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| 1 | A discussion on the upper limit of maturity for gas generation by marine kerogens and the utmost of gas generative potential:Taking the study on the Tarim Basin as an example显示文摘The experimental data yielded by Rock-Eval pyrolysis, kerogen atomic H/C, Py-GC and gold-tube sealing thermal simulation on the marine Cambrian-Ordovician source rock from the Tarim Basin revealed that the upper limit of maturity for natural gas generation or the 'deadline of gas generation' for marine types I and II kerogens is equal to 3.0% of vitrinite reflectance (Ro); while the 'deadline of gas generation' for type III kerogens typically like coals is as high as 10% Ro. Thus, different organic matter has obviously different utmost maturities for gas generation. The mass-balance calculation by kerogen elements showed that when Ro>1.5%, the utmost amount of gas generation for the marine type II kerogen is less than 185 m3/t TOC, accounting for less than 30% of its total hydrocarbon generative potential; when Ro>2.0%, it becomes 110 m3/t TOC, less than 20% of the total hydrocarbon generative potential. The amount of the gas generative potential obtained by Rock-Eval is only around one tenth of the calculated value by the mass balance of kerogen elements at the same thermal evolutionary stage, while those by Py-GC and gold-tube sealing simulation are intervenient between the above two. The utmost of gas generative potential at the over 1.3% Ro stage is around 60―90 m3/t TOC, therefore, the amount of gas generation obtained by Rock-Eval is the minimum of gas generative potential, while that by the mass-balance calculation of kerogen elements is the maximum that the actual amount of gas generation should not exceed. | CHEN JianPing ZHAO WenZhi XIAO ZhongYao ZHANG ShuiChang DENG ChunPing SUN YongGe WANG ZhaoMing | 2007 | Chinese Science Bulletin2007，52，A01： | 8 |
| 2 | Formation mechanism of condensates, waxy and heavy oils in the southern margin of Junggar Basin, NW China显示文摘It is a challenge to determine the source and genetic relationship of condensate, waxy and heavy oils in one given complicated petroliferous area, where developed multiple sets of source rocks with different maturity and various chemical features.The central part of southern margin of Junggar Basin, NW China is such an example where there are condensates, light oils, normal density oils, heavy crude oils and natural gases. The formation mechanism of condensates has been seriously debated for long time;however, no study has integrated it with genetic types of waxy and heavy oils. Taking the central part of southern margin of Junggar Basin as a case, this study employs geological and geochemical methods to determine the formation mechanism of condensates,waxy and heavy oils in a complicated petroliferous area, and reveals the causes and geochemical processes of the co-occurrence of different types of crude oils in this region. Based on detailed geochemical analyses of more than 40 normal crude oils, light oils,condensates and heavy oils, it is found that the condensates are dominated by low carbon number n-alkanes and enriched in light naphthenics and aromatic hydrocarbons. Heptane values of these condensates range from 19% to 21%, isoheptane values from1.9 to 2.1, and toluene/n-heptane ratios from 1.5 to 2.0. The distribution of n-alkanes in the condensates presents a mirror image with high density waxy crude oils and heavy oils. Combined with the oil and gas-source correlations of the crude oils, condensates and natural gas, it is found that the condensates are product of evaporative fractionation and/or phase-controlled fractionation of reservoir crude oils which were derived from mature Cretaceous lacustrine source rocks in the relatively early stage. The waxy oils are the intermediate products of evaporative fractionation and/or phase-controlled fractionation of reservoir crude oils, while the heavy oils are in-situ residuals. Therefore, evaporative fractionation and/or phase-controlled fractionation would account for the formation of the condensate, light oil, waxy oil and heavy oil in the central part of southern margin of Junggar Basin, resulting in a great change of the content in terms of light alkanes, naphthenics and aromatics in condensates, followed by great uncertainties of toluene/n-heptane ratios due to migration and re-accumulation. The results suggest that the origin of the condensate cannot be simply concluded by its ratios of toluene/n-heptane and n-heptane/methylcyclohexane on the Thompson's cross-plot, it should be comprehensively determined by the aspects of geological background, thermal history of source rocks and petroleum generation,physical and chemical features of various crude oils and natural gas, vertical and lateral distribution of various crude oils in the study area. | CHEN JianPing DENG ChunPing WANG XuLong NI YunYan SUN YongGe ZHAO Zhe LIAO JianDe WANG PeiRong ZHANG DiJia LIANG DiGang | 2017 | Science China Earth Sciences2017，60，5： | 3 |
| 3 | miRNA-dysregulation associated with tenderness variation induced by acute stress in Angus cattle显示文摘miRNAs are a class of small, single-stranded, non-coding RNAs that perform post-transcriptional repression of target genes by binding to 3' untranslated regions. Research has found that miRNAs involved in the regulation of many metabolic processes. Here we uncovered that the beef quality of Angus cattle sharply diversified after acute stress. By performing miRNA microarray analysis, 13 miRNAs were significantly differentially expressed in stressed group compared to control group. Using a bioinformatics method, 135 protein-coding genes were predicted as the targets of significant differentially expressed miRNAs. Gene Ontology (GO) term and Ingenuity Pathway Analysis (IPA) mined that these target genes involved in some important pathways, which may have impact on meat quality and beef tenderness. | Chunping Zhao Fei Tian Ying Yu George Liu Linsen Zan M Scott Updike Jiuzhou Song | 2012 | Journal of Animal Science and Biotechnology2012，3，2： | 2 |
| 4 | Studies on polypyrrole modified nafion membrane for vanadium redox flow battery显示文摘 | Jie Zeng Chunping Jiang Yaohui Wang Jinwei Chen Shifu Zhu Beijun Zhao Ruilin Wang | 2007 | Electrochemistry Communications2007，，3： | 1 |
| 5 | Studies on polypyrrole modified nafion membrane for vanadium redox flow battery显示文摘 | Jie Zeng Chunping Jiang Yaohui Wang Jinwei Chen Shifu Zhu Beijun Zhao Ruilin Wang | 2007 | Electrochemistry Communications2007，，3： | 1 |
| 6 | Either transepidermal water loss rates or stratum corneum hydration levels can predict quality of life in children with atopic dermatitis显示文摘Importance:Patients with atopic dermatitis(AD)display compromised epidermal barrier and suffer from poor quality of life.We hypothesized that quality of life could reflect in the changes in the epidermal barrier function.Objective:To determine whether the epidermal barrier function correlates with the severity of pruritus and/or life quality in children with AD.Methods:A total of 120 children,aged 0-12 years,with moderate AD were enrolled.Children were topically treated with topical corticosteroids(TCS)and an emollient for 2 weeks.The Eczema Area and Severity Index(EASI),visual analogue scale(VAS)for pruritus severity,the Infant’s Dermatitis Quality of Life Index(IDQOL)and the Children’s Dermatology Life Quality Index(CDLQI)were evaluated.Transepidermal water loss(TEWL)rates,stratum corneum(SC)hydration,and skin surface pH were measured.Correlations of epidermal barrier function with pruritus,life quality,and EASI were determined.Results:Following 2-week treatments,significant improvements were observed in EASI,TEWL,SC hydration,the VAS of pruritus,as well as DQOL(P<0.001 for all).TEWL positively,while SC hydration negatively correlated with VAS pruritus,DQOL,and EASI(P<0.001).Interpretation:Both TEWL and SC hydration levels can serve as indicators of the severity of pruritus and quality of life in children with AD. | Shan Wang Chunping Shen Mutong Zhao Lei Jiao Jing Tian Yang Wang Lin Ma Mao-Qiang Mao-Qiang Man | 2021 | Pediatric Investigation2021，5，4： | 1 |
| 7 | The Role of Hypoxia Inducible Factor-1 in Hepatocellular Carcinoma显示文摘 | Dongjun Luo Zhongxia Wang Junyi Wu Chunping Jiang Junhua Wu Jingmin Zhao | 2014 | BioMed Research International2014，，： | 1 |
| 8 | Studies on polypyrrole modified Nafion membrane for vanadium redox flow battery显示文摘 | Zeng Jie Jiang Chunping Wang Yaohui Chen Jinwei Zhu Shifu Zhao Beijun Wang Ruilin | | 0，，： | 1 |
| 9 | Graph designs fornine graphs with six vertices and nine edges显示文摘 | Kang Qingde Zhao Hongtao Ma Chunping | 2008 | Ars Combinato-ria2008，88，： | 1 |
| 10 | G-decompositionofλKv,where G has six vertices and nine edges显示文摘 | Kang Qingde Ma Chunping Zhao Hongtao | 2010 | ArsCombinatoria2010，94，： | 1 |
| 11 | IL-6R blockade by chikusetsusaponin IVa butyl ester inhibits Th17 cell differentiation and ameliorates collagen-induced arthritis显示文摘Interleukin(IL)-6 is central to the pathogenesis of rheumatoid arthritis(RA).1 IL-6 receptor(IL-6R)blockade is an effective treatment strategy for RA based on the clinical efficacy of tocilizumab.However,serious infections are the most frequent adverse events associated with long-term monotherapy with tocilizumab,an exogenous biomacromolecule.2 Novel small-molecule IL-6R inhibitors with fewer deleterious side effects could therefore have potential as RA treatments.We previously identified chikusetsusaponin IVa butyl ester(CS)as a natural small-molecule IL-6R antagonist.3 Here,we assessed the effects of CS on a mouse model of collagen-induced arthritis(CIA)to evaluate its therapeutic potential against RA.The results showed that CS ameliorated arthritis in CIA mice by inhibiting T-helper 17(Th17)cell differentiation and could serve as a novel agent for treating RA. | Jie Yang Yuanyuan Ling Di Hua Chenglei Zhao Xiaoyan Sun Xueting Cai Jiao Chen Chunping Hu Peng Cao | 2021 | Cellular & Molecular Immunology2021，18，6： | 1 |
| 12 | Progress on rock mechanics research of Beishan granite for geological disposal of high-level radioactive waste in China显示文摘The mechanical behavior of host rock for a deep geological repository of high-level radioactive waste plays a key role in ensuring the isolation function of host rock as a natural barrier under the multi-field coupling environment.For a better understanding of granite in China's Beishan pre-selected area for geological disposal of high-level radioactive waste,a series of investigations were carried out on in-situ stress field of rock mass at depth,strength and deformation characteristics of rocks under different stress and temperature conditions,and rock boreability and adaptability to Tunnel Boring Machine(TBM)technology.The results indicate that Beishan granite shows typical characteristics as a hard and brittle rock with a quite low permeability,and it is favorable to geological disposal.Meanwhile,a new rock mass suitability evaluation system was proposed,and the rock mass mainly composed of Beishan granite was proven to be suitable for geological disposal.Besides,the constructability of Beishan granite at engineering scale was tested and verified through field tests in the Beishan Exploration Tunnel(BET).Here,we summarize the main outcomes of rock mechanics research on Beishan granite in the past years and introduced the current progress of Beishan underground research laboratory(URL)for geological disposal. | Liang Chen Xingguang Zhao Jian Liu Hongsu Ma Chunping Wang Haiyang Zhang Ju Wang | 2023 | Rock Mechanics Bulletin2023，2，3： | 1 |
| 13 | Studies on polypyrrole modified Nafion membrane for vanadium redox flow battery显示文摘 | Zeng Jie Jiang Chunping Wang Yaohui Chen Jinwei Zhu Shifu Zhao Beijun WangRuilin | 2008 | Electrochemistry Communications2008，10，3： | 1 |
| 14 | Preparation of poly ( lactic acid ) and modified starch composites 显示文摘 | CHUNPING O WANG Y ZHAO N P | 2012 | Polym Bull2012，68，7： | 1 |
| 15 | Degradable nanocatalyst enables antitumor/antibacterial therapy and promotion of wound healing for diabetes via self-enhanced cascading reaction显示文摘Diabetic patients often have problems such as residual tumor and wound infection after tumor resection,causing severe clinical problems.It is urgent to develop effective therapies to reach oncotherapy/antiinfection/promotion of wound healing combined treatment.Herein,we propose CS/MnO_(2)-GO_x (CMGO_x)nanocatalysts for the specific catalytic generation of ~·OH to inhibit tumors and bacteria in a hyperglycemic environment.The good biocompatible chitosan (CS),as a carrier for the catalyst,exhibits excellent antibacterial effect as well as promotes wound healing.Glucose oxidase (GO_x) is loaded on the surface of CS nanoparticles to generate H_(2)O_(2) and gluconic acid by consuming glucose (starvation therapy,ST) and O_(2).The MnO_(2) depletes glutathione (GSH) to produce Mn^(2+),amplifying oxidative stress and further promoting the activity of Mn^(2+)-mediated Fenton-like reaction to produce~·OH (chemodynamic therapy,CDT)in weak acidic environment.Moreover,the produced gluconic acid lowers the p H of the environment,enhancing chemodynamic therapy (ECDT).The tumor cells and bacteria are efficiently eliminated by the synergistic effect of ST and ECDT.The MnO_(2) nanoparticles at neutral environment decomposes H_(2)O_(2) into O_(2),which cooperate with CS to promote healing.The self-enhanced cascade reaction of CMGO_x in situ exhibits excellent effects of antitumor/antibacterial therapy and promotion of wound healing,offering a promising integrated treatment for diabetic patients after tumor surgical resection. | Xiang Wang Cheng Ding Ziwen Zhang Chunlin Li Dongmiao Cao Linjing Zhao Guoying Deng Yu Luo Chunping Yuan Jie Lu Xijian Liu | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
| 16 | Construction of phosphorus-doping with spontaneously developed selenium vacancies: Inducing superior ion-diffusion kinetics in hollow Cu_(2)Se@C nanospheres for efficient sodium storage显示文摘Achieving high-efficiency sodium storage in metal selenides is still severely constrained in consideration of their inferior electronic conductivity and inadequate Na^(+)insertion pathways and active sites.Heteroatom doping accompanied by spontaneously developed lattice defects can effectively tune electronic structure of metal selenides,which give a strong effect to motivate fast charge transfer and Na^(+)accessibility.Herein,we finely designed and successfully constructed a fascinating phosphorus-doped Cu_(2)Se@C hollow nanosphere with abundant vacancy defects(Cu_(2)P_(x)Se_(1-x)@C)through a combination strategy of selenization of Cu_(2)O nanosphere template,self-polymerization of dopamine,and subsequent phosphorization treatment.Such exquisite composite possesses enriched active sites,superior conductivity,and sufficient Na^(+)insertion channel,which enable much faster Na^(+)diffusion rates and more remarkable pseudocapacitive features,Satisfyingly,the Cu_(2)P_(x)Se_(1-x)@C composites manifest the supernormal sodium-storage capabilities,that is,a reversible capacity of 403.7 mA h g^(-1) at 1.0 A g^(-1) over 100 cycles,and an ultrastable cyclic lifespan over 1000 cycles at 20.0 A g^(-1) with a high capacity-retention of about249.7 mA h g^(-1).The phase transformation of the Cu_(2)P_(x)Se_(1-x)@C involving the intercalation of Na^(+)into Cu_(2)Se and the following conversion of NaCuSe to Cu and Na2Se were further demonstrated through a series of ex-situ characterization methods.DFT results demonstrate that the coexistence of phosphorusdoping and vacancy defects within Cu_(2)Se results in the reduction of Na^(+)adsorption energy from-1.47to-1.56 eV improving the conductivity of Cu_(2)Se to further accelerate fast Na^(+)mobility. | Xiaoqing Ma Yadong Li Xiaojiang Long Hong-chuan Luo Chunping Xu Guangzhao Wang Wenxi Zhao | 2023 | Journal of Energy Chemistry2023，，2： | 0 |
| 17 | Intracavity spatiotemporal metasurfaces显示文摘Optical metasurfaces are endowed with unparallel flexibility to manipulate the light field with a subwavelength spatial resolution.Coupling metasurfaces to materials with strong optical nonlinearity may allow ultrafast spatiotemporal light field modulation.However,most metasurfaces demonstrated thus far are linear devices.Here,we experimentally demonstrate simultaneous spatiotemporal laser mode control using a single-layer plasmonic metasurface strongly coupled to an epsilon-near-zero(ENZ)material within a fiber laser cavity.While the geometric phase of the metasurface is utilized to convert the laser’s transverse mode from a Gaussian beam to a vortex beam carrying orbital angular momentum,the giant nonlinear saturable absorption of the ENZ material enables pulsed laser generation via the Q-switching process.The direct integration of a spatiotemporal metasurface in a laser cavity may pave the way for the development of miniaturized laser sources with tailored spatial and temporal profiles,which can be useful for numerous applications,such as superresolution imaging,high-density optical storage,and three-dimensional laser lithography. | Wenhe Jia Chenxin Gao Yongmin Zhao Liu Li Shun Wen Shuai Wang Chengying Bao Chunping Jiang Changxi Yang Yuanmu Yang | 2023 | Advanced Photonics2023，5，2： | 0 |
| 18 | A meta-analysis on the effects of probiotics on the performance of pre-weaning dairy calves显示文摘Background:Probiotics have been used in livestock production for many years,but information on their benefits during the early life of calves is inconsistent.This study aimed to assess the effects of probiotics on the performance of pre-weaning dairy calves and identify the factors influencing their effect sizes.Results:Forty-nine studies were selected for meta-analysis based on the inclusion and exclusion criteria.The study qualities were evaluated using a predefined risk assessment tool following GRADE guidelines.Meta-analysis results showed that probiotics increased the growth performance(body weight by 1.988 kg and average daily gain by40.689 g/d),decreased digestibility and feed efficiency(feed conversion rate by 0.073),altered rumen parameter(decreased acetate by 2.815 mmol/L and increased butyrate by 0.788 mmol/L),altered blood parameter(decreased AST by 4.188 U/L,increased BHBA by 0.029 mmol/L and IgG by 0.698 g/L),increased faecal parameter(faecal bacteria counts by 0.680 log10CFU/g),based on the strict criteria(P_(SMD)<0.05,I^(2)<50%).Additionally,probiotics increased digestibility and feed efficiency(starter dry matter intake by 0.034 kg/d and total dry matter intake by 0.020 kg/d),altered blood parameter(increased IgA by 0.313 g/L,IgM by 0.262 g/L and total antioxidant capacity by 0.441 U/mL,decreased MDA by 0.404 nmol/mL),decreased faecal parameter(faecal score by 0.052),based on the loose criteria(P_(SMD)<0.05,I^(2)>50%).Regression and sub-group analyses showed that probiotic strains,supplementation dosage,and methods significantly affected the performance of calves.The probiotics supplied with more than 9.5 log10CFU/d significantly increased IgA and IgM contents(P_(SMD)<0.05).Additionally,the compound probiotics significantly increased TDMI,IgA,and IgM(P_(SMD)≤0.001).Furthermore,probiotics supplemented in liquid(whole milk or milk replacer)significantly increased TDMI and decreased faecal score(P_(SMD)<0.05),while in whole milk,they significantly increased body weight,IgA,and IgM(P_(SMD)<0.001).Conclusions:Probiotics could improve the growth performance,feed intake and efficiency,rumen fermentation,immune and antioxidant capacity,and health of pre-weaning calves.However,the effect sizes were related to the dosage,composition,and supplementation methods of probiotics. | Liyun Wang Honghong Sun Haixu Gao Yaohui Xia Linsen Zan Chunping Zhao | 2023 | Journal of Animal Science and Biotechnology2023，14，3： | 0 |
| 19 | Association mapping and domestication analysis to dissect genetic improvement process of upland cotton yield-related traits in China显示文摘Background: Cotton fiber yield is a complex trait,which can be influenced by multiple agronomic traits.Unravelling the genetic basis of cotton fiber yield-related traits contributes to genetic improvement of cotton.Results: In this study,503 upland cotton varieties covering the four breeding stages(BS1–BS4,1911–2011)in China were used for association mapping and domestication analysis.One hundred and forty SSR markers significantly associated with ten fiber yield-related traits were identified,among which,29 markers showed an increasing trend contribution to cotton yield-related traits from BS1 to BS4,and 26 markers showed decreased trend effect.Four favorable alleles of 9 major loci(R^(2)≥3)were strongly selected during the breeding stages,and the candidate genes of the four strongly selected alleles were predicated according to the gene function annotation and tissue expression data.Conclusions :The study not only uncovers the genetic basis of 10 cotton yield-related traits but also provides genetic evidence for cotton improvement during the cotton breeding process in China. | GUO Chunping PAN Zhenyuan YOU Chunyuan ZHOU Xiaofeng HUANG Cong SHEN Chao ZHAO Ruihai YANG Qingyong ZHU Longfu SHAHZAD Raheel MENG Fande LIN Zhongxu NIE Xinhui | 2021 | Journal of Cotton Research2021，4，2： | 0 |
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