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| 1 | 基于布拉格光栅传感器的桥墩基础冲刷动态监测试验显示文摘为长期有效监测桥墩基础冲刷作用,基于露出河床的布拉格光栅传感器(FBG传感器)的不同相对位置以及对水流力和结构弯曲的波长变化,提出了一种新的桥墩冲刷动态监测方法;详细介绍了其工作原理,并给出基于该工作原理的监测设计方案,同时介绍了监测设备的制作步骤和设备保护措施设计;按照所提出的监测原理以及监测设备,采用足尺试验模型于实验室水槽中进行基础冲刷模拟试验,模拟了监测冲刷和冲刷回填全过程。结果表明:通过对2次典型试验工况结果的数据分析,证明FBG传感器可实现长期实时监测桥墩冲刷发展和冲刷后河床回填的全过程,为今后实际工程中的桥墩基础冲刷长期实时监测提供理论依据;该监测设备耐久性高,数据准确稳定,不受外界因素(如极端天气)干扰,具备良好的野外应用可行性与优越性。 | 熊文 CAI C S 叶见曙 | 2014 | 中国公路学报2014，27，5： | 12 |
| 2 | 部分地锚斜拉桥经济性能分析显示文摘将部分地锚斜拉桥分为拉索、主塔、主梁、锚碇、基础等五部分,分别推导了其材料用量计算公式,引入材料单价系数,得到了全桥总造价和单位桥面面积造价.据此开展了该桥型经济性能参数研究,得到了主要结构参数的最优取值,即地锚与中跨跨径之比为0.3~0.4,边中跨比为0.40~0.45,塔跨比为0.15~0.20.对比结果表明,随锚碇处地质条件不同,在主跨跨径超过800~1600 m后,部分地锚斜拉桥的经济性能优于全自锚斜拉桥. | 孙斌 肖汝诚 CAI C S | 2013 | 同济大学学报(自然科学版)2013，41，10： | 10 |
| 3 | DYNAMIC VARIATIONS OF WATER QUALITY IN TAIHU LAKE AND MULTIVARIATE ANALYSIS OF ITS INFLUENTIAL FACTORS显示文摘Dynamic variation of water quality in Meiliang Bay and part of West Taihu Lake has been analysed based on data from 1991 to 1992. Principal Component Analysis is used to reveal the mutual relationships of various factors. It is shown that there existis an obvious spatial and temporal variation in the main factors of water quality. Annual values of TP, CON, TN, Chl-a and conductivity decrease evidently from inner Meiliang Bay to the outer from north to south. TP and TN fluctuate seasonally with much higher value in winter. This is particularly true for the mouth of Liangxi River. In addition, the Chl-1 has a synchronous variation with water temperature, although being lagged a little, and closely relates to TP and TN. Finally, the results from Principal Component Analysis show that TP, TN, SS (or SD), water temperature and Chl-a are the most influential factors to water qualuty in this area, and both suspensions and algae can contribute to transparency to Taihu Lake. | Cai Qiming Gao Xiyun Chen Yuwei Ma Shengwei Nanjing Institute of Geography and Limnology, CAS, Nanjing 210008 People’s Republic of ChinaMartin Dokulil Institute of Limnology, Austria | 1997 | Journal of Geographical Sciences1997，7，3： | 9 |
| 4 | Elucidation of the ‘Honeycrisp’ pedigree through haplotype analysis with a multi-family integrated SNP linkage map and a large apple (Malus×domestica) pedigree-connected SNP data set显示文摘The apple(Malus×domestica)cultivar Honeycrisp has become important economically and as a breeding parent.An earlier study with SSR markers indicated the original recorded pedigree of‘Honeycrisp’was incorrect and‘Keepsake’was identified as one putative parent,the other being unknown.The objective of this study was to verify‘Keepsake’as a parent and identify and genetically describe the unknown parent and its grandparents.A multi-family based dense and high-quality integrated SNP map was created using the apple 8 K Illumina Infinium SNP array.This map was used alongside a large pedigree-connected data set from the RosBREED project to build extended SNP haplotypes and to identify pedigree relationships.‘Keepsake’was verified as one parent of‘Honeycrisp’and‘Duchess of Oldenburg’and‘Golden Delicious’were identified as grandparents through the unknown parent.Following this finding,siblings of‘Honeycrisp’were identified using the SNP data.Breeding records from several of these siblings suggested that the previously unreported parent is a University of Minnesota selection,MN1627.This selection is no longer available,but now is genetically described through imputed SNP haplotypes.We also present the mosaic grandparental composition of‘Honeycrisp’for each of its 17 chromosome pairs.This new pedigree and genetic information will be useful in future pedigree-based genetic studies to connect‘Honeycrisp’with other cultivars used widely in apple breeding programs.The created SNP linkage map will benefit future research using the data from the Illumina apple 8 and 20 K and Affymetrix 480 K SNP arrays. | Nicholas P Howard Eric van de Weg David S Bedford Cameron P Peace Stijn Vanderzande Matthew D Clark Soon Li Teh Lichun Cai James J Luby | 2017 | Horticulture Research2017，4，1： | 9 |
| 5 | Endoscopic sphincterotomy associated cholangitis in patients receiving proximal biliary self-expanding metal stents显示文摘BACKGROUND: Endoscopic biliary stent placement during the procedure of endoscopic retrograde cholangiopancreatography (ERCP) is preferred to provide biliary drainage for unresectable malignant biliary obstruction. There is considerable controversy over the use of endoscopic sphincterotomy (ES) prior to stent placement. This study aimed to determine whether ES before intraductal self-expanding metal stent (SEMS) placement affects the clinical outcome and complications in patients with proximal malignant obstructive biliary diseases. METHODS: In a prospective randomized controlled trial, 82 patients with inoperable malignant biliary strictures were randomly assigned to biliary stenting groups with or without ES. Resolution of jaundice and the incidence of complications including acute cholangitis, pancreatitis and stent occlusion within 6 months were evaluated. RESULTS: SEMSs were successfully deployed in all patients, resulting in clinical and biochemical improvement of obstructive symptoms in both groups. The incidence of cholangitis was higher in the ES group than in the non-ES group (58.5% vs 31.7%, P=0.015). The interval between stent placement and the first acute cholangitis was much shorter in the ES group than in the non-ES group (P=0.024). The use of ES increased the incidence of cholangitis (P=0.004, risk ratio, 8.196). The rate of post-ERCP pancreatitis after stent placement was greater in the non-ES group than in the ES group (31.7% vs 9.8%, P=0.014). No significant differences were found in the rate of restenosis and the mortality rate between the two groups.CONCLUSIONS: ES prior to intraductal SEMS placement was associated with an increased incidence of acute cholangitis. ES should be carefully evaluated prior to its use in patients with proximal malignant obstructive biliary diseases. | Hui Zhou, Lei Li, Feng Zhu, Sheng-Zheng Luo, Xiao-Bo Cai,Xin-Jian Wan Department of Gastroenterology, Shanghai First People’s Hospital, Shanghai Jiaotong University, Shanghai 200080, China | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，6： | 8 |
| 6 | Germline mutation analysis of hPMS2 gene in Chinese families with hereditary nonpolyposis colorectal cancer显示文摘AIM: To study the germline mutation of hPMS2 gene in 26 unrelated Chinese hereditary nonpolyposis colorectal cancer (HNPCC) probands and to fulfill the screening strategy for HNPCC in Chinese. METHODS: Genomic DNA was extracted from the peripheral blood. To avoid the interference of pseudogene in detection of the remaining 11 exons (exon 1-5, 9, 11-15), long-range polymerase chain reaction (PCR) was conducted to amplify the complete coding region of hPMS2 gene firstly. Then 1/8 of the PCR productswere used as template to amplify the individual exon respectively and DNA sequencing was done. Direct DNA sequencing of the conventional PCR products of exon 6, 7, 8 and 10 of hPMS2 gene was performed. The same analysis was made in 130 healthy persons without family histories of HNPCC to further investigate the pathological effects of the detected missense mutation. RESULTS: One HNPCC proband fulf illed Bethesda guidelines and was found to carry the germline mutation of hPMS2 gene, which has not been reported in Chinese HNPCC families. It was a missense mutation at c.1532C>T of exon 11. It was detected in three controls as well with an occurrence rate of 2.3% (3/130). Since it could not be found in the PMS2-single nucleotide polymorphism (SNP) database, this missense mutation is a new SNP unreported up to date. Meanwhile, 260 reported SNPs of hPMS2 gene were detected in the 26 HNPCC probands. The 2nd and 5th exons were probably the hot SNP regions of hPMS2 gene in Chinese HNPCC families involving 53.1% of all reported SNP. CONCLUSION: The germline mutation of hPMS2 gene may be rare in Chinese HNPCC families. The 2nd and 5th exons are hot SNP regions of hPMS2 gene. | Xia Sheng, Xiao-Yan Zhou, Xiang Du, Tai-Ming Zhang, WeiQi Sheng, Da-Ren Shi, Department of Pathology, Shanghai Cancer Center, Fudan University, Shanghai 200032, China Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China Heng-Hua Zhou, Department of Pathology, Shanghai Ninth People’s Hospital Affi liated to Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China San-Jun Cai, Department of Abdominal Surgery, Cancer Center, Fudan University, Shanghai 200032, China | 2010 | World Journal of Gastroenterology2010，16，30： | 6 |
| 7 | ECOLOGICAL AND SOCIO-ECONOMIC REHABILITATION IN THE KARST OF SOUTHWEST CHINA显示文摘The Karst of Southwest China is a typical representative of poverty stricken region with impoverishment-degradation spiral. To essentially break away from this vicious circle, the local ecology, economy and society should be rehabilitated, and hence to strengthen the self-development capacity building of the localities. Two considerations are stressed in this article: (1) Poverty alleviation is a system project with great complexities. Any single approach is difficult to success and integrated measures should be taken. (2) Some typical and feasible areas should be selected to demonstrate the project of poverty alleviation and ecological, socio-economic reconstruction. Then, they can be used as a model to promote the sustainable development of the whole region. Based upon these ideals, a project entitled “Reversal of Impoverishment-Degradation Spiral in the Karst of Southwest China' was proposed and has been listed in 《Priority Programme for China’s Agenda 21》. | Cai Yunlong Department of Geography, Peking University, Beijing 100871 People’s Republic of China | 1997 | Journal of Geographical Sciences1997，7，2： | 5 |
| 8 | 高墩连续桥在移动车载作用下的横向振动分析显示文摘将轮胎与路面之间的面接触引入车-桥耦合模型基础上,进一步考虑车辆的横向自由度,提出一种新的车辆模型研究移动车载作用下桥梁的横向振动。将车辆轮胎模拟成一个三维弹簧模型,轮胎与地面的接触面模拟成长方形,通过接触面间的位移协调条件和力相互作用建立车-桥耦合振动方程。考虑影响接触面间横向力大小的三种重要参数如:滑移角、侧偏角、轮胎'S'形运动对耦合系统的影响;并与炉坪大桥实测数据比较,验证该方法的正确性,并分析接触面积、车速等对横向振动的影响。 | 殷新锋 刘扬 Cai C S | 2013 | 振动与冲击2013，32，3： | 4 |
| 9 | Mesozoic giant fleas from northeastern China (Siphonaptera):Taxonomy and implications for palaeodiversity显示文摘The recently discovered definite giant fleas from the Middle Jurassic Daohugou fauna and the Early Cretaceous Jehol fauna of northeastern China represent significant evidence for understanding ectoparasitism in the Mesozoic as well as the evolution of these giant blood feeders with their putative hosts (i.e. hairy or feathered vertebrates). On the basis of seven well-preserved specimens from Daohugou and Huangbanjigou we analyse the systematic classification of these primitive fleas, establishing two new genera and three new species as Pseudopulex wangi sp. nov., Hadropsylla sinica gen. et sp. nov., and Tyrannopsylla beipiaoensis gen. et sp. nov. All of them are assigned to the extinct siphonapteran family Pseudopulicidae, while the Early Cretaceous genus Tarwinia is transferred to Tarwiniidae fam. nov. The basal morphological disparities of Siphonaptera in the Mesozoic are evidenced by the occurrence of at least three distinct groups (pseudopulicids, tarwiniids, and saurophthirids). These disparate morphologies likely indicate adaptations to different hosts. | HUANG DiYing ENGEL Michael S CAI ChenYang NEL André | 2013 | Chinese Science Bulletin2013，58，14： | 4 |
| 10 | Adjunctive aripiprazole for antipsychotic-related hyperprolactinaemia in patients with first-episode schizophrenia:a metaanalysis显示文摘Background Hyperprolactinaemia is a common antipsychotic(AP)-induced adverse effect,particularly in female patients.Aims This meta-analysis examined the efficacy and safety of adjunctive aripiprazole in preventing AP-related hyperprolactinaemia in patients with first-episode schizophrenia.Methods PubMed,PsycINFO,EMBASE,Cochrane Library,WanFang and China Journal Net databases were searched to identify eligible randomised controlled trials(RCTs).Primary outcomes were the reductions of serum prolactin level and prolactin-related symptoms.Data were independently extracted by two reviewers and analysed using RevMan(V.5.3).Weighted/standardised mean differences(WMDs/SMDs)±95%Cis were reported.Results In the five RCTs(n=400),the adjunctive aripiprazole(n=197)and the control groups(n=203)with a mean of 11.2 weeks of treatment duration were compared.The aripiprazole group had a significantly lower endpoint serum prolactin level in all patients(five RCTs,n=385;WMD:-50.43 ng/mL(95%Cl:-75.05 to-25.81),p<0.00001;l2=99%),female patients(two RCTs,n=186;WMD:-22.58 ng/mL(95%Cl:-25.67 to-19.49),p<0.00001;l2=0%)and male patients(two RCTs,n=127;WMD:-68.80 ng/mL(95%Cl:-100.11 to-37.49),p<0.0001).In the sensitivity analysis for the endpoint serum prolactin level in all patients,the findings remained significant(p<0.00001;l2=96%).The aripiprazole group was s叩erior to the control group in improving negative symptoms as assessed by the Positive and Negative Syndrome Scale(three RCTs,n=213;SMD:-0.51(95%Cl:-0.79 to-0.24),p=0.0002;l2=0%).Adverse effects and discontinuation rates were similar between the two groups.Conclusions Adjunctive aripiprazole appears to be associated with reduced AP-induced hyperprolactinaemia and improved prolactin-related symptoms in first-episode schizophrenia.Further studies with large sample sizes are needed to confirm these findings. | Wei Zheng Dong-Bin Cai Xin-Hu Yang Wei Zheng Gabor S Ungvari Chee H Ng Zhan-Ming Shi Mei-Ling Hu Yu-Ping Ning Yu-Tao Xiang | 2019 | General Psychiatry2019，32，5： | 4 |
| 11 | 基于力学与造价的CFRP-钢组合拉索斜拉桥设计理论显示文摘针对1 400~2 800m主跨斜拉桥整体刚度不足的问题,提出一种新型结构方案——碳纤维增强塑料(CFRP)-钢组合拉索斜拉桥。该方案将CFRP斜拉索与传统钢斜拉索同时应用于斜拉桥中,组合2种材料高强轻质及弹性模量高的优点,以达到提高斜拉桥整体刚度的设计目的。通过基于力学与造价的参数分析提出该组合拉索斜拉桥的3种设计原则:等安全系数等效刚度最优、等安全系数等效刚度性价比最优、等造价等效刚度最优,并分别给出详细的设计步骤及设计用图。最后,进行了多种方案1 400m主跨斜拉桥试设计。结果表明:CFRP-钢组合拉索斜拉桥在力学与经济性方面均具有一定优势,其工程应用具有可行性,是主跨为1 400~2 800m斜拉桥的优选方案之一。 | 熊文 肖汝诚 CAI C S 叶见曙 | 2012 | 中国公路学报2012，25，4： | 4 |
| 12 | STRUCTURES OF SYSTEMS WITH EXPONENTIAL LIFE DISTRIBUTIONS显示文摘Abstract. Structures of monotone systems and cold standby systems | CAI JUN WU YANHONG Department of Mathematics, Teacher’s College of Yanzhou University Yangzhou 225002 Current address: Department of Mathematics and Statistics, Concordia University, Montreal, Quebec, Canada. Department of Mathematical Sciences,University of Alberta, Edmonton, Alberta, T6G 2G1, Canada. | 1996 | Applied Mathematics(A Journal of Chinese Universities)1996，11，1： | 3 |
| 13 | Adjunctive Peony-Glycyrrhiza decoction for antipsychotic-induced hyperprolactinaemia:a meta-analysis of randomised controlled trials显示文摘Background Hyperprolactinaemia is a common adverse effect of antipsychotics(APs). The results of PeonyGlycyrrhiza decoction(PGD) as a potentially useful adjunctive treatment for hyperprolactinaemia are inconsistent.Aim This meta-analysis of randomised controlled trials(RCTs) examined the efficacy and safety of adjunctive PGD therapy for AP-induced hyperprolactinaemia.Methods English(PubMed, Embase, Cochrane Library,PsycINFO) and Chinese(Chinese National Knowledge Infrastructure, Wanfang Data) databases were systematically searched up to 10 June 2018. The inclusion criteria were based on PIC0 S一/^rticipants: adult patients with schizophrenia; Aitervention: PGD plus APs; Cbmparison: APs plus placebo or AP monotherapy;(Xjtcomes: efficacy and safety; Study design: RCTs. The weighted mean difference(WMD) and risk ratio(RR) along with their 95% CIs were calculated using Review Manager(RevMan) V.5.3 software.Results Five RCTs(n=450) were included and analysed.Two RCTs(n=140) were double-blind and four RCTs(n=409) reported ‘random' assignment with specific description. The PGD group showed a significantly lower serum prolactin level at endpoint than the control group(n=380, WMD:-32.69 ng/mL(95% Cl-41.66 to 23.72),/X0.00001, ^=97%). Similarly, the superiority of PGD over the control groups was also found in the improvement of hyperprolactinaemia-related symptoms. No difference was found in the improvement of psychiatric symptoms assessed by the Positive and Negative Syndrome Scale(n=403,WMD:-0.62(95% Cl-2.38 to 1.15), p=0.49, ^=0%). There were similar rates of all-cause discontinuation(n=330, RR0.93(95% Ci 0.63 to 1.37),/t=0.71, ^=0%) and adverse drug reactions between the two groups. According to the Grading of Recommendations Assessment, Development and Evaluation approach, the level of evidence of primary and secondary outcomes ranged from ‘very low'(14.3%),‘low'(42.8%),‘moderate'(14.3%),to ‘high,(28.6%>.Conclusions Current evidence supports the adjunctive use of PGD to suppress elevated prolactin and improve prolactininduced symptoms without significant adverse events in adult patients with AP-induced hyperprolactinaemia. Highquality RCTs with longer duration are needed to confirm these findings.Trial registration number 42016037017. | Wei Zheng Dong-Bin Cai Hai-Yan Li Yu-Jie Wu Chee H Ng Gabor S Ungvari Shan-Shan Xie Zhan-Ming Shi Xiao-Min Zhu Yu-Ping Ning Yu-Tao Xiang | 2018 | General Psychiatry2018，31，4： | 3 |
| 14 | Monitoring Greenhouses Gases over China Using Space-Based Observations Monitoring Greenhouses Gases over China Using Space-Based Observations显示文摘The atmospheric carbon dioxide(CO 2)concentration has increased to more than 405 parts per million(ppm.1 ppm=10-6 m/s 2)in 2017 due to human activities such as deforestation,land-use change and burning of fossil fuels.Although there is broad scientific consensus on the damaging consequences of the change in climate associated with increasing concentrations of greenhouse gases,fossil CO 2 emissions have continued to increase in recent years mainly from rapidly developing economies and China is now the largest emitter of CO 2 generating about 30%of all emissions globally.To allow more reliable forecast of the future state of the carbon cycle and to support the efforts for mitigation greenhouse gas emissions,a better understanding of the global and regional carbon budget is needed.Space-based measurements of CO 2 can provide the necessary observations with dense coverage and sampling to provide improved constrains on of carbon fluxes and emissions.The Chinese Global Carbon Dioxide Monitoring Scientific Experimental Satellite(TanSat)was established by the National High Technology Research and Development Program of China with the main objective of monitoring atmospheric CO 2 and CO 2 fluxes at the regional and global scale.TanSat has been successfully launched in December 2016 and as part of the Dragon programme of ESA and the Ministry of Science and Technology(MOST),a team of researchers from Europe(UK and Finland)and China has evaluated early TanSat data and contrast it against data from the GOSAT mission and models.In this manuscript,we report on retrieval intercomparisons of TanSat data using two different retrieval algorithms,on validation efforts for the Eastern Asia region using GOSAT CO 2 data and first assessments of TanSat and GOSAT CO 2 data against model calculations using the GEOS-Chem model. | Hartmut BOESCH Yi LIU Paul I PALMER Johanna TAMMINEN Jasdeep S ANAND Zhaonan CAI Ke CHE Huilin CHEN Xi CHEN Liang FENG Janne HAKKARAINEN Pauli HEIKKINEN Nikoleta KALAITZI Rigel KIVI Robert PARKER Peter SOMKUTI Jing WANG Alex WEBB Dongxu YANG Lu YAO You YI | 2020 | Journal of Geodesy and Geoinformation Science2020，3，4： | 2 |
| 15 | Clinicopathogenic studies of acute diarrhea in children显示文摘ClinicopathogenicstudiesofacutediarheainchildrenCAILiMin,ZHANGChang,CHENHe,JIANGWeiPingandMAOWenXiangDepartmentofInfectiou... | CAI Li Min, ZHANG Chang, CHEN He, JIANG Wei Ping and MAO Wen Xiang Department of Infectious Diseases, The First People′s Municipal Hospital of Wenling, Wenling City 317500, Zhejiang Province, China | 1997 | World Journal of Gastroenterology1997，3，3： | 2 |
| 16 | Design of feedback control laws for switching regulators based on the bilinear large signal model显示文摘 | Chen F Cai X S | 1990 | IEEE Transactions on Power Electronics1990，5，2： | 2 |
| 17 | Dynamic analysis of a flexible hub-beam system with tip mass显示文摘 | Cai G P Hong J Z Yang S X | 2005 | Mechanics Research Communications2005，32，2： | 1 |
| 18 | Significant correlation between micrometastasis in the lymph nodes and reduced expression of E-cadherin in early gastric cancer 显示文摘 | Cai J Ikeguchi M Tsujitani S | 2001 | Gastric Cancer2001，4，2： | 1 |
| 19 | Thermochemical sulphate reduction and the generation of hydrogen sulphide and thiols(mercaptans)in Triassic carbonate reservoirs from the Sichuan Basin,China显示文摘 | CAI CHUNFANG WORDEN R H BOTTRELL S H | 2003 | Chemieal Geology2003，202，12： | 1 |
| 20 | Oral N-acetylcysteine attenuates pulmonary emphysema and alveolar septal cell apoptosis in smoking-induced COPD in rats 显示文摘 | Cai S Chen P Zhang C | 2009 | Respirology2009，14，3： | 1 |
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