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| 1 | Improvedendoscopicretrogradecholangiopancreatographybrushincreases diagnosticyieldofmalignantbiliarystrictures显示文摘AIM: To determine if a new brush design could im-prove the diagnostic yield of biliary stricture brushings. METHODS: Retrospective chart review was performed of all endoscopic retrograde cholangiopancreatography procedures with malignant biliary stricture brushing between January 2008 and October 2012. A standard wire-guided cytology brush was used prior to proto-col implementation in July 2011, after which, a new 9 French wire-guided cytology brush(Infinity sampling device, US Endoscopy, Mentor, OH) was used for all cases. All specimens were reviewed by blinded pa-thologists who determined whether the sample waspositive or negative for malignancy. Cellular yield was quantified by describing the number of cell clusters seen. RESULTS: Thirty-two new brush cases were compared to 46 historical controls. Twenty-five of 32 (78%) cases in the new brush group showed abnormal cellular find-ings consistent with malignancy as compared to 17 of 46(37%) in the historical control group(P = 0.0003). There was also a significant increase in the average number of cell clusters of all sizes(21.1 vs 9.9 clusters, P = 0.0007) in the new brush group compared to his-torical controls. CONCLUSION: The use of a new brush design for brush cytology of biliary strictures shows increased di-agnostic accuracy, likely due to improved cellular yield, as evidenced by an increase in number of cellular clus-ters obtained. | Shieh FK Luong-Player A Khara HS Liu H Lin F Shellenberger MJ Johal AS Diehl DL | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 4 |
| 2 | Detection and quantifica-tion of mutations in the plasma of patients with colorectal tumors显示文摘 | DIEHL F LI M DRESSMAN D | 2005 | Proc Natl Acad Sci USA2005，102，45： | 1 |
| 3 | Cytochrome P450 family member CYP704B2 catalyzes the omega } - hydrnxylation of fatty acids and is required for anther cutin biosynthesis and pollen exine formation in rice 显示文摘 | Li H Pinot F Sauveplane V Werck-Reichhart D Diehl P Schreiber L Franke R Zhang P Chert L Gao Y Liang W ZhangD | 2010 | Plant Cell2010，22，1： | 1 |
| 4 | Systematic study of microwave absorption, heating, and microstructure evolution of porous copper powder metal compacts显示文摘 | Ma J Diehl J F Johnson E J | 2007 | Journal of Applied Physics2007，101，07： | 1 |
| 5 | Development of personalized tumor biomarkers using massively parallel sequencing显示文摘 | Leafy RJ Kinde I Diehl F | 2010 | Sci Transl Med2010，2，20： | 1 |
| 6 | Inhibition of eyelin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitinproteasome pathway 显示文摘 | Diehl JA Zindy F Sherr CJ | 1997 | Genes Dev1997，11，8： | 1 |
| 7 | Circulating mutant DNA to assess tumor dynamics显示文摘 | Diehl F Schnidt K Choti M A | 2009 | Nat Med2009，14，9： | 1 |
| 8 | Detection and quantification of mutations in the plasma of patients with colorectal tumors 显示文摘 | Diehl F | 2005 | Prec Natl Acad Sci2005，102，16： | 1 |
| 9 | Circulating mutant DNA to assess tumor dynam-ics显示文摘 | DIEHL F SCHMIDT K CHOTI MA ROMANS K GOODMANS LI M | 2008 | Nature medicine2008，14，9： | 1 |
| 10 | Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization显示文摘 | Diehl J A Cheng M Roussel M F | 1998 | Genes Dev1998，12，： | 1 |
| 11 | Circulating mutantDNA to assess tumor dynamics显示文摘 | DIEHL F SCHMIDT K CHOTI M A | 2008 | Nat Med2008，14，9： | 1 |
| 12 | On the hydro- desulfurization of FCC gasoline: a review 显示文摘 | Brunet S Mey D Pérot G Bouchy C Diehl F | 2005 | Applied Catalysis A: General2005，278，2： | 1 |
| 13 | Detection and quantifica- tion of mutations in the plasma of patients with colorectal tumors显示文摘 | Diehl F Li M Dressman D | 2005 | Pro Nail Acad Sci USA2005，102，16： | 1 |
| 14 | Cell surface expression of bacterial esterase A by Saccharomyces cerevisiae and its enhancement by constitutive activation of the cellular unfolded protein response 显示文摘 | Breinig F Diehl B Rau S | 2006 | Appl Environ Microbiol2006，72，11： | 1 |
| 15 | Circulating mutant DNA to as- sess tumor dynamics显示文摘 | Diehl F Schmidt K Choti MA | 2008 | Nat Med2008，14，9： | 1 |
| 16 | Development of personalized tumor biomarkers using massively parallel sequencing 显示文摘 | Leary RJ Kinde I Diehl F | 2010 | Sci Transl Med2010，2，20： | 1 |
| 17 | Food irradiation-past, present and future 显示文摘 | Diehl J F | 2002 | Ra- diat Phys Chem2002，63，3： | 1 |
| 18 | Non-alcoholic fatty liver disease:lumen -liver interactions and possible role for probiotics显示文摘 | SOLGA S F DIEHL A M | 2003 | J Hepatol2003，38，5： | 1 |
| 19 | Adenomatous polyposiscoli ( APC) regulates multiple signaling pathways by enhancingglycogen synthase kinase-3 ( GSK-3) activity显示文摘 | Valvezan A J Zhang F Diehl J A | 2012 | J Biol Chem2012，287，6： | 1 |
| 20 | Detection and quantification of mutations in the plasma of patients with colorectal tumors 显示文摘 | Diehl F Meng L Dressman D | 2005 | Proc Natl Acad Sci U S A2005，102，16： | 1 |
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