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| 1 | Recovery of Iron From High-Iron Red Mud by Reduction Roasting With Adding Sodium Salt显示文摘Red mud is the waste generated during aluminum production from bauxite, containing lots of iron and other valuable metals. In order to recover iron from red mud, the technology of adding sodium carbonate-reduction roasting-magnetic separation to treat high-iron red mud was developed. The effects of sodium carbonate dosage, reduction temperature and reduction time on the qualities of final product and the phase transformations in reduction process were discussed in detail. The results showed that the final product (mass percent), assaying Fe of 90.87% and Al2O3 of 0.95% and metallization degree of 94.28% was obtained at an overall iron recovery of 95.76% under the following conditions of adding 8% sodium carbonate, reduction roasting at 1 050 ℃ for 80 min and finally magnetic separation of the reduced pellets by grinding up to 90% passing 0.074 mm at magnetic field intensity of 0.08 T. The XRD (X-ray diffraction) results indicated that the iron oxides were transformed into metallic iron. Most of aluminum mineral and silica mineral reacted with sodium carbonate during the reduction roasting and formed nonmagnetic materials. | ZHU De-qing, CHUN Tie-jun, PAN Jian, HE Zhen (School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, Hunan, China) | 2012 | Journal of Iron and Steel Research(International)2012，19，8： | 38 |
| 2 | Experimental study on seismic characteristics of typical mortisetenon joints of Chinese southern traditional timber frame buildings显示文摘The seismic characteristics of four typical mortise-tenon joints of Chinese southern traditional timber frame buildings were researched,including Yanwei mortise-tenon joint(including dropping Yanwei mortise-tenon joint),Shizigutou mortise-tenon joint,Ban mortise-tenon joint and Mantou mortise-tenon joint.Experiments on thirteen specimens were carried out.Failure modes,hysteresis curves,skeleton curves and rotational stiffness were studied.The results provided a theoretical basis for seismic research,protection and maintenance of Chinese southern traditional timber frame buildings. | CHUN Qing YUE Zhi PAN JianWu | 2011 | Science China(Technological Sciences)2011，54，9： | 25 |
| 3 | Acute Respiratory Distress Syndrome: Challenge for Diagnosis and Therapy显示文摘 | Chun Pan Ling Liu Jian-Feng Xie Hai-Bo Qiu | 2018 | Chinese Medical Journal2018，，10： | 22 |
| 4 | A Chromosome-Level Genome Assembly of Garlic (Allium sativum) Provides Insights into Genome Evolution and Allicin Biosynthesis显示文摘Garlic,an economically important vegetable,spice,and medicinal crop,produces highly enlarged bulbs and unique organosulfur compounds.Here,we report a chromosome-level genome assembly for garlic,with a total size of approximately 16.24 Gb,as well as the annotation of 57561 predicted protein-coding genes,making garlic the first Allium species with a sequenced genome.Analysis of this garlic genome assembly reveals a recent burst of transposable elements,explaining the substantial expansion of the garlic genome.We examined the evolution of certain genes associated with the biosynthesis of allicin and inulin neoseries-type fructans,and provided new insights into the biosynthesis of these two compounds.Furthermore,a large-scale transcriptome was produced to characterize the expression patterns of garlic genes in different tissues and at various growth stages of enlarged bulbs.The reference genome and large-scale transcriptome data generated in this study provide valuable new resources for research on garlic biology and breeding. | Xiudong Sun Siyuan Zhu Ningyang Li Yi Cheng Jing Zhao Xuguang Qiao Li Lu Shiqi Liu Yanzhou Wang Chan Liu Benping Li Wu Guo Shuang Gao Zemao Yang Fu Li Zheng Zeng Qing Tang Yupeng Pan Mengjiao Guan Jian Zhao Xiaomi ng Lu Huanwe n Meng Zhenlin Han Chun she ng Gao Wenkai Jiang Xing Zhao Shilin Tian Jianguang Su Zhihui Cheng Touming Liu | 2020 | Molecular Plant2020，13，9： | 14 |
| 5 | High-speed colour-converting photodetector with all-inorganic CsPbBr_(3) perovskite nanocrystals for ultraviolet light communication显示文摘Optical wireless communication(OWC)using the ultra-broad spectrum of the visible-to-ultraviolet(UV)wavelength region remains a vital field of research for mitigating the saturated bandwidth of radio-frequency(RF)communication.However,the lack of an efficient UV photodetection methodology hinders the development of UV-based communication.The key technological impediment is related to the low UV-photon absorption in existing silicon photodetectors,which offer low-cost and mature platforms.To address this technology gap,we report a hybrid Sibased photodetection scheme by incorporating CsPbBr_(3) perovskite nanocrystals(NCs)with a high photoluminescence quantum yield(PLQY)and a fast photoluminescence(PL)decay time as a UV-to-visible colourconverting layer for high-speed solar-blind UV communication.The facile formation of drop-cast CsPbBr_(3) perovskite NCs leads to a high PLQY of up to ~73% and strong absorption in the UV region.With the addition of the NC layer,a nearly threefold improvement in the responsivity and an increase of ~25% in the external quantum efficiency(EQE)of the solar-blind region compared to a commercial silicon-based photodetector were observed.Moreover,timeresolved photoluminescence measurements demonstrated a decay time of 4.5 ns under a 372-nm UV excitation source,thus elucidating the potential of this layer as a fast colour-converting layer.A high data rate of up to 34 Mbps in solar-blind communication was achieved using the hybrid CsPbBr_(3)-silicon photodetection scheme in conjunction with a 278-nm UVC light-emitting diode(LED).These findings demonstrate the feasibility of an integrated high-speed photoreceiver design of a composition-tuneable perovskite-based phosphor and a low-cost silicon-based photodetector for UV communication. | Chun Hong Kang Ibrahim Dursun Guangyu Liu Lutfan Sinatra Xiaobin Sun Meiwei Kong Jun Pan Partha Maity Ee-Ning Ooi Tien Khee Ng Omar F.Mohammed Osman M.Bakr Boon S.Ooi | 2019 | Light(Science & Applications)2019，8，1： | 14 |
| 6 | Effects of Cypermethrin on Male Reproductive System in Adult Rats显示文摘Objective To evaluate effects of cypermethrin on the testis histology and testosterone, LH and FSH in adult male Sprague‐Dawley rats. Methods The intact adult male rats were randomly divided into five groups and were treated with cypermethrin at doses of 0, 7.5, 15, 30, or 60 mg/kg per day by oral gavage for 15‐days. After the treatments, serum was collected for hormone assays. The testes, epididymides, seminal vesicles, and prostates were excised and weighed. The right testis was frozen for daily sperm production and the left one was processed for histopathology. Results Daily sperm production decreased significantly in 30 and 60 mg/(kg day) groups. Testicular structure abnormalities included atrophic and distorted seminiferous tubules, deformed and disordered arrangement of germ cells, reduced germ cells, Sertoli cells and Leydig cells, vacuolization and multinucleated formations of spermatids in the cypermethrin‐treated rats. Vacuolization was found in Sertoli cells and the deformed nucleus was noted in Leydig cells. Serum testosterone reduced significantly in 30 and 60 mg/(kg day) groups. Serum FSH increased significantly in 60 mg/(kg day) group. Conclusion Cypermethrin induces impairments of the seminiferous tubules structure and spermatogenesis in the rats. The damages of the male reproductive system may be attributed to the imbalance of circulating testosterone. | LI Yan Fang PAN Chen HU Jin Xia LI Jing XU Li Chun | 2013 | Biomedical and Environmental Sciences2013，26，3： | 13 |
| 7 | Expressions of chromogranin A and cathepsin D in human primary hepatocellular carcinoma显示文摘AIM To determine the expression and clinicalsignificance of chromogranin A and cathepsin Din hepatocellular carcinoma(HCC).METHODS Double immunofluorescence stain-ing techniques combined with laser confocalscanning microscopy(LSCM)was used toinvestigate chromogranin A and cathepsin Dexpressions in 85 HCC patients.RESULTS Cathepsin D was expressed in :3normal liver tissues,while in HCC the stainingshowed regional variation and the fraction ofstrongly stained cells increased as the tumorsbecame less differentiated and usually clinicallymore malignant.Cells which showed strongpositivity for cathepsin D were present in 71/85(83.5%)cases.Strong expression of cathepsinD in cancer cells was related tohistopathological features.They were morecommon in grade 3-4(26/28,92.9%)and grade2(46/53,86.8%)tumors than in grade 1 tumors(1/4,25.0%)(P<0.01).No significantcorrelation was found between age andcathepsin D expression.In patients with positivecathepsin D reaction,the mean age was 52.1±2.8 years(range 32-68 years)and in the groupwith negative reaction,the mean age was 51.3±4.5 years(range 28-71 years).No obvious relationship was observed between CgAexpression in cancer cells and thehistopathological features.The CgA positiverate was 75.0%(3/4)in grade 1,71.7%(38/53)in grade 2,and 71.4%(20/28)in grade 3-4(P>0.05)tumors.The coexpression of CgA andcathepsin D was found by double labeledimmunofluorescence staining techniques.Theprocessing of cathepsin D was disturbed in HCCcells and accumulated in the cells.Cathepsin Dhad proteolytic activity and autocrine mitogeniceffect,suggesting their functions in invasion.These findings demonstrated that the expressionof cathepsin D in HCC had prognostic value.CONCLUSION Chromogranin A and cathepsin Dare expressed in a high proportion of HCC andthe existence of cathepsin D in HCC might berelated to processing of CgA.This is clearly asubject for further studies because of itspotential clinical applications. | Xiao Feng Huang Chun Mei Wang Xiao Wen Dai Zhen Jiang Li Bo Rong Pan Li Bin Yu Bin Qian Li Fang | 2000 | World Journal of Gastroenterology2000，6，5： | 12 |
| 8 | Upgrading and dephosphorization of Western Australian iron ore using reduction roasting by adding sodium carbonate显示文摘The technology of direct reduction by adding sodium carbonate (Na2CO3 ) and magnetic separation was developed to treat Western Australian high phosphorus iron ore. The iron ore and reduced product were investigated by optical microscopy and scanning electron microscopy. It is found that phosphorus exists within limonite in the form of solid solution, which cannot be removed through traditional ways. During reduction roasting, Na2CO3 reacts with gangue minerals (SiO2 and Al2O3 ), forming aluminum silicate-containing phosphorus and damaging the ore structure, which promotes the separation between iron and phosphorus during magnetic separation. Meanwhile, Na2CO3 also improves the growth of iron grains, increasing the iron grade and iron recovery. The iron concentrate, assaying 94.12wt% Fe and 0.07wt% P at the iron recovery of 96.83% and the dephosphorization rate of 74.08%, is obtained under the optimum conditions. The final product (metal iron powder) after briquetting can be used as the burden for steelmaking by an electric arc furnace to replace scrap steel. | De-qing Zhu Tie-jun Chun Jian Pan Li-ming Lu Zhen He | 2013 | International Journal of Minerals,Metallurgy and Materials2013，20，6： | 12 |
| 9 | Typical atmospheric haze during crop harvest season in northeastern China:A case in the Changchun region显示文摘This study presents the mass concentrations of PM_(2.5),O_3,SO_2 and NOxat one urban,one suburban and two rural locations in the Changchun region from September 25 to October 272013. Major chemical components of PM_(2.5)at the four sites were daily sampled and analyzed. Most of daily concentrations of SO_2(7–82 μg/m^3),O_3(27–171 μg/m^3) and NOx(14–213 μg/m^3) were below the limits of the National Ambient Air Quality Standard(NAAQS)in China. However,PM_(2.5)concentrations(143–168 μg/m^3) were 2-fold higher than NAAQS.Higher PM_(2.5)concentrations(~ 150 μg/m^3) were measured during the pre-harvest and harvest at the urban site,while PM_(2.5)concentrations significantly increased from 250 to400 μg m^(-3) at suburban and rural sites with widespread biomass burning. At all sites,PM_(2.5)components were dominated by organic carbon(OC) and followed by soluble component sulfate(SO_4^(2-)),ammonium(NH_4^+) and nitrate(NO_3^-). Compared with rural sites,urban site had a higher mineral contribution and lower potassium(K^+and K) contribution to PM_(2.5).Severe atmospheric haze events that occurred from October 21 to 23 were attributed to strong source emissions(e.g.,biomass burning) and unfavorable air diffusion conditions.Furthermore,coal burning originating from winter heating supply beginning on October 18 increased the atmospheric pollutant emissions. For entire crop harvest period,the Positive Matrix Factorization(PMF) analysis indicated five important emission contributors in the Changchun region,as follows: secondary aerosol(39%),biomass burning(20%),supply heating(18%),soil/road dust(14%) and traffic(9%). | Wei Wei Chen Daniel Q.Tong Mo Dan Shi Chun Zhang Xue Lei Zhang Yue Peng Pan | 2017 | Journal of Environmental Sciences2017，29，4： | 10 |
| 10 | Effect of temperature on the sorption and desorption of perfluorooctane sulfonate on humic acid显示文摘Sorption and desorption of perfluorooctane sulfonate (PFOS) on humic acid at different temperatures were studied. It was found that the sorption process could be modeled with power kinetic equation very well, suggesting that diflusion predominated the sorption of PFOS on the humic acid. The sorption capacity was doubled when the temperature increased from 5 to 35°C, and thermodynamics parameters △G0 was calculated to be -7.11 to -5.04 kJ/mol, △H0 was 14.2 kJ/mol, and △S 0 was 69.5 J/(mol·K), indicating that the sorption was a spontaneous, endothermic, and entropy driven process. Desorption hysteresis occurred at all studied temperatures which suggested that humic acid may be an important sink of PFOS in the environment. | Chengxia Jia, Chun You, Gang Pan State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China. | 2010 | Journal of Environmental Sciences2010，22，3： | 10 |
| 11 | Physiological Correlation of Airway Pressure and Transpulmonary Pressure Stress Index on Respiratory Mechanics in Acute Respiratory Failure显示文摘 | Chun Pan Lu Chen Yun-Hang Zhang Rosario Urbino V Marco Ranieri Hai-Bo Qiu Yi Yang | 2016 | Chinese Medical Journal2016，，14： | 9 |
| 12 | Lentivirus vectors construction of SiRNA targeting interference GPC3 gene and its biological effects on liver cancer cell lines Huh-7显示文摘Objective:To build GPC3 gene short hairpin interference RNA(shRNA)slow virus veclor.observe expression of Huh-7 GPC3 gene in human liver cell line proliferation apoptosis and the effect of GPC3 gene influencing on liver cancer cell growth,and provide theoretical basis for genc therapy of liver cancer.Methods:Hepatocellular carcinoma cell line Huh-7 wsa transfected by a RNA interference technique.GPC3 gene expression in a variety of liver cancer cell lines was detected by fluorescence quantitative PCR.Targeted GPC3 gene seqnences of small interfering RNA(siRNA)PGC-shRNA-GPC3 were restructured.Stable expression cell linse of siRNA were screened and established with the heplp of liposomes(lipofectamine^(TM2000))as carrier transfcetion of human liver cell lines.In order to validate siRNA interference efficiency.GPC3 siRNA mRNA expression was detected after transfection by using RT-PCR and Western blot.The absorbance value of the cells of blank group,untransfection group and transfection group,the cell cycle and cell apoptosis were calculated,and effects of GPC3 gene nn Huh-7 cell proliferation and apoptosis were observed.Results:In the liver cancer cell lines Huh-7 GPC3 gene showed high expression.PGC-shRNA-GPC3 recombinant plasmid was constructde successfully via sequencing validation.Stable recombinant plasmid transfected into liver cancer cell linse Huh-7can obviously inhibit GPC3 mRNA expression level.Conclusions:The targeted GPC3 siRNA can effectively inhibit the expression of GPC3. | Chang-Jiang Lei Chun Yao Qing-Yun Pan Hao-Cheng Long Lei Li Shu-Ping Zheng Cheng Zeng Jian-Bin Huang | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，10： | 8 |
| 13 | Development and Validation of a Model for Predicting Diabetic Nephropathy in Chinese People显示文摘Objective To develop a risk model for predicting later development of diabetic nephropathy(DN)in Chinese people with type 2 diabetes mellitus(T2DM)and evaluate its performance with independent validation.Methods We used data collected from the project‘Comprehensive Research on the Prevention and Control of Diabetes’,which was a community-based study conducted by the Jiangsu Center for Disease Control and Prevention in 2013.A total of 11,771 eligible participants were included in our study.The endpoint was a clear diagnosis of DN.Data was divided into two components:a training set for model development and a test set for validation.The Cox proportional hazard regression was used for survival analysis in men and women.The model’s performance was evaluated by discrimination and calibration.Results The incidence(cases per 10,000 person-years)of DN was 9.95(95%CI;8.66-11.43)in women and 11.28(95%CI;9.77-13.03)in men.Factors including diagnosis age,location,body mass index,high-density-lipoprotein cholesterol,creatinine,hypertension,dyslipidemia,retinopathy,diet control,and physical activity were significant in the final model.The model showed high discrimination and good calibration.Conclusion The risk model for predicting DN in people with T2DM can be used in clinical practice for improving the quality of risk management and intervention. | MIAO Dan Dan PAN En Chun ZHANG Qin SUN Zhong Ming QIN Yu WU Ming | 2017 | Biomedical and Environmental Sciences2017，30，2： | 8 |
| 14 | Morphologies of Al_4Sr Intermetallic Phase and Its Modification Property upon A356 Alloys显示文摘In general,the modification performance of Al-Sr master alloys is primarily dependent upon the morphologies and sizes of the Al_4Sr intermetallic phase.In this paper,the crystal structure,morphologies,sizes,hardness and elastic modulus of Al_4Sr in Al-Sr master alloys prepared from variant processes were studied by means of optical metallurgical microscope,X-ray diffraction(XRD),scanning electron microscopy(SEM),and nanoindentation system.The results revealed that the microstructures and modification performance of the Al_4Sr phase were related to the preparation processes.That is to say,when a 'direct reaction-hot extrusion' process was used,the Al_4Sr phase exhibited a homogeneous distribution in the Al matrix with small size and roundish shapes,which ensured the Al-Sr master alloy wire advantages involving high recovery,good reproducibility,no delitescence of modification,no corrosion on equipments,and good workability.However,in the case of the traditional 'direct reaction' process,the Al4Sr phase was in large size with shapes of rectangular stripe and plates,which limited the Sr content increasing due to the brittleness of the Al-Sr alloy.It was also found that the morphology and size of the Al_4Sr phases changed during heat treatment at high temperature up to 600 ℃. | Chengwei Liao Jianchun Chun Yang Li Rui Tu Chunxu Pan | 2012 | Journal of Materials Science & Technology2012，28，6： | 7 |
| 15 | Effects of Propofol on Respiratory Drive and Patient-ventilator Synchrony during Pressure Support Ventilation in Postoperative Patients: A Prospective Study显示文摘 | Ling Liu Ai-Ping Wu Yi Yang Song-Qiao Liu Ying-Zi Huang Jian-Feng Xie Chun Pan Cong-Shan Yang Hai-Bo Qiu | 2017 | Chinese Medical Journal2017，，10： | 7 |
| 16 | 挑战与希望:AI 2.0时代从大数据到知识(英文)显示文摘本文对大数据时代人工智能领域近期出现的若干理论和技术进展进行了综述。我们认为,将数据驱动机器学习方法与人类的常识先验与隐式直觉有效结合起来,可实现可解释、更鲁棒和更通用的人工智能。AI 2.0时代大数据人工智能具体表现为:从浅层计算到深度神经推理;从单纯依赖于数据驱动的模型到数据驱动与知识引导相结合学习;从领域任务驱动智能到更为通用条件下的强人工智能(从经验中学习)。下一代人工智能(AI 2.0)将改变计算本身,将大数据转变为知识以支持人类社会作出更好决策。 | Yue-ting ZHUANG Fei WU Chun CHEN Yun-he PAN | 2017 | Frontiers of Information Technology & Electronic Engineering2017，18，1： | 6 |
| 17 | Expression of proliferating cell nuclear antigen in polyps from large intestine显示文摘Coloncancerhasahighincidenceintheworld,especialyinWesterncountries,andtheincidenceisalsoincreasinginChinainrecentyears.Toredu... | LUO Yu Qin 1, MA Lian Sheng 2, ZHAO Yi Ling 3, WU Kai Chun 4, PAN Bo Rong 5 and ZHANG Xue Yong 4 | 1999 | World Journal of Gastroenterology1999，5，2： | 6 |
| 18 | Histone Deacetylase HDA9 and WRKY53 Transcription Factor Are Mutual Antagonists in Regulation of Plant Stress Response显示文摘Epigenetic regulation of gene expression is important for plant adaptation to environm ental changes.Previous results showed that Arabidopsis RPD3-like histone deacetylase HDA9 is known to function in repressing plant response to stress in Arabidopsis.However,how HDA9 targets to specific chromatin loci and controls gene expression netw orks involved in plant response to stress remains largely unclear.Here,we show that HDA9 represses stress tolerance response by interacting with and regulating the DNA binding and transcriptional activity of WRKY53,which functions as a high-hierarchy positive regulator of stress response.We found that WRKY53 is post-translationally modified by lysine acetylation at multiple sites,some of which are removed by HDA9,resulting in inhibition of WRKY53 transcription activity.Conversely,WRKY53 negatively regulates HDA9 histone deacetylase activity.Collectively,our results indicate that HDA9 and WRK53 are reciprocal negative regulators of each other's activities,illustrating how the functional interplay between a chromatin regulator and a transcription factor regulates stress tolerance in plants. | Yu Zheng Jingyu Ge Chun Bao Wenwen Chang Jingjing Liu Jingjie Shao Xiaoyun Liu Lufang Su Lei Pan Dao-Xiu Zhou | 2020 | Molecular Plant2020，13，4： | 6 |
| 19 | Reemergent Cases of COVID-19—Xinfadi Wholesales Market,Beijing Municipality,China,June 11,2020显示文摘No new local coronavirus disease 2019(COVID-19)cases were reported in Beijing for over 56 days before the reemergent COVID-19 cases that were reported on June 11,2020,and more than 200 confirmed cases have been reported as of June 20 in Beijing.All confirmed COVID-19 cases were associated with Xinfadi Wholesale Market.Here,we reported the phylogenetic characteristics of the COVID-19 viruses(also known as severe acute respiratory syndrome coronavirus 2,SARS-CoV-2,and human coronavirus 2019,HCoV-19)sequenced from the clinical specimens of 2 human cases and 1 environmental sample. | Wenjie Tan Peihua Niu Xiang Zhao Yang Pan Yong Zhang Lijuan Chen Li Zhao Yanhai Wang Dayan Wang Jun Han George FGao Chun Huang Wenbo Xu Guizhen Wu | 2020 | China CDC weekly2020，2，27： | 6 |
| 20 | An ion-imprinted polymer supported by attapulgite with a chitosan incorporated sol-gel process for selective separation of Ce(Ⅲ)显示文摘The surface ion-imprinting concept and chitosan incorporated sol-gel process were applied to the synthesis of a new attapulgitesupported polymer for selective separation of Ce(Ⅲ) from aqueous solution.The imprinting mechanism of prepared ion-imprinted polymer were discussed with the Characteristics of FT-IR and SEM.Results from the experiments of adsorption capacity and selectivity suggested that ion-imprinted polymer offered a fast kinetics for the adsorption of Ce(Ⅲ) under the optimum conditions. Its maximum adsorption capacity was 38.02 mg/g,and the selective recognition towards Ce(Ⅲ) was much higher than that of the non-imprinted polymer and attapulgite.The prepared functional polymer was shown to be promising for selective separation and enrichment of trace Ce(Ⅲ) in environmental samples. | Chun Xiang Li Jian Ming Pan Jie Gao Yong Sheng Yan Gan Qing Zhao | 2009 | Chinese Chemical Letters2009，20，8： | 6 |
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