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78篇 您的检索式:作者名="CY Luo"
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1Estrogen enhances the functions of CD4^(+)CD25^(+)Foxp3^(+) regulatory T cells that suppress osteoclast differentiation and bone resorption in vitro显示文摘Cross-talk has been shown to occur between the immune system and bone metabolism pathways.In the present study,we investigated the impact of CD4^(+)CD25^(+)Foxp3^(+) regulatory T(Treg)cells on osteoclastogenesis and bone resorption.Treg cells that were isolated and purified from peripheral blood mononuclear cells(PBMCs)of healthy adults inhibited both the differentiation of osteoclasts(OCs)from human embryo bone marrow cells(BMCs)and the pit formation in a dose-dependent manner.In cell cocultures,the production levels of both interleukin-10(IL-10)and transforming growth factor-beta 1(TGF-β1)were proportionally upregulated as the ratio of Treg cells to BMCs was increased,and the inhibition of OC differentiation and bone resorption by Treg cells was completely reversed by anti-IL-10 and anti-TGF-β1 antibodies.Treatment of BMC and Treg cell cocultures with 17β-estradiol(E2)at concentrations between 10^(-7) and 10^(-9) mol/l suppressed OC differentiation and bone resorption more efficiently than it did in cultures of BMCs alone;this enhanced suppression occurred via the stimulation of Treg cell IL-10 and TGF-b1 expression.These data suggest that Treg cells suppress OC differentiation and bone resorption by secreting IL-10 and TGF-β1.E2 enhances the suppressive effects of Treg cells on OC differentiation and bone resorption by stimulating IL-10 and TGF-β1 secretion from these cells.Therefore,Treg cell-derived IL-10 and TGF-b1 are likely involved in the regulation of E2 on bone metabolism and represent potential therapeutic targets for the treatment of postmenopausal osteoporosis(PMO).CY Luo L Wang C Sun DJ Li 2011Cellular & Molecular Immunology2011,8,1:33
2Ge- netic diversity and drug resistance among newly diagnosed and antiretroviral treatment-naive HIV-infected individuals in western Yunnan: a hot area of viral recombination in China 显示文摘Chen M Ma Y Duan S Xing H Yao S Su Y Luo H Yang L Chen H Fu L Qu A Ou CY Jia M Lu L 2012BMC Infect Dis2012,12,:1
3A standardized surgical technique for mastoscopic axillary lymph node dissection 显示文摘Luo CY Zhou YQ Liu H 2005Surg Laparosc Endosc Pereutan Tech2005,15,3:1
4Imaging presentation highly manifested as tuberculosis in a case of spinal melastatie carcinoma显示文摘Zheng CY Liu DX Luo SW 2011Orthopedies2011,34,:1
5Identification of 20 snoRNA-like RNAs from the primitive eukaryote, Giardia /amb//a显示文摘Yang CY Zhou I4 Luo J et ol 2005Biochem Biophys Res Commun2005,328,4:1
6Effect of a single oral dose of rabeprazole on nocturnal acid breakthrough and nocturnal alkaline amplitude显示文摘Luo JY Niu CY Wang XQ 2008World J Gastroenterol2008,10,11:1
7Development of HIV/AIDS vaccine using chimeric gag-envvirus-like particles 显示文摘 LUO L WAINBERG MA 1999Biol Chem1999,380,3:1
8Gastrointestinal dysfunction in a Parkinson's disease rat model and the changes of dopaminergic,nitric oxidergic,and cholinergic neurotransmitters in myenteric plexus显示文摘Zhu HC Zhao J Luo CY 2011J Mol Neurosci2011,29,5:1
9Endoscopic saphenous vein harvest decreases leg wound complication in coronary artery bypass grafting patients显示文摘Kan CD Luo CY Yang YJ 1999J Card Surg1999,14,3:1
10Intravenous leiomyomatosis with intraeardiac extension显示文摘Wu CK Luo JL Yang CY 2009Intern Med2009,48,12:1
11Determination of flavonoids in propolis-rich functional foods by reversed phase high performance liquid chromatography with diode array detection显示文摘Luo CY Zou XL Li YQ 2011Food Chemistry2011,127,:1
12Antimicrobial resistance patterns and serotype distribution of invasive streptococ- cus isolates from children in Taiwan from 1999 to 2004 显示文摘Lin WJ Luo WT Chou CY 2006Diagn microb Infact Dis2006,56,2:1
13Comparison of masto- scopic and conventional axillary lymph node dissection in breast cancer:long-term results from a randomized,multi- center trial显示文摘Luo CY Guo WB Yang J 2012Mayo Clin Proc2012,87,12:1
14In situ reconstruction of septic aortic pseudoaneurysm due to Salmonella or Streptococcus microbial aortitis: long-term follow-up显示文摘Luo CY Ko WC Kan CD 2003J Vasc Surg2003,38,5:1
15Computed tomography and magnetic resonance imaging characteristics of giant pituitary adenomas显示文摘Chang CY Luo CB Teng MM 2000J Formos Med Assoc2000,99,11:1
16A standardized surgical technique for mastoscopic axillary lymph nodedissection 显示文摘Luo CY Zhou YQ Lin H 2005Surg Laparosc Endosc Percutan Tech2005,15,3:1
17Computed tomography and magnetic resonance imaging characteristics of giant pituitary adenomas显示文摘Chang CY Luo CB Teng MM 2000J Formos Med Assoc2000,99,11:1
18Baculovirus as a gene delivery vector for cartilage and bone tissue engineering显示文摘Lin CY Lu CH Luo WY 0,,03:1
19Thrombomodulin is upregulated in cardiomyocytes during cardiac hypertrophy and prevents the progression of contractile dysfunction显示文摘Li YH Chung HC Luo CY 2010Journal of cardiac failure2010,16,12:1
20Warming and grazing increase mineralization of organic P in an alpine meadow ecosystem of Qinghai-Tibet Plateau, China 显示文摘Rui YC Wang YF Chen CR Zhou XQ Wang SP Xu ZH Duan JC Kang XM Lu SB Luo CY 2012Plant Soil2012,357,:1
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