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| 1 | DNA and histone methylation in gastric carcinogenesis显示文摘Epigenetic alterations contribute significantly to the development and progression of gastric cancer,one of the leading causes of cancer death worldwide.Epigenetics refers to the number of modifications of the chromatin structure that affect gene expression without altering the primary sequence of DNA,and these changes lead to transcriptional activation or silencing of the gene.Over the years,the study of epigenetic processes has increased,and novel therapeutic approaches that target DNA methylation and histone modifications have emerged.A greater understanding of epigenetics and the therapeutic potential of manipulating these processes is necessary for gastric cancer treatment.Here,we review recent research on the effects of aberrant DNA and histone methylation on the onset and progression of gastric tumors and the development of compounds that target enzymes that regulate the epigenome. | Danielle Queiroz Calcagno Carolina Oliveira Gigek Elizabeth Suchi Chen Rommel Rodriguez Burbano Marília de Arruda Cardoso Smith | 2013 | World Journal of Gastroenterology2013，19，8： | 14 |
| 2 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 3 | Role of mi RNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer显示文摘Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large number of upregulated oncogenic mi RNAs and downregulated tumour-suppressor mi RNAs in this type of cancer. In this review, we provide an overview of the role of mi RNAs, pointing to their potential to be useful as diagnostic and/or prognostic biomarkers in gastric cancer. Moreover, we discuss the influence of polymorphisms and epigenetic modifications on mi RNA activity. | Kelly Cristina da Silva Oliveira Taíssa Maíra Thomaz Araújo Camila Inagaki Albuquerque Gabriela Alcantara Barata Carolina Oliveira Gigek Mariana Ferreira Leal Fernanda Wisnieski Fernando Augusto Rodrigues Mello Junior André Salim Khayat Paulo Pimentel de Assumpcao Rommel Mário Rodriguez Burbano Marília Cardoso Smith Danielle Queiroz Calcagno | 2016 | World Journal of Gastroenterology2016，22，35： | 11 |
| 4 | Flexible distributed feedback lasers based on nanoimprinted cellulose diacetate with efficient multiple wavelength lasing显示文摘Here we present the assembly of novel transparent all-polymer distributed feedback(DFB)lasers.Flexible and highly transparent cellulose diacetate(CdA)was employed as substrate on which gratings with different periods were engraved by thermal nanoimprinting with high fidelity.Highly luminescent conjugated polymers(CP),poly(9,9-dioctylfluorene)(PFO),poly(9,9-dioctylfluorene-alt-benzothiadiazole)(F8BT),and a blend of F8BT and poly(3-hexylthiophene)-poly(9,9-dioctylfluorene-altbenzothiadiazole)(P3HT:F8BT)were deposited by spin coating onto the nanostructured plastic surfaces,giving rise to perpendicular single-mode lasing emission in the blue,green,and red wavelength ranges,respectively.These lasers show linewidths below 1 nm and low thresholds(≈6μJcm^(−2) for blue and red lasing emission),comparable to other state-of-the-art lasers obtained from similar optical gain materials on rigid substrates.The followed strategy is scalable and versatile,enabling the development of large area nanoimprinted DFB lasers(>1cm^(2))on plastic,which is highly relevant for applications in various markets. | José R.Castro Smirnov Ahmad Sousaraei Manuel R.Osorio Santiago Casado Jaime J.Hernández Longfei Wu Qi Zhang Ruidong Xia Daniel Granados Reinhold Wannemacher Isabel Rodriguez Juan Cabanillas-Gonzalez | 2019 | npj Flexible Electronics2019，3，1： | 2 |
| 5 | Infrared fluorescence imaging of infarcted hearts with A@S nanodots显示文摘Ag2S nano dots have already bee n dem onstrated as promisi ng n ear-i nfrared (NIR-II, 1.0-1.45 pm) emitting nan oprobes with low toxicity, high penetration and high resolution for in vivo imaging of, for example, tumors and vasculature. In this work, we have systematically investigated the pote ntial applicati on of function alized Ag2S nano dots for accurate imaging of damaged myocardium tissues after a myocardial in farction in duced by either partial or global ischemia. Ag2S nano dots surface-function alized with the an giote nsin II peptide (ATI I) have show n over 10-fold enhanced binding efficiency to damaged tissues than non-specifically (PEG) functionalized Ag2S nanodots due to their interaction with the upregulated angiotensin II receptor type I (AT1R). It is demonstrated how the NIR-II images generated by ATII-functionalized Ag2S nanodots contain valuable information about the location and extension of damaged tissue in the myocardium allowing for a proper identification of the occluded artery as well as an in direct evaluati on of the damage level. The pote ntial applicati on of Ag2S nano dots in the n ear future for in vivo imaging of myocardial infarction was also corroborated by performing proof of concept whole body imaging experiments. | Dirk H. Ortgies Angel Luis Garcia-Villalon Miriam Granado Sara Amor Emma Martin Rodriguez Harrisson DA Santos Jingke Yao Jorge Rubio-Retama Daniel Jaque | 2019 | Nano Research2019，12，4： | 2 |
| 6 | Comparison of the survival and tolerability of radioembolization in elderly vs. younger patients with unresectable hepatocellular carcinoma<!-- Doctopic: CAN -->显示文摘 | Rita Golfieri Josè Ignacio Bilbao Livio Carpanese Roberto Cianni Daniele Gasparini Samer Ezziddin Philipp Marius Paprottka Francesco Fiore Alberta Cappelli Macarena Rodriguez Giuseppe Maria Ettorre Adelchi Saltarelli Onelio Geatti Hojjat Ahmadzadehfar Ale | 2013 | Journal of Hepatology2013，，： | 2 |
| 7 | Measuring and predicting canopy nitrogen nutrition in wheat using a spectral index—The canopy chlorophyll content index (CCCI)显示文摘 | Glenn Fitzgerald Daniel Rodriguez Garry O’Leary | 2010 | Field Crops Research2010，，3： | 2 |
| 8 | Formation and fate of haloacetic acids (HAAs) within the water treatment plant显示文摘 | Manuel J. Rodriguez Jean Serodes Danielle Roy | 2007 | Water Research2007，，18： | 2 |
| 9 | 试验室研究一种新型透水性混凝土路面砖的块型设计过程显示文摘本文介绍一种专门为城市透水性路面而设计的混凝土路面砖的块型。Cantabria大学与当地一家生产企业合作,并得到地方政府的支持,其目的是在西班牙北部应用透水型路面砖作为城市可持续性排水系统。在提出多个不同外形和尺寸的块型设计方案后,根据路面开孔率、砖连锁咬合接触面和美学角度,先从理论上进行初步对比,选择一种块型——有四种不同形状的透水槽沟;然后在Cantabia大学公路试验室里进行测试,检测不同形状的开孔对路面透水性能的影响。共进行两组测试,第一组假设路面开孔存在不同堵塞状况和坡度,以确定最佳的开孔形状;第二组用选定的混凝土路面砖,分析透水性路面的水径流。根据初步试验结果,生产企业订制模型、生产了第一批新型混凝土路面砖,并已着手推向市场。新型透水性混凝土路面砖的设计研究过程经历了无数次成功和失败,本文仅为丰富技术探讨内容,无意使其成为技术导则。 | Daniel Castro J.R.Bayon Jorge Rodriguez Nelson Gonzalez-Angullo 陈义荣(译) 杜建东(校) 刘黎(校) | 2008 | 建筑砌块与砌块建筑2008，，4： | 2 |
| 10 | The Relationship Between Urban Form and Station Boardings tor Bogot(t' s BRT显示文摘 | Nieol0s Estupifi6n Daniel A Rodriguez | 2008 | Transportation Research Part A: Policy & Practice2008，42，2： | 1 |
| 11 | The transferrin recep- tor part I: Biology and targeting with cytotoxic antibodies for the treatment of cancer显示文摘 | Daniels TR Delgado T Rodriguez JA | 2006 | Clin Immunol2006，121，2： | 1 |
| 12 | W ater Research显示文摘 | Rodriguez M J Serodes J Danielle R | 2007 | 2007,41(18):4222-42322007，41，18： | 1 |
| 13 | CHIH - DFT theoretical study of isomeric thiatriazoles and their potential activity as corrosion inhihitors 显示文摘 | Luz Maria Rodriguez - Valdez Alberto Martinez - Villafane Daniel Glossman - Mintnik | 2005 | Journal of Molecular Structure:THEOCHEM2005，716，： | 1 |
| 14 | Financial systems in financial crisis — An analysis of banking systems in the EU显示文摘 | Daniel Detzer Jerome Creel Fabien Labondance Sandrine Levasseur Mimoza Shabani Jan Toporowski Judith Tyson Costanza Consolandi Giampaolo Gabbi Massimo Matthias Pietro Vozzella Carlos A. Carrasco Patricia Peinado Carlos A. Rodriguez Gonzalez | 2014 | Intereconomics2014，，2： | 1 |
| 15 | Analyzing the cost effectiveness of Santiago, Chile’s policy of using urban forests to improve air quality显示文摘 | Francisco J. Escobedo John E. Wagner David J. Nowak Carmen Luz De la Maza Manuel Rodriguez Daniel E. Crane | 2007 | Journal of Environmental Management2007，，： | 1 |
| 16 | The transferrin receptor part Ⅰ: biology and targeting with cytotoxic antibodies for the treatment of cancer显示文摘 | Daniel TR Delgado T Rodriguez JA | 2006 | Clin Imrnunol2006，121，2： | 1 |
| 17 | Measuring and predicting canopy nitrogen nutrition in wheat using a spectral index-the canopy chlorophyll content index (CCCI) 显示文摘 | Glenn Fitzgerald Daniel Rodriguez Garry O'Leary | 2010 | Field Crops Research2010，116，： | 1 |
| 18 | Formation and fate of haloacetic acids (HAAs) within the water treatment plant显示文摘 | Manuel J. Rodriguez Jean Serodes Danielle Roy | 2007 | Water Research2007，，18： | 1 |
| 19 | Changes in the Age and Education Profile of Displaced Workers 显示文摘 | Daniel Rodriguez Madeline Zavodny | 2003 | Industrialand Labor Relations Review2003，56，03： | 1 |
| 20 | The transferrin receptor part I : biology and targeting with cytotoxic antibodies for the treatment of cancer显示文摘 | Daniels T R Delgado T Rodriguez J A | 2006 | Clin Immunol2006，121，2： | 1 |
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