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		题名	作者	年代	出处	被引量
	1	Effects of estrogen replacement therapy on apoptosis and vascular endothelial growth factor expression in ocular surface epithelial cells:An experimental study显示文摘AIM:To investigate the effects of estrogen replacement therapy (ERT) on apoptosis and vascular endothelial growth factor (VEGF) expression in ocular surface in an experimental rat model.· METHODS:Forty female,Wistar rats were randomized in 4 groups in the study.Subcutaneous ERT (17β-estradiol,10g/kg/day) was administered to the first group without ovariectomy and to the second group with ovariectomy for three months.Third group had only ovariectomy and fourth group had sham operation.All rats were sacrificed in estrous cycles determined by vaginal smear test and their right eyes were enucleated at the end of the third month.Enucleated eyes were analyzed by immunohistochemical method for expressions of caspase-3,bcl-2,VEGF and TUNEL assay.· RESULTS:Caspase-3 expression of conjunctival epithelium was significantly higher in group 3 than group 1 (P =0.005),and group 2 (P =0.007).TUNEL score of conjunctival epithelium was significantly higher in group 3 than group 1 (P =0.006).TUNEL score of corneal epithelium was significantly higher in group 3 than group 2 (P =0.012),and group 4 (P =0.002).There was no significant difference between groups in that bcl-2 and VEGF expressions.· CONCLUSION:We determined increased apoptosis in ocular surface epithelial cells in ovariectomized rats.ERT and endogen estrogen decreased the apoptosis,and did not result in difference in VEGF expression between the groups.Estrogen may be beneficial for the treatment of apoptosis-mediated ocular surface disorders such as dry eye.Further studies are needed on this subject for a better understanding of the role of estrogen and to provide a new insight for treatment and prevention of apoptosis-mediated ocular surface disorders.	Fatih zcura Sema Oru Dndar Emel Dikicioglu etin Nahit Beder Mehmet Dndar	2012	International Journal of Ophthalmology(English edition)2012，5，1：	7
	2	Nature of cell kinetics inpsoriatic epidermis显示文摘	Doger FK Dikicioglu E Ergin F	2007	J Cutan Pathol2007，34，3：	1
	3	Nature of cell kinetics in psoriatic epidermis 显示文摘	Doger FK Dikicioglu E Ergin F	2007	J Cutan Pathol2007，34，3：	1
	4	Reproducibility of the 1998 World Health Organization/International Society of Urologic Pathology classification of papillary urothelial neoplasms of the urinary bladder显示文摘	Kutsal Yorukoglu Burcin Tuna Emel Dikicioglu Ender Duzcan Aydin Isisag Sait Sen Ugur Mungan Ziya Kirkali	2003	Virchows Archiv2003，，6：	1
	5	Early and late effects of capsaicin pretreatment in otitis media with effusion显示文摘	Basak S Dikicioglu E Turkutanit S	2005	Otol Neu rotol2005，26，：	1
	6	Nature of cell kinetics in psoriatic epidermis 显示文摘	Doger FK Dikicioglu E Ergin F	2007	J Cutan Pathol2007，34，3：	1
	7	Multiple melanotic schwannoma显示文摘	Culhaci N Dikicioglu E Meteoglu I		0，，04：	1
	8	Biological characteristics of breast cancer at the primary tumour and the involved lymph nodes显示文摘	Dikicioglu E Barutca S Meydan N	2005	Int J Clin Pract2005，59，9：	1
	9	Biological characteristics of breast cancer at the primary tumour and the involved lymph nodes显示文摘	Dikicioglu E Barutca S Meydan N	2005	Int J Clin Pract2005，59，9：	1
	10	lmmunohistochemical findings in notalgia paresthetica显示文摘	Savk E Dikicioglu E Culhaci N	2002	Dermatology2002，204，2：	1
	11	Reproducibility of the1998 World Health Organization/International Society of UrologicPathology classification of papillary urothelial neoplasms of theurinary bladder显示文摘	Yorukoglu K Tuna B Dikicioglu E	2003	Virchows Arch2003，443，6：	1

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