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17篇 您的检索式:作者名="Dudman NP"
    题名 作者 年代 出处 被引量
1同型半胱氨酸增强血白细胞粘附分子的表达显示文摘用免疫萤光流式细胞仪检测同型半胱氨酸是否改变体外健康人血单核细胞 ,中性粒细胞 ,及淋巴细胞表面粘附分子CD11b ,CD18,CD14和L 选择素 (L selectin)的表达。结果显示 :同型半胱氨酸在低浓度2 0 μmol/L时明显增加CD11b和CD18在各种白细胞表面的表达 ,同时也增加了CD14在单核及中性粒细胞的表达。这种作用随同型半胱氨酸浓度升高而增强 ,但当浓度升至等于或大于 1mmol/L时 ,各种粘附分子的表达反而降低。同型半胱氨酸使各种细胞类型表面L selectin降低。此结果表明同型半胱氨酸可改变白细胞表面粘附分子的表达 ,可能在体内通过此途经导致白细胞粘附并游出血管内皮。郭雪微 Dudman NP 2001基础医学与临床2001,21,2:6
2Homocysteine enhances neutrophil- endothelial interactions in both cultured human cells and ratsin vivo 显示文摘Dudman NP Temple SE Guo XW 1999Circulation Research1999,84,4:1
3Homocysteine enhances neutrophil-endothelial interactions in both cultured human cells and rats in vivo显示文摘Dudman NP Temple SE Guo XW 1999Circ Res1999,84,4:1
4Human arterial endothelial cell detachment in vitro:Its promotion by homocysteine and cysteine显示文摘Dudman NP Hicks C Wang J 1991Atherosclerosis1991,91,:1
51H NMR determination of urinary betaine in patients with prema-ture vascular disease and mild homocysteinemia显示文摘 Dudman NP Kuchel PW 1995Clin Chem1995,41,2:1
61H NMR determination of urinary betaine in patients with premature vascular disease and mild homocysteinemia显示文摘Lundberg P Dudman NP Kuchel PW 1995Clin Chem1995,41,:1
7Homocysteine catabolism: levels of 3 enzymes in cultured human vascular endothelium and their relevance to vascular disease显示文摘Wang J Dudman NP Wilcken DE 1992Atherosclerosis1992,97,1:1
8Homocysteinemia due to cystathionine beta-synthase deficiency-the effects of betaine treatment in pyridoxine-responsive patients显示文摘 Dudman NP Tyrrell PA 1985Metabolism1985,34,:1
9Effect of serum lipopro- tein (a) on estimation of low density lipoprotein cholesterol by Friedewald formula显示文摘LI KM WILCKEN DE DUDMAN NP 1994Clin Chem1994,40,4:1
10Homocysteine enhances neutrophil-endothelial interactions in both cultured human cells and rats In vivo显示文摘 Temple SE Guo XW 1999Circ Res1999,84,4:1
111H NMR determination of urinary betaine in patients with premature vascular disease and mild homocysteinemia 显示文摘Lundberg P Dudman NP Kuchel PW 1995Clin Chem1995,41,2:1
12Leukocytes extravasation in acute homocysteinemic rats显示文摘Fu WY Dudman NP Perry MA Wang XL 2002Atherosclerosis2002,161,1:1
13Homocysteine enhances neutrophil-endothelial interactons in both cultured human cells and rats in vivo显示文摘Dudman NP Temple SE Guo XW 1999Circulation Research1999,84,4:1
14Homocysteine enhances neutrophil-endothelial interactions in both cultured human cells and rats in vivo显示文摘Dudman NP Temple SE Guo XW 1999Circ Res1999,84,4:1
15Homocystinuria-the effects of betaine in the treatment of patients not responsive to pyridoxine显示文摘Wilcken DE Wilcken B Dudman NP 1983N Engl J Med1983,309,8:1
16Homocysteine enhances neutrophil-endothelial interactions in both cultured human cells and rats In vivo显示文摘Dudman NP Temple SE Guo XW 1999Circ Res1999,84,4:1
17Leukocytes extravasation in acute homocysteinemic rats 显示文摘Fu WY Dudman NP Perry MA 2002Atherosclerosis2002,161,1:1
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