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您的检索式：作者名="Carolin Steffenhagen"
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| 1 | Enzymatic and non-enzymatic isolationsystems for adipose tissue-derived cells:current state of the art显示文摘In the past decade, adipose tissue became a highly interesting source of adult stem cells for plastic surgery andregenerative medicine. The isolated stromal vascular fraction (SVF) is a heterogeneous cell population including theadipose-derived stromal/stem cells (ASC), which showed regenerative potential in several clinical studies and trials.SVF should be provided in a safe and reproducible manner in accordance with current good manufacturing practices(cGMP). To ensure highest possible safety for patients, a precisely defined procedure with a high-quality control isrequired. Hence, an increasing number of adipose tissue-derived cell isolation systems have been developed.These systems aim for a closed, sterile, and safe isolation process limiting donor variations, risk for contaminations,and unpredictability of the cell material. To isolate SVF from adipose tissue, enzymes such as collagenase are used.Alternatively, in order to avoid enzymes, isolation systems using physical forces are available. Here, we provide anoverview of known existing enzymatic and non-enzymatic adipose tissue-derived cell isolation systems, which arepatented, published, or already on the market. | Eleni Oberbauer Carolin Steffenhagen Christoph Wurzer Christian Gabriel Heinz Redl Susanne Wolbank | 2015 | Cell Regeneration2015，4，1： | 1 |
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