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| 1 | Evaluation of anterior and posterior surfaces of the cornea using a dual Scheimpflug analyzer in keratoconus patients implanted with intrastromal corneal ring segments显示文摘AIM:To evaluate corneal parameters measured with a dual Scheimpflug analyzer in keratoconus patients implanted with intrastromal corneal ring segments(ICRS).METHODS:Fifty eyes of 40 keratoconus patients had Ferrara ICRS implantation from November 2010 to April2014.Uncorrected visual acuity(UCVA),best corrected visual acuity(BCVA),refraction,keratometry,asphericity,elevation,pachymetry,root mean square(RMS),spherical aberration and coma were studied.All patients were evaluated using a dual Scheimpflug system.RESULTS:The mean follow-up time after the procedure was 12.7mo.The mean UCVA improved from0.82 to 0.31(P<0.001);the mean BCVA improved from0.42 to 0.05(P<0.0001),the mean spherical refraction changed from-3.06 ±3.80 D to-0.80 ±2.5 D(P<0.0001)and the mean refraction astigmatism reduced from-4.51 ±2.08 D to-2.26±1.18 D(P<0.0001).The changes from preoperative to postoperative,in parameters of the anterior and posterior surface of the cornea,were statistically significant except the elevation posterior at the apex of the cornea and posterior asphericity.CONCLUSION:The implantation of Ferrara ICRS induces changes in both anterior and posterior surfaces of the cornea. | Leonardo Torquetti Carlos Arce Jesus Merayo-Lloves Guilherme Ferrara Paulo Ferrara Breenno Signorelli Armando Signorelli | 2016 | International Journal of Ophthalmology(English edition)2016，9，9： | 3 |
| 2 | Analyzing predictors of graft survival in patients undergoing liver transplantation with donors aged 70 years and over显示文摘AIM To increase the number of available grafts.METHODS This is a single-center comparative analysis performed between April 1986 and May 2016. Two hundred and twelve liver transplantation(LT) were performed with donors ≥ 70 years old(study group). Then, we selected the first cases that were performed with donors < 70 years old immediately after the ones that were performed with donors ≥ 70 years old(control group).RESULTS Graft and patient survivals were similar between both groups without increasing the risk of complications, especially primary non-function, vascular complications and biliary complications. We identified 5 risk factors as independent predictors of graft survival: recipient hepatitis C virus(HCV)-positivity [hazard ratio(HR) = 2.35; 95% confidence interval(CI): 1.55-3.56; P = 0.00]; recipient age(HR = 1.04; 95%CI: 1.02-1.06; P = 0.00); donor age X model for end-stage liver disease(D-MELD)(HR = 1.00; 95%CI: 1.00-1.00; P = 0.00); donor value of serum glutamic-pyruvic transaminase(HR = 1.00; 95%CI: 1.00-1.00; P = 0.00); and donor value of serum sodium(HR = 0.96; 95%CI: 0.94-0.99; P = 0.00). After combining D-MELD and recipient age we obtained a new scoring system that we called DR-MELD(donor age X recipient age X MELD). Graft survival significantly decreased in patients with a DR-MELD score ≥ 75000, especially in HCV patients(77% vs 63% at 5 years in HCV-negative patients, P = 0.00; and 61% vs 25% at 5 years in HCV-positive patients; P = 0.00). CONCLUSION A DR-MELD ≥ 75000 must be avoided in order to obtain the best results in LT with donors ≥ 70 years old. | Oscar Caso-Maestro Carlos Jiménez-Romero Iago Justo-Alonso Jorge Calvo-Pulido David Lora-Pablos Alberto Marcacuzco-Quinto Félix Cambra-Molero Alvaro García-Sesma Marina Pérez-Flecha Carlos Munoz- Arce Carmelo Loinaz-Segurola Alejandro Manrique-Municio | 2018 | World Journal of Gastroenterology2018，24，47： | 2 |
| 3 | Stress and exacerbation in ulcerative colitis: a prospective study of patients enrolled in remission显示文摘 | Susan Levenstein Cosimo Prantera Vilma Varvo Maria Lia Scribano Arnaldo Andreoli Carlo Luzi Massimo Arcà Eva Berto Giustina Milite Adriana Marcheggiano | 2000 | The American Journal of Gastroenterology2000，，： | 1 |
| 4 | A comparative assessment of empirical and lattice Boltzmann method-based drag models for simulation of gas-solid flow hydrodynamics in a bubbling fluidized bed显示文摘 | Carlos M. Romero Luna Luis R. Carrocci Gretta L.A.F. Arce Ivonete Avila | 2017 | Particuology2017，15，4： | 1 |
| 5 | Real-time implementation of a constrained MPC for efficient airflow control in a pem fuel cell 显示文摘 | Arce Alicia De1 Real Alejandro J Bordons Carlos | 2010 | IEEE Transaction on Industrial Electronics2010，57，6： | 1 |
| 6 | Temporal trends in areas at risk for concomitant tuberculosis in a hyperendemic municipality in the Amazon region of Brazil显示文摘Background Although preventable and curable,tuberculosis(TB)still occurs in poor or developing countries,mainly in metropolitan regions of larger cities.The disease is a serious public health problem,and is directly linked to social issues.We analyzed temporal trend variations in areas at risk for concomitant TB,and characterized the clinical and epidemiological profiles of cases in a hyperendemic municipality in the Amazon region of Brazil.Methods This ecological study was performed in the municipality of Manaus,in northern Brazil.The population comprised cases with concomitant pulmonary and extrapulmonary TB,registered on the Notifiable Diseases Information System(SINAN),between January 1,2009 and December 31,2018.For risk cluster detection,spatial and spatiotemporal scanning statistical techniques were used.The Spatial Variation in Temporal Trends(SVTT)approach was used to detect and infer clusters for significantly different time trends.Results Between 2009 and 2018,873 concomitant TB cases were registered in Manaus.By using purely spatial scanning statistics,we identified two risk clusters.The relative risk(RR)of the clusters was 2.21(95%confidence interval[CI]:1.57–2.88;P=0.0031)and 2.03(95%CI:1.58–2.58;P=0.0029).Using space-time scanning,we identified a risk cluster with an RR of 3.57(95%CI:2.84–4.41;P=0.014),between 2017 and 2018.For SVTT analyses,three clusters with spatial variations were detected in the significant temporal trends:SVTT 1(P=0.042),SVTT 2(P=0.046)and SVTT 3(P=0.036).Conclusions In Brazil,several TB-determining factors such as race/color,gender,low educational level and low income overlap in needy urban areas and communities,demonstrating that it is unlikely to reach the goals,agreed and launched with the END TB Strategy within the deadlines of international agreements,if there is no reduction in existing inequities determinants and risk of illness in the country. | Alexandre Tadashi Inomata Bruce Thais Zamboni Berra Felipe Lima dos Santos Yan Mathias Alves Ludmilla Leidianne Limirio Souza Antônio Carlos Vieira Ramos Luiz Henrique Arroyo Juliane de Almeida Crispim Ione Carvalho Pinto Pedro Fredemir Palha Aline Aparecida Monroe Mellina Yamamura Regina Célia Fiorati Ana Carolina Scarpel Moncaio Dulce Maria de Oliveira Gomes Ricardo Alexandre Arcêncio | 2020 | Infectious Diseases of Poverty2020，9，4： | 0 |
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