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| 1 | Increased susceptibility for intrahepatic cholestasis of pregnancy and contraceptive-induced cholestasis in carriers of the 1331T>C polymorphism in the bile salt export pump显示文摘AIM: To study the association of three common ABCB11 and ABCC2 polymorphisms (ABCB11: 1331T>C V444A; ABCC2: 3563T>A V1188E and 4544G>A C1515Y) with intrahepatic cholestasis of pregnancy (ICP) and contraceptive-induced cholestasis (CIC). METHODS: ABCB11 and ABCC2 genotyping data were available from four CIC patients and from 42 and 33 ICP patients, respectively. Allele-frequencies of the studied polymorphisms were compared with those in healthy pregnant controls and Caucasian individuals. Furthermore, serum bile acid levels were correlated with the presence or absence of the 1331 C allele.RESULTS: The ABCB11 1331T>C polymorphism was significantly more frequent in cholestatic patients than in pregnant controls: C allele 76.2% (CI, 58.0-94.4) vs 51.3% (CI 35.8-66.7), respectively (P = 0.0007); and CC allele 57.1% (CI 36.0-78.3) vs 20% (CI 7.6-32.4), respectively (P = 0.0065). All four CIC patients were homozygous carriers of the C allele. In contrast, none of the studied ABCC2 polymorphism was overrepresented in ICP or CIC patients. Higher serum bile acid levels were found in carriers of the 1331CC genotype compared to carriers of the TT genotype.CONCLUSION: Our data support a role for the ABCB11 1331T>C polymorphism as a susceptibility factor for the ←←← development of estrogen-induced cholestasis, whereas no such association was found for ABCC2. Serum bile acid and γ-glutamyl transferase levels might help to distinguish ABCB4- and ABCB11-related forms of ICP and CIC. | Yvonne Meier Tina Zodan Carmen Lang Roland Zimmermann Gerd A Kullak-Ublick Peter J Meier Bruno Stieger Christiane Pauli-Magnus | 2008 | World Journal of Gastroenterology2008，14，1： | 20 |
| 2 | Perfusing the Cold Brain: Optimal Neuroprotection for Aortic Surgery显示文摘 | James C. Halstead Christian Etz D. Matthias Meier Ning Zhang David Spielvogel Donald Weisz Carol Bodian Randall B. Griepp | 2007 | The Annals of Thoracic Surgery2007，，3： | 1 |
| 3 | Real-time optoacoustic tomography of indocyanine green perfusion and oxygen- ation parameters in human finger vasculature显示文摘 | CHRISTIAN LUTZWEILER REINHARD MEIER ERNST RUMMENY | 2014 | Op- tics Letters2014，39，14： | 1 |
| 4 | Incidence of drug-induced liver injury in medical inpatients显示文摘 | Yvonne Meier Marzia Cavallaro Malgorzata Roos Christiane Pauli-Magnus Gerd Folkers Peter J. Meier Karin Fattinger | 2005 | European Journal of Clinical Pharmacology2005，，2： | 1 |
| 5 | Glycoprotein-associated amino acid exchangers: broadening the range of transport specificity显示文摘 | Fran?ois Verrey Christian Meier Grégoire Rossier Lukas C. Kühn | 2000 | Pflügers Archiv - European Journal of Physiology2000，，4： | 1 |
| 6 | Influence of Donor Age on Islet Isolation and Transplantation Outcome显示文摘 | Nadja Niclauss Domenico Bosco Philippe Morel Sandrine Demuylder-Mischler Coralie Brault Laure Milliat-Guittard Cyrille Colin Geraldine Parnaud Yannick D. Muller Laurianne Giovannoni Raphael Meier Christian Toso Lionel Badet Pierre-Yves Benhamou Thierry Be | 2011 | Transplantation2011，，3： | 1 |
| 7 | Assessment of right ventricular systolic function: Comparison between cardiac magnetic resonance derived ejection fraction and pulsed-wave tissue Doppler imaging of the tricuspid annulus显示文摘 | Andreas Wahl Fabien Praz Markus Schwerzmann Harald Bonel Simon C. Koestner Roger Hullin Jean-Paul Schmid Thomas Stuber Etienne Delacrétaz Otto M. Hess Bernhard Meier Christian Seiler | 2010 | International Journal of Cardiology2010，，1： | 1 |
| 8 | A multi-mode super-fano mechanism for enhanced third harmonic generation in silicon metasurfaces显示文摘We present strong enhancement of third harmonic generation in an amorphous silicon metasurface consisting of elliptical nano resonators.We show that this enhancement originates from a new type of multi-mode Fano mechanism.These‘Super-Fano’resonances are investigated numerically in great detail using full-wave simulations.The theoretically predicted behavior of the metasurface is experimentally verified by linear and nonlinear transmission spectroscopy.Moreover,quantitative nonlinear measurements are performed,in which an absolute conversion efficiency as high as η_(max)≈2.8×10^(-7) a peak power intensity of 1.2 GW cm^(-2) is found.Compared to an unpatterned silicon film of the same thickness amplification factors of up to ~900 are demonstrated.Our results pave the way to exploiting a strong Fano-type multi-mode coupling in metasurfaces for high THG in potential applications. | David Hahnel Christian Golla Maximilian Albert Thomas Zentgraf Viktor Myroshnychenko Jens Forstner Cedrik Meier | 2023 | Light(Science & Applications)2023，12，5： | 1 |
| 9 | Ultrafiltration with pre-coagulation in drinking water production-Literature review显示文摘 | Philipp Meier Farhad Salehi Christian Kazner | 2006 | TECHNEAU2006，06，： | 1 |
| 10 | Historical aspects and rele- vance of the human coronary collateral circulation 显示文摘 | Christian Seller Pascal Meier | 2013 | Curt Cardiol Rev2013，10，1： | 1 |
| 11 | Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury显示文摘 | Carmen Lang Yvonne Meier Bruno Stieger Ulrich Beuers Thomas Lang Reinhold Kerb Gerd A. Kullak-Ublick Peter J. Meier Christiane Pauli-Magnus | 2007 | Pharmacogenetics and Genomics2007，，1： | 1 |
| 12 | Iota-Carrageenan is a potent inhibitor of rhinovirus infection显示文摘 | Andreas Grassauer Regina Weinmuellner Christiane Meier | 2008 | Virology Journal2008，5，： | 1 |
| 13 | Correlation of Intravascular Ultrasound Findings With Histopathological Analysis of Thrombus Aspirates in Patients With Very Late Drug-Eluting Stent Thrombosis显示文摘 | Stéphane Cook Elena Ladich Gaku Nakazawa Parham Eshtehardi Michel Neidhart Rolf Vogel Mario Togni Peter Wenaweser Michael Billinger Christian Seiler Steffen Gay Bernhard Meier Werner J. Pichler Peter Jüni Renu Virmani Stephan Windecker | 2009 | Circulation2009，，： | 1 |
| 14 | Percutaneous Closure of Patent Foramen Ovale in Patients With Paradoxical Embolism: Long-Term Risk of Recurrent Thromboembolic Events显示文摘 | Stephan Windecker Andreas Wahl Tushar Chatterjee Ali Garachemani NA R. Eberli Christian Seiler Bernhard Meier | 2000 | Circulation: Journal of the American Heart Association2000，，8： | 1 |
| 15 | Elevated C-reactive protein and homocysteine values: cardiovascular risk factors in hypothyroidism? A cross-sectional and a double-blind, placebo-controlled trial显示文摘 | Mirjam Christ-Crain Christian Meier Merih Guglielmetti Peter R. Huber Walter Riesen Jean-Jacques Staub Beat Müller | 2002 | Atherosclerosis2002，，2： | 1 |
| 16 | Late Results After Percutaneous Closure of Patent Foramen Ovale for Secondary Prevention of Paradoxical Embolism Using the Amplatzer PFO Occluder Without Intraprocedural Echocardiography显示文摘 | Andreas Wahl Tony Tai Fabien Praz Markus Schwerzmann Christian Seiler Krassen Nedeltchev Stephan Windecker Heinrich P. Mattle Bernhard Meier | 2009 | JACC: Cardiovascular Interventions2009，，2： | 1 |
| 17 | Hepatocyte Transplantation in an Acute Liver Failure Due to Mushroom Poisoning显示文摘 | Andrea Schneider Masoumeh Attaran Peter N. Meier Christian Strassburg Michael P. Manns Michael Ott Marc Barthold Lubomir Arseniev Thomas Becker Bernd Panning | 2006 | Transplantation2006，，8： | 1 |
| 18 | Patent Foramen Ovale Screening by Ear Oximetry in Divers显示文摘 | Michael Billinger Markus Schwerzmann Wilhelm Rutishauser Andreas Wahl Stephan Windecker Bernhard Meier Christian Seiler | 2013 | The American Journal of Cardiology2013，，2： | 1 |
| 19 | The Adjustable proGAV Shunt: A Prospective Safety and Reliability Multicenter Study显示文摘 | Christian Sprung Hans-Georg Schlosser Johannes Lemcke Ullrich Meier Martina Messing-Jünger Hans Axel Trost Friedrich Weber Christoph Schul Veit Rohde Hans-Christian Ludwig Jürgen H?pfner Abolghassem Sepehrnia M. Javad Mirzayan Joachim K. Krauss | 2010 | Neurosurgery2010，，3： | 1 |
| 20 | Biomimetic membranes designed from amphiphilic block copolymers显示文摘 | Mecke Almut Dittrich Christian Meier W | 2006 | Soft Matter2006，，2： | 1 |
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