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38篇 您的检索式:作者名="Caffrey T"
    题名 作者 年代 出处 被引量
1Relevance of MUC1 mucin variable number of tandem repeats polymorphism in H pylori adhesion to gastric epithelial cells显示文摘AIM:To evaluate the influence of MUC1 mucin variable number of tandem repeats (VNTR) variability on H pylori adhesion to gastric cells. METHODS: Enzyme linked immunosorbent assay (ELISA)-based adhesion assays were performed to measure the adhesion of different H pylori strains (HP26695 and HPTx30a) to gastric carcinoma cell lines (GP202 and MKN45) and GP202 clones expressing recombinant MUC1 with different VNTR lengths. RESULTS: Evaluation of adhesion results shows that H pylori pathogenic strain HP26695 has a significantly higher (P < 0.05) adhesion to all the cell lines and clones tested, when compared to the non-pathogenic strain HPTx30a. Bacteria showed a significantly higher (P < 0.05) adhesion to the GP202 cell line, when compared to the MKN45 cell line. Furthermore, both strains showed a significantly higher (P < 0.05) adhesion to GP202 clones with larger MUC1 VNTR domains. CONCLUSION: This work shows that MUC1 mucin variability conditions H pylori binding to gastric cells. The extent of bacterial adhesion depends on the size of theMUC1 VNTR domain. The adhesion is further dependent on bacterial pathogenicity and the gastric cell line. MUC1 mucin variability may contribute to determine H pylori colonization of the gastric mucosa.Natália R Costa Nuno Mendes Nuno T Marcos Celso A Reis Thomas Caffrey Michael A Hollingsworth Filipe Santos-Silva 2008World Journal of Gastroenterology2008,14,9:4
2The roles of Muscarinic re- ceptor subtypes in modulation of nasal ciliary action 显示文摘Yang B Mc Caffrey T V 1996Rhinology1996,34,3:1
3Thomsen- Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism 显示文摘Santos-Silva F Fonseca A Caffrey T 2005Glycobiology2005,5,5:1
4Duct epithelial cells cultured from human pancreas processed for transplantation retain differentiated ductal characteristics显示文摘 Caffrey T Hollingsworth M 1997Pancreas1997,15,3:1
5Novel splice variants of sFhl are upregulated in preeclampsia 显示文摘Heydarian M Mc Caffrey T Florea L 2009Placenta2009,30,3:1
6P-selectin expression in a metastatic pancreatic tumor cell line (SUIT-2)显示文摘Iwamura T Caffrey TC Kitamura N 1997Cancer Res1997,57,6:1
7P-selectin expression in a metastatic pancreatic tumor cell line (SUIT-2) 显示文摘Iwamura T Caffrey TC Kitamura N 1997Cancer Res1997,57,6:1
8Copper and lead con-centrations in salt marsh plants on the Suir Estuary,Ireland显示文摘Fitzgerald E J Caffrey J M Nasaratnam S T 2003Environ-mental Pollution2003,123,:1
9The structural and functional versatility of inositol phosphates显示文摘Caffrey J J Safrany S T Yang X N Yoshida M and Shears S B 0,,:1
10Development and implementation of a pediatric palliative care program显示文摘Pelant D Mc Caffrey T Beckel J 2010J Pediat Nurs2010,27,4:1
11Copper and lead concentrations in salt marsh plants on the Suir Estuary,Ireland显示文摘FITZGERALD E J CAFFREY J M NESARATNAM S T 2003Environmental Pollution2003,123,:1
12Development and implementatiou of a peditrie palliative care program 显示文摘Pelant D Mc Caffrey T Beckel J 2012Journarl of Pediatric Nars- ing2012,127,:1
13Development and Deployment of an Underway Radioactive Cesium Monitor off the Japanese Coast Near Fukushima Dai-ichi 显示文摘Caffrey J A Higley K A Farsoni A T 2012Journal of Enviromnental Radioactivity2012,111,:1
14Nitrogen cycling in sediments with estuarine populations of Potamogeton perfoliatus and Zoetera marina 显示文摘Caffrey T M Kemp W M 1999Mar Ecol Prog Ser1999,66,:1
15P - sehctin expression in a metastatic pancreatic tumor cell line (SUIT - 2) 显示文摘Iwamura T Caffrey TC Kitamura N 1997Cancer Research1997,57,6:1
16Copper and lead concentrations in salt marsh plants on the Suir Estuary,Ireland显示文摘Fitzgerald E J Caffrey J M Nesaratnam S T 2003Environmental Pollution2003,123,:1
17P-selectin expression in a mctastatic parcreativi tmor cell line(SUIT-Z) 显示文摘Iwamura T Caffrey TC Kitamura N 1997Cancer Res1997,57,6:1
18Thomsen-Friedenreich antigen expression in gastric carcinomas is associated with MUC1 mucin VNTR polymorphism显示文摘Samos-Silva F Fonseca A Caffrey T 2005Glycobiology2005,15,5:1
19Science basis for changing forest structure to modify wildfire behavior and sever-ity显示文摘GRAHAM R T MC CAFFREY S JAIN T B 2004Forest Service2004,4,:1
20P-selectin expression in a metastatic pancreatic tumor cell line (SUIT-2)显示文摘Iwamura T Caffrey TC Kitamura N 1997Cancer Res1997,57,6:1
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