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| 1 | Quantitative and qualitative in vitro analysis of the stem cell potential of hematopoietic cells purified from murine skeletal muscle显示文摘鼠科的骨胳的肌肉包含造血的干细胞,而是这个潜力到目前为止没被学习份量上或品质上试管内。确定造血的干细胞潜力,我们在 long-termculture 开始使用了高度净化的 SP/CD45 (+) 房间房间(LTC-IC ) 试金。从鼠科的肌肉净化的 SP/CD45 (+) 房间人口被发现从肌肉与 1/640 .Single-cell-sorted SP/CD45 (+) 房间的 LTC-IC 频率举办重要干细胞活动在白天 16 点的展出柔韧的 proliferative 活动试管内(380 褶层扩大) ,特别在有 OP-9 层的文化以后,那也支持胚胎的干细胞。放大房间人口与 myeloid 的证据从单个房间 exhibitedmultilineage 区别能力发源,淋巴并且 NK 房间标记。因此,我们的结果证明能被 LTC-IC 试金确定的造血的干细胞第一次也在鼠科的骨胳的肌肉和表演存在,在单个房间的水平,这些房间展出多行的年龄区别能力和主要 proliferative 潜力。 | Celine Haond Frangoise Farace Martine Guillier Yann Lecluse Frederic Mazurier William Vainchenker Ali G Turhan | 2007 | Cell Research2007，17，9： | 4 |
| 2 | Autophagy is increased in cryptorchid testis resulting in abnormal spermatozoa显示文摘Autophagy is invoIved in spermatogenesis by regulating germ cell maturation.This catabolic process increases with hyperthermic conditions to prevent the accumulation of damaged organelles.Cryptorchidism is associated with impairment of germ cell maturation revealed by the presence of immature forms of sperm cells in ejaculates.The aim of the present study was to evaluate the status of autophagy in sperm cells from cryptorchid patients.Semen samples of cryptorchid patients and normozoospermic controls were analyzed by immuno cytochemistry and electron microscopy.Autophagy protei ns,autophagy-related protein 9(ATG9)and microtubule-associated protein,lA/lB-light chain 3(LC3)were localized by immunocytochemistry on the acrosome and on the equatorial segment of sperm cells.LC3 was also detected in the midpiece of cryptorchid sperm tail.Autophagy substrate p62 protein was present in the acrosome and in the postequatorial segment of sperm in control samples,but not in the cryptorchid ones.Transmission electron microscopy revealed double-membrane-limited autophagosomes in postequatorial part of spermatozoa head and midpiece in cryptorchid samples.Partly degraded mitochondria were frequently discerned in autophagic vacuoles.In conclusion,autophagy is increased in sperm cells from patients with cryptorchid history comparatively to control.Our work provides insights into the role of autophagy in the maturation and survival of human male gametes in pathological conditions.Thus,regulating autophagy could represent a potential way to improve sperm quality in cryptorchid men. | Marina G Yefimova Antoine Buschiazzo Agnes Burel Marie-Therese Lavault Celine Pimentel Guilhem Jouve Sylvie Jaillard Bernard Jegou Nicolas Bourmeyster Celia Ravel | 2019 | Asian Journal of Andrology2019，21，6： | 2 |
| 3 | Influence of humic substances on the toxic effects of cadmium and zinc to the green alga Pseudokirchneriella subcapitata 显示文摘 | Brahim K Celine G Michel P | 2003 | Chemoshere2003，53，8： | 1 |
| 4 | Identification of wax esters in latent print residues by GC-MS and their potential use as aging parameters显示文摘 | Agnes K Aline G Celine W | 2011 | J Forensic Ident2011，61，6： | 1 |
| 5 | Influence of colour type and previous cultivation on secondary metabolites in hypocotyls and leaves of maca (Lepidium meyenii Walpers) 显示文摘 | Celine C Diego A D G Bharathi A | 2010 | Journal of the Science of Food and Agriculture2010，90，5： | 1 |
| 6 | 查看详情显示文摘 | Aline R B Emilene M B Celine L Maria G R V Sergio L C F Bernhard W | | 0，，： | 1 |
| 7 | Cloned rabbits produced by nuclear transfer from adult somatic cells显示文摘 | Chesne Patrick Pierre G Adenot Celine Viglietta | 2002 | Nature Biotechnology2002，20，： | 1 |
| 8 | Aberrant rel/nfkb genes and activity in human cancer显示文摘 | Rayet B Gelinas C Celine G | 1999 | Oncogene1999，18，49： | 1 |
| 9 | Heat Shock Proteins 27 and 70 Anti-Apoptotic Proteins with Tumorigenic Properties 显示文摘 | Carmen G Mathilde B Celine D et a | 2006 | Cell Cycle2006，5，22： | 1 |
| 10 | 1-O-Alkylglyeerols Improve Boar Sperm Motility and Fertility 显示文摘 | Celine C Ve ronique G Aziz H | 2002 | Biology of Reproduction2002，66，2： | 1 |
| 11 | Comparison of the clinical history of symptomatic isolated muscular calf vein thrombosis显示文摘 | JEAN PG MARIE AS CELINE G | 2010 | J Vasc Surg2010，52，4： | 1 |
| 12 | Combined effects of docetaxel and angiostatin gene therapy in prostate tumor model显示文摘 | Ariane G Paule Opolon Celine B | 2003 | Mol Ther2003，7，6： | 1 |
| 13 | Factors related to persistent fatigue following completion of breast cancer treatment 显示文摘 | Celine G Lise F | 2004 | Oncol Nurs Forum2004，31，2： | 1 |
| 14 | Aberrant rel/nfκb genes and activity in human cancer显示文摘 | Beatrice R Celine G | 1999 | Oncogene1999，18，49： | 1 |
| 15 | A reversible polyelectrolyte involving aβ-cyclodextrin polymer and a cationic surfactant显示文摘 | Celine G Veronique W Catherine A | 2005 | Macromolecules2005，38，12： | 1 |
| 16 | Heat shock proteins 27 and 70 anti-apoptotic proteins with tumorigenic properties显示文摘 | Carmen G Mathilde B Celine D | | 0，，22： | 1 |
| 17 | Monitoring of Cryptosporidium and Giardia river contamination in Paris area 显示文摘 | Celine M Aurelien D Sylvie G | 2009 | Water Research2009，43，1： | 1 |
| 18 | Aberrant rel/nf-κb genes and activity inhuman cancer 显示文摘 | Beatrice R Celine G | 1999 | Oncogene1999，18，49： | 1 |
| 19 | Monitoring of Cryptosporidium and Giardia River Contamination in Paris Area显示文摘 | Celine M Aurelien D Sylvie G | 2009 | Water Research2009，43，1： | 1 |
| 20 | Solid-phase synthesis of isocoumarins: a traceless halocyelization approach显示文摘 | Marine P Vincent L Celine G | 2009 | J Org Chem2009，74，11： | 1 |
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