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| 1 | Fast acceleration of “killer” electrons and energetic ions by interplanetary shock stimulated ULF waves in the inner magnetosphere显示文摘Energetic electrons and ions in the Van Allen radiation belt are the number one space weather threat. Understanding how these energetic particles are accelerated within the Van Allen radiation belt is one of the major challenges in space physics. This paper reviews the recent progress on the fast acceleration of 'killer' electrons and energetic ions by ultralow frequency (ULF) waves stimulated by the interplanetary shock in the inner magnetosphere. Very low frequency (VLF) wave-particle interaction is considered to be one of the primary electron acceleration mechanisms because electron cyclotron resonances can easily occur in the VLF frequency range. Recently, using four Cluster spacecraft observations, we have found that, after interplanetary shocks impact the Earth’s magnetosphere, energetic electrons in the radiation belt are accelerated almost immediately and continue to accelerate for a few hours. The time scale (a few days) for traditional acceleration mechanisms, based on VLF wave-particle interactions to accelerate electrons to relativistic energies, is too long to explain our observations. Furthermore, we have found that interplanetary shocks or solar wind pressure pulses, with even small dynamic pressure changes, can play a non-negligible role in radiation belt dynamics. Interplanetary shocks interaction with the Earth’s magnetosphere manifests many fundamental space physics phenomena including energetic particle acceleration. The mechanism of fast acceleration of energetic electrons in the radiation belt responding to interplanetary shock impacts consists of three contributing parts: (1) the initial adiabatic acceleration due to strong shock-related magnetic field compression; (2) followed by the drift-resonant acceleration with poloidal ULF waves excited at different L-shells; and (3) particle acceleration due to the quickly damping electric fields associated with ULF waves. Particles end up with a net acceleration because they gain more energy in the first half of this cycle than they lose in the second. The results reported in this paper cast a new light on understanding the acceleration of energetic particles in the Earth’s Van Allen radiation belt. The results of this study can likewise be applied to interplanetary shock interaction with other planets such as Mercury, Jupiter, Saturn, Uranus and Neptune, and other astrophysical objects with magnetic fields. | ZONG QiuGang WANG YongFu YUAN ChongJing YANG Biao WANG ChenRui ZHANG XiangYun | 2011 | Chinese Science Bulletin2011，56，12： | 11 |
| 2 | Recent Progress on Al_(2)O_(3)-C Refractories with Low/ultra-low Carbon Content:A Review显示文摘This work intends to provide a comprehensive review on the development of Al_(2)O_(3)-C refractories with low/ultra-low carbon content.It covers three parts:carbon materials,microstructure optimization of the refractory matrix by ceramic phases,and application of metal Al as raw material.Carbon black,expanded graphite,and ultrafine microcrystalline graphite,as price-competitive carbon materials,can be chosen to prepare the low-carbon Al_(2)O_(3)-C refractories after some special treatment.Ni/Co/Fe-catalyzed phenolic resin contributes to improving the properties of the low-carbon Al_(2)O_(3)-C refractories.The performance deterioration of the low-carbon Al_(2)O_(3)-C refractories can also be improved by in-situ formed or pre-synthesized ceramic phases.Metal Al,characterized by plasticity forming,acceleration of sintering,oxidation resistance,and high reactivity,can be used as raw materials to completely replace graphite,and the prepared resin bonded Al-Al_(2)O_(3)based refractories are one novel development direction of the ultra-low carbon Al_(2)O_(3)-C refractories. | ZHAO Chenrui YAN Mingwei LI Hongyu NIU Zhiwang LIANG Baoqing SHANG Junli | 2022 | China's Refractories2022，31，1： | 4 |
| 3 | Temperature effect on CRISPR-Cas9 mediated genome editing显示文摘Zinc-finger nuclease(ZFN), transcription activator-like effector nuclease(TALEN), and clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9(CRISPR-Cas9) are the most commonly used genome editing tools. Previous studies demonstrated that hypothermia treatment increased the mutation rates induced by ZFNs and TALENs in mammalian cells. Here, we characterize the effect of different culture temperatures on CRISPR-Cas9 mediated genome editing and find that the genome editing efficiency of CRISPR-Cas9 is significantly hampered by hypothermia treatment, unlike ZFN and TALEN. In addition, hyperthermia culture condition enhances genome editing by CRISPR-Cas9 in some cell lines, due to the higher enzyme activity and sg RNA expression level at higher temperature. Our study has implications on CRISPR-Cas9 applications in a broad spectrum of species, many of which do not live at 37 C. | Guanghai Xiang Xingying Zhang Chenrui An Chen Cheng Haoyi Wang | 2017 | Journal of Genetics and Genomics2017，44，4： | 2 |
| 4 | Placenta-derived IL-32β activates neutrophils to promote preeclampsia development显示文摘Immune activation at the maternal-fetal interface is a main pathogenic factor of preeclampsia(PE).Neutrophils(PMNs)are activated in PE patients,but the mechanism and consequences of PMN activation need to be further explored.Here,we demonstrated that interleukin-32(IL-32)expression was significantly upregulated in syncytiotrophoblasts(STBs)and that IL-32β was the major isoform with increased expression in the placenta of severe PE(sPE)patients.Furthermore,the level of IL-32 expression in the placenta was correlated with its level in the serum of sPE patients,indicating that IL-32 in the serum is derived mainly from the placenta.Then,in vitro experiments showed that IL-32β could highly activate PMNs and that these IL-32β-activated PMNs were better able to adhere to endothelial cells(HUVECs)and enhance the expression of vascular cell adhesion molecule-1(VCAM-1)and intercellular cell adhesion molecule-1(ICAM-1)in HUVECs,which could be reversed by preincubation with the NADPH oxidase inhibitor VAS 2870.In addition,we showed that IL-32β mainly activated PMNs by binding to proteinase 3.Finally,IL-32β administration induced a PE-like phenotype in a pregnant mouse model.This study provides evidence of the involvement of IL-32β in the pathogenesis of PE. | Dan Liu Qiang Li Hailin Ding Guangfeng Zhao Zhiyin Wang Chenrui Cao Yimin Dai Mingming Zheng Xiangyu Zhu Qianwen Wu Ya Wang Honglei Duan Huirong Tang Xianyan Lu Yayi Hou Yali Hu | 2021 | Cellular & Molecular Immunology2021，18，4： | 2 |
| 5 | SAW-RFID en-abled temperature sensor显示文摘 | Kang Along Zhang Chenrui Ji Xiaojun | 2013 | Sensors and Actuators A : Physical2013，201，： | 1 |
| 6 | Generation of a Golden Leaf Triploid Poplar by Repressing the Expression of GLK Genes显示文摘Poplar trees are excellent varieties widely used for gardening and greening.However,their single color and floating fluffy seeds are major disadvantages.Plant species or varieties with variegated leaves are desperately needed to meet various demands for gardens,urban greening and landscape decoration,as they produce rich foliage colors that are aesthetically pleasing and functional.In this study,we generated a golden leaf triploid poplar(P.alba×P.berlinensis)by repressing the expression of GLK(Golden2-like)genes in leaves.The triploid golden leaf poplar had reduced chlorophyll content but almost no change in the growth rate.It has great potential in landscaping once it passes safety assessments. | Yidi Li Chenrui Gu Huixin Gang Yu Zheng Guifeng Liu Jing Jiang | 2021 | Forestry Research2021，1，1： | 1 |
| 7 | 显示文摘 | CHENRui(陈蕊) ZHANGJun(张骏) LIXiao-long(李晓龙) | 2012 | 光谱学与光谱分析2012，32，5： | 1 |
| 8 | SAW-RFID En- abled Temperature Sensor显示文摘 | Along Kang Chenrui Zhang Xiaojun Ji | 2013 | Sensors and Actuators A Physical2013，201，： | 1 |
| 9 | Investigation on the Absorption Kinetics of Chlorogenic Acid in Rats by HPLC显示文摘 | Ren Jing Jiang Xuehua Li Chenrui | 2007 | Archives of Pharmacal Research2007，30，7： | 1 |
| 10 | Molecular Imaging in Tracking Tumor Stem-Like Cells显示文摘 | Tian Xia Han Jiang Chenrui Li Mei Tian Hong Zhang Enzhong Li | 2012 | Journal of Biomedicine and Biotechnology2012，，： | 1 |
| 11 | Contents of major bioactive flavones in proprietary traditional Chinese medicine products and reference herb of radix scutellariae 显示文摘 | Chenrui Li Limin Zhou Ge Lin | 2009 | Journal of Pharmaceutical and Biomedical Analysis2009，，3： | 1 |
| 12 | Sensitive label-free electrochemical immunoassay by electroeatalytie amplification 显示文摘 | Chen Chenrui Liu Dengyou Wu Zaisheng | 2009 | Electrochemistry Communications2009，11，： | 1 |
| 13 | Safety evalution of chemical pesticides to environment — W Toxicity evaluation of chemical pesticides to bee [J]显示文摘 | CHENRui(陈锐) ZHANGAiyun(张爱云) GONGRuizhong(袭瑞忠) etal | 1987 | 农 村生态环境1987，，1： | 1 |
| 14 | TheErrorofOpticalTrueTimeDelayNetworkCausedbyOpticalSwitches显示文摘 | Chenrui Zhengxiaoping Zhanghanyi | 2005 | ProceedingsofSPIE2005，2625，： | 1 |
| 15 | Toxicity test methods of pesticide to silkworm [J]显示文摘 | CHENRui(陈锐) ZHANGAiyim(张爱云) CA1Daoji(蔡道基) | 1986 | 农村生态环境1986，10，4： | 1 |
| 16 | 显示文摘 | Tseng Fengpo Tseng Chenrui Chang Fengchih | 2005 | Jour nal of Polymer Research2005，12，6： | 1 |
| 17 | Optimizing electric vehicle charging with energy storage in the electricity market显示文摘 | Jin Chenrui Tang Jian Ghosh P | 2013 | IEEE Transactions on Smart Grid2013，4，1： | 1 |
| 18 | Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones 显示文摘 | LI Chenrui LIN Ge ZUO Zhong | 2011 | Biopharm Drug Dispos2011，32，8： | 1 |
| 19 | Experi-mental and Numerical Study of Convection Heat Transferof CO2 at Supercritical Pressures During Cooling in SmallVertical Tube 显示文摘 | JIANG Peixue ZhAO Chenrui SHI Runfu | 2009 | International Journal of Heat and MassTransfer2009，52，21： | 1 |
| 20 | Preparation and characterization of polystyrene-clay nanocomposites by free-radical polymerization显示文摘 | Tseng Chenrui Wu Jengyue | 2002 | J Appl Polym Sci2002，85，7： | 1 |
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