and lifeexpectancy is approximately 15 years less than the general population. Despite thewell-known increased mortality, little is known about the impact of gastrointestinaland liver disease on patients with schizophrenia. We aimed to reviewthe literature and to make recommendations regarding future care. Literaturesearches were performed on PubMed to identify studies related to gastrointestinaland liver disease in patients with schizophrenia. High rates of chronic liverdisease were reported, with Non-Alcoholic Fatty Liver Disease being of particularconcern;antipsychotics and metabolic syndrome were contributing factors. Ratesof acute liver failure were low but have been associated with antipsychotic useand paracetamol overdose. Coeliac disease has historically been linked to schizophrenia;however, recent research suggests that a causal link is yet to be proven.Evidence is emerging regarding the relationships between schizophrenia andpeptic ulcer disease, inflammatory bowel disease and irritable bowel syndrome;clinical vigilance regarding these conditions should be high. Patients with schizophreniapoorly engage with bowel cancer screening programmes, leading to latediagnosis and increased mortality. Clozapine induced constipation is a significantissue for many patients and requires close monitoring. There is a significantburden of gastrointestinal and liver disease amongst patients with schizophrenia.Better levels of support from all members of the medical team are essential toensure that appropriate, timely care is provided.Rebecca K Grant William M Brindle Mhairi C Donnelly Pauline M McConville Thomas G Stroud Lorenzo Bandieri John N Plevris 2022World Journal of Gastroenterology2022,28,38:2
2Surgical treatment of aortic hypoplasia in infants and children with biventricular hearts显示文摘 Van Arsdell GS Brindle M 1999Ann Thorac Surg1999,68,6:1
3Mitochondrial citrate synthase is immobilized in vivo显示文摘Haggie P M Brindle K M 1999J Biol Chem1999,274,7:1
4Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension显示文摘BRINDLE J T NICHOLSON J K SCHOFIELD P M 2003Analyst2003,128,1:1
5Estimation of the intracellular free ADP concentration by 19F NMR studies of fluorine-labeled yeast phosphoglycerate kinase in vivo显示文摘Williams S P Fulton A M Brindle K M 1993Biochemistry1993,32,18:1
619F NMR measurements of the rotational mobility of proteins in vivo 显示文摘Williams S P Haggie P M Brindle K M 1997BiophysJ1997,72,1:1
7Pi- lot plant treatment of a high strength brewery wastewater using a membrane aeration bioreactor 显示文摘BRINDLE K STEPHENSON T SEMMENS M J 1999Water Environment Research1999,71,6:1
8Vascular endothelial growth factor and angiopoietins in neurovascular regeneration and protection following stroke 显示文摘Hansen T M Moss A J Brindle N P 2008Curr Neurovasc Res2008,5,4:1
9The significance and mechanism of mitochondrial proton conductance显示文摘BRAND M D BRINDLE K M BUCKINGHAM J A 1999Int J Ober Relat Metab Disord1999,23,6:1
10Ethanol locks to prevent cath- eter- related bloodstream infections in parenteral nutrition:a meta - analysis显示文摘O1 iveira C Nasr A Brindle M 2012Pediatrics2012,129,:1
11Application of orthogonal signal correction to minimise the effects of physical and biological variation in high resolution 1H NMR spectra of biofluids显示文摘BECKWITH-HALL B M BRINDLE JT BARTON R H 2002Analyst2002,127,10:1
12Liraglutide,a once-daily human GLP-1 analogue,added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes(LEAD-1 SU)显示文摘Mane M Shaw J Brindle M 2009Diabet Med2009,26,3:1
13Small evidence for small incisions : pediatric laparoseopy and the need for more rigorous evaluation of novel surgical therapies 显示文摘Rangel S J Henry MC Brindle M 2003J Pediatr Surg2003,38,:1
14Vascular endothelial growth factor and angiopoietins in neurovascular regeneration and protection following stroke显示文摘HANSEN T M MOSS A J BRINDLE N P 2008Curr Neurovasc Res2008,5,4:1
15Application of ehemometrics to 1H-NMR soectroscopie data to investigate a relationship between human serummetabolic profiles and hypertension 显示文摘Brindle J T Nicholson J K Sehofield P M el al 2003Analyst2003,128,1:1
16Assessment of antiangiogenic and antivascular therapeutics using MRI: recommendations for appropriate methodology for clinical trials 显示文摘Leach M O Brindle KM Evelhoch JL 2003Brit J Radiol2003,76,1:1
17Vascular endothelial growth factor and angiopoietins in neurovascular regeneration and protection following stroke显示文摘Hansen T M Moss A J Brindle N P 2008Curr Neurovasc Res2008,5,:1
1819 F NMR measurements of the rotational mobility of proteins in vivo 显示文摘Williams S P Haggie P M Brindle K M 1997BiophysJ1997,72,1:1
19Membrane aeration bioreactors for wastewater treatment: completely mixed and plug-flow operation 显示文摘Pankhania M Brindle K Stephenson T 1999Chemical Engineering Journal1999,73,2:1
20Influence of stirring-induced mixing on cell proliferation and extraeellular matrix deposition in meniscal cartilage constructs based on polyethylene terephthalate seaffolds显示文摘NEVES A A MEDCALF N BRINDLE K M 2005Biomaterials2005,26,23:1
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