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| 1 | The peroxynitrite catalyst WW-85 improves microcirculation in ovine smoke inhalation injury and septic shock显示文摘 | Dirk M. Maybauer Marc O. Maybauer Csaba Szabó Martin Westphal Lillian D. Traber Andrew L. Salzman David N. Herndon Daniel L. Traber | 2011 | Burns2011，，5： | 1 |
| 2 | Cardiopulmonary effects of low-dose arginine vasopressin in ovine acute lung injury显示文摘 | Martin Westphal Sebastian Rehberg Marc O. Maybauer Dirk M. Maybauer Perenlei Enkhbaatar Beena B. Westphal-Varghese Frank C. Schmalstieg Naoki Morita Robert A. Cox Lillian D. Traber Hal Hawkins Elbert Whorton Daniel L. Traber | 2011 | Critical Care Medicine2011，，2： | 1 |
| 3 | Beneficial Effects of Concomitant Neuronal and Inducible Nitric Oxide Synthase Inhibition in Ovine Burn and Inhalation Injury显示文摘 | Matthias Lange Atsumori Hamahata Perenlei Enkhbaatar Robert A. Cox Yoshimitsu Nakano Martin Westphal Lillian D. Traber David N. Herndon Daniel L. Traber | 2011 | Shock2011，，6： | 1 |
| 4 | Impact of bronchial circulation on bronchial exudates following combined burn and smoke inhalation injury in sheep显示文摘 | Naoki Morita Perenlei Enkhbaatar Dirk M. Maybauer Marc O. Maybauer Martin Westphal Kazunori Murakami Hal K. Hawkins Robert A. Cox Lillian D. Traber Daniel L. Traber | 2010 | Burns2010，，3： | 1 |
| 5 | Biological activity of IgE specific for cross-reactive carbohydrate determinants显示文摘 | Kay Foetisch Sandra Westphal Iris Lauer Mechthild Retzek Fritz Altmann Daniel Kolarich Stephan Scheurer Stefan Vieths | 2003 | The Journal of Allergy and Clinical Immunology2003，，4： | 1 |
| 6 | 新一代风险科学的框架(续完)显示文摘5.2.5暴露评估目前,人类暴露评估主要基于人类环境中环境因素的测量水平(美国EPA,2010);某些情况下,内部剂量测量值也可能通过生物监测(Hays和Aylward,2008)或药代动力学模型(Barton等,2007)获取。在NexGen方法中,暴露评估将更侧重通过先进的生物监测技术(NRC,2012)结合新高通量方法,获得大量环境因素暴露指标(Jones等,2012),从而直接测量人类关键的毒性通路扰动。 | Daniel Krewski Margit Westphal Melvin E. Andersen Gregory M. Paoli Weihsueh A. Chiu Mustafa Al-Zoughool Maxine C. Croteau Lyle D. Burgoon Ila Cote 王晓宇 张伊人 汪源 金泰廙 | 2015 | 环境与职业医学2015，32，4： | 0 |
| 7 | 新一代风险科学的框架(待续)显示文摘[目的]2011年,美国环境保护署启动了Nex Gen项目,为下一代的风险科学建立了新的模式。[方法]Nex Gen框架建立于三个基石之上:由于基础生物学和毒理学的重要进展,人们获得了有关毒性通路的新数据;从人群健康角度来看,大多数的不良健康结局均涉及数种影响因素;重新关注新型风险评估方法,以期更好地为风险管理决策提供信息。[结果]Nex Gen框架分为三个阶段:第一阶段(目标)重点关注问题的提出和范围,将风险背景和风险管理决策可选方案纳入考虑范畴;第二阶段(风险评估)旨在运用新的毒性检测工具和技术确定关键的毒理学通路的扰动,以及采用先进的风险评估方法去更好地描述风险及其不确定性;第三阶段(风险管理)包括采用合理的风险管理决策原则,发展符合法律规范、经济效益、合理建议、以社区为基础或高技术含量的循证人群健康风险管理策略。[结论]对一系列案例研究原型的分析表明,实践中已开始采用Nex Gen框架的诸多方面。 | Daniel Krewski Margit Westphal Melvin E.Andersen Gregory M.Paoli Weihsueh A.Chiu Mustafa Al-Zoughool Maxine C.Croteau Lyle D.Burgoon Ila Cote 王晓宇 张伊人 汪源 金泰廙 | 2015 | 环境与职业医学2015，32，3： | 0 |
| 8 | Instream coliform gradients in the Holtemme, a small headwater stream in the Elbe River Basin, Northern Germany显示文摘 | Daniel KARTHE Pei-Ying LIN Katja WESTPHAL | 2017 | Frontiers of Earth Science2017，11，3： | 0 |
| 9 | Observation of a single protein by ultrafast X-ray diffraction显示文摘The idea of using ultrashort X-ray pulses to obtain images of single proteins frozen in time has fascinated and inspired many.It was one of the arguments for building X-ray free-electron lasers.According to theory,the extremely intense pulses provide sufficient signal to dispense with using crystals as an amplifier,and the ultrashort pulse duration permits capturing the diffraction data before the sample inevitably explodes.This was first demonstrated on biological samples a decade ago on the giant mimivirus.Since then,a large collaboration has been pushing the limit of the smallest sample that can be imaged.The ability to capture snapshots on the timescale of atomic vibrations,while keeping the sample at room temperature,may allow probing the entire conformational phase space of macromolecules.Here we show the first observation of an X-ray diffraction pattern from a single protein,that of Escherichia coli GroEL which at 14 nm in diameter is the smallest biological sample ever imaged by X-rays,and demonstrate that the concept of diffraction before destruction extends to single proteins.From the pattern,it is possible to determine the approximate orientation of the protein.Our experiment demonstrates the feasibility of ultrafast imaging of single proteins,opening the way to single-molecule time-resolved studies on the femtosecond timescale. | Tomas Ekeberg Dameli Assalauova Johan Bielecki Rebecca Boll Benedikt J.Daurer Lutz A.Eichacker Linda E.Franken Davide E.Galli Luca Gelisio Lars Gumprecht Laura H.Gunn Janos Hajdu Robert Hartmann Dirk Hasse Alexandr Ignatenko Jayanath Koliyadu Olena Kulyk Ruslan Kurta Markus Kuster Wolfgang Lugmayr Jannik Lübke Adrian P.Mancuso Tommaso Mazza Carl Nettelblad Yevheniy Ovcharenko Daniel E.Rivas Max Rose Amit K.Samanta Philipp Schmidt Egor Sobolev Nicusor Timneanu Sergey Usenko Daniel Westphal Tamme Wollweber Lena Worbs Paul Lourdu Xavier Hazem Yousef Kartik Ayyer Henry N.Chapman Jonas A.Sellberg Carolin Seuring Ivan A.Vartanyants Jochen Küpper Michael Meyer Filipe R.N.C.Maia | 2024 | Light(Science & Applications)2024，13，1： | 0 |
| 10 | Co-located quantitative trait loci mediate resistance to Agrobacterium tumefaciens, Phytophthora cinnamomi,and P.pini in Juglans microcarpa×J.regia hybrids显示文摘Soil-borne plant pathogens represent a serious threat that undermines commercial walnut(Juglans regia)production worldwide.Crown gall,caused by Agrobacterium tumefaciens,and Phytophthora root and crown rots,caused by various Phytophthora spp.,are among the most devastating walnut soil-borne diseases.A recognized strategy to combat soil-borne diseases is adoption of resistant rootstocks.Here,resistance to A.tumefaciens,P.cinnamomi,and P.pini is mapped in the genome of Juglans microcarpa,a North American wild relative of cultivated walnut.Half-sib J.microcarpa mother trees DJUG 31.01 and DJUG 31.09 were crossed with J.regia cv.Serr,producing 353 and 400 hybrids,respectively.Clonally propagated hybrids were genotyped by sequencing to construct genetic maps for the two populations and challenged with the three pathogens.Resistance to each of the three pathogens was mapped as a major QTL on the long arm of J.microcarpa chromosome 4D and was associated with the same haplotype,designated as haplotype b,raising the possibility that the two mother trees were heterozygous for a single Mendelian gene conferring resistance to all three pathogens.The deployment of this haplotype in rootstock breeding will facilitate breeding of a walnut rootstock resistant to both crown gall and Phytophthora root and crown rots. | Ramesh K.Ramasamy Ming-Cheng Luo Charles A.Leslie Dianne Velasco Natalia Ott Ali McClean Abhaya M.Dandekar Mallikarjuna Aradhya Patrick J.Brown Gregory T.Browne Daniel A.Kluepfel Andreas Westphal Jan Dvorak | 2021 | Horticulture Research2021，8，1： | 0 |
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