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| 1 | Human bone marrow activates the Akt pathway in metastatic prostate cells through transactivation of the alpha-platelet-derived growth factor receptor 显示文摘 | Dolloff N Russell MR Loizos N | 2007 | Cancer Res2007，67，2： | 1 |
| 2 | ERK and MDM2 prey on FOXO3a 显示文摘 | Yang W Dolloff NG EI-Deiry WS | 2008 | Nat Cell Biol2008，10，2： | 1 |
| 3 | An evaluation of rational functions for pho- togrammetric restitution 显示文摘 | Dowman I Dolloff J T | 2000 | International Archives of Photogram- metry and Remote Sensing2000，19，3： | 1 |
| 4 | Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab显示文摘 | Hart LS Dolloff NG Dicker DT | 2011 | Cell Cycle2011，10，14： | 1 |
| 5 | Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab显示文摘 | HART LS DOLLOFF NG DICKER DT | 2011 | Cell Cycle2011，10，14： | 1 |
| 6 | Minimum Loss Optimization in Distribution Systems: Discrete Ascent Optimal Programming 显示文摘 | BROADWATER R P DOLLOFF P A HERDMAN T L | 1996 | Electric Power Systems Reaearch1996，36，8： | 1 |
| 7 | Riparian ecotone: A functional definition and delineation for resource assessment显示文摘 | E. S. Verry C. A. Dolloff M. E. Manning | 2004 | Water Air and Soil Pollution: Focus2004，，1： | 1 |
| 8 | CX3CR1 - fractalkine expression regulates cellular mechanisms involved in adhesion, mi- gration, and survival of human prostate cancer ceils 显示文摘 | Shulby SA Dolloff NG Stearns ME | 2004 | Cancer Res2004，64，： | 1 |
| 9 | An Evaluation of Rational Functions for Photogrammetric Restitution显示文摘 | Dowman I Dolloff J T | 2000 | International Archives of Photogrammetry and Remote Sensing2000，33，31： | 1 |
| 10 | CX3CRl-fractalkine expression regulates cellular mechanisms involved in adhesion, migration, and survival of human prostate cancer cells 显示文摘 | Shulby SA Dolloff NG Stearns ME | 2004 | Cancer Res2004，64，46： | 1 |
| 11 | An Evaluation of Rational Functions for Photogrammetric Restitution 显示文摘 | Dowman I Dolloff J T | 2000 | International Archives of Photogrammetry and Remote Sensirtg2000，33，31： | 1 |
| 12 | Riparian ecotone: a functional definition for resource assessment显示文摘 | Verry E S Dolloff C A Manning M E | 2004 | Water Air and Soil Pollution2004，4，1： | 1 |
| 13 | Human bone marrow activates the Akt pathway in metastatic prostate cells through transactivation of the alpha platelet-derived growth factor receptor显示文摘 | Dolloff NG Russell MR Loizos N | | 0，，： | 1 |
| 14 | An evaluaiton of rational functions for photogrammetric restituion显示文摘 | Dowman I Dolloff J | 2000 | International Archives of Photogrammetry and Remote Sensing2000，33，10： | 1 |
| 15 | Human colon cancer stemcells are enriched by insulin-like growth factor-1 and are sensitiveto figitumumab显示文摘 | Hart LS Dolloff NG Dicker DT | 2011 | Cell Cycle2011，10，14： | 1 |
| 16 | Riparian ecotone:a functional definition and delineation for resource assessment显示文摘 | Verry ES Dolloff CA Manning ME | 2004 | Water Air Soil Poll2004，4，1： | 1 |
| 17 | REDOX IMAGING OF THE p53-DEPENDENT MITOCHONDRIAL REDOX STATE IN COLON CANCER EX VIVO显示文摘The mitochondrial redox state and its heterogeneity of colon cancer at tissue level have not been previously reported.Nor has how p53 regulates mitochondial respi ration been measured at(deep)tissue level,presumably due to the unavailability of the technology that has sufficient spatial resolution and tissue penetration depth.Our prior work demonstrated that the mito-chondrial redox state and its intnatumor heterogeneity is associated with cancer aggressiveness in human melanoma and breast cancer in mouse models,with the more metastatic tumons exhi-bit ing localized negions of more oxidized redox state.Using the Chance redox scanner with an in-plane spatial resolution of 200 pm,we imaged the mitochondrial redox state of the wild-type p53 colon tumors(HCT116 p53 ut)and the p5-deleted colon tumors(HCT116 p53-/-)by cllcting the fuorescence si gnals of nicotinamide adenine dimucleotide(NA DH)and oxidized flavoproteins [Fp,including favin adenine dinucleotide(FAD)]from the mouse xenogmafts snap frozen at low temperature.Our results show that:(1)both tumor lines have significant degree of intratumor heterogeneity of the redox state,typically exhibiting a distinct bi modal distribution that either correlates with the spatial core-rim pattern or the“hot/oold”oxida tion-roduction patches;.(2)the p531-group is significantly more beterogencous in the mitochondrial redox state and has a more oxidized turmor core compared to the p53 wt group when the tunor sizes of the two groups are matched;(3)the tumor size dependence of the redox indices(such as Fp and Fp redox ratio)is significant in the p531-group with the larger ones being more oxidized and more hetero-geneous in their redox state,particularly more oxidized in the tumor central regions;(4)the H&E staining images of tumor soctions grossly correlate with the redox images.The present work is the first to reveal at the submillimeter scale the intratumor heterogeneity pattem of the mitochon-drial redox state in colon cancer and the first to indicate that at tissue level the mitochondial redox state is p53 dependent.The findings should assist in our understanding on colon cancer pa thology and developing new imaging biomarkers for dlinical applications. | HE N.XU MIN FENG LILY MOON NATHAN DOLLOFF WAFIKEL-DEIRY LIN Z.LI | 2013 | Journal of Innovative Optical Health Sciences2013，6，3： | 1 |
| 18 | CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion,migration,and survival of human prostate cancer cells显示文摘 | Shulby SA Dolloff NG Stearns ME | 2004 | Cancer Res2004，64，14： | 1 |
| 19 | An Evaluation of Rational Functions for Photogrammetric Restitution 显示文摘 | DOWMAN I DOLLOFF F | 2000 | International Archives of Photogrammetry and Remote Sensing2000，33，： | 1 |
| 20 | Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation显示文摘 | Dolloff N G Mayes P A Hart L S | | 0，，86： | 1 |
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