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| 1 | Appraisal of Clinical Practice Guidelines for Ischemic Stroke Management in Chinese Medicine with Appraisal of Guidelines for Research and Evaluation Instrument:A Systematic Review显示文摘Objective:To systematically review the clinical practice guidelines(CPGs)for ischemic stroke in Chinese medicine(CM)with the Appraisal of Guidelines for Research and Evaluation(AGREE II)instrument.Methods:CM CPGs for ischemic stroke were searched in 5 online databases and hand-searches in CPGrelated handbooks published from January 1990 to December 2012.The CPGs were categorized into evidence based(EB)guideline,consensus based with no explicit consideration of evidence based(CB-EB)guideline and consensus based(CB)guideline according to the development method.Three reviewers independently appraised the CPGs based on AGREE II instrument,and compared the CPGs'recommendations on CM pattern classification and treatment.Results:Five CM CPGs for ischemic stroke were identified and included.Among them,one CPG was EB guideline,two were CB guidelines and two were CB-EB guidelines.The quality score of the EB guideline was higher than those of the CB-EB and CB guidelines.Five CM patterns in the CPGs were recommended in the EB CPG.The comprehensive protocol of integrative Chinese and Westem medicine recommended in the EB CPG was mostly recommended for ischemic stroke in the CPGs.The recommendations varied based on the CM patterns.Conclusion:The quality of EB CPG was higher than those of CB and CB-EB CPGs in CM for ischemic stroke and integrative approaches were included in CPGs as major interventions. | 宇文亚 史楠楠 韩学杰 高颖 徐建龙 刘大胜 Bacon Ng Dora Tsui 钟丽丹 Eric Ziea 卞兆祥 吕爱平 | 2015 | Chinese Journal of Integrative Medicine2015，21，9： | 10 |
| 2 | A truncated hepatitis E virus ORF2 protein expressed in tobacco plastids is immunogenic in mice显示文摘瞄准:表示 23-ku pE2 到花费有效地,肝炎 E 病毒(HEV ) 的 3'-portion 包括的 E2 碎片编码的最有希望的子单元疫苗打开读物框架 2 (ORF2 ) 在烟草的质体(Nicotiana 烟 cv。SR1 ) ,在质体调查 transgene 表示和 pE2 累积,并且评估反在老鼠的导出质体的 pE2 的遗传因子的效果。方法:包含米饭 psbA 倡导者驾驶的 E2 碎片的指向质体的向量 pRB94-E2 被构造。在进烟草质体的交货之上,这构造能在质体染色体在 psaB-trnfM 和 trnG-psbC 碎片开始相应再结合,并且导致在二碎片之间插入的 transgene。pRB94-E2 与一个 biolistic 粒子轰炸方法被交付,并且转变质体的工厂被获得在补充 spectinomycin 的媒介上跟随炮轰的叶纸巾的新生。改革工厂的 Transplastomic 地位被 PCR 和南部的污点分析证实, transgene 表示被北污点分析调查,并且 pE2 的累积被 ELISA 测量。而且,蛋白浸出物被用来使老鼠免疫,并且在使免疫的老鼠的浆液样品的 pE2 反应的抗体的存在被 ELISA 学习。结果:PCR 和南部的污点分析证实的 Transplastomic 线能活跃地抄录 E2 mRNA。pE2 多肽象 13.27 microg/g 一样高被积累到水平新鲜叶子。pE2 能刺激使免疫的老鼠产生 pE2 特定的抗体。结论:HEV-E2 碎片能被插入到质体染色体,导出的 recombinant pE2 抗原是在老鼠遗传因子的反。因此,质体可以是为 HEV 疫苗的划算的生产的新奇来源。 | Yuan-Xiang Zhou Maggie Yuk-Ting Lee James Ming-Him Ng Mee-Len Chye Wing-Kin Yip Sze-Yong Zee Eric Lam | 2006 | World Journal of Gastroenterology2006，12，2： | 10 |
| 3 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 4 | Abscisic acid perception and signaling: structura mechanisms and applications显示文摘不利环境条件是对农业产量的威胁因此在生计,健康和经济上施加全球效果。Abscisic 酸(骆驼毛的织物) 是调整不能生活的压力忍耐的重要植物荷尔蒙,从而允许种应付环境压力。以前,试图开发发信号的内在的骆驼毛的织物被困难在真正的骆驼毛的织物受体的鉴定妨碍了的机制的完全的理解。骆驼毛的织物受体的 PYR/PYL/RCAR 家庭的发现因此在克服这些障碍的努力代表了一个主要里程碑;从那以后,许多结构、功能的研究提供了详细卓见进从骆驼毛的织物感觉到骆驼毛的织物应答的基因抄写的激活的过程。这理解骆驼毛的织物感觉的机制并且发信号在压力抵抗的庄稼的遗传工程以及在新合成骆驼毛的织物收缩筋的设计用作最近的、初步的开发的基础,它为应力公差的农业改进保持大诺言。 | Ley Moy NG Karsten MELCHER Bin Tean TEH H Eric XU | 2014 | Acta Pharmacologica Sinica2014，35，5： | 4 |
| 5 | A MULTIPLE INTELLIGENT AGENT SYSTEM FOR CREDIT RISK PREDICTION VIA AN OPTIMIZATION OF LOCALIZED GENERALIZATION ERROR WITH DIVERSITY显示文摘公司破产每年在损失花费了十亿美元到银行。因此承认风险预言是一个银行的贷款赞同决定过程的关键部分。为信用风险预言的传统的金融模型为 describingtoday 在金融健康和一个公司的潜在的破产之间的复杂关系不再是足够的。Inthis 工作,一个多重分类器系统(在一个多重聪明的代理人系统嵌入) 被建议预言一个公司的金融健康。在我们的模型,每个单个代理人(分类器) 基于公司的仅仅偏爱的信息在信用风险的可能性上做预言。每代理人是一位专家,但是限制了知识(由特征代表了) 关于公司。所有代理人的决定一起被联合形成最后的信用风险预言。实验证明我们的模型用 benchmarking Compustat 美国公司数据集超过另外的存在方法。 | Daniel S. YEUNG Wing W. Y. NG Aki P. F. CHAN Patrick P. K. CHAN Michael FIRTH Eric C. C. TSANG | 2007 | Journal of Systems Science and Systems Engineering2007，16，2： | 2 |
| 6 | A Phase II Trial of Gemcitabine Plus Capecitabine for Metastatic Renal Cell Cancer Previously Treated With Immunotherapy and Targeted Agents显示文摘 | Nizar M. Tannir Peter F. Thall Chaan S. Ng Xuemei Wang Leiko Wooten Arlene Siefker-Radtke Paul Mathew Lance Pagliaro Christopher Wood Eric Jonasch | 2007 | The Journal of Urology2007，，： | 1 |
| 7 | Comparative evaluation of four methods for assay of Cis - and Trans - resveratrol 显示文摘 | Goldberg DM Eric NG | 1997 | Amer J Eno Viticu1997，48，2： | 1 |
| 8 | Lifetime prediction of a blue PE100 water pipe显示文摘 | Eric M. Hoàng David Lowe | 2008 | Polymer Degradation and Stability2008，，8： | 1 |
| 9 | Type II enteropathy‐associated T‐cell lymphoma: A multicenter analysis from the Asia Lymphoma Study Group显示文摘 | Eric Tse Harinder Gill Florence Loong Seok Jin Kim Siok‐Bian Ng Tiffany Tang Young‐Hyeh Ko Wee‐Joo Chng Soon‐Thye Lim Won Seog Kim Yok‐Lam Kwong | 2012 | Am J Hematol2012，，7： | 1 |
| 10 | Production fragmentation and business-cycle Co- movement显示文摘 | ERIC C Y Ng | 2010 | Journal of International Economics2010，，82： | 1 |
| 11 | Successful Adaptation of Targeted Gene Panel Next-Generation Sequencing in Regional Hospital in Hong Kong: Genomic Diagnosis of SCN2A-Related Seizure Disorder显示文摘 | Han-Chih Hencher Lee Nike Kwai-Cheung Lau Chun-Wing Yeung Sui-Fun Grace Ng Kin-Cheong Eric Yau Chloe Miu Mak | 2018 | Chinese Medical Journal2018，，18： | 1 |
| 12 | Partial protection against enterovirus 71 ( EV71 ) infec- tion in a mouse model immunized with recombinant new- castle disease virus capsids displaying the EV71 VP1 fragment 显示文摘 | Ch'ng Wei-Choong Stanbridge Eric J Ong Kien-Chai | 2011 | J of Medical Virology2011，83，10： | 1 |
| 13 | Evaluation of lightweight titanium-coated polypropylene mesh (TiMesh) for laparoscopic repair of large hiatal hernias显示文摘 | Eric J. Hazebroek Ada Ng David H. K. Yong Hayley Berry Steven Leibman Garett S. Smith | 2008 | Surgical Endoscopy2008，，11： | 1 |
| 14 | A Comparison of Postoperative Complications in Open versus Robotic Cystectomy显示文摘 | Casey K. Ng Eric C. Kauffman Ming-Ming Lee Brandon J. Otto Alyse Portnoff Josh R. Ehrlich Michael J. Schwartz Gerald J. Wang Douglas S. Scherr | 2009 | European Urology2009，，2： | 1 |
| 15 | Production Fragmentation and Busi- ness-Cycle Comovement显示文摘 | Ng Eric C Y | 2010 | Journal of Internation- al Economics2010，82，1： | 1 |
| 16 | Lifetime Prediction of a Blue PE100 Water Pipe显示文摘 | HOA'NG ERIC M LOWE David | 2008 | Polymer Degradation and Stabili- ty2008，93，： | 1 |
| 17 | Medical Management of Cronkhite-Canada Syndrome显示文摘 | ERIC WARD HERBERT C. WOLFSEN CHRISTINE NG | 2002 | Southern Medical Journal2002，，2： | 1 |
| 18 | Orthotopic neobladder and subsequent renal transplantation显示文摘 | Toni Nimeh Christopher S Ng David A Goldfarb Eric A Klein | 2002 | Urology2002，，5： | 1 |
| 19 | Additive Technology for EU Ecolabel Formulations显示文摘Currently,Bio-lubricants are still regarded as niche products.Within the global lubricant market,however,the area of environmentally acceptable fluids represents one of the fast growing markets with an estimated annual growth of more than 6% per year.This growth is supported by various market drivers such as legal regulations,public subsidies and the implementation of national or international labeling schemes.With the implementation of the European Ecolabel for lubricants in 2005,a common standard specifying ecological and performance requirements for Bio-lubricants was defined.Applying for the EU Ecolabel requires a comprehensive assessment,not only of the final formulation,but also of the additives used.Additives are required to meet specifications for oxidation and thermal stability,as well as to impart metal protection(of both steel and yellow metals),thus improving corrosion protection and wear performance of the formulation.Therefore,it is challenging in terms of formulation technology to develop the right formulation that meets the technical specifications as well as the stringent requirements of the EU-Ecolabel.The paper describes how,by using ester base fluids and additives currently available in the market,lubricants can be developed to meet the technical and eco-toxicological requirements of the EU-Ecolabel,approaching the performance levels of lubricants formulated with traditional base fluids. | Eric Nehls Tassilo Habereder Edward Ng | 2009 | 润滑油2009，24，3： | 0 |
| 20 | An overview of flavonoids from Sophora flavescens(kushen)with some emphasis on the anticancer properties of kurarinone and sophoraflavanone G显示文摘In this overview,the current knowledge of the constituents of flavonoids isolated from the roots of Sophora flavescens(kushen)is updated.Flavonoids consist of several classes,such as flavanones,flavonols,chalcones,isoflavones,biflavonoids,flavanols,and flavones.The most common compounds are kurarinone(KRN),sophoraflavanone G(SFG),2′-methoxykurarinone,kuraridine,isoxanthohumol,and formononetin.KRN and SFG are two major flavanones with more vital anticancer properties than other flavonoids.From the literature,the cytotoxic values of KRN and SFG are variable and depend on the type of cancer cells tested.The anticancer activities of these two flavonoids involve different molecular mechanisms.Clinical trials are needed before anticancer drugs from KRN and SFG can be developed. | Eric Wei Chiang Chan Ying Ki Ng Hung Tuck Chan Siu Kuin Wong | 2023 | Journal of Chinese Pharmaceutical Sciences2023，32，8： | 0 |
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