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4篇 您的检索式:作者名="Can Gonen"
    题名 作者 年代 出处 被引量
1Cytomegalovirus colitis in a patient with Behcet’s disease receiving tumor necrosis factor alpha inhibitory treatment显示文摘Anti-tumor necrosis factor alpha (TNF-α) inhibitors are effective in the treatment of various inflammatory rheumatic conditions. Increased risks of serious infections are the major issues concerning the long-term safety of these agents. We present a case of a young male Behcet’s patient whose disease was complicated by cytomegalovirus (CMV) colitis. Colitis started 10 d after the third Infliximab dose and responded to the cessation of TNF blocking treatment and administration of ganciclovir. Tumor necrosis factor alpha and interferon gamma act at several levels in combating viral infections.CMV infections should be kept in mind and included in the differential diagnosis of severe gastrointestinal symptoms in patients receiving anti-TNF agents.Ismail Sari Merih Birlik Can Gonen Servet Akar Duygu Gurel Fatos Onen Nurullah Akkoc 2008World Journal of Gastroenterology2008,14,18:5
2Diagnostic yield of routine duodenal biopsies in iron deficiency anaemia: a study from Western Anatolia显示文摘Can Gonen Nusret Yilmaz Muhittin Yalcin Ilkay Simsek Omur Gonen 2007European Journal of Gastroenterology & Hepatology2007,,1:1
3Comparison of etomidate–remifentanil and propofol–remifentanil sedation in patients scheduled for colonoscopy显示文摘Salime Toklu Leyla Iyilikci Can Gonen Lugen Ciftci Ferim Gunenc Elvan Sahin Erol Gokel 2009European Journal of Anaesthesiology2009,,:1
4便携式肠道超声检查对克罗恩病治疗的影响显示文摘背景:肠道超声(IUS)是评估克罗恩病的一种有效的横断面影像技术。随着技术进步,便携式超声系统的应用越来越广泛,非影像专业的临床医生使用该设备有望大大提高患者的诊治效能。本研究旨在评估胃肠科医生使用便携式超声系统进行IUS检查,作为克罗恩病患者辅助影像学检查的诊断价值。方法:117例克罗恩病患者接受了IUS检查。记录检查前后的治疗决策。主要结局指标是评估IUS检查后治疗决策的改变。以基于患者所有相关资料评估后的多学科团队讨论所制定的治疗决策作为金标准,评估基于胃肠科医生进行IUS检查后所作出治疗决策的准确性。采用克罗恩病简单内镜评分(SES-CD)评估内镜下疾病活动度。结果:IUS检查后,47例(40.2%)患者最初的治疗决策发生了改变(P=0.001)。治疗决策的准确率由63.2%提高到90.6%(P<0.001)。IUS检查后,13例患者被评估为需要急诊外科/介入干预。肠镜(SES-CD≥3)与IUS异常发现用于治疗决策的准确率分别为94%和91%,灵敏度分别为95%和94%。结论:使用便携式超声系统进行IUS检查可显著提高临床决策的准确性。若获得进一步的数据支持,该检查模式可能会成为CD治疗决策的必需。Can Gonen Ali Surmelioglu Koray Kochan Serhat Ozer Ekrem Aslan Metin Tilki 2021Gastroenterology Report2021,9,5:0
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