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| 1 | Gastric intestinal metaplasia is associated with gastric dysplasia but is inversely correlated with esophageal dysplasia显示文摘AIM To determine which clinical factors might be associated with gastric intestinal metaplasia(IM) in a North American population.METHODS Pathology and endoscopy databases at an academicmedical center were reviewed to identify patients with and without gastric IM on biopsies for a retrospective cohort study. Patient demographics, insurance status, and other clinical factors were reviewed.RESULTS Four hundred and sixty-eight patients with gastric IM(mean age: 61.0 years ± 14.4 years, 55.5% female) and 171 without gastric IM(mean age: 48.8 years ± 20.8 years, 55.0% female) were compared. The endoscopic appearance of atrophic gastritis correlated with finding gastric IM on histopathology(OR = 2.05, P = 0.051). Gastric IM was associated with histologic findings of chronic gastritis(OR = 2.56, P < 0.001), gastric ulcer(OR = 6.97, P = 0.015), gastric dysplasia(OR = 6.11, P = 0.038), and gastric cancer(OR = 6.53, P = 0.027). Histologic findings of Barrett's esophagus(OR = 0.28, P = 0.003) and esophageal dysplasia(OR = 0.11, P = 0.014) were inversely associated with gastric IM. Tobacco use(OR = 1.73, P = 0.005) was associated with gastric IM.CONCLUSION Patients who smoke or have the endoscopic finding of atrophic gastritis are more likely to have gastric IM and should have screening gastric biopsies during esophagogastroduodenoscopy(EGD). Patients with gastric IM are at increased risk for having gastric dysplasia and cancer, and surveillance EGD with gastric biopsies in these patients might be reasonable. | Justin M Gomez James T Patrie Wissam Bleibel Jeanetta W Frye Bryan G Sauer Vanessa M Shami Edward B Stelow Christopher A Moskaluk Andrew Y Wang | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，2： | 3 |
| 2 | Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus 显示文摘 | CHRISTOPHER G B SARAH F CECILIA M L | 2010 | PLoS One2010，5，14： | 1 |
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| 4 | Transgenic pigs as bioreactors: a comparison ofgamma-carboxylation of glutamic acid in recombinant humanprotein C and factor Ⅸ by the mammary gland显示文摘 | KEVIN E V C STEPHEN P B CHRISTOPHER G R | 1999 | Genetic Analysis: Biomolecular Engineering1999，15，： | 1 |
| 5 | Development of chromium nltride coatings substituting titanium nltrlde 显示文摘 | Günter B Christoph F Erhard B | 1996 | Surface and Coatings Technology1996，8687，1： | 1 |
| 6 | Synthetic approaches to an iso- structural Series of redox-active, metal tris(bipyridine)core dendrimers显示文摘 | Hong Y R Christopher B G | 2003 | J OrgChem2003，68，： | 1 |
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| 14 | Impact of conization type on the resected cone volume : results of a retrospective multi-center study显示文摘 | Christoph G Lindsay B Gerhard S | 2013 | Arch Gynecol Obstet2013，288，5： | 1 |
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| 16 | Real-time single - molecule imaging of the infection pathway of an adeno - associated virus 显示文摘 | Seisenberger G Martin U R Christoph B | 2001 | Science2001，294，： | 1 |
| 17 | Evidence of the effects of water quality on residential land prices 显示文摘 | Christopher G L Nancy E B | 2000 | Journal of Environmental Economies and Manage- ment2000，39，2： | 1 |
| 18 | Tacrolimus for the treatment of fistulas in patients with crohn’s disease: a randomized, placebo-controlled trial显示文摘 | William J Sandborn Daniel H Present Kim L Isaacs Douglas C Wolf Eugene Greenberg Stephen B Hanauer Brian G Feagan Lloyd Mayer Therese Johnson Joseph Galanko Christopher Martin Robert S Sandler | 2003 | Gastroenterology2003，，2： | 1 |
| 19 | Virulence-as- sociated gene profiling of Streptococcus suis isolates by PCR 显示文摘 | Luciana M G S Christoph G B Thomas R | 2006 | Vet Microbiol2006，115，： | 1 |
| 20 | Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans显示文摘 | Rhee Eugene P Cheng Susan Larson Martin G Walford Geoffrey A Lewis Gregory D McCabe Elizabeth Yang Elaine Farrell Laurie Fox Caroline S O’Donnell Christopher J Carr Steven A Vasan Ramachandran S Florez Jose C Clish Clary B Wang Thomas J Ger | 2011 | Journal of Clinical Investigation2011，，4： | 1 |
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