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| 1 | Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting显示文摘瞄准:如果与推延的 portasystemic 有关的 T 房间激活通过 RANKL 依赖的小径引起调停骨破折的骨头损失,学习。如果用 rapamycin 的 T 房间抑制将在老鼠免于骨头损失,我们也调查了。方法:推延的 Portasystemic 在男 Sprague-Dawley 老鼠和 rapamycin 被执行 0.1 mg/kg 被管饲法为 15 wk 管理。老鼠收到了 powderized 食物并且补加喂在骨头作文上阻止营养不良的效果。重量获得和生长在推延的动物在外科以后被恢复。在结束,骨头周转和量的骨头组织学的生物化学的参数被估计。T 房间激活,煽动性的 cytokine 生产,和 RANKL 依赖的小径的标记被测量。另外, IGF-1 和性腺机能减退的角色被调查。结果:推延的 Portasystemic 引起了是 RANKL 独立人士的低周转骨质疏松症。包括 IL-1, IL-6 和 TNFalpha,骨头再吞 cytokine 层次没在浆液和 TNFalpha 被增加, RANKL 表示不起来在 PBMC 调整了。推延的 Portasystemic 增加了传播 CD8+T 房间人口。Rapamycin 减少了传播 CD8+T 房间人口,增加了 CD8+CD25+T 规章的房间人口并且改进了骨头周转的所有参数。结论:推延的 portasystemic 引起的骨质疏松症可以被 rapamycin 部分在肝的骨营养不良的老鼠模型改善。 | Schalk W van der Merwe Maria M Conradie Robert Bond Brenda J Olivier Elongo Fritz Martin Nieuwoudt Rhena Delport Tomas Slavik Gert Engelbrecht Del Kahn Enid G Shephard Maritha J Kotze Nico P de Villiers Stephen Hough | 2006 | World Journal of Gastroenterology2006，12，28： | 2 |
| 2 | Effect of statins on bone mineral density and bone histomorphometry in rodents显示文摘 | Maritz F J Conradie M M Hulley P A | 2001 | Arteriosclerosis Thrombosis and Vascular Biology2001，21，10： | 1 |
| 3 | An increase in depressive symptoms after myocardial infarction predicts new cardiac events ir- respective of depressive symptoms before myocardial infarction 显示文摘 | Zuidersma M Ormel J Conradi HJ | 2012 | Psychol Med2012，42，4： | 1 |
| 4 | Radiation dose exposure of computed tomography coronary angiography:comparison of dual-source,16-slice and 64-slice CT显示文摘 | Rixe J Conradi G Rolf A | 2009 | Heart2009，95，16： | 1 |
| 5 | Reduction of pulse-to-pulse interaction using alternative RZ formats in 40Gb/s systems显示文摘 | Cheng K S Conradi J | 2002 | IEEE Photon Technol Lett2002，14，1： | 1 |
| 6 | Sensory and functional meat quality characteristics of pork derived from three halothane genotypes显示文摘 | Moelich E Hoffman L C Conradie P J | 2003 | Meat Science2003，63，3： | 1 |
| 7 | Integrated product and process management in EPOS 显示文摘 | Munch B P Conradi R Larsen J O | 1996 | Integrated Computer - Aided Engineering1996，3，1： | 1 |
| 8 | Long-term exposure to 4-nonylphenol affects sexual differentiation and growth of the amphipod Corophium volutator(Pallas, 1766)显示文摘 | Brown R J M Conradi Depledge M H | 1999 | Sci Total Environ1999，233，： | 1 |
| 9 | Integrated product and process management in EPOS显示文摘 | MUNCH B P CONRADI R LARSEN J O | 1996 | Integrated Computer-Aided Engineering1996，3，1： | 1 |
| 10 | Transapical implantation of a second-generation transcatheter heart valve in patients with noncalcified aortic regurgitation 显示文摘 | Seiffert M Diemert P Koschyk D Schirmer J Conradi L Schnabel R | 2013 | JACC Cardiovasc Interv2013，6，： | 1 |
| 11 | Subnetwork analysis re-veals dynamic featuresof complex (bio) chemical networks 显示文摘 | Conradi C Floekerzi D Raiseh J | 2007 | Proc Natl Acad Sci USA2007，104，19： | 1 |
| 12 | Core characteristics of the competent general practice trainer,a Delphi study 显示文摘 | Boendermaker PM Conradi MH Schuling J | 2003 | Adv Health Sci Educ Theory Pract2003，8，2： | 1 |
| 13 | Prognostic association of depression following myocardial infarction with mortality and cardiovascular events: a meta-analysis of 25 years of research显示文摘 | MEIJER A CONRADI H J BOS E H | 2011 | Gen Hosp Psychiatry2011，33，3： | 1 |
| 14 | Impact of double Rayleigh backscatter noise on digital and analog fiber aystems显示文摘 | WAN P CONRADI J | 1996 | Journal of Lightwave Technology1996，14，13： | 1 |
| 15 | Radiation dose exposure of computed tomography coronary angiography: comparison of dual-source, 16-slice and 64-slice CT 显示文摘 | Rixe J Conradi G Roll A | 2009 | Heart2009，95，： | 1 |
| 16 | The distribution of gains in uniformly multiplying avalanche photodiodes:experimental显示文摘 | | 1972 | IEEE Transactions on Electron Devices1972，19，6： | 1 |
| 17 | Optimal Touch But-ton Size for the Use of Mobile Devices while Walking显示文摘 | Conradi J Busch 0 Alexander T | 2015 | Procedia Manufacturing2015，3，1： | 1 |
| 18 | Neurotuberculosis : a contin- uing clinical challenge 显示文摘 | Mackert BM Conradi J Loddenkemper C | 2008 | Nervenarzt2008，79，2： | 1 |
| 19 | Qualitative assessment of genotoxicity using random amplified olymorphic DNA:Comparison of gcnomic template stability with key fitness parameters in Daphnia magna exposed to benzo(a)pyrene显示文摘 | Conradi M Evenden A J | 1999 | Environmeutal Toxicology and Chemistry1999，18，10： | 1 |
| 20 | Restriction point control of the mammalian cell cycle via the cyclin E/Cdk2:p27 complex 显示文摘 | Conradie R Bruggeman F J Ciliberto A | 2010 | FEBS J2010，277，2： | 1 |
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