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| 1 | Antidiabetic principles of Loranthus micranthus Linn.parasitic on Persea americana显示文摘Objective:To explore antidiabetic principles of the Eastern Nigeria mistletoe,Loranlhus micranthus Linn,parasitic on Persea Americana.Methods:The weakly acidic fraction of the aqueous methanol extract of the leaves of Loranlhus micranthus(Linn.) was isolated and tested for its antidiabetic activities.The isolation of the weakly acidic fraction was carried out following established physico-chemical based procedures.Furthermore,alloxan-induced diabetic rats were treated intraperitoneally(ip) with 250 mg/kg and 400 mg/kg of the weakly acidic fraction, glibenclamide 10 mg/kg(positive control) and 2 mg/kg of 3%v/v tween 20(negative control).The sugar levels of the treated and untreated animals were determined by withdrawing the blood at regular intervals and testing them with an automated glucometer.The phytochemical analysis of the acidic fraction was carried out using standard procedures.Chromatographic techniques were employed in the subsequent isolation and purification of the constituents of the weakly acidic fraction.Results:It was shown that the maximum effect of the weakly acidic fraction was obtained at 24 hours after administration and was found to be statistically comparable with that of the positive control.The phytochemical analysis revealed the presence of steroids,terpenoids, alkaloids,flavonoids,glycosides,carbohydrates,saponins,and acidic compounds in the crude extract and carbohydrates,flavonoids.terpenoids and oil in the weakly acidic fraction.Further purification of the weakly acidic fraction of the methanol extract using thin layer chromatography shows that toluene:methanol:diethyl amine(3:1:1) and chloroform:methanol:diethyl amine (9:1:1) are the best solvent system for the isolation of the various components of the weakly acidic fraction of the crude methanol extract of Loranlhus micranthus.Conclusions:The present study has led to the conclusion that the weakly acidic fraction of the plant under study has the potent antidiabetic activity and that the various components can be isolated using basic chromatographic techniques. | Patience Ogoamaka Osadebe Edwin Ogechukwu Omeje Sylvester Chukwuemeka Nworu Charles Okechukwu Esimone Philip Felix Uzor Ernest kenechukwu David John Uchechukwu Uzoma | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，8： | 4 |
| 2 | Quality assurance in blood culture: A retrospective study of blood culture contamination rate in a ter- tiary hospital in Nigeria显示文摘 | Chukwuemeka IK Samuel Y | 2014 | Niger Med J2014，55，3： | 1 |
| 3 | Hypoglycemic activity of leaves of Acanthus montanus T Anderson (Acanthaceae) in rats显示文摘 | CHINWE VICTORIA UKWE CHUKWUEMEKA MICHAEL UBAKA | 2011 | International Journal of Diabetes in Developing Countries2011，31，1： | 1 |
| 4 | Role of integrative pharmacoki- netics and pharmacodynamic optimization strategy in the man- agement of Parkinson' s disease patients experiencing motor fluctuations with levodopa显示文摘 | Chukwuemeka S Okereke | 2002 | J Pharm Pharmaceut Sci2002，5，： | 1 |
| 5 | How to Manage the Left Subclavian Artery During Endovascular Stenting for Thoracic Aortic Dissection? An Assessment of the Evidence显示文摘 | Syed M. Rehman Joshua A. Vecht Ryan Perera Rozh Jalil Srdjan Saso Emaddin Kidher Andrew Chukwuemeka Nicholas J. Cheshire Mohamad S. Hamady Ara Darzi Richard G. Gibbs Jon R. Anderson Thanos Athanasiou | 2010 | Annals of Vascular Surgery2010，，7： | 1 |
| 6 | Determination of the effect of probiotic(Saccharomyces cerevisiae)on growth performance and hematological parameters of rabbits显示文摘 | Ezema C Chukwuemeka D E | 2012 | Comparative Clinical Pathology2012，21，1： | 1 |
| 7 | Aortic valve replacement: a safe and durable option in patients with impaired left ventricular systolic function显示文摘 | Chukwuemeka A Rao V Armstrong S | 2006 | Eur J Cardio thoracic Surg2006，29，2： | 1 |
| 8 | Ultrastructural characterization of whole hydrosalpinx from infertile Chinese women显示文摘 | Louis Chukwuemeka Ajonuma Ernest Hung Yu Ng Lin Nga Chan Pak Ham Chow Lai Sin Kung Annie Nga Yin Cheung Lok Sze Ho Christine Briton-Jones Ingrid H. Lok Christopher J. Haines Hsiao Chang Chan | 2005 | Cell Biology International2005，，10： | 1 |
| 9 | Bioproduction of butanol from biomass: from genes to bioreactors显示文摘 | Thaddeus Chukwuemeka Ezeji Nasib Qureshi Hans Peter Blaschek | 2007 | Current Opinion in Biotechnology2007，，3： | 1 |
| 10 | An Empirical Study of Industrial Conflict and Management in Nigeria Local Government System:A Study of Enugu State显示文摘 | CHUKWUEMEKA E O UGWU J ENUGU T O | 2012 | International Journal of Human Resource Studies2012，2，3： | 1 |
| 11 | Short - term low - dose protmfol anaesthesia associated with severe metabolic acidosis显示文摘 | Chukwuemeka ~ Ko R Ralph - Edwards A | 2006 | Anaesth Intensive Care2006，34，5： | 1 |
| 12 | Bioproduction of butanol from bi-omass:From genes to bioreactors显示文摘 | THADDEUS CHUKWUEMEKA EZEJI | 2007 | Current Opinion in Biotechnology2007，18，： | 1 |
| 13 | Burden of gynaecological cancers in developing countries显示文摘Approximately 1:4 of all cancers in women in developing countries(excluding non-melanoma skin cancer) is a gynaecological cancer. The gynaecological cancer burden in developing countries is huge primarily due to the high incidence and mortality of cervical cancer. Cervical cancer accounts for over 60% of the gynaecological cancer burden in developing countries despite being preventable by current technologies. This is due to the absence of effective nationally organized screening programmes in most developing countries. Institution of such programmes, therefore, has the potential to dramatically reduce gynaecological cancer burden in these countries. Subsidized human papilloma virus(HPV) vaccine and HPV typing as well as cheap screening techniques such as visual inspection aided with acetic acid hold the key to effective prevention of cervical cancer in these countries. This is because a significant proportion of patients in developing countries are unable to access and avail themselves of the few available preventive, diagnostic and treatment services because of poverty. Although, advocacy and the political will to invest in the development of human resources and healthcare infrastructure appear critical to gynaecological cancer control and reducing the burden of disease in many developing countries, the proposition assumes that resources are truly available for this investment. This may not be true. Many developing countries rely on foreign aids for developmental programmes and these aids have dwindled significantly with the current global economic meltdown. | Chukwuemeka Anthony Iyoke George Onyemaechi Ugwu | 2013 | World Journal of Obstetrics and Gynecology2013，2，1： | 1 |
| 14 | Molecular Breast Cancer Subtypes in Premenopausal and Postmenopausal African-American Women: Age-Specific Prevalence and Survival显示文摘 | Chukwuemeka U. Ihemelandu LaSalle D. Leffall Robert L. Dewitty Tammey J. Naab Haile M. Mezghebe Kepher H. Makambi Lucile Adams-Campbell Wayne A. Frederick | 2007 | Journal of Surgical Research2007，，1： | 1 |
| 15 | In-plane dead reckoning with knee and waist attched gyroscopes显示文摘 | Liu Zexi Aduba Chukwuemeka Won Chang-Hee | 2011 | Measurement2011，44，： | 1 |
| 16 | PULMONARY EMBOLISM: ROLE OF VENTILATION-PERFUSION SCINTIGRAPHY显示文摘 | Chukwuemeka Onyedika Joseph E. Glaser Leonard M. Freeman | 2012 | Seminars in Nuclear Medicine2012，，： | 1 |
| 17 | In-plane dead reckoning with knee and waist attached gyroscopes显示文摘 | Liu Zexi Aduba Chukwuemeka Won Chang-Hee | 2011 | Measure- ment2011，44，： | 1 |
| 18 | Bacterial isolates from blood cultures of children with suspected septicaemia in Calabar, Nigeria显示文摘 | Martin MM Chukwuemeka EN Anne EA | 2005 | BMC Infect Dis2005，5，110： | 1 |
| 19 | Insights into the characteristics of corrosion products formed on the contact and exposed regions of C1045 steel bolt and nut fasteners exposed to aqueous chloride environments显示文摘This study investigated the characteristics of corrosion products formed on the contact and exposed re-gions of C1045 steel bolt and nut fasteners exposed to aqueous chloride environments.The corroded sur-face morphology,rust compositions,and corrosion kinetics of the bolt specimen were studied by visual observation,optical microscopy(OM),scanning electron microscopy(SEM),X-Ray diffractometry(XRD),micro-Raman,electron probe micro-analyser(EPMA),and potentiodynamic polarization techniques.Re-sults obtained showed a variation in corrosion kinetics,morphology,and composition of the rust layer which were driven by differential aeration and concentration effects.Due to the availability of sufficient dissolved oxygen,the oxyhydroxide compound,lepidocrocite(γ-FeOOH)was detected in the outer rust layer in the exposed region,whereas the inner rust layer was composed of magnetite(Fe_(3)O_(4)).How-ever,the oxygen-deficient contact surface revealed the presence of akaganeite(β-FeOOH)and magnetite(Fe_(3)O_(4))as dominant oxide phases.The most stable phase,goethite(α-FeOOH)was also detected in the rust formed in both regions,though in significantly low amounts.Furthermore,owing to variation in environmental conditions,the amount and density of the rust layer varied in the different regions.The estimated corrosion stability values for the different regions revealed that the corrosion products formed on the steel surfaces were non-protective,suggesting the need for specific surface treatment as a protec-tive measure. | Enobong Felix Daniel Chao Li Changgang Wang Junhua Dong Inime Ime Udoh Peter Chukwuemeka Okafor Dongjiu Zhang Wenan Zhong Sheng Zhong | 2023 | Journal of Materials Science & Technology2023，，4： | 1 |
| 20 | Influence of automobile industrial wastewater on soil quality显示文摘Reuse of industrial wastewater(effluent)for irrigation purpose is a common practice.However,lack of adequate treatment of the effluent can cause soil deterioration,vegetation destruction and contamination of the aquatic environment.These adverse effects necessitated the study of wastewater irrigation in Emene Industrial Layout,Enugu State,Nigeria.Wastewater and soil samples were collected,analyzed and subjected to Analysis of Variance(ANOVA)for Completely Randomized Design(CRD)at 5% probability level using GENSTAT software.The results obtained from the study were compared with FAO soil and water standards.The wastewater analysis suggested that contamination at the untreated stage was very high and results at the treatment level were within the FAO reuse range.The study also found wide variation in chemical status of industrial wastewater treated soil.Almost all the values for the wastewater treated soil were not within the FAO irrigated soil chemical properties standards.This suggests high re-contamination along the open channel(from non-point sources)before reuse.This calls for proper monitoring and treatment of the industrial effluent prior to irrigation application. | Ugwu Samson Nnaemeka Anyadike Chinenye Chukwuemeka Echiegu Emmanuel Nwoke Oji Achuka Ugwuishiwu Boniface | 2014 | International Journal of Agricultural and Biological Engineering2014，7，6： | 1 |
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