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| 1 | 循证医学论争的哲学分析(上)显示文摘首先 ,我们认为EBM的支持者对EBM的定义过于宽泛 ,甚至是空洞的 ,这正是当前的有关讨论不明朗的原因 ;对此我们提出了一种更明晰的解释 ,重新阐述EBM的含义及与其他医学方法的关系。第二 ,EBM的支持者通常依据ThomasKuhn的哲学著作来说明EBM是一种Kuhn式的“范式转化” ;我们认为 ,这种说明是一种严重的错误 ,并且使有关EBM的争论过度的偏离常轨。第三 ,我们建议以W .V .Quine的信仰之网的哲学观念来理解EBM及其与其他医学方法的关系 ,这是一种更富有成果的理解方式。基于这种理解 。 | Scott R Sehon Donald E Stanley 韩鹏 程伟 | 2004 | 医学与哲学2004，25，2： | 9 |
| 2 | ABCD^(2) risk score does not predict the presence of cerebral microemboli in patients with hyper-acute symptomatic critical carotid artery stenosis显示文摘Introduction:ABCD^(2) risk score and cerebral microemboli detected by transcranial Doppler(TCD)have been separately shown to the predict risk of recurrent acute stroke.We studied whether ABCD2 risk score predicts cerebral microemboli in patients with hyper-acute symptomatic carotid artery stenosis.Participants and methods:We studied 206 patients presenting within 2 weeks of transient ischaemic attack or minor stroke and found to have critical carotid artery stenosis(≥50% ).86 patients(age 70±1(SEM:years),58 men,83 Caucasian)had evidence of microemboli;72(84% )of these underwent carotid endarterectomy(CEA).120 patients(age 72±1 years,91 men,113 Caucasian)did not have microemboli detected;102(85% )of these underwent CEA.Data were analysed using X2 and Mann–Whitney U tests and receiver operating characteristic(ROC)curves.Results:140/206(68% :95% CI 61.63 to 74.37)patients with hyper-acute symptomatic critical carotid stenosis had an ABCD2 risk score≥4.There was no significant difference in the NICE red flag criterion for early assessment(ABCD^(2) risk score≥4)for patients with cerebral microemboli versus those without microemboli(59/86 vs 81/120 patients:OR 1.05 ABCD2 risk score≥4(95% CI 0.58 to 1.90,p=0.867)).The ABCD2 risk score was<4 in 27 of 86(31% :95% CI 21 to 41)embolising patients and in 39 of 120(31% :95% CI 23 to 39)without cerebral microemboli.After adjusting for pre-neurological event antiplatelet treatment(APT),area under the curve(AUC)of ROC for ABCD2 risk score showed no prediction of cerebral microemboli(no pre-event APT,n=57:AUC 0.45(95% CI 0.29 to 0.60,p=0.531);preevent APT,n=147:AUC 0.51(95% CI 0.42 to 0.60,p=0.804)).Conclusions:The ABCD2 score did not predict the presence of cerebral microemboli or carotid disease in over one-quarter of patients with symptomatic critical carotid artery stenosis.On the basis of NICE guidelines(refer early if ABCD2≥4),assessment of high stroke risk based on ABCD2 scoring may lead to inappropriate delay in urgent treatment in many patients. | Mahmud Saedon Charles E Hutchinson Christopher H E Imray Donald R J Singer | 2017 | Stroke & Vascular Neurology2017，2，2： | 6 |
| 3 | 循证医学论争的哲学分析(下)显示文摘 | Scott R Sehon Donald E Stanley 韩鹏 程伟 | 2004 | 医学与哲学2004，25，3： | 5 |
| 4 | A 10-year review of a minimally invasive technique for the correction of pectus excavatum显示文摘 | Donald Nuss Robert E Kelly Daniel P Croitoru Michael E Katz | 1998 | Journal of Pediatric Surgery1998，，4： | 4 |
| 5 | 基于自适应光学的视网膜单细胞光学相干层析成像技术显示文摘 | 屈军乐 Ravi S JONNAL Karen E THORN Donald T MILLER | 2004 | 生物物理学报2004，20，2： | 3 |
| 6 | Sepsis, Systemic Inflammatory Response, and Multiple Organ Dysfunction: The Mystery Continues显示文摘 | Fry Donald E | 2012 | The American Surgeon2012，，： | 2 |
| 7 | A Model and Methodology for Hardware-software Codesign显示文摘 | Donald E T Jay K A Herman S | 1993 | IEEE Design & Test of Computers1993，10，3： | 2 |
| 8 | Neurocognitive Performance in Hypertensive Patients after Spine Surgery显示文摘 | Gene T. Yocum John G. Gaudet Lauren A. Teverbaugh Donald O. Quest Paul C. McCormick E Sander Connolly Eric J. Heyer | 2009 | Anesthesiology2009，，2： | 2 |
| 9 | Acute surgical emergencies in inflammatory bowel disease显示文摘 | Dale F Berg Anil M Bahadursingh Donald L Kaminski Walter E Longo | 2002 | The American Journal of Surgery2002，，： | 2 |
| 10 | 口干及其多种原因的诊治显示文摘老年口干是由多种原因引起的常见症状。口干并非衰老的正常现象,因而有必要阐明其原因。Sj(?)gren综合征可出现口干,经唇部活检即可确诊。使用各种药物也常伴发口干,症状严重时需调整剂量或停药。本文探讨了口干的治疗方法。 | Mc Donald E 萧爽 | 1992 | 国外医学(老年医学分册)1992，13，1： | 2 |
| 11 | Community integration显示文摘 | Ross E Mitchell Donald G Reid | 2000 | Annals of Tourism Research2000，，1： | 2 |
| 12 | Heat shock response by the hyperthermophilic archaeon Pyrococcus furiosus显示文摘 | Donald E Swapnil R | 2003 | Applied and Environmental Microbiology2003，69，4： | 1 |
| 13 | Periphyton growth on submerged artificial substrate as a predictor of phytoplankton response to nutrient enrichment显示文摘 | Smoot J C Donald E L Michella L | 1998 | Journal of Microbiological Methods1998，，32： | 1 |
| 14 | 'Green revolution' genes encode mutant gibberellin response modulators显示文摘 | Peng J R Donald E R Nigel M H | 1999 | Nature1999，400，： | 1 |
| 15 | Anaerobic ammonium oxi- dation (anammox) in the marine environment 显示文摘 | Dalsgaard T Thamdrup B Donald E C | 2005 | Research in Mi- crobiology2005，156，4： | 1 |
| 16 | Paleoshoreline evidence for postglacial tilting in Southern Manitoba显示文摘 | Gary E T Donald R C Bruce G B | 1998 | Journal of Paleolin- nology1998，19，： | 1 |
| 17 | Harmonic diffractive lenses 显示文摘 | DONALD W S GARY E S | 1995 | Appl Opt1995，34，： | 1 |
| 18 | Carbohydrate based ingredient performs like fat for use in a variety of food applications 显示文摘 | Donald E Pszczola | 1989 | Food Technology1989，43，7： | 1 |
| 19 | Structured programming with go to statements显示文摘 | Knuth Donald E | 1974 | Computing Surveys1974，6，4： | 1 |
| 20 | Unique application of car-bon-carboncomposite materials(part two)显示文摘 | Donald L S Kenneth E D | 1999 | Sample Journal1999，35，4： | 1 |
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