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| 1 | Prognostic factors in patients with advanced cholangiocarcinoma: Role of surgery, chemotherapy and body mass index显示文摘AIM: To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS: A retrospective review of the medical records of 55 patients diagnosed with cholangio- carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to determine the impact of surgery, chemotherapy, body mass index, bilirubin level and other factors on survival. RESULTS: The median survival of all patients was 8.57 mo (0.03-105.2). Univariate analysis showed that low bilirubin level (< 10 mg/dL), radical surgery and chemotherapy administration were significantly associated with better survival (P = 0.012, 0.038 and 0.038, respectively). In subgroup analysis on patients who had no surgery, chemotherapy administration prolonged median survival significantly (17.0 mo vs 3.5 mo, P = 0.001). Multivariate analysis identifiedonly low bilirubin level < 10 mg/dL and chemotherapy administration as independent predictors associated with better survival (P < 0.05). CONCLUSION: Our data show that palliative and postoperative chemotherapy as well as a bilirubin level < 10 mg/dL are independent predictors of a significant increase in survival in patients with cholangiocarcinoma. | Mirna H Farhat Ali I Shamseddine Ayman N Tawil Ghina Berjawi Charif Sidani Wael Shamseddeen Kassem A Barada | 2008 | World Journal of Gastroenterology2008，14，20： | 9 |
| 2 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 3 | Eco-friendly and cleaner process for isolation of essential oil using microwave energy experimental and theoretical study显示文摘 | Farhat A Ginies C Romdhance M | 2009 | Journal of Chromatography A2009，1216，26： | 1 |
| 4 | Comparative performance, blood chemistry, and carcass composition of two line of Peking ducks reared mixed or separated by sex 显示文摘 | Farhat A Chavez E R | 2000 | Poultry Sci2000，79，： | 1 |
| 5 | Partitioned analysis of coupled mechanical systems显示文摘 | FELIPPA C A PARK K C FARHAT C | 2001 | Computer Methods in Applied Mechanics and Engineering2001，190，： | 1 |
| 6 | Acquired protein C deficiency in a child with acute myelogenous leukemia, splenic, renal, and intestinal infarction显示文摘 | Roula A Farah Khalil S Jalkh Hussein Z Farhat Paul E Sayad Adel M Kadri | 2011 | Blood Coagulation & Fibrinolysis2011，，2： | 1 |
| 7 | The association of bone mineral density measures with incident cardiovascular disease in older adults 显示文摘 | FARHAT G N NEWMAN A B SUTTON T K | 2007 | Osteoporosis Int2007，18，： | 1 |
| 8 | Drying kinetics and characteristic drying curve of lightly salted sardine ( sardinella aurita) 显示文摘 | Bellagha S Amami E Farhat A | 2002 | Drying Technology2002，20，7： | 1 |
| 9 | Start- up of UASB reactors treating municipal wastewaterand effect of temperature/sludge age and hydraulic retention time (HRT) on its performance 显示文摘 | Hina Rizvi a Nasir Ahmad b Farhat Abbas | 2014 | Arabian Journal d Chemistry2014，1，26： | 1 |
| 10 | Two-level domain decomposition methods with Lagrange multipliers for the fast iterative solution of acoustic scattering problems显示文摘 | FARHAT C MACEDO A LESOINNE M | 2000 | Computer Methods in Applied Mechanics and Engineering2000，184，： | 1 |
| 11 | Study of the solar drying of grapes by three different processes显示文摘 | Fadhel A Koolia S Farhat A | 2005 | Desalination2005，185，2： | 1 |
| 12 | Expression,prognostic and predictive impact of VEGF and bFGF in nonsmall cell lung cancer显示文摘 | Farhat F S Tfayli A Fakhruddin N | | 0，，02： | 1 |
| 13 | 22 week assessment of bladder acellular matrix as a bladder augmentation material in a porcine model显示文摘 | Brown A L Farhat W Merguerian P A | 2002 | Biomaterials2002，23，10： | 1 |
| 14 | The effect of sugars on the diffusion of water in starch gels: a pulsed field gradient NMR study显示文摘 | FARHAT 1 A LOISEL E SAEZ P | 1997 | International Journal of Food Science and Technology1997，32，5： | 1 |
| 15 | Expression,prognostic and predictive impact of VEGF and bFGF in non-small cell lung cancer显示文摘 | Farhat FS Tfayli A Fakhruddin N | | 0，，02： | 1 |
| 16 | Retroperitoneal laparoscopic PS open partial nephroureterectomy in children,Intemational显示文摘 | El-Ghoneimi A Farhat W Bolduc S | 2003 | BJU2003，91，： | 1 |
| 17 | Green supply chains with carbon trading and environmental sourcing:formulation and life cycle assessment显示文摘 | ABDALLAH T FARHAT A DIABAT A | 2012 | Applied Mathematical Modelling2012，36，9： | 1 |
| 18 | Postoperative hypoxaemia : continuous extradural infusion of bupivacaine and morphine vs patient-controlled analgesia with intravenous morphine 显示文摘 | Motamed C Spencer A Farhat F | 1998 | Br J Anaesth1998，80，6： | 1 |
| 19 | Numerical simulation of cooling tower coupled with heat pump sys- tem associated with single house using TRNSYS 显示文摘 | CHARGUI R SAMMOUDA H FARHAT A | 2013 | Energy Conversion and Management2013，75，： | 1 |
| 20 | Determining electron temperature and density in a hydrogen microwave plasma显示文摘 | SCOTT C D FARHAT S GICQUEL A | 1993 | Journal of Ther- mophysics & Heat Transfer1993，10，3： | 1 |
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