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| 1 | 医学专业本科留学生教育限制性因素调查分析及对策建议显示文摘目的对留学生医学教育发展的限制性因素进行调查。方法2011至2013年对重庆医科大学350名在校留学生进行现场问卷调查,回收有效答卷339份。结果调查发现,仅有33.0%(112人)的学生认为授课教师英语表达较为顺畅,70.2%(238人)的学生有增加中文课的需求。另外,被调查学生中认为理论知识教育不够以及动手机会太少的分别占69.6%(236人)和63.1%(214人)。92.3%(313人)的学生来自东南亚地区等发展中国家。86.1%(292人)的学生认为学校对其管理不足。结论通过此次调查发现。影响留学生医学教育发展的因素主要有语言水平与需求不平衡、专业知识教育及实践不足、生源问题以及日常管理中的困难等。 | 谭继翔 张丹 赵林 刘景仑 王栋 Islam Mohammed Aftab Chouhan Dawood Siddiqui | 2016 | 中华医学教育探索杂志2016，15，2： | 14 |
| 2 | Factors affecting the seismic behavior of segmental precast bridge columns显示文摘这张手稿讨论潜在地影响部分预制 tensioned 以后桥墩的侧面的地震反应的设计参数。墩由有通过管的同心的腱的在其它上的叠的在扔期间在片断做了的预制的圆形的生气的节片断组成。墩的最底的片断在钢试管被装入箱内提高韧性并且最小化损坏。一个 FE 模型被用来调查不同设计参数并且他们怎么影响墩的侧面的力量排水量反应。调查的设计参数作为腱收益压力的一个百分比包括了起始的 tensioning 以后压力,水泥上的应用轴的压力作为精力 dissipaters 由于 tensioning 以后,墩方面比率,构造细节,钢试管厚度,和内部低碳钢 rebar 增加了。基于介绍的数据,在它的收益应力的 40%60% 的范围的一个起始的腱压力和约 20% 水泥特征强度的水泥上的起始的轴的应力为很典型的图案是适当的。这些设计价值将阻止腱让步直到侧面的飘移角度到达约 4.5% 。改变两个的钢试管厚度,高度,或联合证明了是可以被用来在一个特定的地震地区到达目标表演水平的一个有效参数。 | Haitham DAWOOD Mohamed ELGAWADY Joshua HEWES | 2014 | Frontiers of Structural and Civil Engineering2014，8，4： | 13 |
| 3 | In vitro total phenolics,flavonoids contents and antioxidant activity of essential oil,various organic extracts from the leaves of tropical medicinal plant Tetrastigma from Sabah显示文摘Objective:To detect the in vitro total phenolics,flavonoids contents and antioxidant activity of essential oil,various organic extracts from the leaves of tropical medicinal plant Tetrastigma from Sabah.Methods:The dry powder leaves of Tetrastigma were extracted with different organic solvent such as hexane.ethyl acetate,chloroform,butanol and aqueous methanol.The total phenolic and total flavonoids contents of the essential oil and various organic extracts such as hexane,ethyl acetate,chloroform,butanol and aqueous ethanol were determined by Folin-Ciocalteu method and the assayed antioxidant activity was determined in vitro models such as antioxidant capacity by radical scavenging activity usingα,α-diphenyl-β-picrylhydrazyl (DPPH) method.Results:The total phenolic contents of the essential oil and different extracts as gallic acid equivalents were found to be highest in methanol extract(386.22 mg/g) followed by ethyl acetate(190.89 mg/g).chloroform(175.89 mg/g).hexane(173.44 mg/g).and Imtanol extract (131.72 mg/g) and the phenolic contents not detected in essential oil.The antioxidant capacity of the essential oil and different extracts as ascorbic acid standard was in the order of methanol extract>ethyl acetate extract>chloroform>butanol>hexane extract also the antioxidant activity was not detected in essential oil.Conclusions:The findings show that the extent of antioxidant activity of the essential oil and all extracts are in accordance with the amount of phenolics present in that extract.Leaves of Tetrastigma being rich in phenolics may provide a good source of antioxidant. | M Amzad Hossain Muhammad Dawood Shah Charles Gnanaraj Muhammad Iqbal | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，9： | 9 |
| 4 | Urinary nuclear magnetic resonance spectroscopy of a Bangladeshi cohort with hepatitis-B hepatocellular carcinoma: A biomarker corroboration study显示文摘AIM: To establish if a distinct urinary metabolic profile could be identified in Bangladeshi hepatitis-B hepatocellular carcinoma(HCC) patients compared to cirrhosis patients and controls. METHODS: Urine samples from 42 Bangladeshi patients with HCC(39 patients with hepatitis-B HCC), 47 with cirrhosis on a background of hepatitis B, 46 with chronic hepatitis B, and seven ethnically-matched healthy controls were analyzed using nuclear magnetic resonance(NMR) spectroscopy. A full dietary and medication history was recorded for each subject. The urinary NMR data were analyzed using principal component analysis(PCA) and orthogonal partial leastsquared discriminant analysis(OPLS-DA) techniques. Differences in relative signal levels of the most discriminatory metabolites identified by PCA and OPLSDA were compared between subject groups using an independent samples Kruskal-Wallis one-way analysis of variance(ANOVA) test with all pairwise multiple comparisons. Within the patient subgroups, the MannWhitney U test was used to compare metabolite levels depending on hepatitis B e-antigen(HBe Ag) status and treatment with anti-viral therapy. A BenjaminiHochberg adjustment was applied to acquire the level of significance for multiple testing, with a declared level of statistical significance of P < 0.05.RESULTS: There were significant differences in age(P < 0.001), weight(P < 0.001), and body mass index(P < 0.001) across the four clinical subgroups. Serum alanine aminotransferase(ALT) was significantly higher in the HCC group compared to controls(P < 0.001); serum α-fetoprotein was generally markedly elevated in HCC compared to controls; and serum creatinine levels were significantly reduced in the HCC group compared to the cirrhosis group(P = 0.004). A threefactor PCA scores plot showed clustering of the urinary NMR spectra from the four subgroups. Metabolites that contributed to the discrimination between the subgroups included acetate, creatine, creatinine, dimethyamine(DMA), formate, glycine, hippurate, and trimethylamine-N-oxide(TMAO). A comparison of relative metabolite levels confirmed that carnitine was significantly increased in HCC; and creatinine, hippurate, and TMAO were significantly reduced in HCC compared to the other subgroups. HBe Ag negative patients showed a significant increase in creatinine(P = 0.001) compared to HBe Ag positive patients in the chronic hepatitis B subgroup, whilst HBe Ag negative patients showed a significant decrease in DMA(P = 0.004) in the cirrhosis subgroup compared to HBe Ag positive patients. There were no differences in metabolite levels in HCC patients who did or did not receive antiviral treatment. CONCLUSION: Urinary NMR changes in Bangladeshi HCC were identified, corroborating previous findings from Egypt and West Africa. These findings could form the basis for the development of a cost-effective HCC dipstick screening test. | I Jane Cox Abil E Aliev Mary ME Crossey Mahvish Dawood Mamun Al-Mahtab Sheikh M Akbar Salimur Rahman Antonio Riva Roger Williams Simon D Taylor-Robinson | 2016 | World Journal of Gastroenterology2016，22，16： | 4 |
| 5 | Tumor necrosis factor-α-G308A polymorphism is associated with liver pathological changes in hepatitis C virus patients显示文摘AIM To investigate the association of tumor necrosis factor alpha(TNFα)-G308 A polymorphism with different liver pathological changes in treatment-na?ve Egyptian patients infected with hepatitis C virus(HCV) genotype 4.METHODS This study included 180 subjects,composed of 120 treatment-na?ve chronic HCV patients with different fibrosis grades(F0-F4) and 60 healthy controls. The TNFα-G308 A region was amplified by PCR and the different genotypes were detected by restriction fragment length polymorphism analysis. The TNFα protein was detected by enzyme-linked immunosorbent assay. The influence of different TNFα-G308 A genotypes on TNFα expression and liver disease progression were statistically analyzed. The OR and 95%CI were calculated to assess the relative risk confidence.RESULTS Current data showed that the TNFα-G308 A SNP frequency was significantly different between controls and HCV infected patients(P = 0.001). Both the AA genotype and A allele were significantly higher in late fibrosis patients(F2-F4,n = 60) than in early fibrosis patients(F0-F1,n = 60)(P = 0.05,0.04 respectively). Moreover,the GA or AA genotypes increased the TNFα serum level greater than the GG genotype(P = 0.002). The results showed a clear association between severe liver pathological conditions(inflammation,steatosis and fibrosis) and(GA + AA) genotypes(P = 0.035,0.03,0.04 respectively). The stepwise logistic regression analysis showed that the TNFα genotypes(GA + AA) were significantly associated with liver inflammation(OR = 3.776,95%CI: 1.399-10.194,P = 0.009),severe steatosis(OR = 4.49,95%CI: 1.441-14.0,P = 0.010) and fibrosis progression(OR = 2.84,95%CI: 1.080-7.472,P = 0.034). Also,the A allele was an independent risk factor for liver inflammation(P = 0.003),steatosis(P = 0.003) and fibrosis(P = 0.014). CONCLUSION TNFα SNP at nucleotide-308 represents an important genetic marker that can be used for the prognosis of different liver pathological changes in HCV infected | Noha G Bader El Din Sally Farouk Reem El-Shenawy Marwa K Ibrahim Reham M Dawood Mostafa M Elhady Ahmed M Salem Naglaa Zayed Ahmed Khairy Mostafa K El Awady | 2016 | World Journal of Gastroenterology2016，22，34： | 3 |
| 6 | Hydrogenation of nanostructured semiconductors for energy conversion and storage显示文摘Nanostructured semiconductors have been researched intensively for energy conversion and storage applications in recent decades.Despite of tremendous findings and achievements,the performance of the devices resulted from the nanomaterials in terms of energy conversion efficiency and storage capacity needs further improvement to become economically viable for subsequent commercialization.Hydrogenation is a simple,efficient,and cost-effective way for tailoring the electronic and morphological properties of the nanostructured materials.This work reviews a series of hydrogenated nanostructured materials was produced by the hydrogenation of a wide range of nanomaterials.These materials with improved inherent conductivity and changed characteristic lattice structure possess much enhanced performance for energy conversion application,e.g.,photoelectrocatalytic production of hydrogen,and energy storage applications,e.g.,lithium-ion batteries and supercapacitors.The hydrogenation mechanisms as well as resultant properties responsible for the efficiency improvement are explored in details.This work provides guidance for researchers to use the hydrogenation technology to design functional materials. | Jingxia Qiu Jacob Dawood Shanqing Zhang | 2014 | Chinese Science Bulletin2014，59，18： | 2 |
| 7 | Tumor necrosis factor-mediates cardiac remodeling and ventrieular dysfunction after pressure overload state显示文摘 | Sun M Chen M Dawood F | 2007 | Circulation2007，115，11： | 1 |
| 8 | Emergence of a novel swine-origin influenza A(H1N1) virus in humans显示文摘 | Novel Swine-Origin Influenza A(H1N1) Virus investigation Team Dawood FS Jain S | 2009 | N Engl J Med2009，360，： | 1 |
| 9 | Novel swine-origin influenza A (H1N1) virus invesrigation team:emergence of a novel swine-origin influenza A(H1N1) virus in humans显示文摘 | Dawood FS Jain S Finelli L | 2009 | N Engl J Med2009，360，25： | 1 |
| 10 | Flexural strength design of concrete beams reinforced with high-strength steel bars 显示文摘 | Mast R F Dawood M Rizkalla S H | 2008 | ACI Structural Journal2008，105，5： | 1 |
| 11 | Triple-negative breast cancer:epidemiology and ma- nagement options 显示文摘 | Dawood S | 2010 | Drugs2010，70，17： | 1 |
| 12 | Tumor necrosis factor-alpha medi- ates cardiac remodeling and ventricular dysfunction after pressure overload state显示文摘 | Sun M Chen M Dawood F | 2007 | Circulation2007，，11： | 1 |
| 13 | Burden of seasonal influenza hospitalization in children, United States, 2003 to 2008显示文摘 | DAWOOD FS FIORE A KAMIMOTO L | 2010 | J Pediatr2010，157，5： | 1 |
| 14 | Emergence of a novel swine-origin influenza A (HINI) virus in humans显示文摘 | Dawood FS Jain S Finelli L | 2009 | N Engl J Med2009，360，25： | 1 |
| 15 | Multipath and ground clutter analysis for a UWB noise radar 显示文摘 | Dawood M Narayanan R M | 2002 | IEEE Transaction on Aerospace and Electronic System2002，38，3： | 1 |
| 16 | Emergence of a novel swine-origin influenza A (H1N1) virus in humans 显示文摘 | Dawood FS Jain S Finelli L | 2009 | New EnglJ Med2009，360，30： | 1 |
| 17 | Primary dysmenorrheal:advances in patho- genesis and management显示文摘 | Dawood MY | 2006 | Obstet Gynecol2006，108，2： | 1 |
| 18 | Proposed design guidelines for strengthening of steel bridges with FRP materials 显示文摘 | Schnereh D Dawood M Rizkalla S | 2007 | Construction and Building Materials2007，21，5： | 1 |
| 19 | Emergence of a novelswine-origin influenza A ( H1N1) virus in humans显示文摘 | Dawood FS Jain S Finelli L | 2009 | NEngl J Med2009，360，25： | 1 |
| 20 | Primary dysmenorrhea:advances in pathogenesis and management显示文摘 | Dawood MY | 2006 | Obstet Gynecol2006，108，： | 1 |
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