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8篇 您的检索式:作者名="Chitneni"
    题名 作者 年代 出处 被引量
1Identification of impurities in erythromycin by liquid chromatography-mass spectrometric detection显示文摘Kumar Chitneni S Govaerts C Adams E 2004J Chromatogr A2004,1056,1:1
2Identification of impurities in erythromycin by liquid chromatography-mass spectrometric detection显示文摘Chitneni S K Govaerts C Adams E 2004J Chromatogr A2004,1056,:1
3Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for Determination of Artemisinin in Rat Plasma显示文摘Elhassan Gamal Yuen Kah Wong Jiawoei Chitneni Mallikarjun Al-Dahli Samer Khan Jiyauddin Javed Qureshi 2011Journal of Chemistry and Chemical Engineering2011,5,1:1
4Copper signaling ax- is as a target for prostate cancer therapeutics 显示文摘Sail R Nelson ER Chitneni SK 2014Cancer Res2014,74,20:1
5Preparation and in vitro evaluation of mebeverine HCl colon-targeted drug delivery system显示文摘Abdullah GZ Abdulkarim MF Chitneni M 0,,04:1
6Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET 显示文摘Deroose CM Chitneni SK Gijsbers R 2012Nucl Med Biol2012,39,8:1
7Improved synthesis and metabolic stability analysis of the dopamine transporter ligand FECT 显示文摘Chitneni SK Garreau L Cleynhens B 2008Nucl ned Biol2008,35,1:1
8Enhancement of solubility and therapeutic potential of poorly soluble lovastatin by SMEDDS formulation adsorbed on directly compressed spray dried magnesium aluminometasilicate liquid loadable tablets: A study in diet induced hyperlipidemic rabbits显示文摘The aim of present study was to formulate and evaluate a self-microemulsifying drug delivery systems(SMEDDS)containing lovastatin and to further explore the ability of porous Neusilin■ US2 tablet as a solid carrier for SMEDDS.SMEDDS formulations of varying proportions of peceol,cremophor RH 40 and transcutol-P were selected and subjected to invitro evaluation,including dispersibility studies,droplet size,zeta potential measurement and release studies.The results indicated that the drug release profile of lovastatin from SMEDDS formulations was statistically significantly higher(p-value<0.05)than the plain lovastatin powder.Thermodynamic stability studies also confirmed the stability of the prepared SMEDDS formulations.The optimized formulation,which consists of 12% of peceol,44% of cremophor RH 40,and 44% of transcutol-P was loaded into directly compressed liquid loadable tablet of Neusilin■ US2 by simple adsorption method.In order to determine the ability of Neusilin®US2 as a suitable carrier pharmacodynamics study were also carried out in healthy diet induced hyperlipidemic rabbits.Animals were administered with both liquid SMEDDS and solid SMEDDS as well.From the results obtained,Neusilin■ was found to be a suitable carrier for SMEDDS and was equally effective in reducing the elevated lipid profile.In conclusion,liquid loadable tablet(LLT)is predicted to be a promising technique to deliver a liquid formulation in solid state.Mohd Javed Qureshi Chitneni Mallikarjun Wong Gan Kian 2015Asian Journal of Pharmaceutical Sciences2015,10,1:0
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