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| 1 | G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis显示文摘Estrogens play important roles in the development and progression of multiple tumor types.Accumulating evidence points to the significance of estrogen action not only in tumors of hormonally regulated tissues such as the breast,endometrium and ovary,but also in the development of colorectal cancer(CRC).The effects of estrogens in physiological and pathophysiological conditions are mediated by the nuclear estrogen receptorsαandβ,as well as the membranebound G protein-coupled estrogen receptor(GPER).The roles of GPER in CRC development and progression,however,remain poorly understood.Studies on the functions of GPER in the colon have shown that this estrogen receptor regulates colonic motility as well as immune responses in CRC-associated diseases,such as Crohn’s disease and ulcerative colitis.GPER is also involved in cell cycle regulation,endoplasmic reticulum stress,proliferation,apoptosis,vascularization,cell migration,and the regulation of fatty acid and estrogen metabolism in CRC cells.Thus,multiple lines of evidence suggest that GPER may play an important role in colorectal carcinogenesis.In this review,we present the current state of knowledge regarding the contribution of GPER to colon function and CRC. | Damian Jacenik Ellen J Beswick Wanda M Krajewska Eric R Prossnitz | 2019 | World Journal of Gastroenterology2019，25，30： | 6 |
| 2 | Vertically Unstable Pelvic Fractures Fixed with Percutaneous Iliosacral Screws: Does Posterior Injury Pattern Predict Fixation Failure?显示文摘 | Damian R Griffin Adam J Starr Charles M Reinert Alan L Jones Shelly Whitlock | 2006 | Journal of Orthopaedic Trauma ( Suppl)2006，，1： | 1 |
| 3 | Intravaginal gels as drug delivery system显示文摘 | Justintemu M Damian F Kinget R | 2004 | Journal of Women'' s Health2004，13，7： | 1 |
| 4 | Intravaginal gels as drug delivery system 显示文摘 | JUSTIN-TEMU M DAMIAN F KINGET R | 2004 | J WoMens Health (Larchmt)2004，13，7： | 1 |
| 5 | On the mechanisms of beryl flotation in the presence of some metallic cations显示文摘 | Torem M L Peres A E Damian R A | 1992 | Minerals Engineering1992，5，1012： | 1 |
| 6 | Auto radiators-study regarding air flow along the channels 显示文摘 | DAMIAN R M PLESA A GIURGIU O | 2016 | Energy Procedia2016，85，： | 1 |
| 7 | Vertically unstable pelvic fractures fixed with percutaneous iliosacral screws: does posterior injury pattern predict fixation failure 显示文摘 | Griffin Damian R Start Adam J Reinert Charles M | 2006 | J Orthop Trauma2006，1，： | 1 |
| 8 | Intravaginal gels as drug delivery systems 显示文摘 | JUSTIN-TEMU M DAMIAN F KINGET R | 2004 | J Womens Health ( Larchmt )2004，13，7： | 1 |
| 9 | lntrawlginal gels as drug delivery ststems显示文摘 | Justin Temu M Damian F Kinget R | 2004 | J Womens Health(Larchmt)2004，13，7： | 1 |
| 10 | Semantic and Phonological Codes Interact in Single Word Production显示文摘 | Damian M F Martin R C | 1999 | Journal of Experimental Psychology:Learning Memory and Cognition1999，25，： | 1 |
| 11 | Intravaginal gels as drug delivery system 显示文摘 | JUSTIN-TEMU M DAMIAN F KINGET R | 2004 | J Womens health (Larchmt)2004，13，7： | 1 |
| 12 | Intravaginal gels as drug delivery systems 显示文摘 | Justin-Temu M Damian F Kinget R | 2004 | J Womens Health2004，13，7： | 1 |
| 13 | Intravaginal gels as drug delivery systems显示文摘 | Justin-Temu M Damian F Kinget R | 2004 | J Womens Health(Larchmt)2004，13，7： | 1 |
| 14 | Intravaginal gels as drug delivery systems显示文摘 | Justin-Temu M Damian F Kinget R | 2004 | J Womens Health (Larchmt)2004，13，7： | 1 |
| 15 | Uropathogenic Escherichia coli-ExPEC pathotype, the best characterized 显示文摘 | Usein C R Damian M | 2003 | Bacteriol Virusol Parazitol Epidemiol2003，48，1： | 1 |
| 16 | Intravaginal gels as drug delivery systems显示文摘 | Justin-Temu M Damian F Kinget R | 2004 | J Women''s Health2004，13，7： | 1 |
| 17 | Intravaginal gels as drug delivery systems 显示文摘 | JUSTIN-TEMU M DAMIAN F KINGET R | 2004 | Womens Health (Larchmt)2004，13，7： | 1 |
| 18 | Semantic priming in the name retrieval of objects and famous faces显示文摘 | Damian M F Rahman R A | 2003 | British Journal of Psychology2003，94，： | 1 |
| 19 | Intravaginal gels as drug delivery systems显示文摘 | Justin-Temu M Damian F Kinget R | 2004 | J Womens Health (Larchmt)2004，13，7： | 1 |
| 20 | In vitro antioomycete activity of Artemisia ludoviciana extracts against Phytophthora spp显示文摘 | Damian Badillo L M Martinez Mu oz R E Salgado Garciglia R | 2010 | Boletin Latinoamericano y del Caribe de Plantas Medicinalesy Aromaticas2010，9，2： | 1 |
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