|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comparison of imaging-based and pathological dimensions in pancreatic neuroendocrine tumors显示文摘AIM To establish the ability of magnetic resonance(MR) and computer tomography(CT) to predict pathologic dimensions of pancreatic neuroendocrine tumors(Pan NET) in a caseload of a tertiary referral center.METHODS Patients submitted to surgery for Pan NET at the Surgical Unit of the Pancreas Institute with at least 1 preoperative imaging examination(MR or CT scan) from January 2005 to December 2015 were included and data retrospectively collected. Exclusion criteria were: multifocal lesions, genetic syndromes, microadenomas or mixed tumors, metastatic disease and neoadjuvant therapy. Bland-Altman(BA) and Mountain-Plot(MP) statistics were used to compare size measured by each modality with the pathology size. Passing-Bablok(PB) regression analysis was used to check the agreement between MR and CT.RESULTS Our study population consisted of 292 patients. Seventy-nine(27.1%) were functioning Pan NET. The mean biases were 0.17 ± 7.99 mm, 1 ± 8.51 mm and 0.23 ± 9 mm, 1.2 ± 9.8 mm for MR and CT, considering the overall population and the subgroup of non-functioning-Pan NET, respectively. Limits of agreement(LOA) included the vast majority of observations, indicating a good agreement between imaging and pathology. The MP further confirmed this finding and showed that the two methods are unbiased with respect to each other. Considering ≤ 2 cm non-functioning-Pan NET, no statistical significance was found in the size estimation rate of MR and CT(P = 0.433). PBR analysis did not reveal significant differences between MR, CT and pathology.CONCLUSION MR and CT scan are accurate and interchangeable imaging techniques in predicting pathologic dimensions of Pan NET. | Salvatore Paiella Harmony Impellizzeri Elisabetta Zanolin Giovanni Marchegiani Marco Miotto Anna Malpaga Riccardo De Robertis Mirko D'Onofrio Borislav Rusev Paola Capelli Sara Cingarlini Giovanni Butturini Maria Vittoria Davì Antonio Amodio Claudio BassiAldo Scarpa Roberto Salvia Luca Landoni | 2017 | World Journal of Gastroenterology2017，23，17： | 4 |
| 2 | Nuclear imaging in detection and monitoring of cardiotoxicity显示文摘Cardiotoxicity as a result of cancer treatment is a novel and serious public health issue that has a significant impact on a cancer patient’s management and outcome.The coexistence of cancer and cardiac disease in the same patient is more common because of aging population and improvements in the efficacy of antitumor agents.Left ventricular dysfunction is the most typical manifestation and can lead to heart failure.Left ventricular ejection fraction measurement by echocardiography and multigated radionuclide angiography is the most common diagnostic approach to detect cardiac damage,but it identifies a late manifestation of myocardial injury.Early non-invasive imaging techniques are needed for the diagnosis and monitoringof cardiotoxic effects.Although echocardiography and cardiac magnetic resonance are the most commonly used imaging techniques for cardiotoxicity assessment,greater attention is focused on new nuclear cardiologic techniques,which can identify high-risk patients in the early stage and visualize the pathophysiologic process at the tissue level before clinical manifestation.The aim of this review is to summarize the role of nuclear imaging techniques in the non-invasive detection of myocardial damage related to antineoplastic therapy at the reversible stage,focusing on the current role and future perspectives of nuclear imaging techniques and molecular radiotracers in detection and monitoring of cardiotoxicity. | Carmen D’Amore Paola Gargiulo Stefania Paolillo Angela Maria Pellegrino Tiziana Formisano Antonio Mariniello Giuseppe DellaRatta Elisabetta Iardino Marianna D’Amato Lucia La Mura Irma Fabiani Flavia Fusco Pasquale Perrone Filardi | 2014 | World Journal of Radiology2014，6，7： | 2 |
| 3 | The emerging role of probiotics in neurodegenerative diseases:new hope for Parkinson’s disease?显示文摘Neurodegenerative disease etiology is still unclear,but different contributing factors,such as lifestyle and genetic factors are involved.Altered components of the gut could play a key role in the gut-brain axis,which is a bidirectional system between the central nervous system and the enteric nervous system.Variations in the composition of the gut microbiota and its function between healthy people and patients have been reported for a variety of human disorders comprising metabolic,autoimmune,cancer,and,notably,neurodegenerative disorders.Diet can alter the microbiota composition,affecting the gutbrain axis function.Different nutraceutical interventions have been devoted to normalizing gut microbiome dysbiosis and to improving biological outcomes in neurological conditions,including the use of probiotics.Preclinical and clinical investigations discussed in this review strengthen the correlation between intestinal microbiota and brain and the concept that modifying the microbiome composition may improve brain neurochemistry,modulating different pathways.This review will discuss the potential use of probiotics for Parkinson’s disease prevention or treatment or as adjuvant therapy,confirming that gut microbiota modulation influences different pro-survival pathways.Future investigations in Parkinson’s disease should consider the role of the gut-brain axis and additional comprehension of the underlying mechanisms is extremely necessary. | Vanessa Castelli Michele d’Angelo Massimiliano Quintiliani Elisabetta Benedetti Maria Grazia Cifone Annamaria Cimini | 2021 | Neural Regeneration Research2021，16，4： | 2 |
| 4 | Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease显示文摘 | Renata D’Incà Elisabetta Pont Vincenza Leo Antonio Ferronato Walter Fries Maria Grazia Vettorato Diego Martines Giacomo Carlo Sturniolo | 2007 | International Journal of Colorectal Disease2007，，4： | 2 |
| 5 | Lack of in vitro protection by a common sunscreen ingredient on UVA-induced cytotoxicity in keratinocytes显示文摘 | Tatiana A Elisabetta D Maurizio B | 2004 | Toxicology2004，203，： | 1 |
| 6 | Neurological complications of celiac disease and autoimmune mechanisms: A prospective study显示文摘 | Chiara Briani Gabriella Zara Armin Alaedini Francesca Grassivaro Susanna Ruggero Elisabetta Toffanin Maria Paola Albergoni Milena Luca Bruno Giometto Mario Ermani Franca De Lazzari Anna D’Odorico Leontino Battistin | 2008 | Journal of Neuroimmunology2008，，1： | 1 |
| 7 | Multicenter evaluation of an enzyme immunoassay (Platelia? Aspergillus) for the detection of Aspergillus antigen in serum显示文摘 | Gianluigi Lombardi Claudio Farina Stefano Andreoni Domenico D'Antonio Elisabetta Faggi Esther Manso Aldo Mazzoni | 2002 | Mycopathologia2002，，3： | 1 |
| 8 | Non-invasive investigation in patients with inflammatory joint disease显示文摘Gut inflammation can occur in 30%-60% of patients with spondyloarthropathies.However, the presence of such gut inflammation is underestimated, only 27% of patients with histological evidence of gut inflammation have intestinal symptoms, but subclinical gut inflammation is documented in two-thirds of patients with inflammatory joint disease.There are common genetic and immunological mechanisms behind concomitant inflammation in the joints and intestinal tract.A number of blood tests, e.g.erythrocyte sedimentation rate, orosomucoid, C-reactive protein, and white cell and platelet counts, are probably the most commonly used laboratory markers of inflammatory disease, however, these tests are difficult to interpret in arthropathies associated with gut inflammation, since any increases in their blood levels might be attributable to either the joint disease or to gut inflammation.Consequently, it would be useful to have a marker capable of separately identifying gut inflammation.Fecal proteins, which are indirect markers of neutrophil migration in the gut wall, and intestinal permeability, seem to be ideal for monitoring intestinal inflammation:they are easy to measure non-invasively and are specific for intestinal disease in the absence of gastrointestinal infections.Alongside the traditional markers for characterizing intestinal inflammation, there are also antibodies, in all probability generated by the immune response to microbial antigens and auto-antigens, which have proved useful in establishing the diagnosis and assessing the severity of the condition, as well as the prognosis and the risk of complications.In short, noninvasive investigations on the gut in patients with rheumatic disease may be useful in clinical practice for a preliminary assessment of patients with suspected intestinal disease. | Elisabetta Dal Pont Renata D’Incà Antonino Caruso Giacomo Carlo Sturniolo | 2009 | World Journal of Gastroenterology2009，15，20： | 1 |
| 9 | Notch 1 overexpres- sion inhibits osteoblastogenesis by suppressing Wnt/beta- catenin but not bone morphogenetic protein signaling显示文摘 | Valerie D Elisabetta G Leah P | 2006 | J Biol2006，281，10： | 1 |
| 10 | Follow-up of a large population of asymptomatic/oligosymptomatic hyperckemic subjects显示文摘 | Elisabetta D’Adda Monica Sciacco Maria Elisa Fruguglietti Veronica Crugnola Valeria Lucchini Filippo Martinelli-Boneschi Chiara Zecca Costanza Lamperti Giacomo Pietro Comi Nereo Bresolin Maurizio Moggio Alessandro Prelle | 2006 | Journal of Neurology2006，，11： | 1 |
| 11 | The safety of a novel sublingual rush induction phase for latex desensitization显示文摘 | Eustachio N Elisabetta D Gianfranco C | 2010 | Current Medical Research & Opinion2010，26，8： | 1 |
| 12 | Short-Term, High-Dose Atorvastatin Pretreatment to Prevent Contrast-Induced Nephropathy in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention (from the ARMYDA-CIN [Atorvastatin for Reduction of MYocardial Damage during An显示文摘 | Giuseppe Patti Elisabetta Ricottini Annunziata Nusca Giuseppe Colonna Vincenzo Pasceri Andrea D’Ambrosio Antonio Montinaro Germano Di Sciascio | 2011 | The American Journal of Cardiology2011，，1： | 1 |
| 13 | Nitrite metabolism in Debaryomyces hansenii TOB-Y7, a yeast strain involved in tobacco fermentation 显示文摘 | Giovanni V Michele D G Elisabetta C | 2007 | Applied Microbi- ologyandBiotechnology2007，75，： | 1 |
| 14 | Total antioxidant capacity in patients with varicoceles显示文摘 | Elisabetta Meucci M D | 2003 | Fertile and Sterility2003，79，： | 1 |
| 15 | Numb is a suppressor of Hedgehog signalling and targets Glil for Itch - dependent ubiquiti- nation 显示文摘 | Lucia D Elisabetta F Azzura G | 2006 | Nature Cell Biology2006，8，12： | 1 |
| 16 | The histone-like protein H1-S and the response of tomato leaves to water deficit显示文摘 | Gabriella S S Michela D M Elisabetta | 2003 | Journal of Expermental Botany2003，55，394： | 1 |
| 17 | Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination显示文摘 | Lucia D Elisabetta F Azzura G | 2006 | Nat Cell Biol2006，8，12： | 1 |
| 18 | Percutaneous interventions in patients with acute ischemic stroke related to obstructive atherosclerotic disease or dissection of the extracranial carotid artery 显示文摘 | Nikas D Reimers B Elisabetta M | 2007 | J Endovasc Ther2007，14，3： | 1 |
| 19 | Methods for screening tumors for p53 status and therapeutic explication显示文摘 | Apollonia Tullo Anna Maria D' Erchia Elisabetta Sbis | 2003 | Expert Rev Mol Diagn2003，3，3： | 1 |
| 20 | Endotjelial adherens junctions:implications in the control of vascular permeability and angiogensis 显示文摘 | Elisabetta D | 1996 | J Clin Inves1996，98，9： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员