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| 1 | International consensus statement on robotic hepatectomy surgery in 2018显示文摘The robotic surgical system has been applied in liver surgery. However,controversies concerns exist regarding a variety of factors including the safety,feasibility, efficacy, and cost-effectiveness of robotic surgery. To promote the development of robotic hepatectomy, this study aimed to evaluate the current status of robotic hepatectomy and provide sixty experts' consensus and recommendations to promote its development. Based on the World Health Organization Handbook for Guideline Development, a Consensus Steering Group and a Consensus Development Group were established to determine the topics, prepare evidence-based documents, and generate recommendations. The GRADE Grid method and Delphi vote were used to formulate the recommendations. A total of 22 topics were prepared analyzed and widely discussed during the 4 meetings. Based on the published articles and expert panel opinion, 7 recommendations were generated by the GRADE method using an evidence-based method, which focused on the safety, feasibility, indication,techniques and cost-effectiveness of hepatectomy. Given that the current evidences were low to very low as evaluated by the GRADE method, further randomized-controlled trials are needed in the future to validate these recommendations. | Rong Liu Go Wakabayashi Hong-Jin Kim Gi-Hong Choi Anusak Yiengpruksawan Yuman Fong Jin He Ugo Boggi Roberto I Troisi Mikhail Efanov Daniel Azoulay Fabrizio Panaro Patrick Pessaux Xiao-Ying Wang Ji-Ye Zhu Shao-Geng Zhang Chuan-Dong Sun Zheng Wu Kai-Shan Tao Ke-Hu Yang Jia Fan Xiao-Ping Chen | 2019 | World Journal of Gastroenterology2019，25，12： | 23 |
| 2 | Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection显示文摘AIM:To test the psychometric properties of a Chinese [(Hong Kong) HK] translation of the chronic liver disease questionnaire (CLDQ).METHODS:A Chinese (HK) translation of the CLDQ was developed by iterative translation and cognitive debriefing.It was then administered to 72 uncomplicated and 78 complicated chronic hepatitis B (CHB) patients in Hong Kong together with a structured questionnaire on service utilization,and the Chinese (HK) SF-36 Health Survey Version 2 (SF-36v2).RESULTS:Scaling success was ≥ 80% for all but three items.A new factor assessing sleep was found and items of two (Fatigue and Systemic Symptoms) subscales tended to load on the same factor.Internal consistency and test-retest reliabilities ranged from 0.58-0.90 for different subscales.Construct validity was confirmed by the expected correlations between the SF-36v2 Health Survey and CLDQ scores.Mean scores of CLDQ were significantly lower in complicated compared with uncomplicated CHB,supporting sensitivity in detecting differences between groups.CONCLUSION:The Chinese (HK) CLDQ is valid,reliable and sensitive for patients with CHB.Some modif ications to the scaling structure might further improve its psychometric properties. | Elegance Ting Pui Lam Cindy Lo Kuen Lam Ching Lung Lai Man Fung Yuen Daniel Yee Tak Fong | 2009 | World Journal of Gastroenterology2009，15，26： | 16 |
| 3 | Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B显示文摘 | Man-Fung Yuen Yasuhito Tanaka Daniel Yee-Tak Fong James Fung Danny Ka-Ho Wong John Chi-Hang Yuen David Yiu-Kuen But Annie On-On Chan Benjamin Chun-Yu Wong Masashi Mizokami Ching-Lung Lai | 2008 | Journal of Hepatology2008，，1： | 5 |
| 4 | 肺癌全基因组测序显示文摘肺癌是全球肿瘤发病率和病死率的主因,且预后很差。加强对肿瘤生物学的认识对肺癌研究至关重要。被誉为'下一代测序技术'的NGS技术(next-generation sequencing)是一种针对全基因组鉴定的有力工具,可以对致癌体细胞突变进行全面检测。大多数的NGS技术是基于平台特异性DNA文库进行多重聚合酶链反应(polymerase chain reaction,PCR),从而对目的基因扩增后测序。这种技术适用于高通量测序,可以检测出肿瘤中出现的全部基因组变异。缺点是这种技术需要在时间、实验设备、计算机数据分析、生物信息技术等各方面的大量投入。NGS技术已广泛应用于全基因组、外显子组、转录组和表观基因组的研究中,为肺癌研究和医疗模式带来改变。这项新技术的开展将转变当前对致癌信号通路的认识,可为癌症诊疗提供新的分子靶点。肺癌体细胞突变已有NGS技术的分析报道,但大规模基因组研究仍在进行中。个体化治疗策略将改善那些潜在获益患者的治疗方式,避免'无辜'患者受无效治疗带来的高额费用和不良反应。NGS的组织化、计算机化和生物信息化技术推动了科技的进步,同时,患者知情权和数据发布的相关伦理问题也浮现出来。信号通路中,驱动基因(driver gene)突变和传递基因(passenger gene)突变的区别,需要对测序结果进行细致解读。解读准确与否取决于DNA提取的样本类型、样本处理技术和样本含量。肿瘤异质性也会降低肿瘤基因突变的检测效能。NGS技术将推动对肿瘤基因突变的基础和临床研究,而且,也可应用于单细胞和游离的循环DNA,未来还将用于从体液和肿瘤亚群中获取的DNA样本。如果能进一步降低费用、提高检验速度和精度,NGS技术无疑将会成为肺癌研究的绝佳选择。 | Marissa Daniels Felicia Goh Casey M. Wright Krishna B. Sriram Vandana Relan Belinda E. Clarke Edwina E. Duhig Rayleen V. Bowman Ian A Yang Kwun M. Fong 孙岚 何建行 | 2013 | 国际病理科学与临床杂志2013，33，4： | 2 |
| 5 | Detection of micrometastases in peritoneal washings of gastric cancer patients by the reverse transcriptase polymerase chain reaction显示文摘 | Kimberly Moore Dalal Yanghee Woo Kaitlyn Kelly Charles Galanis Mithat Gonen Yuman Fong Daniel G. Coit | 2008 | Gastric Cancer2008，，4： | 2 |
| 6 | Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B显示文摘 | Man-Fung Yuen Yasuhito Tanaka Daniel Yee-Tak Fong James Fung Danny Ka-Ho Wong John Chi-Hang Yuen David Yiu-Kuen But Annie On-On Chan Benjamin Chun-Yu Wong Masashi Mizokami Ching-Lung Lai | 2008 | Journal of Hepatology2008，，1： | 1 |
| 7 | Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B显示文摘 | Man-Fung Yuen Yasuhito Tanaka Daniel Yee-Tak Fong James Fung Danny Ka-Ho Wong John Chi-Hang Yuen David Yiu-Kuen But Annie On-On Chan Benjamin Chun-Yu Wong Masashi Mizokami Ching-Lung Lai | 2008 | Journal of Hepatology2008，，1： | 1 |
| 8 | Hong Kong Baccalaureate Nursing Students’ Stress and Their Coping Strategies in Clinical Practice显示文摘 | Christine K.L. Chan Winnie K.W. So Daniel Y.T. Fong | 2009 | Journal of Professional Nursing2009，，5： | 1 |
| 9 | A Fuzzy Substroke Extractor For Handwritten Chinese Characters显示文摘 | Fong H S | 1996 | Pattern Recognition1996，29，12： | 1 |
| 10 | 1α,25(OH) 2 -Dihydroxyvitamin D 3 /VDR protects the skin from UVB-induced tumor formation by interacting with the β-catenin pathway显示文摘 | Yan J. Jiang Arnaud E. Teichert Frankie Fong Yuko Oda Daniel D. Bikle | 2013 | Journal of Steroid Biochemistry and Molecular Biology2013，，： | 1 |
| 11 | The influence of positive peritoneal cytology on survival in patients with pancreatic adenocarcinoma显示文摘 | Cristina R. Ferrone M.D. Barbara Haas M.D. Laura Tang M.D. Daniel G. Coit M.D. Yuman Fong M.D. Murray F. Brennan M.D. Peter J. Allen M.D | 2006 | Journal of Gastrointestinal Surgery2006，，10： | 1 |
| 12 | ISSLS Prize Winner: Prevalence, Determinants, and Association of Schmorl Nodes of the Lumbar Spine With Disc Degeneration: A Population-Based Study of 2449 Individuals显示文摘 | Florence P. S. Mok Dino Samartzis Jaro Karppinen Keith D. K. Luk Daniel Y. T. Fong Kenneth M. C. Cheung | 2010 | Spine2010，，： | 1 |
| 13 | RT-PCR Increases Detection of Submicroscopic Peritoneal Metastases in Gastric Cancer and Has Prognostic Significance显示文摘 | Joyce Wong Kaitlyn Kelly Arjun Mittra Mithat Gonen Peter Allen Yuman Fong Daniel Coit | 2012 | Journal of Gastrointestinal Surgery2012，，5： | 1 |
| 14 | Blood pressure is associated with body mass index in both normal and obese children 显示文摘 | Qing He Zong Yi-ding Daniel Yee-tak Fong | 2000 | Hypertension2000，36，： | 1 |
| 15 | Early is superior to deferred preemptive lamivudine therapy for hepatitis B patients undergoing chemotherapy显示文摘 | George K.K Lau Harry H.Y Yiu Daniel Y.T Fong Hoi-Ching Cheng Wing-Yan Au Lydia S.F Lai Micheal Cheung Hai-Ying Zhang Albert Lie Roger Ngan Raymond Liang | 2003 | Gastroenterology2003，，6： | 1 |
| 16 | Knowledge and attitudes regarding pain management among nurses in Hong Kong medical units显示文摘 | Liza YY Lui Winnie KW So Daniel YT Fong | 2008 | J Clin Nurs2008，17，15： | 1 |
| 17 | Early is superior to deferred preemptive lamivudine therapy for hepatitis B patients undergoing chemotherapy显示文摘 | George K.K Lau Harry H.Y Yiu Daniel Y.T Fong Hoi-Ching Cheng Wing-Yan Au Lydia S.F Lai Micheal Cheung Hai-Ying Zhang Albert Lie Roger Ngan Raymond Liang | 2003 | Gastroenterology2003，，6： | 1 |
| 18 | Using enterprise architecture standards in managing information technology显示文摘 | Wai Fong Boh Daniel Yellin | | 0，，03： | 1 |
| 19 | Prevention of pancreatic anastomotic leakage after pancreaticojejunostomy 显示文摘 | Ronnie Tung Ping Poon Siu Hung Lo Daniel Fong | 2002 | The American Journal of Surgery2002，183，： | 1 |
| 20 | RT-PCR Increases Detection of Submicroscopic Peritoneal Metastases in Gastric Cancer and Has Prognostic Significance显示文摘 | Joyce Wong Kaitlyn Jane Kelly Arjun Mittra Mithat Gonen Peter Allen Yuman Fong Daniel Coit | 2012 | Journal of Gastrointestinal Surgery2012，，5： | 1 |
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