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10篇 您的检索式:作者名="Bruce Beutler"
    题名 作者 年代 出处 被引量
1Prion-like behavior of MAVS in RIG-I signaling显示文摘Eva Marie Y Moresco Diantha La Vine Bruce Beutler 2011Cell Research2011,21,12:3
2Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression显示文摘Motoyuki Otsuka Qing Jing Philippe Georgel Liguo New Jianming Chen Johann Mols Young Jun Kang Zhengfan Jiang Xin Du Ryan Cook Subash C. Das Asit K. Pattnaik Bruce Beutler Jiahuai Han 2007Immunity2007,,1:2
3Emerging roles of spliceosome in cancer and immunity显示文摘Precursor messenger RNA(pre-mRNA)splicing is cat-alyzed by an intricate ribonucleoprotein complex called the spliceosome.Although the spliceosome is consid-ered to be general cell'housekeeping'machinery,mutations in core components of the spliceosome fre-quently correlate with cell-or tissue-specific pheno-types and diseases.In this review,we expound the links between spliceosome mutations,aberrant splicing,and human cancers.Remarkably,spliceosome-targeted therapios(STTs)have become efficient anti-cancer strategies for cancer patients with splicing defects.We also highlight the links between spliceosome and immune signaling.Recent studies have shown that some spliceosome gene mutations can result in immune dysregulation and notable phenotypes due to mis-splicing of immune-related genes.Furthermore,several core spliceosome components harbor splicing-inde-pendent immune functions within the cell,expanding the functional repertoire of these diverse proteins.Hui Yang Bruce Beutler Duanwu Zhang 2022Protein & Cell2022,13,8:1
4Cachectin/tumor necrosis factor: An endogenous mediator of shock and inflammation显示文摘Bruce Beutler Anthony Cerami 1986Immunologic Research1986,,4:1
5TYPE I INTERFERONS (&agr;/&bgr;) IN IMMUNITY AND AUTOIMMUNITY显示文摘Argyrios N. Theofilopoulos Roberto Baccala Bruce Beutler Dwight H. Kono 2005Annual Review of Immunology2005,,:1
6Toll-like recep-tors显示文摘Eva Marie Y Diantha LaVine Bruce Beutler 2011Curr Biol2011,21,13:1
7Innate immunity: an overview显示文摘Bruce Beutler 2003Molecular Immunology2003,,12:1
8Hypersusceptibility to Vesicular Stomatitis Virus Infection in Dicer1-Deficient Mice Is Due to Impaired miR24 and miR93 Expression显示文摘Motoyuki Otsuka Qing Jing Philippe Georgel Liguo New Jianming Chen Johann Mols Young Jun Kang Zhengfan Jiang Xin Du Ryan Cook Subash C. Das Asit K. Pattnaik Bruce Beutler Jiahuai Han 2007Immunity2007,,1:1
9Innate immunity: an overview显示文摘Bruce Beutler 2003Molecular Immunology2003,,12:1
10Genetic and Physical Mapping of the Lps Locus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region显示文摘Alexander Poltorak Irina Smirnova Xiaolong He Mu-Ya Liu Christophe Van Huffel Dale Birdwell Erica Alejos Maria Silva Xin Du Patricia Thompson Edward K.L. Chan Jessica Ledesma Bruce Roe Sandra Clifton Stefanie N. Vogel Bruce Beutler 1998Blood Cells Molecules and Diseases1998,,3:1
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