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| 1 | Melanoma of the rectum: A rare entity显示文摘A 41-year-old man presented with a 6-mo history of changed defecation and rectal bleeding. A 3-cm polypoid tumor of the lower rectum was found at rectosigmoidos- copy, which proved to be a leiomyosarcoma upon biopsy. Dissemination studies did not show any metastases. He was underwent to an abdomino-perineal resection (APR). Histopathology of the specimen showed a melanoma (S-100 stain positive). Two years after the resection, me- tastases in the abdomen and right lung were found. He died one and half years later. Primary anorectal melano- ma is a rare and very aggressive disorder. According to current data, one should always perform a S-100 stain when anorectal sarcoma is suspected. A positive S-100 stain suggests the tumour to be most likely a melanoma. Subsequently, thorough dissemination studies need to be performed. Depending on the outcome of the dissemina- tion studies, a surgical resection has to be performed. Nowadays, a sphincter-saving local excision combined with adjuvant loco-regional radiotherapy should be pre- ferred in case of small tumors. The same loco-regional control is achieved with less 'loss of function' compared to non-sphincter saving surgery. Only in the case of large and obstructing tumors an abdomino-perineal resection is the treatment of choice. | PM van Schaik MF Ernst HA Meijer K Bosscha | 2008 | World Journal of Gastroenterology2008，14，10： | 3 |
| 2 | Vitamin D receptor: a new risk marker for clinical restenosis after percutaneous coronary intervention显示文摘 | Pascalle S Monraats Yue Fang Douwe Pons Nuno MM Pires Huibert AP Pols Aeilko H Zwinderman Moniek PM de Maat Pieter AF Doevendans Robbert J deWinter René A Tio Johannes Waltenberger Rune R Frants Paul HA Quax Arnoud van der Laarse Ernst E van der Wall Andr | 2010 | Expert Opinion on Therapeutic Targets2010，，： | 1 |
| 3 | Surface analysis of chemically-etched and plasma treated polyetheretherketone for biomedical applications显示文摘 | Ha S W Hauert R Ernst K H | 1997 | Surface and Coatings Technology1997，97，： | 1 |
| 4 | Outcome of colonic surgery in elderly patients with colon cancer显示文摘 | Hennans E van Schaik PM Prins HA Ernst MF Dautzenberg PJ Bosseha K | 2010 | J Oncol2010，2010，： | 1 |
| 5 | Structure of the conserved domain of ANAC,a member of the NAC family of transcription factors显示文摘 | Ernst HA Olsen AN Larsen S Leggio LL | | 0，，： | 1 |
| 6 | NAC transcription factors:Structurally distinct,functionally diverse显示文摘 | Olsen AN Ernst HA Leggio LL Skfiver K | | 0，，： | 1 |
| 7 | DNA-binding specificity and molecular functions of NAC transcription factors显示文摘 | OLSEN AN ERNST HA LO LEGGIO L etal | 2005 | Plant Science2005，169，4： | 1 |
| 8 | Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors 显示文摘 | Ernst HA Olsen AN Larsen S Lo Leggio L | 2004 | EMBO Rep2004，5，： | 1 |
| 9 | NAC transcription factors: structurally distinct, functionally diverse 显示文摘 | Olsen AN Ernst HA Leggio LL | 2005 | Trends Plant Sci2005，10，2： | 1 |
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