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| 1 | Active power regulation of wind power systems through demand response显示文摘With the specific characteristics of low-carbon intensity and economy,wind power has been widely promoted around the world.Due to the variable and intermittent nature of wind power production,the system has to frequently redispatch generators in order to ensure the effective use of wind power whilst maintaining system security.In this way,traditional generation costs are increased and the social benefit of wind power decreases indirectly.In this paper,a new regulation strategy based on power flow tracing was proposed,taking advantage of a comfort-constrained demand response strategy to follow the fluctuations of wind farm output,with the remaining imbalance of active power compensated by traditional generators.Examples showed that compared with conventional regulation,demand response could reduce the gross operating costs of the system,and the rapid response could help maintaining system stability in case of contingency.The strategy in this paper also applies to other large-scale integration problems associated with renewable energy resources which display short-term production variability. | MIAO WeiWei JIA HongJie WANG Dan PARKINSON Simon CRAWFORD Curran DJILALI Ned | 2012 | Science China(Technological Sciences)2012，55，6： | 24 |
| 2 | Clonal Characterization of Bone Marrow Derived Stem Cells and Their Application for Bone Regeneration显示文摘Tissue engineering allows the design of functionally active cells within supportive bio-scaffolds to promote the development of new tissues such as cartilage and bone for the restoration of pathologically altered tissues.However,all bone tissue engineering applications are limited by a shortage of stem cells.The adult bone marrow stroma contains a subset of nonhematopoietic cells referred to as bone marrow mesenchymal stem cells(BMSCs).BMSCs are of interest because they are easily isolated from a small aspirate of bone marrow and readily generate single-cell-derived colonies.These cells have the capacity to undergo extensive replication in an undifferentiated state ex vivo.In addition,BMSCs have the potential to develop either in vitro or in vivo into distinct mesenchymal tissues,including bone,cartilage,fat,tendon,muscle,and marrow stroma.Thus,BMSCs are an attractive cell source for tissue engineering approaches.However,BMSCs are not homo-geneous and the quantity of stem cells decreases in the bone marrow in aged population.A sequential loss of lineage differentiation potential has been found in the mixed culture of bone marrow stromal cells due to a heterogenous popu-lation.Therefore,a number of studies have proposed that homogenous bone marrow stem cells can be generated from clonal culture of bone marrow cells and that BMSC clones have the greatest potential for the application of bone regeneration in vivo. | Shobha Mareddy Ross Crawford | 2010 | International Journal of Oral Science2010，2，3： | 15 |
| 3 | 我国农村居民的红细胞脂肪酸、血浆脂质与心血管疾病显示文摘对我国49个县的心血管疾病(CVD,包括冠心病、高血压心脏病和脑卒中)死亡率和4900例35~64岁成年男女的膳食进行了调查,并测定了血浆脂质[总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和甘油三酸酯(TG)]的含量,结果指出:1.和西方国家人群比较,我国农民血浆TC、TG、HDL-C和依此计算而得的LDL-C水平较低,而HDL-C/TC比值较高,CVD死亡率也较西方国家的为低。2.在TC、LDL-C与CVD死亡率之间无相关,但在红细胞油酸水平与CVD死亡率间有显著负相关。3.红细胞油酸水平与血浆TC含量间无相关,而与红细胞花生四烯酸水平呈显著负相关。指出油酸对CVD死亡率的影响有可能是通过另一条途径,即减低血小板的聚集作用。4.我国的CVD死亡率呈现明显的地区性分布,即南方低于北方。其分布与红细胞油酸含量,及大米摄取量的地区性分布呈明显的负关系。5.为解释CVD死亡率与红细胞油酸的负关系,本文提出了油酸可能置换了血小板膜磷脂中多不饱和脂肪酸的设想,但对大米保护CVD的作用则尚需有更多的调查和研究数据才能确证之。 | 范文洵 Parker R Parpia B 屈荫生 Cassano P Crawford M Leyton J 田巧珍 黎均耀 陈君石 Campbell C | 1992 | 营养学报1992，14，1： | 15 |
| 4 | Iron and non-alcoholic fatty liver disease显示文摘The mechanisms that promote liver injury in non-alcoholic fatty liver disease(NAFLD) are yet to be thoroughly elucidated. As such, effective treatment strategies are lacking and novel therapeutic targets are required. Iron has been widely implicated in the pathogenesis of NAFLD and represents a potential target for treatment. Relationships between serum ferritin concentration and NAFLD are noted in a majority of studies, although serum ferritin is an imprecise measure of iron loading. Numerous mechanisms for a pathogenic role of hepatic iron in NAFLD have been demonstrated in animal and cell culture models. However, the human data linking hepatic iron to liver injury in NAFLD is less clear, with seemingly conflicting evidence, supporting either an effect of iron in hepatocytes or within reticulo-endothelial cells. Adipose tissue has emerged as a key site at which iron may have a pathogenic role in NAFLD. Evidence for this comes indirectly from studies that have evaluated the role of adipose tissue iron with respect to insulin resistance. Adding further complexity, multiple strands of evidence support an effect of NAFLD itself on iron metabolism. In this review, we summarise the human and basic science data that has evaluated the role of iron in NAFLD pathogenesis. | Laurence J Britton V Nathan Subramaniam Darrell HG Crawford | 2016 | World Journal of Gastroenterology2016，22，36： | 14 |
| 5 | Redox therapeutics in hepatic ischemia reperfusion injury显示文摘Ischemia-reperfusion plays a major role in the injury experienced by the liver during transplantation. Much work has been done recently investigating the role of redox species in hepatic ischemia-reperfusion. As animal models are better characterized and developed, and more insights are gained into the pathophysiology of hepatic ischemia reperfusion injury in humans the questions into exactly how oxidants participate in this injury are becoming more refined. These questions include effects of cellular location, timing of injury, and ability of therapeutics to access this site are increasing our appreciation of the complexity of ischemia reperfusion and improving attempts to ameliorate its effects. In this review, we aim to discuss the various methods to alter redox chemistry during ischemia reperfusion injury and future prospects for preventing organ injury during hepatic ischemia reperfusion. | Rakesh P Patel John D Lang Alvin B Smith Jack H Crawford | 2014 | World Journal of Hepatology2014，6，1： | 9 |
| 6 | 阿片成瘾者中的人格障碍问题显示文摘本文采用多种人格障碍筛查表对接受戒毒治疗的80例阿片成瘾者进行了测查。结果显示,各种人格障碍(personalitydisorders,PDs)的现患率为86%,其中戏剧性PD、依赖性PD、回避性PD和边缘性PD各分别占44%、36%、35%和76%。具有统计学意义的多种PD为:(1)依赖性-回避性(OR值=13.9;95%可信限范围=4.55,42.83);(2)戏剧性-依赖性(OR值=2.8;95%可信限范围=1.11,7.26);(3)边缘性-戏剧性(OR值=5.5;95%可信限范围=1.45,20.87);(4)边缘性-依赖性(OR值=3.9;95%可信限范围=1.04,15.04)。此结果提示,在阿片成瘾者中存在着各种严重的人格障碍。 | Adenekan Oyefeso, Hamid Ghodse, Carmel Clancy, Vanessa Crawford, Stephen Byrne(Research Evaluation and Monitoring Unit Department of Psychiatry of Addictive Behaviour St George’s Hospital Medical School London SW17 ORE) | 1998 | 中国药物依赖性杂志1998，7，2： | 6 |
| 7 | Multi-length scale modeling of carburization,martensitic microstructure evolution and fatigue properties of steel gears显示文摘Multi-length scale modeling is performed to(i)predict the carburized case depth of SAE8620 steel gears by solving the Fick’s second law of diffusion,(ii)model the martensitic microstructure evolution in a grain inside the carburized case as well as to study the effect of stress cycling on retained austenite(RA)and martensite using a 3D phase-field model,(iii)simulate the effect of carburization and different RA contents on macroscale fatigue behavior of SAE8620 steel spur gear using the finite element method.The diffusion model predicts that the case depth increases with increasing heat treatment time and temperature.The phase-field simulations show that RA can transform to martensite during fatigue loading,where the extent of the transformation will depend on the type of stresses applied,i.e.stresses in a high stress regime or low stress regime of fatigue loading.Reverse transformation of martensite to austenite is also observed in low RA sample under high stress regime.The macroscale simulations show that the carburized case with high RA gives rise to better fatigue life compared to that with low RA. | Edward Charles Henry Crawford O’Brien Hemantha Kumar Yeddu | 2020 | Journal of Materials Science & Technology2020，47，14： | 5 |
| 8 | New spinal robotic technologies显示文摘Robotic systems in surgery have developed rapidly. Installations of the da Vinci Surgical System® (Intuitive Surgical, Sunnyvale, CA,, USA), widely used in urological and gynecological procedures, have nearly doubled in the United States from 2010 to 2017. Robotics systems in spine surgery have been adopted more slowly;however, users are enthusiastic about their applications in this subspecialty. Spinal surgery often requires fine manipulation of vital structures that must be accessed via limited surgical corridors and can require repetitive tasks over lengthy periods of time — issues for which robotic assistance is well-positioned to complement human ability. To date, the United States Food and Drug Administration (FDA) has approved 7 robotic systems across 4 companies for use in spinal surgery. The available clinical data evaluating their efficacy have generally demonstrated these systems to be accurate and safe. A critical next step in the broader adoption of surgical robotics in spine surgery is the design and implementation of rigorous comparative studies to interrogate the utility of robotic assistance. Here we discuss current applications of robotics in spine surgery, review robotic systems FDA-approved for use in spine surgery, summarize randomized controlled trials involving robotics in spine surgery, and comment on prospects of robotic-assisted spine surgery. | Bowen Jiang Tej DAzad Ethan Cottrill Corinna CZygourakis Alex MZhu Neil Crawford Nicholas Theodore | 2019 | Frontiers of Medicine2019，13，6： | 5 |
| 9 | 密苏里州立公园ADA指导委员会对公众参与有效性的评价显示文摘本文对美国州立公园设计过程中公众参与的有效性进行了探讨。通过国家公园密苏里分部的有关实例研究,讨论了依据《美国伤残人法》(ADA),市民指导委员会在州立公园体系建设中的作用,以及对公众参与有效性产生影响的因素。 | Pat Crawford 刘健 | 2002 | 国外城市规划2002，17，2： | 5 |
| 10 | Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS)显示文摘 | Nuh N. Rahbari O. James Garden Robert Padbury Mark Brooke-Smith Michael Crawford Rene Adam Moritz Koch Masatoshi Makuuchi Ronald P. Dematteo Christopher Christophi Simon Banting Val Usatoff Masato Nagino Guy Maddern Thomas J. Hugh Jean-Nicolas Vauthey Pau | 2011 | Surgery2011，，5： | 4 |
| 11 | Development of Shallow Footing Anti-Ram Bollard System Through Modeling and Testing显示文摘In past terrorist attacks, vehicle borne improvised explosive devices (VBIED) have been the primary manner of attacking buildings and infrastructures. Preventing unauthorized vehicles from approaching a protected area with anti-ram systems would maintain an established standoff distance against moving and stationary vehicles and consequently reduce blast and debris threats. This strategy has been considered the first line of defence against terrorists. Several types of anti-ram devices have been developed in accordance with U. S. Department of State K-rating criteria, for example, wedge barriers, rising beams, sliding/swing gates, and drop arms. However, these devices typically need a deep foundation for installation and can't be implemented into many locations where a depth of excavation is limited in order to protect utility lines of buildings and infrastructures. This paper presents a recent development of a series of shallow footing anti-ram bollard systems (SFABS) that can satisfy K-12 rating with only five-inch thick footing. A high-fidelity physics based finite element technique with a vehicle crash model is used for predicting anti-ram capacity and determining design parameters of the SFABS. Full-scale vehicle crash tests of the developed SFABS systems have been carried out to validate the design and analysis. | CRAWFORD John E | 2006 | Transactions of Tianjin University2006，12，B09： | 4 |
| 12 | Baculovirus-derived hemagglutinin vaccines protect against lethal influenza infections by avian H5 and H7 subtypes显示文摘 | Crawford J Wilkinson B Vosnesensky A | 1999 | Vaccine1999，17，18： | 3 |
| 13 | 使用离子束治疗法成功治疗侵入眼内的结膜鳞状上皮细胞癌显示文摘由于长时间的紫外线照射,结膜鳞状上皮细胞癌在世界范围内变得越来越流行。尽管如此,原发结膜鳞状上皮细胞癌侵人眼内仍然十分罕见,因此经常导致误诊。侵及眼部大且侵袭力强的病变仅通过标准的切除手术和冷冻术往往较难治愈。对于这种病变的治疗,大多数研究者会建议行眼球摘除术,当有证据显示病变侵及眼眶时则行眶内容物剜除术^1-4。目前的病例显示使用离子束治疗侵入眼内的结膜鳞状上皮细胞癌是眼球摘除术外的另一种选择。就我们所知,这是第一例关于使用离子束治疗侵袭性结膜鳞状上皮细胞癌的病例报道。 | Krista M. Ramonas R. Max Conway Inder K. Daftari J. Brooks Crawford Joan M. O' Brien 张弛(译) | 2006 | 美国医学会眼科杂志(中文版)2006，18，3： | 3 |
| 14 | Ponseti method compared with soft-tissue release for the management of clubfoot:A meta-analysis study显示文摘AIM: To compare the functional outcomes of patients who underwent open surgery vs Ponseti method for the management of idiopathic clubfoot and to determine whether correlations exist between functional outcome and radiographic measurements.METHODS: A meta-analysis of the literature was conducted for studies concerning primary treatment of patients with idiopathic clubfoot. We searched PubM ed Medline, EMBASE, and the Cochrane Library databases from January 1950 to October 2011. Meta-analyses were performed on outcomes from 12 studies. Pooled means, SDs, and sample sizes were either identified in the results or calculated based on the results of each study.RESULTS: Overall, 835 treated idiopathic clubfeet in 516 patients were reviewed. The average follow-up was 15.7 years. Patients managed with Ponseti method did have a higher rate of excellent or good outcome than patients treated with open surgery(0.76 and 0.62, respectively), but not quite to the point of statistical significance(Q = 3.73, P = 0.053). Age at surgery wasnot correlated with the functional outcome for the surgically treated patients(r =-0.32, P = 0.68). A larger anteroposterior talocalcaneal angle was correlated with a higher rate of excellent or good outcomes(r = 0.80, P = 0.006). There were no other significant correlations between the functional and radiographic outcomes.CONCLUSION: The Ponseti method should be considered the initial treatment of idiopathic clubfeet, and open surgery should be reserved for clubfeet that cannot be completely corrected. | Marios G Lykissas Alvin H Crawford Emily A Eismann Junichi Tamai | 2013 | World Journal of Orthopedics2013，4，3： | 3 |
| 15 | Histologic Findings in Alcoholic Liver Disease显示文摘 | James M. Crawford | 2012 | Clinics in Liver Disease2012，，4： | 3 |
| 16 | 进化论心理学:自然选择与人之本性显示文摘进化论心理学综合了达尔文的自然选择进化理论和当代心理学的研究方法,试图解释人类认知和情感适应功能的起源,并解释这些功能机制在现代人类社会中的作用。文章主要着眼于回答自然选择是如何创造条件,使有机生命体从环境挑战中生存下来的问题;澄清关于进化论的一些错误概念;以及探讨进化论如何能够帮助我们更好地理解人类行为。文章最后简要地阐述了科学界和政治界对现存一些进化论观念的思辨。 | Charles Crawford 张彦彦 | 2011 | 科学技术哲学研究2011，28，1： | 3 |
| 17 | Molecular and physiological aspects of nitrate uptake in plants显示文摘 | Nigel M Crawford Anthony D.M Glass | 1998 | Trends in Plant Science1998，，10： | 3 |
| 18 | Experience with 1509 patients undergoing thoracoabdominal aortic operations显示文摘 | Svensson LG Crawford ES Hess KR Coselli JS Safi HJ | 1993 | J Vasc Surg1993，17，2： | 2 |
| 19 | Posthepatectomy liver failure: A definition and grading by the International Study Group of Liver Surgery (ISGLS)显示文摘 | Nuh N. Rahbari O. James Garden Robert Padbury Mark Brooke-Smith Michael Crawford Rene Adam Moritz Koch Masatoshi Makuuchi Ronald P. Dematteo Christopher Christophi Simon Banting Val Usatoff Masato Nagino Guy Maddern Thomas J. Hugh Jean-Nicolas Vauthey Pau | 2011 | Surgery2011，，5： | 2 |
| 20 | The impact of phlebotomy in nonalcoholic fatty liver disease: A prospective, randomized, controlled trial显示文摘 | Leon A. Adams Darrell H. Crawford Katherine Stuart Michael J. House Timothy G. St. Pierre Malcolm Webb Helena L.I. Ching Jenny Kava Michael Bynevelt Gerry C. MacQuillan George Garas Oyekoya T. Ayonrinde Trevor A. Mori Kevin D. Croft Xianwa Niu Gary P. Jef | 2015 | Hepatology2015，，5： | 2 |
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