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| 1 | Effect of propranolol on the splanchnic and peripheral renin angiotensin system in cirrhotic patients显示文摘AIM:To evaluate the effect of β-blockade on angiotensins in the splanchnic and peripheral circulation of cirrhotic patients and also to compare hemodynamic parameters during liver transplantation according to propranolol pre-treatment or not. METHODS:Patients were allocated into two groups:outpatients with advanced liver disease(LD) and during liver transplantation(LT). Both groups were subdivided according to treatment with propranolol or not. Plasma was collected through peripheral venipuncture to determine plasma renin activity(PRA),Angiotensin(Ang) Ⅰ,Ang Ⅱ,and Ang-(1-7) levels by radioimmunoassay in LD group. During liver transplantation,hemodynamic parameters were determined and blood samples were obtained from the portal vein to measure renin angiotensin system(RAS) components.RESULTS:PRA,Ang Ⅰ,Ang Ⅱ and Ang-(1-7) were signifi cantly lower in the portal vein and periphery in all subgroups treated with propranolol as compared to non-treated. The relationships between Ang-(1-7) and Ang Ⅰ levels and between Ang Ⅱ and Ang Ⅰ were significantly increased in LD group receiving propranolol. The ratio between Ang-(1-7) and Ang Ⅱ remained unchanged in splanchnic and peripheral circulation in patients under β-blockade,whereas the relationship between Ang Ⅱ and Ang Ⅰ was significantly increased in splanchnic circulation of LT patients treated with propranolol. During liver transplantation,cardiac output and index as well systemic vascular resistance and index were reduced in propranolol-treated subgroup. CONCLUSION:In LD group,propranolol treatment reduced RAS mediators,but did not change the ratio between Ang-(1-7) and Ang Ⅱ in splanchnic and peripheral circulation. Furthermore,the modification of hemodynamic parameters in propranolol treated patients was not associated with changes in the angiotensin ratio. | Walkíria Wingester Vilas-Boas Antnio Ribeiro-Oliveira Jr Renata da Cunha Ribeiro Renata Lúcia Pereira Vieira Jerusa Almeida Ana Paula Nadu Ana Cristina Sim■es e Silva Robson Augusto Souza Santos | 2008 | World Journal of Gastroenterology2008，14，44： | 2 |
| 2 | 查看详情显示文摘 | Wang X F da Cunha Lima I C Lei X L | | 0，，： | 1 |
| 3 | The nonsub-sampled contourlet transform:theory,design and applica-tions显示文摘 | Da Cunha A L Zhou Jiangping Do M N | 2006 | IEEE Trans on Image Proecess2006，15，10： | 1 |
| 4 | The nonsubsampled contourlet transform:Theory,design and applications显示文摘 | CUNHA A L da ZHOU J DO M N | 2006 | IEEE Trans Image Process2006，15，10： | 1 |
| 5 | The Nonsubsampled Contourlet Transform:Theory,Design,and Applications显示文摘 | Arthur L da Cunha Jianping Zhou Minh N Do | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 6 | The nonsubsampled Contour-let transform:theory,design,and applications 显示文摘 | Da Cunha A L Zhou Jianpin Do M N | 2006 | IEEE TransactionsImage on Processing2006，15，10： | 1 |
| 7 | The nonsubsampled contourlet transform: theory, design, and applications 显示文摘 | Da Cunha A L Zhou J P Do M N | 2006 | IEEE Transactions on Image Processing(S1057-7149)2006，15，10： | 1 |
| 8 | The Nonsubsampled Contourlet Transform: Theory, Design, and Applications 显示文摘 | da Cunha A L Zhou Jianping Do M N | 2006 | IEEE Transactions on Image Processing(S1057-7149)2006，15，10： | 1 |
| 9 | Two Pseudomonas Syringae Type III Effectors Inhibit RIN4-Regulated Basal Defense in Arabidopsis 显示文摘 | KIM M G DA CUNHA L MCFALL A J | 2005 | Cell2005，121，5： | 1 |
| 10 | The nonsubsampled contourlet transform: theory, design, and applications显示文摘 | da Cunha A L Zhou J P Do M N | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 11 | The nonsubsampled contourlet transform:Theory,design,and application显示文摘 | Da Cunha A L Zhou J Do M N | | 0，，10： | 1 |
| 12 | Characterization of the clonal profile of MRSA isolated in neonatal and pediatric intensive care units of a University Hospital显示文摘 | Pereira VC Riboli DF da Cunha Mde L | 2014 | Ann Clin Microbiol Antimicrob2014，，13： | 1 |
| 13 | Palmitate in- duces a pro-inflammatory response in human pancreatic is- lets that mimics CCL2 expression by beta cells in type 2 dia- betes 显示文摘 | Igoillo-Esteve M Marselli L Cunha DA | 2010 | Diabetologia2010，53，7： | 1 |
| 14 | The nonsubsampled contourlet transform:theory,design,and applications显示文摘 | Da Cunha A L Zhou Jianping Do M N | | 0，，10： | 1 |
| 15 | Antimicrobial peptides and immunolocalization of a LTP in vigna unguiculata seeds 显示文摘 | CARVALHO A O MACHADO O L T da CUNHA M | 2001 | Plant Physiogy and Biochemistry2001，39，： | 1 |
| 16 | The nonsubsampled contourlet transform: theory, design, and applications 显示文摘 | Da Cunha A L Zhou J Do M N | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 17 | The Norisubsanipled Contourlet transform : TTieory,Dosign and Application 显示文摘 | Cunha A L da Zhou J P and Do M IN | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 18 | The Nonsubsampled Contourlet Transform:Theory, Design and Applications 显示文摘 | da Cunha A L Zhou J P Do M N | 2006 | IEEE Transactions on Image Proceasing2006，15，10： | 1 |
| 19 | The nonsubsampled contourlet transform theory,design,and application显示文摘 | DA CUNHA A L ZHOU J DO M N | 2006 | IEEE Transactions on Image Processing2006，15，10： | 1 |
| 20 | The Nonsubsampled Contourlet Transform: Theory, Design, and Applications显示文摘 | da Cunha A L Zhou J Do M N | 2006 | IEEE Trans on Image Processing2006，15，10： | 1 |
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