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	题名	作者	年代	出处	被引量
1	Assessment of neovascularization within carotid plaques in patients with ischemic stroke显示文摘AIM:To assess neovascularization within human ca-rotid atherosclerotic soft plaques in patients with isch-emic stroke.METHODS:Eighty-one patients with ischemic stroke and 95 patients without stroke who had soft athero-sclerotic plaques in the internal carotid artery were studied.The thickest soft plaque in each patient was examined using contrast-enhanced ultrasound.Time-intensity curves were collected from 5 s to 3 min after contrast injection.The neovascularization within the plaques in the internal carotid artery was evaluated using the ACQ software built into the scanner by 2 of the experienced investigators who were blinded to the clinical history of the patients.RESULTS:Ischemic stroke was present in 7 of 33 patients(21%) with grade Ⅰ plaque,in 14 of 51 pa-tients(28%) with grade Ⅱ plaque,in 26 of 43 patients(61%) with grade Ⅲ plaque,and in 34 of 49 patients(69%) with grade Ⅳ plaque(P < 0.001 comparing grade Ⅳ plaque with grade I plaque and with grade Ⅱ plaque and P = 0.001 comparing grade Ⅲ plaque with grade Ⅰ plaque and with grade Ⅱ plaque).Analysis of the time intensity curves revealed that patients with ischemic stroke had a significantly higher intensity of enhancement(IE) than those without ischemic stroke(P < 0.01).The wash-in time(WT) of plaque was signifi-cantly shorter in stroke patients(P < 0.05).The sensi-tivity and specificity for IE in the plaque were 82% and 80%,respectively,and for WT were 68% and 74%,respectively.There was no significant difference in the peak intensity or time to peak between the 2 groups.CONCLUSION:This study shows that the higher the grade of plaque enhancement,the higher the risk of ischemic stroke.The data suggest that the presence of neovascularization is a marker for unstable plaque.	Wilbert S Aronow Chandra K Nair David Cosgrove	2010	World Journal of Cardiology2010，2，4：	29
2	Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) - Update 2008显示文摘	M Claudon D Cosgrove T Albrecht L Bolondi M Bosio F Calliada J.-M Correas K Darge C Dietrich M D’Onofrio D Evans C Filice L Greiner K J?ger N Jong E Leen R Lencioni D Lindsell A Martegani S Meairs C Nols?e F Piscaglia P Ricci G Seidel B Skjoldbye L Solbia	2008	Ultraschall in Med2008，，01：	4
3	Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) - Update 2008显示文摘	M Claudon D Cosgrove T Albrecht L Bolondi M Bosio F Calliada J.-M Correas K Darge C Dietrich M D'Onofrio D Evans C Filice L Greiner K J?ger N Jong E Leen R Lencioni D Lindsell A Martegani S Meairs C Nols?e F Piscaglia P Ricci G Seidel B Skjoldbye L Solbia	2008	Ultraschall in Med2008，，01：	3
4	Effects of antibiotcs nosoeomial epidemiology of vaneomyein-resistant enterococci显示文摘	Harbarth S Cosgrove S Carmeli Y	2002	Antimierob Agents Chemother2002，46，6：	1
5	Location of language in the cortex: a Comparison between functional MR imaging and elec- trocortical stimulation显示文摘	Fitzgerald DB Cosgrove GR Rormer S	1997	AJNR Am J Neuroradiol1997，18，8：	1
6	Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS) - Update 2008显示文摘	M Claudon D Cosgrove T Albrecht L Bolondi M Bosio F Calliada J.-M Correas K Darge C Dietrich M D’Onofrio D Evans C Filice L Greiner K J?ger N Jong E Leen R Lencioni D Lindsell A Martegani S Meairs C Nols?e F Piscaglia P Ricci G Seidel B Skjoldbye L Solbia	2008	Ultraschall in Med2008，，01：	1
7	Two endogenous proteins that induce cell wall extension in plants 显示文摘	McQueen-Mason S J Durachko D M Cosgrove D J	1992	The Plant Cell1992，4，：	1
8	Update on the role of triglycerides as a risk factor for coronary heart disease显示文摘	Miller M Cosgrove B Havas S	2002	Curr Atheroscler Rep2002，4，6：	1
9	Safety profile and efficacy of botulinum toxin A (Dysport) in children with muscle spasticity显示文摘	Bakheit AMO Severa S Cosgrove A	2001	Dev Med Child Neural2001，43，：	1
10	A mul- ticenter intervention to prevent catheter-associated blood stream infeetions 显示文摘	Warren D K Cosgrove S E Diekema D J	2006	Infect Control Hosp Epide-miol2006，27，7：	1
11	Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgicalsite infection显示文摘	Engemann J J Carmeli Y Cosgrove S E	2003	Clin Infect Dis2003，36，5：	1
12	Cavernous angiomas of the spinal cord显示文摘	Cosgrove GR Bertrand G Fontaine S	1988	Neurosurg1988，68，1：	1
13	Is anterior leaflet repair always necessary in repair of bileaflet mitral valve prolapse 显示文摘	Gillinov AM Cosgrove DM 3rd Wahl S	1999	Ann Thorac Surg1999，68，3：	1
14	Expansin mode of action on cell walls:analysis of wall hydrolysis stress relaxation and binding显示文摘	Mason M S Cosgrove D J	1995	Plant Physiology1995，107，：	1
15	Location of language in the cortex: a comparison between functional MR imaging and electrocortical stimulation显示文摘	FitzGerald DB Cosgrove GR Ronner S	1997	AJNR Am J Neuroradiol1997，18，：	1
16	Nutrition in adult and childhood cancer:role of carcinogens and anti-carcinogens显示文摘	Mosby T T Cosgrove M Sarkardei S		0，，10：	1
17	Update in the diagnosis and management of pulmonary vasculitis显示文摘	Frankel S K Cosgrove G P Fischer A	2006	Chest2006，129，2：	1
18	Electrical conductivity and density of molten cryolite with additives显示文摘	Edwards J D Taylor C S Cosgrove L A	1953	Jour- nal of the Electrochemical Society1953，100，11：	1
19	Health and economic outcomes of the emergenece of third-generation cephalosporin resistance in Enterobacter species显示文摘	Cosgrove S E Kaye K S Eliopoulous G M	2002	Arch Intern Med2002，162，2：	1
20	Human tobacco smokers in early abstinence have higher levels of beta2 nicotinic acetyleholine receptors than nonsmokers 显示文摘	Staley JK Kriaiman-Sarin S Cosgrove KP	2006	J Neurosci2006，26，：	1

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