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| 1 | A unified intrinsic functional expansion theory for solitary waves显示文摘A new theory is developed here for evaluating solitary waves on water, with results of high accuracy uniformly valid for waves of all heights, from the highest wave with a corner crest of 120° down to very low ones of diminishing height. Solutions are sought for the Euler model by employing a unified expansion of the logarithmic hodograph in terms of a set of intrinsic component functions analytically determined to represent all the intrinsic properties of the wave entity from the wave crest to its outskirts. The unknown coefficients in the expansion are determined by minimization of the mean-square error of the solution, with the minimization optimized so as to take as few terms as needed to attain results as high in accuracy as attainable. In this regard, Stokes's formula, F2μπ = tanμπ, relating the wave speed (the Froude number F) and the logarithmic decrement μ of its wave field in the outskirt, is generalized to establish a new criterion requiring (for minimizing solution error) the functional expansion to contain a finite power series in M terms of Stokes's basic term (singular inμ), such that 2Mμ is just somewhat beyond unity, i.e. 2Mμ (^-) 1. This fundamental criterion is fully validated by solutions for waves Dedicated to Zhemin Zheng for celebration of his Eightieth Anniversary It gives us a great pleasure to dedicate this study to Prof. Zhemin Zheng and join our distinguished colleagues and friends for the jubilant celebration of his Eightieth Anniversary. Warmest tribute is due from us, as from many others unlimited by borders and boundaries, for his contributions of great significance to science, engineering science and engineering, his tremendous influence as a source of inspiration and unerring guide to countless workers in the field, his admirable leadership in fostering the Institute of Mechanics of world renown, as well as for his untiring endeavor in promoting international interaction and cooperation between academies of various nations.of various amplitude-to-water depth ratio α = a/h, especially about α (~!) 0.01, at which M = 10 by the criterion.In this pursuit, the class of dwarf solitary waves, defined for waves with α≤ 0.01, is discovered as a group of problems more challenging than even the highest wave. For the highest wave, a new solution is determined here to give the maximum height αhst = 0.8331990, and speed Fhst = 1.290890, accurate to the last significant figure, which seems to be a new record. | Theodore Yaotsu Wu John Kao Jin E.Zhang | 2005 | Acta Mechanica Sinica2005，21，1： | 3 |
| 2 | Topological evolution of coexpression networks by new gene integration maintains the hierarchical and modular structures in human ancestors显示文摘We analyze the global structure and evolution of human gene coexpression networks driven by new gene integration. When the Pearson correlation coefficient is greater than or equal to 0.5, we find that the coexpression network consists of 334 small components and one 'giant' connected subnet comprising of 6317 interacting genes. This network shows the properties of power-law degree distribution and small-world. The average clustering coefficient of younger genes is larger than that of the elderly genes(0.6685 vs. 0.5762). Particularly, we find that the younger genes with a larger degree also show a property of hierarchical architecture. The younger genes play an important role in the overall pivotability of the network and this network contains few redundant duplicate genes. Moreover, we find that gene duplication and orphan genes are two dominant evolutionary forces in shaping this network. Both the duplicate genes and orphan genes develop new links through a 'rich-gets-richer'mechanism. With the gradual integration of new genes into the ancestral network, most of the topological structure features of the network would gradually increase. However, the exponent of degree distribution and modularity coefficient of the whole network do not change significantly, which implies that the evolution of coexpression networks maintains the hierarchical and modular structures in human ancestors. | Jian Zu Yuexi Gu Yu Li Chentong Li Wenyu Zhang Yong E.Zhang UnJin Lee Li Zhang Manyuan Long | 2019 | Science China(Life Sciences)2019，62，4： | 3 |
| 3 | Successful Liver Transplantation Following Medical Management of Portopulmonary Hypertension: A Single‐Center Series显示文摘 | N.Sussman V.Kaza N.Barshes R.Stribling J.Goss C.O’Mahony E.Zhang J.Vierling A.Frost | 2006 | American Journal of Transplantation2006，，9： | 1 |
| 4 | Testing range estimators of historical volatility显示文摘 | JinghongShu Jin E.Zhang | 2006 | J Fut Mark2006，，3： | 1 |
| 5 | Tangential and Vertical Compact Torus Injection Experiments on the STOR-M Tokamak显示文摘This paper describes the setup and results of compact torus (CT) injection experiments on the STOR-M tokamak. Tangential CT injection into STOR-M induced H-mode-like phenomena including doubling the electron density, reduction in the Ha radiation level, suppression of the floating potential fluctuations, suppression of the m = 2 Mirnov oscillations, and increase in the global energy confinement time. Experimental setup, bench-test results, and some preliminary injection data for vertical CT injection experiments on STOR-M will be shown. In addition, numerical simulations of the CT trajectories in tokamak discharges for both tangential and vertical injection geometries will be discussed. | 肖持进 S.Livingstone A.K.Singh E.Zhang A.Hirose | 2005 | Plasma Science and Technology2005，7，2： | 1 |
| 6 | Acrossocheilus spinifer, a new species of barred cyprinid fish from south China (Pisces: Teleostei)显示文摘 | L. Y.Yuan Z. Q.Wu E.Zhang | 2006 | Journal of Fish Biology (SB)2006，，： | 1 |
| 7 | EyeHealer:A large-scale anterior eye segment dataset with eye structure and lesion annotations显示文摘Anterior segment eye diseases account for a significant proportion of presentations to eye clinics worldwide,including diseases associated with corneal pathologies,anterior chamber abnormalities(e.g.blood or inflammation),and lens diseases.The construction of an automatic tool for segmentation of anterior segment eye lesions would greatly improve the efficiency of clinical care.With research on artificial intelligence progressing in recent years,deep learning models have shown their superiority in image classification and segmentation.The training and evaluation of deep learning models should be based on a large amount of data annotated with expertise;however,such data are relatively scarce in the domain of medicine.Herein,the authors developed a new medical image annotation system,called EyeHealer.It is a large-scale anterior eye segment dataset with both eye structures and lesions annotated at the pixel level.Comprehensive experiments were conducted to verify its performance in disease classification and eye lesion segmentation.The results showed that semantic segmentation models outperformed medical segmentation models.This paper describes the establishment of the system for automated classification and segmentation tasks.The dataset will be made publicly available to encourage future research in this area. | Wenjia Cai Jie Xu Ke Wang Xiaohong Liu Wenqin Xu Huimin Cai Yuanxu Gao Yuandong Su Meixia Zhang Jie Zhu Charlotte L.Zhang Edward E.Zhang Fangfei Wang Yun Yin Iat Fan Lai Guangyu Wang Kang Zhang Yingfeng Zheng | 2021 | Precision Clinical Medicine2021，4，2： | 0 |
| 8 | 反义长链非编码RNA调控基因表达和多能干细胞分化显示文摘高等真核生物基因组的广泛转录产生了大量的长链非编码RNA(lncRNA),它们不具有编码蛋白的功能。目前人们对它们的了解还非常有限,lncRNA被认为是生物学中的暗物质。LncRNA的功能分类及预测,是非编码RNA领域一直追寻和探索的重要问题,它对于认识非编码RNA生物学功能和存在的意义具有重要作用。 | Sai Luo J.Yuyang Lu Lichao Liu Yafei Yin Chunyan Chen Xue Han Bohou Wu Ronggang Xu Wei Liu Pixi Yan Wen Shao Zhi Lu Haitao Li Jie Na Fuchou Tang Jianlong Wang Yong E.Zhang 沈晓骅 | 2017 | 科学新闻2017，19，4： | 0 |
| 9 | Corrigendum to‘The power of“controllers”:Transposon-mediated duplicated genes evolve towards neofunctionalization’[Journal of Genetics and Genomics(2023)50,462–472]显示文摘This corrigendum clarifies information in the review‘The power of“controllers”:Transposon-mediated duplicated genes evolve towards neofunctionalization’by Ma et al.(2023).The word“controllers”throughout the paper should be corrected into“controlling elements”:1.The title‘The power of“controllers”:Transposon-mediated duplicated genes evolve towards neofunctionalization’should be corrected into‘The power of“controlling elements”:Transposon-mediated duplicated genes evolve towards neofunctionalization’. | Huijing Ma Mengxia Wang Yong E.Zhang Shengjun Tan | 2024 | Journal of Genetics and Genomics2024，51，1： | 0 |
| 10 | Smurfs have“fused”into the asymmetric division of stem cells显示文摘The asymmetric cell division is the way in which a stem cell divides into one daughter stem cell and one differentiated daughter cell.This process is one of the key principles of developmental biology that ensures the perpetual supply of stem cells while allowing a particular cell lineage to be populated.During Drosophila oogenesis,the fate of the daughter stem cell produced from the asymmetric division of germline stem cells(GSCs)is specified by Decapentaplegic(Dpp),but the other daughter cell has almost equal access to the Dpp signal.How Dpp signaling is inactivated in the differentiated daughter cell has been a deep mystery until a recent study,led by Dahua Chen of the Institute of Zoology,China(Xia et al.,2010),showed that the Dpp receptor,Thick vein(Tkv),is degraded specifically in the differentiated daughter cell by an HECT-domain ubiquitin E3 ligase,Smurf,in conjunction with a serine-threonine kinase Fused(Fu).This finding is as much revealing as it is surprising,because up until now Fu is considered a core member of the Hedgehog signaling pathway. | Steven Y.Cheng Ying E.Zhang | 2011 | Protein & Cell2011，2，1： | 0 |
| 11 | 胞嘧啶脱氨酶/5-氟胞嘧啶自杀基因治疗系统对恶性脑胶质瘤荷瘤裸鼠的抗肿瘤作用显示文摘目的评判胞嘧啶脱氨酶/5-氟胞嘧啶(CD/5-FC)自杀基因治疗系统对恶性脑胶质瘤的抗肿瘤效果。方法采用Lipofectamine2000^TM脂质体介导方法将CD基因转染U251恶性胶质瘤细胞系,并接种于裸鼠前臂皮下,成瘤后腹腔注射5-FC(每日500mg/kg体重)10d,观察荷瘤鼠肿瘤的生长情况,8周后比较转染组与对照组肿瘤的体积与重量,并进行病理形态学分析。结果U251细胞获得CD基因的成功转染,5-FC用于不同组别荷瘤裸鼠,8周后转染组肿瘤体积(0.09±0.03)cm^3和重量(0.28±0.11)g明显小于对照组(1.81±0.77)cm^3和(1.63±0.80)g;形态学揭示转染组肿瘤细胞出现明显的凋亡与坏死。结论裸鼠在体实验研究表明:CD/5-FC自杀基因治疗系统是治疗恶性脑胶质瘤行之有效的手段之一。 | 吕胜青 张克斌 刘学强 尹昌林 邱克军 Eric E.ZHANG 杨辉 | 2008 | 中华实验外科杂志2008，25，8： | 0 |
| 12 | The power of“controllers”:Transposon-mediated duplicated genes evolve towards neofunctionalization显示文摘Since the discovery of the first transposon by Dr.Barbara McClintock,the prevalence and diversity of transposable elements(TEs)have been gradually recognized.As fundamental genetic components,TEs drive organismal evolution not only by contributing functional sequences(e.g.,regulatory elements or“controllers”as phrased by Dr.McClintock)but also by shuffling genomic sequences.In the latter respect,TE-mediated gene duplications have contributed to the origination of new genes and attracted extensive interest.In response to the development of this field,we herein attempt to provide an overview of TEmediated duplication by focusing on common rules emerging across duplications generated by different TE types.Specifically,despite the huge divergence of transposition machinery across TEs,we identify three common features of various TE-mediated duplication mechanisms,including end bypass,template switching,and recurrent transposition.These three features lead to one common functional outcome,namely,TE-mediated duplicates tend to be subjected to exon shuffling and neofunctionalization.Therefore,the intrinsic properties of the mutational mechanism constrain the evolutionary trajectories of these duplicates.We finally discuss the future of this field including an in-depth characterization of both the duplication mechanisms and functions of TE-mediated duplicates. | Huijing Ma Mengxia Wang Yong E.Zhang Shengjun Tan | 2023 | Journal of Genetics and Genomics2023，50，7： | 0 |
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