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| 1 | Staging accuracy of esophageal cancer by endoscopic ultrasound:A meta-analysis and systematic review显示文摘AIM: To evaluate the accuracy of endoscopic ultrasound (EUS) in the staging of esophageal cancer. METHODS: Only EUS studies confirmed by surgery were selected. Articles were searched in Medline and Pubmed. Two reviewers independently searched and extracted data. Meta-analysis of the accuracy of EUS was analyzed by calculating pooled estimates of sensitivity, specificity, likelihood ratios, and diagnostic odds ratio. Pooling was conducted by both the Mantel-Haenszel method (fixed effects model) and DerSimonian Laird method (random effects model). The heterogeneity of studies was tested using Cochran’s Q test based upon inverse variance weights. RESULTS: Forty-nine studies (n = 2558) which met the inclusion criteria were included in this analysis. Pooled sensitivity and specificity of EUS to diagnose T1 was 81.6% (95% CI: 77.8-84.9) and 99.4% (95% CI: 99.0-99.7), respectively. To diagnose T4, EUS had a pooled sensitivity of 92.4% (95% CI: 89.2-95.0) and specificity of 97.4% (95% CI: 96.6-98.0). With Fine Needle Aspiration (FNA), sensitivity of EUS to diagnose N stage improved from 84.7% (95% CI: 82.9-86.4) to 96.7% (95% CI: 92.4-98.9). The P value for the χ2 test of heterogeneity for all pooled estimates was > 0.10. CONCLUSION: EUS has excellent sensitivity and specificity in accurately diagnosing the TN stage of esophageal cancer. EUS performs better with advanced (T4) than early (T1) disease. FNA substantially improves the sensitivity and specificity of EUS in evaluating N stage disease. EUS should be strongly considered for staging esophageal cancer. | Srinivas R Puli Jyotsna BK Reddy Matthew L Bechtold Daphne Antillon Jamal A Ibdah Mainor R Antillon | 2008 | World Journal of Gastroenterology2008，14，10： | 55 |
| 2 | Endoscopic ultrasound:It’s accuracy in evaluating mediastinal lymphadenopathy? A meta-analysis and systematic review显示文摘AIM:To evaluate the accuracy of endoscopic ultrasound (EUS), EUS-fine needle aspiration (FNA) in evaluating mediastinal lymphadenopathy. METHODS:Only EUS and EUS-FNA studies confirmed by surgery or with appropriate follow-up were selected. Articles were searched in Medline, Pubmed, and Cochrane control trial registry. Only studies from which a 2 × 2 table could be constructed for true positive, false negative, false positive and true negative values were included. Two reviewers independently searched and extracted data. The differences were resolved by mutual agreement. Meta-analysis for the accuracy of EUS was analyzed by calculating pooled estimates of sensitivity, specificity, likelihood ratios, and diagnostic odds ratios. Pooling was conducted by both Mantel-Haenszel method (fixed effects model) and DerSimonian Laird method (random effects model). The heterogeneity of studies was tested using Cochran’s Q test based upon inverse variance weights. RESULTS:Data was extracted from 76 studies (n = 9310) which met the inclusion criteria. Of these, 44 studies used EUS alone and 32 studies used EUS-FNA. FNA improved the sensitivity of EUS from 84.7% (95% CI:82.9-86.4) to 88.0% (95% CI:85.8-90.0). With FNA, the specificity of EUS improved from 84.6% (95% CI:83.2-85.9) to 96.4% (95% CI:95.3-97.4). The P forchi-squared heterogeneity for all the pooled accuracy estimates was > 0.10. CONCLUSION:EUS is highly sensitive and specific for the evaluation of mediastinal lymphadenopathy and FNA substantially improves this. EUS with FNA should be the diagnostic test of choice for evaluating mediastinal lymphadenopathy. | Srinivas R Puli Jyotsna Batapati Krishna Reddy Matthew L Bechtold Jamal A Ibdah Daphne Antillon Shailender Singh Mojtaba Olyaee Mainor R Antillon | 2008 | World Journal of Gastroenterology2008，14，19： | 10 |
| 3 | Urinary biomarkers for prostate cancer: a review显示文摘尽管测试的前列腺特定的抗原(PSA ) 无疑增加了的浆液的平淡的使用前列腺癌症(PCa ) 察觉,它的主要缺点之一是它特性的缺乏。作为后果,许多人为懒惰的瘤经历不必要的活体检视或治疗。PCa 特定的标记为疾病和一个前列腺瘤的攻击性的预言的早察觉被需要。因为 PCa 是异构的疾病,瘤标记的一块面板为更精确的诊断是基本的。几 biomarkers 由于他们为在组织的疾病的特性是有希望的。然而,织物是象一个可能的屏蔽工具不合适。因为尿能容易以一种非侵略的方式被获得,它是为测试的 biomarker 的有希望的底层。这篇文章为在尿的 PCa 的非侵略的测试考察 biomarkers。 | Daphne Hessels Jack A Schalken | 2013 | Asian Journal of Andrology2013，15，3： | 5 |
| 4 | Genomic imprinting in plants:the epigenetic version of an Oedipus complex显示文摘 | DAPHNE A WILSON H M JEAN-PHILIPPE VIELLE-CALZADA | 2005 | Current Opinion in Plant Biology2005，8，： | 1 |
| 5 | Visible-light activated titania perovskite photocatalysts:characterization and initial activity studies显示文摘 | Daphne Q F Tedi H Adesoji A | 2005 | Catal Commun2005，6，4： | 1 |
| 6 | PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor(VEGF) mRNA expression in human glioblastoma cells by transactivating the proximal VEGF promoter 显示文摘 | Nabendu P ShuangL Daphne A | 2003 | Cancer Res2003，63，： | 1 |
| 7 | Identification of components of the murine histone deacetylase 6 complex:link between acetylation and ubiquitination signaling pathways显示文摘 | Daphné SB Verdel A Curtet S | 2001 | Mol Cell Biol2001，21，： | 1 |
| 8 | Vitamin D status partly explains ethnic differences in blood pressure: the ‘Surinamese in the Netherlands: study on ethnicity and health’显示文摘 | Nupur R. Kohli Irene G.M. Van Valkengoed Mary Nicolaou Lizzy M. Brewster Daphne L. Van Der A Karien Stronks Marieke B. Snijder | 2012 | Journal of Hypertension2012，，8： | 1 |
| 9 | Facial nerve anatomy 显示文摘 | DAPHNE A B BARRY M S DAPHNE A B | 2003 | Medicine2003，6，1： | 1 |
| 10 | Chicken dendritic cells are susceptible to highly pathogenic avian influenza viruses which induce strong cytokine responses 显示文摘 | Lonneke V Sylvia S Daphne A | 2013 | Developmental & Comparative Immunology2013，39，3： | 1 |
| 11 | Open Diaphyseal Long Bone Fractures: A Reduction Method Using Devitalized or Extruded Osseous Fragments显示文摘 | David P Barei Lisa A Taitsman Daphne Beingessner Robert P Dunbar Sean E Nork | 2007 | Journal of Orthopaedic Trauma2007，，： | 1 |
| 12 | Radiation intracranial germ cell H,Missett therapy for tumors显示文摘 | Daphne A Kogan BT et a/ | 2003 | Int J Radiat Oncol Biol Phys2003，56，： | 1 |
| 13 | Preparation and characterization of pH-responsive poly(metharylic acid-g-ethylene gly-col) nanospheres显示文摘 | Daphne N Robinson Nicholas A | 2002 | Macromolecules2002，35，9： | 1 |
| 14 | Dietary fiber and subsequent changes in body weight and waist circumference in European men and women显示文摘 | DU HUAIDONG DAPHNE L VAN DER A HENDRIEK C BOSHUIZEN | 2010 | AmJ Clin Nutr2010，，91： | 1 |
| 15 | Cellular Pathways Regulating Responses to Compatible and Self-Incompatible Pollen in Brassica and Arabidopsis Stigmas Intersect at Exo70A1, a Putative Component of the Exocyst Complex(W)显示文摘 | Samuel Marcus A Chong Yolanda T Haasen Katrina E Aldea-Brydges May Grace Stone Sophia L Goring Daphne R | 2009 | Plant Cell2009，，9： | 1 |
| 16 | Pollen and stigma structure and function: The role of diversity in pollination 显示文摘 | Edlund A F Robert S Daphne P | 2004 | Plant Cell2004，16，： | 1 |
| 17 | Effects of temperature and oxygen concentration on geosmin production by Streptomyces tendae and Penicillium expansum 显示文摘 | CHRISTOPHER P D DAPHNE A I | 1994 | J Agric Food Chem1994，42，： | 1 |
| 18 | Mate-rial Properties of Nanoclay PVC Composites显示文摘 | Walid H A Gunter geyer Daphne Benderly | 2009 | Polymer2009，50，： | 1 |
| 19 | New targets for therapy in prostate cancer: differential display code 3 ( DD3 ( PCA3 ) ) , a highly prostate cancer-specific gene 显示文摘 | Sehalken ]A Daphne H Gerald V | 2003 | Urology2003，62，5： | 1 |
| 20 | Epidermal growth factor receptor,protein kinase B/Akt,and glioma response to erlotinib显示文摘 | DAPHNE A HAAS-KOGAN MICHAEL D | 2005 | J Natl Cancer Inst2005，97，12： | 1 |
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