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| 1 | Confocal endomicroscopy and cyst fluid molecular analysis: Comprehensive evaluation of pancreatic cysts显示文摘Increases in the quality as well as utilization of cross-sectional imaging have led to rising diagnoses of pancreatic cystic lesions(PCL). Accurate presurgical diagnosis enables appropriate triage of PCLs. Unfortunately, current diagnostic approaches have suboptimal accuracy and may lead to unnecessary surgical resections or missed diagnoses of advanced neoplasia. Additionally, early detection represents an opportunity for intervention to prevent the progression to pancreatic adenocarcinoma. Our aim for this review is to systematically review the current literature on confocal endomicroscopy and molecular biomarkers in the evaluation of PCLs. Confocal laser endomicroscopy is a novel technology that allows for real-time in vivo microscopic imaging with multiple clinical trials identifying characteristic endomicroscopy findings of various pancreatic cystic lesions. DNA-based molecular markers have also emerged as another diagnostic modality as the pattern of genetic alternations present in cyst fluid can provide both diagnostic and prognostic data. We propose that both techniques can be utilized to improve patient outcomes. | Feng Li Ahmad Malli Zobeida Cruz-Monserrate Darwin L Conwell Somashekar G Krishna | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，1： | 2 |
| 2 | A randomized, double blind study of interleukin 10 for the prevention of ERCP-induced pancreatitis显示文摘 | John A Dumot Darwin L Conwell Gregory Zuccaro John J Vargo Steven S Shay Kirk A Easley Jeffrey L Ponsky | 2001 | The American Journal of Gastroenterology2001，，7： | 2 |
| 3 | Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association's strategic Impact Goal through 2020 and beyond 显示文摘 | Lloyd-Jones D M Ynling H Darwin L | 2010 | Circulation2010，121，4： | 1 |
| 4 | Twitter usage in the fortune 50:A marketing opportunity显示文摘 | Case Carl J King Darwin L | | 0，，3： | 1 |
| 5 | 猪场空气过滤的田间试验:结果与费用显示文摘 | Darwin L R | 2009 | 饲料与饲养技术简讯2009，，09： | 1 |
| 6 | Jackson Pratt drain uid-to-serum bilirubin concentration ratio for the diagnosis of bile leaks显示文摘 | Darwin P Goldberg E Uradomo L | 2010 | Gastrointest Endosc2010，71，： | 1 |
| 7 | LFRD for steel and composite beams with web openings 显示文摘 | Darwin D Warren K L | 1990 | Journal of Structural Engineering1990，116，6： | 1 |
| 8 | Molecular basis of the interaction of Salmonella with the intestinal mucosa显示文摘 | Darwin K H Miller V L | 1999 | Clin Microbiol Rev1999，12，3： | 1 |
| 9 | A randomized, double blind study of interleukin 10 for the prevention of ERCP-induced pancreatitis显示文摘 | John A Dumot Darwin L Conwell Gregory Zuccaro John J Vargo Steven S Shay Kirk A Easley Jeffrey L Ponsky | 2001 | The American Journal of Gastroenterology2001，，7： | 1 |
| 10 | Effect of Epoxy Coating Thickness on Bond Strength of Reinforcing Bars 显示文摘 | Miller G G Kepler J L Darwin D | 2003 | ACI Structural Journal2003，100，3： | 1 |
| 11 | Regulation and sequence of the structural gene for cytochrome C552 from Escherichia coli -- not a hexahaem but a 50 kD tetrahaem nitrite reductase显示文摘 | Darwin A Hussain H Griffiths L | 1993 | Molecular Microbiology1993，9，6： | 1 |
| 12 | A first-principles examination of conducting monolayer 1T-MX2 (M=Mo, W; X=S, Se,Te): promising catalysts for hydrogen evolution reaction and its enhancement by strain显示文摘 | DARWIN B P SHI-HSIN L JER-LAI K | 2015 | Phys Chem Chem Phys2015，，： | 1 |
| 13 | The accessibility and acceptability of self-management support interventions for men with long term conditions:a systematic review and meta-synthesis of qualitative studies显示文摘 | Galdas P Darwin Z Kidd L | 2014 | BMC Public Health2014，14，： | 1 |
| 14 | Effect of pancreatic endotherapy on quality of life in chronic pancreatitis patients:A systematic review显示文摘BACKGROUND Pancreatic endotherapy provides treatment options for the management of chronic pancreatitis-related structural complications such as pancreatic duct stones,strictures,and pancreatic fluid collections.Most studies detailing endotherapy,however,have focused on technical success outcomes such as stone clearance or stricture resolution.AIM To review the effect of pancreatic endotherapy on patient-centered outcomes.METHODS Systematic review of studies examining pancreatic endotherapy.RESULTS A total of 13 studies including 3 randomized clinical trials were included.The majority of studies found an improvement in quality of life with pancreatic endotherapy.CONCLUSION While pancreatic endotherapy does appear to improve quality of life,there are clear gaps in knowledge regarding many pancreatic endotherapy modalities.Furthermore,qualitative analysis is lacking in these studies and further work is needed to elucidate the patient experience with pancreatic endotherapy. | Samuel Y Han Georgios I Papachristou Raj J Shah Darwin L Conwell | 2021 | World Journal of Gastrointestinal Endoscopy2021，13，8： | 1 |
| 15 | Micro total analysis systems I: Introduction, theory, and technology显示文摘 | Darwin R R Dimitri L Pierre-Alain A | 2002 | Anal Chem2002，74，： | 1 |
| 16 | Association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants and risk for depression during pregnancy and post-partum显示文摘 | Engineer N Darwin L Nishigandh D | 2013 | J Psychiatr Res2013，47，9： | 1 |
| 17 | Molecular basis of the interaction of Salmonella with the intestinal mucosa显示文摘 | DARWIN K H MILLER V L | 1999 | Clinical Microbiology Reviews1999，12，3： | 1 |
| 18 | Graded-density reservoirs for accessing high stress low temperature material states显示文摘 | RAYMOND F S THOMAS L K DARWIN H | 2007 | Astro- phys Space Sci2007，307，13： | 1 |
| 19 | Molecular basis of the interaction of- Salmonella with the intestinal mueosa显示文摘 | Darwin K H Miller V L | 1999 | Clin Mierobiol Rev1999，12，： | 1 |
| 20 | Development length criteria for conventional and high relative rib area reinforcing bars显示文摘 | Darwin D Zuo Jun Tholen M L | | 0，，03： | 1 |
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