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| 1 | Irritable bowel syndrome subtypes differ in body awareness, psychological symptoms and biochemical stress markers显示文摘AIM: To elucidate the differences in somatic, psycho-logical and biochemical pattern between the subtypes of irritable bowel syndrome (IBS). METHODS: Eighty IBS patients, 30 diarrhoea pre-dominant (D-IBS), 16 constipation predominant (C-IBS) and 34 alternating IBS (A-IBS) underwent physi-otherapeutic examinations for dysfunctions in body movements and awareness and were compared to an apparently healthy control group (AHC). All groups an-swered questionnaires for gastrointestinal and psycho-logical symptoms. Biochemical variables were analysed in blood. RESULTS: The D-IBS group showed less body aware-ness, less psychological symptoms, a more normal sense of coherence and psychosocial rating as well as higher C-peptide values. C-IBS had a higher degree of body dysfunction and psychological symptoms, as well as the lowest sense of coherence compared to controls and D-IBS. They also demonstrated the most elevated prolactin levels. A-IBS had the lowest degree of body disturbance, deteriorated quality of life and affected bi-ochemical pattern. All subtypes had higher pain scores compared to controls. In addition they all had signifi -cantly increased triglycerides and elevated morning cortisol levels, however, without statistical signifi cance compared with the controls.CONCLUSION: IBS subtypes showed different pro-files in body awareness, somatic and psychological symptoms and in biochemical variables. D-IBS differed compared to the other groups by lowered body aware-ness, less psychological symptoms and a higher sense of coherence and elevated C-peptide values. C-IBS and A-IBS subtypes suffered more from depression and anxiety, associated with a lower quality of life. These differences may be important and will be taken into account in our treatment of these patients. | Elsa M Eriksson Kristina I Andrén Henry T Eriksson Gran K Kurlberg | 2008 | World Journal of Gastroenterology2008，14，31： | 7 |
| 2 | Aspects of the non-pharmacological treatment of irritable bowel syndrome显示文摘Irritable bowel syndrome(IBS) is one of the most commonly diagnosed gastrointestinal conditions. It represents a significant healthcare burden and remains a clinical challenge. Over the years IBS has been described from a variety of different perspectives; from a strict illness of the gastrointestinal tract(medical model) to a more complex multi-symptomatic disorder of the brain-gut axis(biopsychosocial/psychosomatic model). In this article we present aspects of the pathophysiology and the non-pharmacological treatment of IBS based on current knowledge. Effects of conditioned stress and/or traumatic influences on the emotional system(top-down) as well as effects on the intestine through stressors,infection,inflammation,food and dysbiosis(bottom-up) can affect braingut communication and result in dysregulation of the autonomic nervous system(ANS),playing an important role in the pathophysiology of IBS. Conditioned stress together with dysregulation of the autonomic nervous system and the emotional system may involve reactions in which the distress inside the body is not recognized due to low body awareness. This may explain why patients have difficulty identifying their symptoms despite dysfunction in muscle tension,movement patterns,and posture and biochemical functions in addition to gastrointestinal symptoms. IBS shares many features with other idiopathic conditions,such as fibromyalgia,chronic fatigue syndrome and somatoform disorders. The key to effective treatment is a thorough examination,including a gastroenterological examination to exclude other diseases along with an assessment of body awareness by a body-mind therapist. The literature suggests that early interdisciplinary diagnostic cooperation between gastroenterologists and body-mind therapists is necessary. Re-establishing balance in the ANS is an important component of IBS treatment. This article discusses the current knowledge of body-mind treatment,addressing the topic from a practical point of view. | Elsa Maria Eriksson Kristina Ingrid Andrén Goran Karl Kurlberg Henry Ture Eriksson | 2015 | World Journal of Gastroenterology2015，21，40： | 6 |
| 3 | Decommissioning at Kristineberg mine, Sweden 显示文摘 | Lindvall M Eriksson N Ljungberg J | 1999 | Mining and the Environment Ⅱ1999，，3： | 1 |
| 4 | Resolving postoperative neuroinflammation and cognitive decline 显示文摘 | Terrando N Eriksson LI Ryu JK | 2011 | Ann Neurol2011，70，6： | 1 |
| 5 | Genetic determinants of dabigatran plasma levels and their relation to bleeding 显示文摘 | Pare G Eriksson N Lehr T | 2013 | Circulation2013，127，13： | 1 |
| 6 | Association of warfarin dose with genes involved in its action and metabolism显示文摘 | Wadelius M Chen LY Eriksson N | 2007 | Hum Gen- et2007，121，1： | 1 |
| 7 | Dabigatran etexilate for prevention of venous thromboembolism after total hip replacement: a randomised double- blind, non-inferiority trial显示文摘 | Eriksson B Dnhl OE Roseneher N | 2007 | Lancet2007，370，9591： | 1 |
| 8 | Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials:Safe Implementation of Thrombolysis in Stroke-Monitoring Study(SITS-MOST)显示文摘 | Wahlgren N Ahmed N Eriksson N | 2008 | Stroke2008，39，12： | 1 |
| 9 | real-time detection of inorganic pyrophosphatase activity 显示文摘 | Eriksson J Karamohamed S Method for Nyre n P | 2001 | Analyti Biochem2001，293，1： | 1 |
| 10 | User Experience of Trip Arrangements - A Comparison of Mobile Device and Computer Users 显示文摘 | Eriksson N | 2012 | International Journal of E -Services and Mobile Applications2012，4，2： | 1 |
| 11 | Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial显示文摘 | Eriksson BI Dahl OE Rosencher N | 2007 | Lancet2007，370，9591： | 1 |
| 12 | Dabigutran ete- xilate for prevention of venous thromboembolism after total hip re- placement: a randomised doubleblind, non - inferiority trial 显示文摘 | ERIKSSON B DNHL O E ROSENEHER N | 2007 | Lancet2007，370，9591： | 1 |
| 13 | Association of warfarindose with genes involved in its action and metabolism 显示文摘 | Wadelius M Chen LY Eriksson N | 2007 | HumCenet2007，，： | 1 |
| 14 | Relationship between plasma fibrinogen and coronary heart disease in women显示文摘 | Egberg N Wainala S | 1999 | Arterioscler Thromb Vasc B iol1999，19，7： | 1 |
| 15 | Photochemical decomposition of 15 polybrominated diphenyl ether congeners in ethanolPwater显示文摘 | ERIKSSON J GREEN N MARSH G | 2004 | Environ Sci Technol2004，38，： | 1 |
| 16 | Neighborhood walkability, physical activity, and walking behavior: the Swedish Neighborhood and Physical Activity (SNAP) study 显示文摘 | Sundquist K Eriksson U Kawakami N | 2011 | Soc Sei Med2011，72，8： | 1 |
| 17 | Neonatal expo- sure to perfluorooctane sulfonate (PFOS) and perfluo- rooctanoic acid (PFOA) causes neurobehavioural defects in adult mice 显示文摘 | Johansson N Fredriksson A Eriksson P | 2008 | Neurotoxicology2008，29，1： | 1 |
| 18 | The CTA1-DD vaccine adjuvant binds to human B cells and potentiates their T cell stimulating ability 显示文摘 | Eriksson A Lycke N | 2003 | Vaccine2003，22，2： | 1 |
| 19 | Estimation of the warfarin dose with clinical and pharmacogenetic data 显示文摘 | Klein TE Altman RB Eriksson N | 2009 | N Engl J Med2009，360，8： | 1 |
| 20 | Association of warfarindose with genes involved in its action and metabo-lism显示文摘 | Wadelius M Chen LY Eriksson N | 2007 | Hum Genet2007，121，： | 1 |
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