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| 1 | Long-term Outcomes of 1,730 Calcaneal Fractures: Systematic Review of the Literature显示文摘 | Ewout S. Veltman Job N. Doornberg Sjoerd A.S. Stufkens Jan S.K. Luitse Michel P.J. van den Bekerom | 2013 | The Journal of Foot and Ankle Surgery2013，，4： | 4 |
| 2 | Lateral subtalar dislocation: Case report and review of the literature显示文摘A case of complicated lateral subtalar dislocation is presented and the literature concerning this injury is reviewed. Subtalar joint dislocations are rare and often the result of a high-energy trauma. Complications include avascular necrosis of the talus, infection, posttraumatic osteoarthritis requiring arthrodesis and chronic subtalar instability. Negative prognostic factors include lateral and complicated dislocations, total talar extrusions, and associated fractures. A literature search was performed to identify studies describing outcome after lateral subtalar joint dislocation. Eight studies including fifty patients could be included, thirty out of 50 patients suffered a complicated injury. Mean follow-up was fifty-five months. Ankle function was reported as good in all patients with closed lateral subtalar dislocation.Thirteen out of thirty patients with complicated lateral subtalar joint dislocation developed a complication.Avascular necrosis was present in nine patients with complicated injury. Four patients with complicated lateral subtalar dislocation suffered deep infection requiring treatment with antibiotics. In case of uncomplicated lateral subtalar joint dislocation, excellent functional outcome after closed reduction and immobilization can be expected. In case of complicated lateral subtalar joint dislocation immediate reduction, wound debridement and if necessary(external) stabilisation are critical. Up to fifty percent of patients suffering complicated injury are at risk of developing complications such as avascular talar necrosis and infection. | Ewout S Veltman Ernst JA Steller Philippe Wittich Jort Keizer | 2016 | World Journal of Orthopedics2016，7，9： | 4 |
| 3 | Diagnostic value of drain amylase for detecting intrathoracic leakage after esophagectomy显示文摘AIM:To investigate the value of elevated drain amylase concentrations for detecting anastomotic leakage(AL) after minimally invasive Ivor-Lewis esophagectomy(MIILE).METHODS:This was a retrospective analysis of prospectively collected data in two hospitals in the Netherlands. Consecutive patients undergoing MI-ILE were included. A Jackson-Pratt drain next to the dorsal side of the anastomosis and bilateral chest drains were placed at the end of the thoracoscopic procedure. Amylase levels in drain fluid were determined in all patients during at least the first four postoperative days. Contrast computed tomography scans and/or endoscopic imaging were performed in cases of a clinically suspected AL. Anastomotic leakage was defined as any sign of leakage of the esophago-gastric anastomosis on endoscopy,re-operation,radiographic investigations,post mortal examination or when gastro-intestinal contents were found in drain fluid. Receiver operator characteristic curves were used to determine the cut-off values. Sensitivity,specificity,positive predictive value,negative predictive value,risk ratio and overall test accuracy were calculated for elevated drain amylase concentrations.RESULTS:A t o t a l o f 8 9 p a t ie n t s w e re in c lu d e d between March 2013 and August 2014. No differences in group characteristics were observed between patients with and without AL,except for age. Patients with AL were older than were patients without AL(P = 0.01). One patient(1.1%) without AL died within 30 d after surgery due to pneumonia and acute respiratory distress syndrome. Anastomotic leakage that required any intervention occurred in 15 patients(16.9%). Patients with proven anastomotic leakage had higher drain amylase levels than patients without anastomotic leakage [median 384 IU/L(IQR 34-6263) vs median 37 IU/L(IQR 26-66),P = 0.003]. Optimal cut-off values on postoperative days 1,2,and 3 were 350 IU/L,200 IU/L and 160 IU/L,respectively. An elevated amylase level was found in 9 of the 15 patients with AL. Five of these 9 patients had early elevations of their amylase levels,with a median of 2 d(IQR 2-5) before signs and symptoms occurred.CONCLUSION:Measurement of drain amylase levels is an inexpensive and easy tool that may be used to screen for anastomotic leakage soon after MI-ILE. However,clinical validation of this marker is necessary. | Gijs HK Berkelmans Ewout A Kouwenhoven Boudewijn JJ Smeets Teus J Weijs Luis C Silva Corten Marc J van Det Grard AP Nieuwenhuijzen Misha DP Luyer | 2015 | World Journal of Gastroenterology2015，21，30： | 3 |
| 4 | Comparison of the 6th and 7th Editions of the UICC-AJCC TNM Classification for Esophageal Cancer显示文摘 | Koen Talsma Pieter Hagen Brechtje Grotenhuis Ewout Steyerberg Hugo Tilanus Jan Lanschot Bas Wijnhoven | 2012 | Annals of Surgical Oncology2012，，7： | 2 |
| 5 | Aberrant p53 protein expression is associated with an increased risk of neoplastic progression in patients with Barrett’s oesophagus显示文摘 | Florine Kastelein Katharina Biermann Ewout W Steyerberg Joanne Verheij Marit Kalisvaart Leendert H J Looijenga Hans A Stoop Laurens Walter Ernst J Kuipers Manon C W Spaander Marco J Bruno | 2013 | Gut2013，，12： | 2 |
| 6 | Retroperitoneal Adrenalectomy: Open or Endoscopic?显示文摘 | H. Jaap Bonjer Erwin van der Harst Ewout W. Steyerberg Wouter W. de Herder Geert Kazemier Robert S.A. Mohammedamin Hajo A. Bruining | 1998 | World Journal of Surgery1998，，12： | 1 |
| 7 | Patient age and outcome following severe traumatic brian injury: An analysis of 5600 pa tients显示文摘 | Chantal WP Ewout WS Anneke J | 2003 | J Neurosurg2003，99，4： | 1 |
| 8 | Nonsteroidal Anti-Inflammatory Drugs and Statins Have Chemopreventative Effects in Patients With Barrett’s Esophagus显示文摘 | Florine Kastelein Manon C.W. Spaander Katharina Biermann Ewout W. Steyerberg Ernst J. Kuipers Marco J. Bruno | 2011 | Gastroenterology2011，，6： | 1 |
| 9 | Patient age and outcome following severe traumatic brain injury:an analysis of 5600 patients显示文摘 | Chantal WP Ewout WS Anneke J | 2003 | Neurosurg2003，99，： | 1 |
| 10 | Patient age and outcome following severe traumatic brain injury:an analysis of 5600 patients显示文摘 | Chantal WP Ewout WS Anneke J | 2003 | J Neurosurg2003，99，： | 1 |
| 11 | Probing the praetor frontier for basis pur- suit solution显示文摘 | EWOUT V D MICHAEL P F | 2008 | Society for Industrial Applied Mathematics2008，31，2： | 1 |
| 12 | Predictors of Outcome in Patients With Acute Coronary Syndromes Without Persistent ST-Segment Elevation: Results From an International Trial of 9461 Patients显示文摘 | Eric Boersma Karen S. Pieper Ewout W. Steyerberg Robert G. Wilcox Wei-Ching Chang Kerry L. Lee K. Martijn Akkerhuis Robert A. Harrington Jaap W. Deckers Paul W. Armstrong A. Michael Lincoff Robert M. Califf Eric J. Topol Maarten L. Simoons | 2000 | Circulation: Journal of the American Heart Association2000，，22： | 1 |
| 13 | Patient age and outcome following severe traumatic brain injury:An analysis of 5 600 pa- tients显示文摘 | Chantal WP Ewout W Anneke J | 2003 | J Ncurosurg2003，99，4： | 1 |
| 14 | Factors That Predict Response of Patients With Hepatitis B e Antigen–Positive Chronic Hepatitis B to Peginterferon-Alfa显示文摘 | Erik H.C.J. Buster Bettina E. Hansen George K.K. Lau Teerha Piratvisuth Stefan Zeuzem Ewout W. Steyerberg Harry L.A. Janssen | 2009 | Gastroenterology2009，，6： | 1 |
| 15 | Patient age and outcomefollowing severe traumatic brian injury:An analysis of 5600 patie-nts显示文摘 | Chantal WP Ewout WS Anneke J | 2003 | J Neurosurg?2003，99，4： | 1 |
| 16 | Patient age and outcome following severe traumatic brain injury:An analysis of 5600 patients显示文摘 | Chantal WP Ewout WS Anneke J | 2003 | J Neurosurg2003，99，： | 1 |
| 17 | Proton Pump Inhibitors Reduce the Risk of Neoplastic Progression in Patients with Barrett’s Esophagus显示文摘 | Florine Kastelein Manon C.W. Spaander Ewout W. Steyerberg Katharina Biermann Vera E. Valkhoff Ernst J. Kuipers Marco J. Bruno | 2012 | Clinical Gastroenterology and Hepatology2012，，： | 1 |
| 18 | Ataxin-2 Modulates the Levels of Grb2 and Src but Not Ras Signaling显示文摘 | Jessica Drost David Nonis Florian Eich Oliver Leske Ewa Damrath Ewout R. Brunt Isabel Lastres-Becker Rolf Heumann Joachim Nowock Georg Auburger | 2013 | Journal of Molecular Neuroscience2013，，1： | 1 |
| 19 | Probing the pareto frontier for basis pursuit solutions 显示文摘 | Ewout V D B Micheal P F | 2008 | SIAM Journal on Scien- tific Computing2008，31，2： | 1 |
| 20 | Anatomical and clinical characteristics to guide decision making between coronary artery bypass surgery and percutaneous coronary intervention for individual patients: development and validation of SYNTAX score II显示文摘 | Vasim Farooq David van Klaveren Ewout W Steyerberg Emanuele Meliga Yvonne Vergouwe Alaide Chieffo Arie Pieter Kappetein Antonio Colombo David R Holmes Michael Mack Ted Feldman Marie-Claude Morice Elisabeth St?hle Yoshinobu Onuma Marie-angèle Morel Hector | 2013 | The Lancet2013，，9867： | 1 |
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