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| 1 | 老年男性勃起功能及迟发性性腺功能减退症状与下尿路症状严重性的关系显示文摘本文旨在研究土耳其爱琴海地区的老年男性下尿路症状(LUTSs)、勃起功能障碍(ED)和有症状的迟发性性腺功能减退症(SLOH)三者间的关系。符合以下标准的500名男性患者被纳入该研究:40周岁以上;过去6个月内有稳定的性关系;在六个泌尿外科诊所之一进行过就诊登记。每位患者均行血清PSA、睾酮水平及尿流率的检测,并填写国际前列腺症状评分和生活质量评分(IPSS-QoL)量表、国际勃起功能指数(IIEF)问卷和老年男性症状(AMS)量表。在所有的研究对象中,23.9%的患者有轻度LUTSs,53.3%有中度LUTSS,22.8%有重度LUTSS。每组间总睾酮水平无明显差异。除此之外,69.6%的病人患有ED,且ED的发生率与LUTS严重性呈正相关。71.2%的患者出现SLOH(AMS〉27),且IPSS评分越高,严重的性腺功能减退症状的发生率也越高。相关性分析显示以上三种问卷分数之间有显著关联。总之,LUTS严重性是ED和SLOH的非年龄依赖性危险因素,LUTS严重性和SLOH症状之间似乎有显著的相关性,但还需要从病因学和生物学角度进行深入阐明。 | Ozan Bozkurt Deniz Bolat Omer Demir Oktay Ucer Ali Sahin Burak Ozcift Abdulkadir Pekta Tahir Turan Bilal H Gümü Ertan Cans Ahmet Bolukbasi Haluk Erol Adil Esenx | 2013 | Asian Journal of Andrology2013，15，6： | 4 |
| 2 | Predictors of poor outcome in gastrointestinal bleeding in emergency department显示文摘AIM: To determine the prognostic risk factors of gastrointestinal bleeding in emergency department cases.METHODS: The trial was a retrospective single-center study involving 600 patients over 18-years-old and carried out with approval by the Institutional Ethics Committee. Patient data included demographic characteristics, symptoms at admission, past medical history, vital signs, laboratory results, endoscopy and colonoscopy results, length of hospital stay, need of intensive care unit(ICU) admission, and mortality. Mortality rate was the principal endpoint of the study, while duration of hospital stay, required interventional treatment, and admission to the ICU were secondary endpoints.RESULTS: The mean age of patients was 61.92-yearsold. Among the 600 total patients, 363(60.5%) underwent upper gastrointestinal endoscopy and the most frequent diagnoses were duodenal ulcer(19.2%) and gastric ulcer(12.8%). One-hundred-and-fifteen(19.2%) patients required endoscopic treatment, 20(3.3%) required surgical treatment, and 5(0.8%) required angiographic embolization. The mean length of hospital stay was 5.21 ± 5.85 d. The mortality rate was 6.3%. The ICU admission rate was 5.3%. Patients with syncope, higher blood glucose levels, and coronary artery disease had significantly higher ICU admission rates(P = 0.029, P = 0.043, and P = 0.002, respectively). Patients with low thrombocyte levels, high creatinine, high international normalized ratio, and high serum transaminase levels had significantly longer hospital stay(P = 0.02, P = 0.001, P = 0.019, and P = 0.005, respectively). Patients who died had significantly higher serum blood urea nitrogen and creatinine levels(P = 0.016 and P = 0.038), and significantly lower mean blood pressure and oxygen saturation(P = 0.004 and P = 0.049). Malignancy and low Glasgow coma scale(GCS) were independent predictive factors of mortality.CONCLUSION: Prognostic factors for gastrointestinal bleeding in emergency room cases are malignancy, hypotension on admission, low GCS, and impaired kidney function. | Ender Kaya Mehmet Ali Karaca Deniz Aldemir M Mahir Ozmen | 2016 | World Journal of Gastroenterology2016，22，16： | 4 |
| 3 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | Effect of low-protein diet supplemented with Keto acids on progression of disease in patients with chronic renal failure显示文摘 | Deniz Am Agli M Ensari C | 2000 | Nephron2000，84，3： | 1 |
| 5 | Effects of inlet flow field conditions on the performance of centrifugal compressor diffusers:straight channel diffuser显示文摘 | Deniz S Greitzer E M Cumpsty N A | 2000 | ASME Journal of Turbomachinery2000，122，1： | 1 |
| 6 | The Extent and Nature of Opportunity Identification by Experienced Entrepreneurs显示文摘 | Deniz U Westhead P Wright M | | 0，，02： | 1 |
| 7 | Effect of respiratory muscle endurance training in patients with COPD undergoing pulmonary rehabilitation显示文摘 | Mador M Deniz O Aggarwal A | 2005 | Chest2005，128，： | 1 |
| 8 | Components of Innovation Ecosystems:A Cross-Country Study显示文摘 | BIROL M DENIZ G | 2011 | International Research Journal of Finance and Economics2011，，76： | 1 |
| 9 | ENCARA2:Realtime detection of multiple faces at different resolutions in video stream显示文摘 | CASTRILLON M DENIZ O GUERRA C | 2007 | Journal of Visual Communication and Image Representation2007，18，2： | 1 |
| 10 | Mild hypothermia improves survival during hemorrhagic shock without affecting bacterial translocation显示文摘 | Deniz T Agalar C Ozdogan M | 2009 | J Invest Surg2009，22，1： | 1 |
| 11 | Human NKI and NK2 subsets determined by purification of IFN - γ - secreting and IFN - γ - nonsecreting NK cells 显示文摘 | Deniz G Akdis M Aktas E | 2002 | Eur J Immunol2002，32，： | 1 |
| 12 | Recovery of Zinc and Lead From Zinc Plant Residue显示文摘 | Turan M Deniz Ahundogan H Soner Tumen Fikret | 2004 | Hydrometallurgy2004，75，4： | 1 |
| 13 | Substituent effects on the photochromic of bichromophoric oxazines显示文摘 | Deniz E Tomasulo M Sortino S | | 0，，19： | 1 |
| 14 | Single-pair fluorescence resonance energy transfer on freely diffusing molecules: observation of forster distance dependence and subpo-pulations 显示文摘 | DENIZ A A DAHAN M GRUNWELL J R | 1999 | Proc Natl Acad Sci1999，96，： | 1 |
| 15 | Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis显示文摘 | Stefan Leucht Andrea Cipriani Loukia Spineli Dimitris Mavridis Deniz ?rey Franziska Richter Myrto Samara Corrado Barbui Rolf R Engel John R Geddes Werner Kissling Marko Paul Stapf Bettina L?ssig Georgia Salanti John M Davis | 2013 | The Lancet2013，，： | 1 |
| 16 | The effect of head rotation on intraocular pressure in prone position:a randomized trial显示文摘 | Nuri Deniz M Erakgün A Sertz N | 2013 | Rev Bras Anesthesiol2013，63，2： | 1 |
| 17 | Compressive hyperextension injury of C2-C3 managed with anterior plate fixation: case report 显示文摘 | Deniz FE Caeli S Zileli M | 2007 | Turk Neurosurg2007，17，2： | 1 |
| 18 | The impact of different nasal packings on postoperative complications显示文摘 | DENIZ M CIFTCI Z ISIK A | 2014 | Am J Otolaryngol2014，35，： | 1 |
| 19 | In vivo comparison of laser fluorescence measurements with conventional methods for occlusal caries detection 显示文摘 | TORAMAN ALKURT M PEKER I DENIZ ARISU H | 2007 | Lasers Med Sci2007，21，： | 1 |
| 20 | An investigation ofconflict resolution strategies of adolescents显示文摘 | Ayas T Deniz M Kagan M | 2010 | Proce-dia-Social and Behavioral Sciences2010，2，2： | 1 |
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