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| 1 | Calcium-Dependent Protein Kinase CPK21 Functions in Abiotic Stress Response in Arabidopsis thaliana显示文摘钙依赖者蛋白质 kinases (CDPK ) 包括察觉到领域和 kinase 受动器领域的钙在一个分子以内在被联合的植物 serine/threonine 蛋白质 kinases 的一个家庭。到目前为止,在不能生活的应力发信号的生物功能仅仅为很少 CDPK isoforms 被报导了,而为这些 CDPK 的内在的生物化学的机制主要仍然是未知的。这里,我们证明从 Arabidopsis thaliana 的 CPK21 生物化学地响应 hyperosmotic 应力在 vivo 被激活。cpk21 的 Loss-of-function 幼苗对 hyperosmotic 应力更容忍,变异的植物关于标记基因表示和代谢物累积显示出增加的压力回答。在互补在 cpk21 异种背景衬里的转基因的 Arabidopsis,在哪个任何一个 CPK21 野类型,或带氨基酸的替换的全身的酶变体稳定地被表示,压力 responsitivity 被 CPK21 然而并非与 kinase 恢复不活跃的变体。生物化学的描述在 planta,综合并且净化的 CPK21 蛋白质表明在钙绑定领域以内,与 C 终端 EF3 主题和 EF4 主题相比的 N 终端 EF1 主题和 EF2 主题在他们对调整钙的 kinase 活动的贡献不同,为 N 终端 EF 手对建议一个关键角色。我们的数据为在不能生活的应力发信号作出贡献的 CPK21 提供证据并且建议 N 终端 EF 手对是控制 CPK21 的特性的一个察觉到钙的决定因素函数。 | Sandra Franz Britta Ehlert Anja Liese Joachim Kurth Anne-Claire Cazale Tina Romeis | 2011 | Molecular Plant2011，4，1： | 27 |
| 2 | <ce:link locator='fx1'/> <ce:link locator='fx2'/> Insulin Resistance in Chronic Hepatitis C: Association With Genotypes 1 and 4, Serum HCV RNA Level, and Liver Fibrosis显示文摘 | Rami Moucari Tarik Asselah Dominique Cazals–Hatem Hélène Voitot Nathalie Boyer Marie–Pierre Ripault Rodolphe Sobesky Michèle Martinot–Peignoux Sarah Maylin Marie–Hélène Nicolas–Chanoine Valérie Paradis Michel Vidaud Dominique Valla Pierre Bedossa Patrick | 2008 | Gastroenterology2008，，2： | 2 |
| 3 | Surgical strategieS,in patients with catarac- tand glaucoma显示文摘 | Verges C Cazal J Lavin C | 2005 | CurrOpin Ophthalmol2005，16，1： | 1 |
| 4 | Auditory sensori - neural alterations induced by salieylate显示文摘 | Cazals Y | 2000 | Prog Neurobiol2000，62，6： | 1 |
| 5 | Neurological damage in pelvic injuries; a continuous prospective series of 50 pelvic injuries treated with an iliosaeral lag screw显示文摘 | Tonetti J Cazal C Eid A | 2004 | Retour Au Numro2004，90，2： | 1 |
| 6 | Acoustic responses recorded from the saccule nundle on the eight nerve of the guinea pigs显示文摘 | Cicier A Cazals Y | | 0，，： | 1 |
| 7 | Changes in antioxidant activity during the ripening of jujube(Ziziphus mauritiana Lamk) 显示文摘 | Zozio S Servent A Cazal G | 2014 | Food Chemistry2014，150，： | 1 |
| 8 | Estimating differential quantities using polynomial fitting of osculating jets显示文摘 | Cazals F Pouget M | 2005 | Computer Aided Geo- metric Design2005，，22： | 1 |
| 9 | Neurological damage in pelvic injuries:a continuous prospective series of 50 pelvic injuries treated with an iliosacral lag screw显示文摘 | Tonetti J Cazal C Eid A | 2004 | Rev Chir Orthop Reparatrice Appar Mot2004，90，2： | 1 |
| 10 | Glucocorticoid- induced growth arrest of lung alveolar epithelial cells is associated with increased production of insulin-like growth factor binding protein-2 显示文摘 | Mouhieddine OB Cazals V Kuto E | 1996 | Endocrinology1996，137，1： | 1 |
| 11 | Clinical and molecular analysis of combined hepatocellular - cholangiocarcino- mas显示文摘 | Cazals - Harem D Rebouissou S Bioulac - Sage P | 2004 | J nepatol2004，41，2： | 1 |
| 12 | CDC25B phosphorylation by Aurora A occurs at the G2/M transition and is inhibited by DNA damage显示文摘 | Cazales M Schmitt E Montembault E | 2005 | Cell Cycle2005，4，9： | 1 |
| 13 | Surgical strategies in patients with cataract and glaucoma 显示文摘 | Verges C Cazal J Lavin C | 2005 | Curr Opin Ophthalmol2005，16，1： | 1 |
| 14 | Phosphorylation of CDC25B by Aurora A at the centrosome contributes to the G2-M transition显示文摘 | Dutertre S Cazales M Quaranta M | 2004 | Cell Sci2004，117，12： | 1 |
| 15 | ultiple biliary hamartomas: Magentic resonance features with histopathologie corrlation显示文摘 | Tohm-Noun C Cazals D Noun R | 2008 | European Radiology2008，18，3： | 1 |
| 16 | Oxidative burst and hypoosmotic stress in tobacco cell suspensions显示文摘 | Cazale A C RoueT-Mayer M A Barbier-Brygoo H | 1998 | Plant Physiology1998，116，2： | 1 |
| 17 | Effect of an hypoxia at 5% oxygen on global electrophysiological responses from normal and hydropic ears of awake guines pigs显示文摘 | Cazals Y Wu ZY Horner K | 1992 | Journal Dephysique IV(supplement)1992，2，： | 1 |
| 18 | Nuclear localization of CDC25B1 and serine 146 integrity are required for Induction of mitosis显示文摘 | Pelpel K Cazales M | 2002 | J Biological Chemistry2002，277，35： | 1 |
| 19 | Mteration in average spectrum of eochcleoneural activity by long-term Saheylate treatment in the guinea pig: a plausible index of tinnitus 显示文摘 | Cazal Y Homer K C Huang Z W | 1998 | J Neurophysiol1998，80，： | 1 |
| 20 | Smooth surface reconstruction via nat- ural neighbor interpolation of distance functions 显示文摘 | Boissonnat J D Cazals F | 2002 | Computer Geometry: Theory Applications2002，22，1： | 1 |
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