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| 1 | The 600-mm precipitation isoline distinguishes tree-ring-width responses to climate in China显示文摘The numerous temperature and precipitation reconstructions in China based on tree-ring-width data have played significant roles in furthering the understanding of past climate changes. However, the geographical variability in the responses of trees to climate variations in China remains largely undetermined. Here, we describe an important spatial boundary in the response of trees to climate variations, namely the 600-mm annual precipitation isoline. We found that, to the north of this line, tree-ring widths are usually positively correlated with precipitation and negatively correlated with growing-season temperature. To the south of this line, the tree-ring widths respond positively to temperature, and winter half-year temperatures are the main reconstructed parameters, especially on the third topographical step of China. We also found that precipitation reconstructions based on tree-ring data and the Palmer Drought Severity Index almost exclusively fall in the region of the 200- to 600-mm annual precipitation isolines, not other regions. Our findings indicate that, when using multiple tree-ring-width chronologies for large-scale past climate reconstructions, the climatic signal of each tree-ring-width series should be carefully considered. | Yu Liu Huiming Song Changfeng Sun Yi Song Qiufang Cai Ruoshi Liu Ying Lei Qiang Li | 2019 | National Science Review2019，6，2： | 8 |
| 2 | Competition between collective oblate rotation and non-collective prolate K isomerism in neutron-rich tungsten isotopes显示文摘Recent experiments open up the possibility to investigate oblate rotation-aligned states and prolate high-K isomers in neutron-rich tungsten isotopes.In the present work,we perform the projected-shell-model calculations for A ~ 190 tungsten nuclei.The 190 W results are compared with experimental data.The observed 8 + isomer is assigned as a two-quasiproton K π = 8 + configuration.Low-lying high-K four-quasiparticle states are predicted.Of particular interest is the prediction of the K π = 20 + state in 190,192 W,which may form a long-lived spin trap.In competition with the prolate high-K states,rotational alignment leads to near-yrast collective oblate rotation. | JIAO ChangFeng SHI Yue XU FuRong SUN Yang WALKER P M | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，9： | 5 |
| 3 | Indole-3-propionic Acid-aggravated CCl_(4)-induced Liver Fibrosis via the TGF-β1/Smads Signaling Pathway显示文摘Background and Aims:The pathogenesis of liver fibrosis involves liver damage,inflammation,oxidative stress,and intestinal dysfunction.Indole-3-propionic acid(IPA)has been demonstrated to have antioxidant,anti-inflammatory and anticancer activities,and a role in maintaining gut homeostasis.The current study aimed to investigate the role of IPA in carbon tetrachloride(CCl4)-induced liver fibrosis and explore the underlying mechanisms.Methods:The liver fibrosis model was established in male C57BL/6 mice by intraperitoneal injection of CCl4 twice weekly.IPA intervention was made orally(20 mg/kg daily).The degree of liver injury and fibrosis were assessed by serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),and histopathology.Enzyme-linked immunosorbent assay and quantitative real-time polymerase chain reaction(qPCR)were used to detect the inflammatory cytokines.The malondialdehyde(MDA),glutathione,glutathione peroxidase,superoxide dismutase,and catalase were determined via commercial kits.Hepatocyte apoptosis was detected by terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assay.The expression of mRNA and protein was assayed by qPCR,Western blotting,or immunohistochemical staining.Results:After IPA treatment,the ALT and AST,apoptotic cells,and pro-inflammatory factor levels were enhanced significantly.Moreover,IPA intervention up-regulated the expression of collagen I,α-smooth muscle actin,tissue inhibitor of matrix metalloproteinase-1,matrix metalloproteinase-2,transforming growth factor-β1(TGF-β1),Smad3,and phosphorylated-Smad2/3.Additionally,IPA intervention did not affect the MDA level.Attractively,the administration of IPA remodeled the gut flora structure.Conclusions:IPA aggravated CCl_(4)-induced liver damage and fibrosis by activating HSCs via the TGF-β1/Smads signaling pathway. | Fei Liu Changfeng Sun Yuanfang Chen Fei Du Yuxiang Yang Gang Wu | 2021 | Journal of Clinical and Translational Hepatology2021，9，6： | 5 |
| 4 | Source and composition of sedimentary organic matter in the head of Three Gorges Reservoir: a multiproxy approach using δ^(13)C,lignin phenols, and lipid biomarker analyses显示文摘A multiproxy approach including bulk organic carbon, δ^(13) C, lignin phenols, and lipid biomarker analyses were applied to characterize the source and composition of sedimentary organic matter in the head part of Three Gorges Reservoir. OM consisted of both natural(autochthonous and allochthonous) and anthropogenic inputs.The natural OM included input from vascular plants,especially non-woody angiosperms. The allochthonous input included plankton and microbial production, likely due to localized eutrophication. Anthropogenic inputs likely derived from petroleum input and/or urban activities.Other anthropogenic inputs were untreated sewage waste.These influences were concluded to be regionally specific point sources of pollution based on relative distributions and on the fact that molecular characteristics of sedimentary OM were not distributed smoothly along a gradient. | He Ding Changfeng Zhu Kai Zhang Shangbin Xiao Xingqian Cui Yongge Sun | 2017 | Acta Geochimica2017，36，3： | 4 |
| 5 | Stable Functionalization of Small Semiconducting Polymer Dots via Covalent Cross‐Linking and Their Application for Specific Cellular Imaging显示文摘 | Jiangbo Yu Changfeng Wu Xuanjun Zhang Fangmao Ye Maria Elena Gallina Yu Rong I‐Che Wu Wei Sun Yang‐Hsiang Chan Daniel T. Chiu | 2012 | Adv. Mater2012，，26： | 1 |
| 6 | Effects of Kallistatin on Oxidative Stress and Inflammation on Renal Ischemia-Reperfusion Injury in Mice显示文摘 | Shuqin Zhou Yingying Sun Yugang Zhuang Wei Zhao Yuanzhuo Chen Bojie Jiang Changfeng Guo Zhonglin Zhang Hu Peng Yanqing Chen | 2015 | Current Vascular Pharmacology2015，，2： | 1 |
| 7 | Experimental and simulation of single equilibrium stage separation of (methane + hydrogen) mixtures via forming hydrate显示文摘 | SUN Changyu MA Changfeng CHEN Guangjin | 2007 | Fluid Phase Equilibria2007，261，12： | 1 |
| 8 | The growth kinetics of hydrate film on the surface of gas bubble suspended in water or aqueous surfactant solution显示文摘 | SUN Changyu CHEN Guangjin MA Changfeng | 2007 | Journal of Crystal Growth2007，306，2： | 1 |
| 9 | The Effect of Cr on The Pitting Resistance of Oil Tube Steel in CO2 Corrosion System显示文摘 | Chen Changfeng Lu Minxu Sun Dongbai Zhang Zhonghua Chang Wei | 2005 | Corrosion2005，，6： | 1 |
| 10 | Identification and Expression Profile of a Neuropeptide LFRFamide-Like Gene During Different Stages of Gonadal Development in the Cephalopod Sepia pharaonis显示文摘Neuropeptides are widely distributed in vertebrates and invertebrates,regulating a variety of physiological activities in the organisms,such as metabolism,feeding and reproduction.In this study,to explore the function of neuropeptide LFRFamide in Sepia pharaonis,the full-length cDNA of LFRFamide-like gene(named SpLFRFL,MG869822.1)was identified with rapid amplification of cDNA ends(RACE)method.The sequence of SpLFRFL was 860 bp in length and encoded 188 amino acids containing 4 different mature peptides:1 copy of PHTPFRFamide,NSLFRFamide,TIFRFamide,and 3 copies of GNLFRFamide.Multiple alignment and phylogenetic analysis results showed that SpLFRFL shared high identity with LFRFamides of Sepia officinalis and Sepiella japonica and had the closest relationship with them.Through quantitative Real-time PCR(qRT-PCR),it was found that the SpLFRFL gene was highly expressed in the optic lobe and brain at three different stages during gonad development in both genders.Moreover,the four mature peptides at a concentration of 0.01μmol L^(−1) could inhibit the protein synthesis in the Chinese hamster ovary cell strain-K1(CHOK1)induced by SpGnRH.These data suggest that SpLFRFL might be involved in the development and reproduction of S.pharaonis.The results can contribute to future studies on neuropeptide evolution and function and benefit the cuttlefish farming. | QIU Jiayin SUN Lianlian LI Shuang ZHOU Xu CHI Changfeng ZHENG Libing | 2024 | Journal of Ocean University of China2024，23，2： | 0 |
| 11 | Physical mechanism of performance adjustment in selective buried oxide n-MOSFETs显示文摘Dear editor,FDSOI MOSFETs do not rely on channel doping to control short channel effects;they overcome the barriers of conventional bulk MOSFETs by means of scaling. Owing to the presence of the buried oxide insulator (BOX), FDSOI MOSFETs offer many additional benefits over bulk MOSFETs. | Qin HUANG Renhua LIU Yabin SUN Xiaojin LI Yanling SHI Changfeng WANG DuANDuan LIAO Ming TIAN | 2019 | Science China(Information Sciences)2019，62，6： | 0 |
| 12 | A highly conserved amino acid in high molecular weight glutenin subunit 1Dy12 contributes to gluten functionality and processing quality in wheat显示文摘Bread wheat(Triticum aestivum L.)is one of the most commonly consumed staples worldwide,with widespread uses in foods such as breads,noodles,cakes,and cookies(Veraverbeke and Delcour,2002).The specific cooking properties of wheat products are mainly conferred by the gluten proteins contained in wheat grains(Delcour et al.,2012).High molecular weight glutenin subunits(HMW-GSs)are important constituents of wheat gluten proteins,largely determining gluten elasticity and processing quality(Branlard and Dardevet,1985;Payne et al.,1988). | Changfeng Yang Qian Chen Mingming Xin Zhenqi Su Jinkun Du Weilong Guo Zhaorong Hu Jie Liu Huiru Peng Zhongfu Ni Qixin Sun Yingyin Yao | 2023 | Journal of Genetics and Genomics2023，50，11： | 0 |
| 13 | Climate-Vegetation Coverage Interactions in the Hengduan Mountains Area, Southeastern Tibetan Plateau, and Their Downstream Effects显示文摘Little is known about the mechanism of climate-vegetation coverage coupled changes in the Tibetan Plateau(TP)region,which is the most climatically sensitive and ecologically fragile region with the highest terrain in the world.This study,using multisource datasets(including satellite data and meteorological observations and reanalysis data)revealed the mutual feedback mechanisms between changes in climate(temperature and precipitation)and vegetation coverage in recent decades in the Hengduan Mountains Area(HMA)of the southeastern TP and their influences on climate in the downstream region,the Sichuan Basin(SCB).There is mutual facilitation between rising air temperature and increasing vegetation coverage in the HMA,which is most significant during winter,and then during spring,but insignificant during summer and autumn.Rising temperature significantly enhances local vegetation coverage,and vegetation greening in turn heats the atmosphere via enhancing net heat flux from the surface to the atmosphere.The atmospheric heating anomaly over the HMA thickens the atmospheric column and increases upper air pressure.The high pressure anomaly disperses downstream via the westerly flow,expands across the SCB,and eventually increases the SCB temperature.This effect lasts from winter to the following spring,which may cause the maximum increasing trend of the SCB temperature and vegetation coverage in spring.These results are helpful for estimating future trends in climate and eco-environmental variations in the HMA and SCB under warming scenarios,as well as seasonal forecasting based on the connection between the HMA eco-environment and SCB climate. | Congxi FANG Jinlei CHEN Chaojun OUYANG Lu WANG Changfeng SUN Quan ZHANG Jun WEN | 2024 | Advances in Atmospheric Sciences2024，41，4： | 0 |
| 14 | Photoblinkingpolymer dots shine in super-resolution fluorescence imaging显示文摘Subject Code:B03With the support by the National Natural Science Foundation of China,a collaborative study by the research groups led by Prof.Sun Yujie(孙育杰)from the State Key Laboratory of Membrane Biology,Biodynamic Optical Imaging Center(BIOPIC),School of Life Sciences,Peking University and Prof. | Sun Yujie (孙育杰) Wu Changfeng | 2017 | Science Foundation in China2017，25，3： | 0 |
| 15 | Imaging Fast Cellular Uptake of Polymer Dots via Receptor‑Mediated Endocytosis显示文摘During the past decade,semiconducting polymer dots(Pdots)have been prevailing in the family of fluorescent probes due to its high photon budget,excellent photo stability,and good biocompatibility.In this study,holo-Transferrin human(Tf)was utilized to covalently couple with Pdots for a highly efficient endocytosis process through transferrin receptors(TfRs)mediated internalization.As a result,the endocytosis efficiency of Tf-conjugated Pdots in HeLa cells dramatically increased as compared to that of unconjugated Pdots in the same condition.This acute increment demonstrates that holo-Transferrin molecules are of great capability for intracellular delivery of Pdots to TfRs overexpressed cells.The transportation route of Tf-conjugated Pdots is quite different from the uptake mechanism of unconjugated Pdots via nonspecific endocytic trafficking pathway.Considering the overexpression of TfRs in various cancer cells,Tf-conjugated Pdots hold potential to function as a nanocarrier for efficient drug delivery in cancer diagnostics and therapy. | Zezhou Sun Ye Yuan Qiong Li Zhihe Liu Changfeng Wu | 2018 | Journal of Analysis and Testing2018，2，1： | 0 |
| 16 | Structural homology of the strength for metallic glasses显示文摘The structure-property relationship,one of the central themes in materials science,is far from being well understood for metallic glasses(MGs)due to the great complexity of their amorphous structures.Based on the analysis of published experimental data for 165 MGs from more than 15 different alloy systems,the present study reveals a universal dependence of mechanical properties(Young’s moduli,shear moduli and yield strength)on simple structural parameters(the inter-atomic distance and/or valence electron density)originating from the interatomic potential and Fermi sphere-Brillouin zone interaction.This work establishes a structure-property relationship for metallic glasses and provides insights into the fundamentals of the mechanical properties of disordered systems. | Weiming Yang Xinfa Sun Haishun Liu Changfeng Yu Wenyu Li Akihisa Inoue DanielŞopud Jürgen Eckert Chunguang Tang | 2021 | Journal of Materials Science & Technology2021，，22： | 0 |
| 17 | Highly efficient and non-doped red conjugated polymer dot for photostable cell imaging显示文摘By introducing a naphthothiadiazole(NT)unit as the main building block,a non-doped and red emissive conjugated polymer poly(9,9-dihexylfluorene-alt-naphthothiadiazole)(PFNT)is readily obtained through a two-step synthesis.Since the NT unit has a large twist angle with its neighboring segment,the aggregation-induced quenching(AIQ)effect of PFNT can be effectively suppressed in the condensed state.As a result,the corresponding PFNT polymer dot(Pdot)exhibits a high fluorescence quantum yield of53.2%with peak emission at 616 nm,which is one of the most efficient red Pdots known.PFNT Pdot shows good biocompatibility and can be employed for living cell fluorescent imaging with high brightness.It also can be used for specific subcellular organelle imaging through immunofluorescence labeling.Furthermore,the PFNT Pdot demonstrates much better photostability for long-time cell fluorescence imaging than commercial red dyes.The high performances of PFNT Pdot make it a promising fluorescent probe for practical bioapplications. | Mengqi Wu Qidong Wei Caihong Xian Chunlei Dai Xuehan He Changfeng Wu Guoming Sun Lei Chen | 2023 | Chinese Chemical Letters2023，34，6： | 0 |
| 18 | Countermeasures of Financing Difficulties of Small and Micro Enterprises in China显示文摘 | SUN Changfeng | 2015 | International English Education Research2015，，12： | 0 |
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