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| 1 | Treatment modalities for early gastric cancer显示文摘Different treatment modalities have been proposed in the treatment of early gastric cancer(EGC). Endoscopic resection(ER) is an established treatment that allows curative treatment, in selected cases. In addition, ER allows for an accurate histological staging, which is crucial when deciding on the best treatment option for EGC. Recently, endoscopic mucosal resection(EMR) and endoscopic submucosal dissection(ESD) have become alternatives to surgery in early gastric cancer, mainly in Asian countries. Patients with 'standard' criteria can be successfully treated by EMR techniques. Those who meet 'expanded' criteria may benefit from treatment by ESD, reducing the need for surgery. Standardized ESD training system is imperative to promulgate effective and safe ESD technique to practices with limited expertise. Although endoscopic resection is an option in patients with EGC, surgical treatment continues to be a widespread therapeutic option worldwide. In this review we tried to point out the treatment modalities for early gastric cancer. | Jesús Espinel Eugenia Pinedo Vanesa Ojeda Maria Guerra del Rio | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，12： | 11 |
| 2 | HVEM,a cosignaling molecular switch,and its interactions with BTLA,CD160 and LIGHT显示文摘Temporal and spatial expression of cosignaling receptors and their ligands regulates the early stages of T-cell activation(signal 1,T-cell receptor(TCR)signaling and signal 2,costimulation/coinhibition),clonal expansion and T-cell survival during their differentiation towards effector T cells.Once the inflammatory stimulus is eliminated,effector T cells return to homeostasis after undergoing a contraction phase by activation-induced cell death and the intervention of ligands for coinhibitory receptors,leaving a population of long-term memory T cells.The expression of ligands for coinhibitory receptors on hematopoietic cells and,more importantly,on non-hematopoietic cells of peripheral tissues is a key process in tuning the functional activity of effector T cells to prevent excess tissue inflammation that may lead to immunopathology and subsequent tissue dysfunction. | Jose Ignacio Rodriguez-Barbosa Pascal Schneider Andreas Weigert Kyung-Mi Lee Tae-Jin Kim Jose-Antonio Perez-Simon Maria-Luisa del Rio | 2019 | Cellular & Molecular Immunology2019，16，7： | 4 |
| 3 | T follicular helper expansion and humoral-mediated rejection are independent of the HVEM/BTLA pathway显示文摘贡献体液调停 allograft 拒绝的分子的小径糟糕被定义。在这研究,我们估计了在调停抗体的 allograft 拒绝的上下文表明小径的 herpesvirus 入口 mediator/B 淋巴细胞和 T 淋巴细胞衰减器(HVEM/BTLA ) 的角色。一个试验性的背景被设计阐明 HVEM/BTLA 相互作用的封锁是否能调制感应的 de novo 在接枝拒绝的功课期间招待 antidonor 特定的抗体。测试这个假设,充分 allogeneic 专业 histocompatibility 错配建筑群的皮肤接枝被移植到与适应于不同地区生活的动物控制, anti-CD40L 或发信号的 HVEM/BTLA 的调节抗体被对待的接受者老鼠的正确胁腹上小径。 CD4 的频率 T 小囊的助手( Tfh )房间( B220 ,CD4+CXCR5+ PD-1high ), extrafollicular 助手房间( B220 ,CD4+ CXCR5 PD-1+和 PD-1 )并且幼芽的中心( GC ) B 房间(B220+Fas+GL7+)被流动 cytometry 在在接枝拒绝的尖锐阶段期间在白天 10 柱子移植排干和非排干的淋巴节点分析。适应于不同地区生活的动物特定的体液的有免疫力的反应也是的主人 antidonor 估计了。而 CD40/CD40L 小径的封锁在阻止 allogeneic 是高度有效的体液的有免疫力的反应, HVEM/BTLA-interacting 小径的调停抗体的封锁影响了 Tfh 房间的既不扩大也不 GC B 房间的扩大。因而,主机 antidonor 的功课调停抗体的反应通常继续了,没有损害开发的可检测的证据。在摘要,这些数据显示 HVEM/BTLA 相互作用为 de novo 主人 antidonor 的形成是非必需的在移植的适应于不同地区生活的动物特定的抗体。 | Jose-Ignacio Rodriguez-Barbosa Carlos Fernandez-Renedo Ana Maria Bravo Moral Leo Biihler Maria-Luisa del Rio | 2017 | Cellular & Molecular Immunology2017，14，6： | 3 |
| 4 | Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78显示文摘 | Rammohan V. Rao Alyson Peel Anna Logvinova Gabriel del Rio Evan Hermel Takanori Yokota Paul C. Goldsmith Lisa M. Ellerby H.Michael Ellerby Dale E. Bredesen | 2002 | FEBS Letters2002，，2： | 2 |
| 5 | 精氨酸酶-内皮型一氧化氮合酶失衡促进慢性间歇性缺氧期间的内皮功能障碍显示文摘慢性间歇性缺氧(chronic intermittent hypoxia,CIH)是阻塞性睡眠呼吸暂停的主要特征,与血管功能损害相关,尽管其不会改变血管对一氧化氮供体的反应。该研究旨在探讨精氨酸酶是否促进CIH大鼠血管内皮功能障碍。 | 刘莉 叶鹏 Krause BJ Del Rio R Moya EA Marquez-Gutierrez M Casanello P Iturriaga R | 2015 | 中华高血压杂志2015，23，5： | 2 |
| 6 | Robust linear regression taking into account errors in the predictor and response variables 显示文摘 | del Rio F J Riu J Rius F X | 2001 | Analyst2001，126，7： | 2 |
| 7 | Comparison of pathogenic and spoilage bacterial levels on refrigerated poultry parts following treatment with trisodium phosphate 显示文摘 | DEL RIO E CAPITA R PRIETO M | 2006 | Food Microbiology2006，23，2： | 1 |
| 8 | Realization theorems for categories of graded module over semigroup- graded ring显示文摘 | Abrams G Menimi C Angel Del Rio | 1994 | CommAlgebra1994，22，13： | 1 |
| 9 | Current approaches and perspectives in human keratinocyte-based gene therapies显示文摘 | Del Rio M | 2004 | Gene therapy2004，，： | 1 |
| 10 | The cells of Cajal-Retzius: still a mystery one century after显示文摘 | Soriano E Del Rio JA | 2005 | Neuron2005，46，3： | 1 |
| 11 | Amplitude reduction in visual event-related potentials as a function of sleep deprivation 显示文摘 | Corsi CM Arce C del Rio Portilla IY | 1999 | Sleep1999，22，1： | 1 |
| 12 | Heat transfer enhancement in oscillatory flows of newtonian and viscoe lastic fluids显示文摘 | Lambert A A Cuevas S del Rio J A | 2009 | International Journal of Heat and Mass Transfer2009，52，： | 1 |
| 13 | A chemical, morphological, and electrochemical (XPS, SEM/EDX, CV, and EIS) analysis of electrochemically modified electrode surfaces of natural chalcopyrite (CuFeS2) and pyrite (FeS2) in alkaline solutions显示文摘 | VELASQUEZ P LEINEN D PASCUAL J RAMOS- BARRADO J R GREZ P GOMEZ H SCHREBLER R DEL RiO R CORDOVA R | 2005 | Journal of Physical Chemistry B2005，109，1： | 1 |
| 14 | Improving the Cercospora leaf spot management model for sugar beet in Minnesota and North Dakota 显示文摘 | Khan J Del Rio L E Nelson R | 2007 | Plant Disease2007，91，9： | 1 |
| 15 | Comparing volume {Xowth in pure and mixed stands of Pinus sylvestris and Quercus pyrenaica 显示文摘 | del Rio M Sterba H | 2009 | Annals of Forest Science2009，502，66： | 1 |
| 16 | ADC measure-ments at low and high structure with b values:insight into normalbrain clinical DWI显示文摘 | Garcia Santos JM Ordonez C Torres del Rio S | 2008 | Magn Reson Imaging2008，26，1： | 1 |
| 17 | Protective effect of Ginkgo biloba extract on liver damage by a single dose of CCl(4)in male rats显示文摘 | Chavez-Morales R M Jaramillo-Juarez F Posadas del Rio F A | 2011 | Hum Exp Toxicol2011，30，3： | 1 |
| 18 | The food contami- nant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression 显示文摘 | Pinton P Nougayrede J P Del rio J C | 2009 | Toxicol Appl Pharmacol2009，237，： | 1 |
| 19 | Ebola hemorrhagic fever in 2014: the tale of an evolving epidemic显示文摘 | Del Rio C Mehta AK Lyon GM | 2014 | Ann Intern Med2014，10，161： | 1 |
| 20 | The role of ecological theory and practice in poverty alleviation and environmental conservation 显示文摘 | DeClerck F Ingram J C Del Rio C M R | 2006 | The Ecological Society of America2006，4，10： | 1 |
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