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| 1 | A prospective analysis of factors that influence weight loss in patients undergoing radiotherapy显示文摘Malnutrition occurs frequently in patients with cancer.Indeed,a variety of nutritional and tumorrelated factors must be taken into account in these patients.Recognizing this relationship,we aimed to prospectively evaluate the risk factors that influence weight loss in patients undergoing radiotherapy with oral nutritional supplementation and dietetic counseling.Weight loss of 74 patients during radiotherapy and 1 month after treatment was analyzed.Parameters such as age,gender,tumor location,tumor stage,Eastern Cooperative Oncology Group performance status(ECOG PS)score,and the use of chemotherapy were analyzed to evaluate their influence on weight loss.All patients underwent oral nutritional supplementation and dietetic counseling.Forty-six(65.7%)patients lost weight,with a mean weight loss of(4.73±3.91)kg,during radiotherapy.At 1 month after treatment,45(66.2%)patients lost weight,presenting a mean weight loss of(4.96±4.04)kg,corresponding to a(6.84±5.24)%net reduction from their baseline weight.Head and neck cancer patients had a mean weight loss of(3.25±5.30)kg,whereas the remaining patients had a mean weight loss of(0.64±2.39)kg(P=0.028)during radiotherapy.In the multivariate analysis,the head and neck tumor location(P=0.005),use of chemotherapy(P=0.011),and ECOG PS score of 2-3(P=0.026)were considered independent risk factors.Nutritional status and parameters,such as tumor location(especially the head and neck),the use of chemotherapy,and the ECOG PS score,should be evaluated before radiotherapy because these factors can influence weight loss during radiotherapy and 1 month after treatment. | Jon Cacicedo Francisco Casquero Lorea Martinez-Indart Olga del Hoyo Alfonso Gomez de Iturriaga Arturo Navarro Pedro Bilbao | 2014 | Chinese Journal of Cancer2014,33,4: | 12 |
| 2 | AMPK, insulin resistance, and the metabolic syndrome显示文摘 | Ruderman Neil B Carling David Prentki Marc Cacicedo Jos? M | 2013 | Journal of Clinical Investigation2013,,7: | 2 |
| 3 | Regulation of growth hormone (GH) gene expression and secretion during pregnancy and lactation in the rat: Role of insulin-like growth fuction-1 ,somatostation , and GH-releasing hormone 显示文摘 | ESCALADA J CACICEDO L | 1997 | Endocrindogy1997,138,8: | 1 |
| 4 | Growth hormone action on proliferation and differentiation of cerebral cortical cells from fetal rat 显示文摘 | Ajo R Cacicedo L Navarro C | 2003 | Endocrinol2003,144,3: | 1 |
| 5 | Impact of weight loss in patients with head and neck carcinoma undergoing radiotherapy : is it an underestimated phenomenon&quest ; A radiation oncologist' s perspective显示文摘 | Cacicedo J Dal Pra A Alongi F | 2015 | European journal of clinical nutrition2015,,: | 1 |
| 6 | Acute exercise activates AMPK and eNOS in the mouse aorta显示文摘 | Cacicedo J M Gauthier M S Lebrasseur N K | 2011 | Am J Physiol Heart Circ Physiol2011,301,4: | 1 |
| 7 | Activation of AMP-activated protein kinase prevents lipotoxicity in retinal pericytes显示文摘 | CACICEDO JM BENJACHAREONWONG S Chou E | 2011 | Invest Ophthalmol Vis Sci2011,52,6: | 1 |
| 8 | Involvement of VIP on BDNF-induced somatostatin gene expression in cultured fetal rat cerebral cortical cells显示文摘 | Gemma Villuendas Franco Sánchez-Franco Nuria Palacios Miriam Fernández Lucinda Cacicedo | 2001 | Molecular Brain Research2001,,1: | 1 |
| 9 | Compara- tive analysis of thermoplastic masks versus vacuum cush- ions in stereotactic body radiotherapy 显示文摘 | Navarro-Martin A Cacicedo J Leaman O | 2015 | Radiat Oncol2015,10,: | 1 |
| 10 | AMPK inhibits fatty acid-induced increases in NF-KB transactivation in cultured hu- man umbilical vein endothelial ceils 显示文摘 | Cacicedo JM Yagihashi N Keaney JF Jr | 2004 | Biochem Biophys Res Commun2004,324,4: | 1 |
| 11 | Pal- mitate-induced apoptosis in cultured bovine retinal peri- cytes : roles of NAD(P) H oxidase, oxidant stress, and ceramide显示文摘 | Cacicedo JM Benjachareowong S Chou E | 2005 | Diabetes2005,54,6: | 1 |
| 12 | A novel inverse relationship between mefformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells显示文摘 | Nelson LE Valentine ILl Cacicedo JM | 2012 | Am J Physiol Cell Physiol2012,303,1: | 1 |
| 13 | AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells 显示文摘 | Cacicedo JM Yagihashi N Keaney J F Jr | 2004 | Biochem Biophys Res Commun2004,324,4: | 1 |
| 14 | Malonyl-CoA and AMP-activated protein kinase (AMPK) : possible links between insulin resistance in muscle and early endothelial cell damage in diabetes 显示文摘 | Ruderman N B Cacicedo J M hani S | 2003 | Biochem Soc Trans2003,31,1: | 1 |
| 15 | Acute exercise activates AMPK and eNOS in the mouse aorta显示文摘 | Cacicedo JM Gauthier MS Lebrasseur NK | 2011 | Am J Physiol Heart Circ Physiol2011,301,4: | 1 |
| 16 | Acute exercise activates AMPK and eNOS in the mouse aorta显示文摘 | Cacicedo JM Gauthier MS Lebrasseur NK | 2011 | Am J Physiol Heart Circ Physiol2011,301,4: | 1 |
| 17 | 'You Must Remember This': Trauma and memory in Catch- 22 and Slaughterhouse-Five 显示文摘 | Cacicedo Alberto | 2005 | Critique2005,46,4: | 1 |
| 18 | “ You must remember this” : Trauma andMemory in Catch - 22 and Slaughterhouse - Five显示文摘 | CACICEDO A | 2005 | Cri-tique2005,46,4: | 1 |
| 19 | Growth hormone gene expression and secretion in aging rats is age dependent and not age-associated weight increase related显示文摘 | Velasco B Cacicedo L Escalada J e t al | | 0,,03: | 1 |
| 20 | Acute exercise activates AMPK and eNOS in the mouse aorta显示文摘 | Cacicedo JM Gauthier MS Lebrasseur NK | | 0,,: | 1 |