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| 1 | Reliability of ultrasound ovarian-adnexal reporting and data system amongst less experienced readers before and after training显示文摘BACKGROUND The 2018 ovarian-adnexal reporting and data system(O-RADS)guidelines are aimed at providing a system for consistent reports and risk stratification for ovarian lesions found on ultrasound.It provides key characteristics and findings for lesions,a lexicon of descriptors to communicate findings,and risk characterization and associated follow-up recommendation guidelines.However,the ORADS guidelines have not been validated in North American institutions or amongst less experienced readers.AIM To evaluate the diagnostic accuracy and inter-reader reliability of ultrasound ORADS risk stratification amongst less experienced readers in a North American institution with and without pre-test training.METHODS A single-center retrospective study was performed using 100 ovarian/adnexal lesions of varying O-RADS scores.Of these cases,50 were allotted to a training cohort and 50 to a testing cohort via a non-randomized group selection process in order to approximately equal distribution of O-RADS categories both within and between groups.Reference standard O-RADS scores were established through consensus of three fellowship-trained body imaging radiologists.Three PGY-4 residents were independently evaluated for diagnostic accuracy and inter-reader reliability with and without pre-test O-RADS training.Sensitivity,specificity,positive predictive value,negative predictive value(NPV),and area under the curve(AUC)were used to measure accuracy.Fleiss kappa and weighted quadratic(pairwise)kappa values were used to measure inter-reader reliability.Statistical significance was P<0.05.RESULTS Mean patient age was 40±16 years with lesions ranging from 1.2 to 22.5 cm.Readers demonstrated excellent specificities(85%-100%pre-training and 91%-100%post-training)and NPVs(89%-100%pre-training and 91-100%post-training)across the O-RADS categories.Sensitivities were variable(55%-100%pre-training and 64%-100%post-training)with malignant ORADS 4 and 5 Lesions pre-training and post-training AUC values of 0.87-0.95 and 0.94-098,respectively(P<0.001).Nineteen of 22(86%)misclassified cases in pre-training were related to mischaracterization of dermoid features or wall/septation morphology.Fifteen of 17(88%)of posttraining misclassified cases were related to one of these two errors.Fleiss kappa inter-reader reliability was‘good’and pairwise inter-reader reliability was‘very good’with pre-training and post-training assessment(k=0.76 and 0.77;and k=0.77-0.87 and 0.85-0.89,respectively).CONCLUSION Less experienced readers in North America achieved excellent specificities and AUC values with very good pairwise inter-reader reliability.They may be subject to misclassification of potentially malignant lesions,and specific training around dermoid features and smooth vs irregular inner wall/septation morphology may improve sensitivity. | Prayash Katlariwala Mitchell P Wilson Yeli Pi Baljot S Chahal Roger Croutze Deelan Patel Vimal Patel Gavin Low | 2022 | World Journal of Radiology2022，14，9： | 2 |
| 2 | A comparison of direct endoscopic necrosectomy with transmural endoscopic drainage for the treatment of walled-off pancreatic necrosis显示文摘 | Gardner TB Chahal P Papachristou GI | 2009 | Gastrointest Endosc2009，69，6： | 1 |
| 3 | Does subclinical atherosclerosis burden identify the increased risk of cardiovascular disease mortality among United Kingdom Indian Asians? A population study显示文摘 | CHAHAL N S LIM T K JAIN P | 2011 | Am Heart J2011，162，3： | 1 |
| 4 | Characterization of aryl hydrocarbon receptor interacting protein(AIP)mutations in familial isolated pituitary adenoma families显示文摘 | Igreja S Chahal HS King P | 2010 | Hum Mutat2010，31，8： | 1 |
| 5 | Endoscopic palliation of cholangiocarcinoma 显示文摘 | Chahal P Baron TH | 2006 | Curr Opin Gastroen- terol2006，22，5： | 1 |
| 6 | Structural and dielectric spectroscopic studies of polyaniline-poly (methyl methacrylate) composite films显示文摘 | Tomar A K Mahendia S Chahal R P | 2012 | Synth Metals2012，162，9： | 1 |
| 7 | Pancreatic stent prophylaxis of post endoscopic retrograde cholangiopancreatography pancreatitis: spontaneous migration rates and clinical outcomes显示文摘 | CHAHAL P BARON T H PETERSEN B T | 2007 | Minerva Gastroenterol Dietol2007，53，3： | 1 |
| 8 | Short 5Fr vs long 3Fr pancreatic stents in patients at risk for post-endoscopic retrograde cholangiopancreatography pancreatitis显示文摘 | CHAHAL P TARNASKY P R PETERSEN B T | 2009 | Clin Gastroenterol Hepatol2009，7，8： | 1 |
| 9 | Ethnicity-related differences in left ventricular function,structure and geometry:a population study of UK Indian Asian and European white subject显示文摘 | Chahal NS Lim TK Jain P | 2010 | Heart2010，96，6： | 1 |
| 10 | Endoscopic palliation of cholangiocarcinoma显示文摘 | Chahal P Baron TH | 2006 | Curt Opin Gastroenterol2006，22，5： | 1 |
| 11 | New insights into the relationship of left ventricular geometry and left ventricular mass with cardiac function: A population study of hypertensive subjects 显示文摘 | Chahal NS Lira TK Jain P | 2010 | Eur Heart J2010，31，5： | 1 |
| 12 | Endoscopic palliation of cholangiocarcinoma显示文摘 | Chahal P Baron TH | 2006 | Curr Opin Gastroenterol2006，22，5： | 1 |
| 13 | Endoscopic palliation of cholangiocarci- noma显示文摘 | Chahal P Baron TH | 2006 | Curt Opin Gastroenterol2006，22，5： | 1 |
| 14 | Pancreatic stent prophylaxis of post endoscopic retrograde cholangiopancreatography pancreatitis:spontaneous migration rates and clinical outcomes显示文摘 | CHAHAL P BARON TH PETERSEN BT | 2007 | Minerva Gastroenterol Dieto12007，53，3： | 1 |
| 15 | Short 5Fr vs long 3Fr pancreatic stents in patients at risk for post-endoscopic ret- rograde cholangiopancreatography pancreatitis 显示文摘 | CHAHAL P TARNASKY PR PETERSEN BT | 2009 | Clin Gastroenterol Hepatol2009，7，8： | 1 |
| 16 | A novel chimeric lysin shows superiority to mupirocin for skin decolonization of methicillin- resistant and -sensitive Staphylococcus aureus strains显示文摘 | Pastagia M Euler C Chahales P | 2011 | Antimicrob Agents Chemother2011，55，2： | 1 |
| 17 | New insights into the relationship of left ventricular geometry and left ventricular mass with cardiac function: A population study of hypertensive subjects 显示文摘 | Chahal NS Lim TK Jain P | 2010 | Eur Heart J2010，31，5： | 1 |
| 18 | Expandable metal stents for endoscopic bilateral stent-within-stent placement for malignant hilar biliary obstruction显示文摘 | Chahal P Baron TH | 2010 | Gastrointest Endosc2010，71，1： | 1 |
| 19 | An Ontology Based Approach for Finding Semantic Similarity between Web Documents显示文摘 | Chahal P Singh M Kumar S | 2013 | In- ternational Journal of Current Engineering and Technology2013，3，5： | 1 |
| 20 | Potential utility of EUS in the diagnosis and management of intramural gastric abscess显示文摘 | Chahal P Levy MJ | 2008 | gastroenterol hepatol (N Y)2008，4，9： | 1 |
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