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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Beneficial effects ofgreen tea-a review 显示文摘 | Cabrera C Artacho R Giménez R | 2006 | Journal of the American College ofNutrition2006，25，2： | 1 |
| 3 | Usefulness of anorectal manometry in the neonatal diagnosis of Hirschsprung disease显示文摘 | Nunez R Cabrera R Moreno C | | 0，，01： | 1 |
| 4 | Early hematopoietic recovery after single unit unrelated cord blood transplantation in adults supported by co-infusion of mobilized stem cells from a third party donor显示文摘 | Magro E Regidor C Cabrera R | 2006 | Haematologica2006，91，5： | 1 |
| 5 | Electrochemical and surface analysis study of copper corrosion protection by 1 & hyphen;propanethiol and propyltrimethoxysilane & colon; A comparison with 3 & hyphen; mercaptopropyltrimethoxysilane 显示文摘 | Tremont R Cabrera C R | 2002 | Journal of Applied Electrochemistry2002，32，7： | 1 |
| 6 | Lab-on-a-chip for drug development 显示文摘 | WEIGL B H BARDELL R L CABRERA C R | 2003 | Advanced Drug Delivery Reviews2003，55，3： | 1 |
| 7 | Fungal endophytes and their role in plant protection显示文摘 | Gimenez C Cabrera R Reina M | 2007 | Curt Org Chem2007，11，： | 1 |
| 8 | Beneficial effects ofgreen tea:a review显示文摘 | CABRERA C ARTACHO R GIMENEZ R | 2006 | Journal of the American College of Nutrition2006，25，2： | 1 |
| 9 | Determination of tea components with antioxidant activity显示文摘 | Cabrera C Gimenez R Lopez M C | 2003 | Journal of Agricultural and Food Chemistry2003，51，15： | 1 |
| 10 | Beneficial effects of green tea-a review显示文摘 | Cabrera C Artacho R Gimenez R | 2006 | J Am Coil Nutr2006，25，2： | 1 |
| 11 | Sterentactic radio- surgery and bevacizunmb for recurrent glioblastoma multifnrme 显示文摘 | Cabrera A R Cuneo K C Vredenburgh J J | 2012 | J Nail Compr Cane Netw2012，10，6： | 1 |
| 12 | Determination of tea compo- nents with antioxidant activity 显示文摘 | Cabrera C Gimenez R Lopez MC | 2003 | J Agric Food Chem2003，51，15： | 1 |
| 13 | Exploratory Dijkstra forest based automatic vessel seg- mentation : applications in video indirect ophthalmoscopy (VIO) 显示文摘 | Estrada R Tomasi C Cabrera MT Wallace DK Freedman SF Farsiu S | 2012 | Biomedical Optics Express2012，3，2： | 1 |
| 14 | Oxidation of methanol on platinum, ruthenium and mixed Pt-M metais (M = Ru, Sn) : A theoretical study显示文摘 | ISHIKAWA Y LIAO M S CABRERA C R | 2000 | Surf Sci2000，463，1： | 1 |
| 15 | Beneficial effects of green tea-a review 显示文摘 | Cabrera C Artacho R Gimfinez R | 2006 | J Am Coil Nutr2006，25，2： | 1 |
| 16 | Concurrent stereotae-tic radiosurgery and bevacizumab in recurrent malignant gliomas: a prospective trial 显示文摘 | Cabrera A R Cuneo K C Desjardins A | 2013 | lnt J Radiat Oncol Biol Phys2013，86，5： | 1 |
| 17 | External ultrasonic lipoplasty:an effective method of fat removal and skin shrinkage显示文摘 | CABRERA R C | 2000 | Plast Reeonstr Surg2000，105，2： | 1 |
| 18 | Unrelated umbilical cord blood transplants in adults:early recovery of neutrophils by supportive cotransplantafion of a low number of highly purified peripheral blood CD34^+ cells from an HLA haploidentical donor 显示文摘 | Fernandez MN Regidor C Cabrera R | 2003 | Exp Hematol2003，31，6： | 1 |
| 19 | Training Practices and Organizational Learning Capability : Relationship and Implica- tions 显示文摘 | Gomez P J Lorente J J C Cabrera R V | 2004 | Journal of European Industrial Training2004，28，23： | 1 |
| 20 | Cord blood transplants: early recovery of neutrophils from co-transplant- ed sibling haploidentical progenitor cells and lack of en- graftment of cultured cord blood cells, as ascertained by analysis of DNA polymorphisms显示文摘 | Fernandez MN Regidor C Cabrera R | 2001 | Bone Marrow Transplant2001，28，： | 1 |
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